Primary Site >> Colorectal Cancer
Gene >> CD44
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Ref: Scc-1, a novel colon cancer susceptibility gene in the mouse: linkage to CD44 (Ly-24, Pgp-1) on chromosome 2. PMID: 1347918 Ref: Significance of CD44 gene products for cancer diagnosis and disease evaluation. PMID: 1357452 |
Ref: CD44 splice variants: expression during lymphocyte activation and tumor progression. PMID: 7504454 Ref: CD44 participates in the adhesion of human colorectal carcinoma cells to laminin and type IV collagen. PMID: 7504563 Ref: [CD44, the hyaluronic acid cell receptor. Its role in neoplastic invasion and metastatic dissemination]. PMID: 7515731 Ref: Expression of CD44 variant proteins in human colorectal cancer is related to tumor progression. PMID: 7691404 Ref: Expression of CD44R1 adhesion molecule in colon carcinomas and metastases. PMID: 8095628 Ref: A human homologue of the rat metastasis-associated variant of CD44 is expressed in colorectal carcinomas and adenomatous polyps. PMID: 8416989 |
Ref: Potential use of soluble CD44 in serum as indicator of tumor burden and metastasis in patients with gastric or colon cancer. PMID: 7506122 Ref: Ligand binding specificity of alternatively spliced CD44 isoforms. Recognition and binding of hyaluronan by CD44R1. PMID: 7510702 Ref: Normal colonic epithelium adheres to carcinoembryonic antigen and type IV collagen. PMID: 7513665 Ref: CD44 expression in colorectal adenomas is an early event occurring prior to K-ras and p53 gene mutation. PMID: 7513984 Ref: Alternative splicing of CD44 pre-mRNA in human colorectal tumors. PMID: 7513991 Ref: H blood group antigen carried by CD44V modulates tumorigenicity of rat colon carcinoma cells. PMID: 7525057 Ref: Colorectal cancer prognosis and expression of exon-v6-containing CD44 proteins. PMID: 7526103 Ref: [Metastasis-related genes]. PMID: 7526801 Ref: Expression of CD44 splice variants during lymphocyte activation and tumor progression. PMID: 7530151 Ref: Positive relationship between expression of CD44 and hepatic metastases in colorectal cancer. PMID: 7537507 Ref: CD44 isoforms in metastatic cancer. PMID: 7544777 |
Ref: A novel co-stimulatory T cell antigen co-expressed on renal cell carcinoma. PMID: 7495750 Ref: Comparison of immunohistochemistry and RT-PCR for detection of CD44v-expression, a new prognostic factor in human breast cancer. PMID: 7530237 Ref: Expression of mutant p53 protein and CD44 variant proteins in colorectal tumorigenesis. PMID: 7534253 Ref: Alternative RNA splicing of the hyaluronic acid receptor CD44 in the normal human brain and in brain tumors. PMID: 7536236 Ref: Expression of CD44 variant exons 8-10 in colorectal cancer and its relationship to metastasis. PMID: 7538103 Ref: Colorectal cancer prognosis and expression of exon-v6-containing CD44 proteins. PMID: 7539876 Ref: Colorectal cancer prognosis and expression of exon-v6-containing CD44 proteins. PMID: 7539877 Ref: Abnormal retention of intron 9 in CD44 gene transcripts in human gastrointestinal tumors. PMID: 7545538 Ref: Are CD44 variant isoforms involved in human tumour progression? PMID: 7553660 Ref: Restoration of CD44H expression in colon carcinomas reduces tumorigenicity. PMID: 7574929 Ref: CD44 isoforms correlate with cellular differentiation but not with prognosis in human breast cancer. PMID: 7585612 Ref: MHC class I and class II determinants and some adhesion molecules are engaged in the regulation of nitric oxide production in vitro by human monocytes stimulated with colon carcinoma cells. PMID: 7586750 Ref: CD44 expression patterns in breast and colon tumors: a PCR-based study of splice variants. PMID: 7591309 Ref: [Expression of CD44 metastatic variant mRNA in colorectal carcinomas and its role in tumor metastasis and invasion]. PMID: 7630010 Ref: [Expression of CD44 alternative splicing variants in lung cancer]. PMID: 7630011 Ref: Genetic alterations in human gastrointestinal cancers. The application to molecular diagnosis. PMID: 7889467 Ref: Identification of CD44 splice variant in Korean colorectal cancers and cell lines. PMID: 8527042 Ref: Relation between stage, grade, proliferation, and expression of p53 and CD44 in adenomas and carcinomas of the colorectum. PMID: 8567994 Ref: CD44 hyaluronate binding influences growth kinetics and tumorigenicity of human colon carcinomas. PMID: 8570172 Ref: The modulation of granulomatous tissue and tumour angiogenesis by diclofenac in combination with hyaluronan (HYAL EX-0001). PMID: 8867646 Ref: Alterations of p53 and k-ras genes in human colorectal-cancer with ulcerative-colitis. PMID: 21556601 Ref: Expression of messenger-RNA cd44 splice variants in primary colon-cancer and liver metastases. PMID: 21597863 |
Ref: Expression of variant CD44-messenger RNA in colorectal adenocarcinomas and adenomatous polyps in humans. PMID: 8566581 Ref: CD44 exon variant 6 epitope and hyaluronate synthase are expressed on HT29 human colorectal carcinoma cells in a SCID mouse model of metastasis formation. PMID: 8605724 Ref: Evaluation of CD44 transcription variants in human digestive tract carcinomas and normal tissues. PMID: 8608952 Ref: Keratan sulfate modification of CD44 modulates adhesion to hyaluronate. PMID: 8621620 Ref: Expression of a CD44 variant containing exons 8 to 10 is a useful independent factor for the prediction of prognosis in colorectal cancer patients. PMID: 8648366 Ref: A CD44 variant exon 6 epitope as a prognostic indicator in breast cancer. PMID: 8654608 Ref: Detection of exfoliated carcinoma cells in colonic luminal washings by identification of deranged patterns of expression of the CD44 gene. PMID: 8655705 Ref: Alternatively spliced variants of the cell adhesion molecule CD44 and tumour progression in colorectal cancer. PMID: 8695347 Ref: Bcl-2, p53, CD44, and CD44v6 isoform expression in neuroendocrine tumors of the lung. PMID: 8733762 Ref: Abnormal expression of the human CD44 gene in early colorectal malignancy with special reference to variant exon 9 (9v). PMID: 8763262 Ref: Cellular distribution of CD44 gene transcripts in colorectal carcinomas and in normal colonic mucosa. PMID: 8763263 Ref: [Expression of CD44 isoforms--a new histopathologic parameter in colorectal carcinoma?]. PMID: 8767329 Ref: Early detachment of colon carcinoma cells during CD95(APO-1/Fas)-mediated apoptosis. I. De-adhesion from hyaluronate by shedding of CD44. PMID: 8769429 Ref: O-linked glycosylation modifies CD44 adhesion to hyaluronate in colon carcinoma cells. PMID: 8858111 Ref: The positive relationship between the expression of CD44 variant 6 and prognosis in colorectal cancer. PMID: 8883258 Ref: Adhesion receptors in malignant transformation and dissemination of gastrointestinal tumors. PMID: 8893333 Ref: Analysis of anomalous CD44 gene expression in human breast, bladder, and colon cancer and correlation of observed mRNA and protein isoforms. PMID: 8909242 Ref: Semiquantitative Detection of Abnormal CD44 Transcripts in Colon Carcinomas by Reverse Transcription-Polymerase Chain Reaction Enzyme-linked Immunosorbant Assay (RT-PCR ELISA). PMID: 10462557 Ref: CD44 with variant exons 8-10 in colorectal tumors. PMID: 21544409 |
Ref: Expression of CD44 splice variants in colorectal cancer. PMID: 9117309 Ref: Increase of rat colon carcinoma cells tumorigenicity by alpha(1-2) fucosyltransferase gene transfection. PMID: 9134429 Ref: Role of integrins and evidence for two distinct mechanisms mediating human colorectal carcinoma cell interaction with peritoneal mesothelial cells and extracellular matrix. PMID: 9177905 Ref: Immunophenotyping of human HT29 colon cancer cell primary tumours and their metastases in severe combined immunodeficient mice. PMID: 9184853 Ref: Detection of circulating tumour cells and nodal metastasis by reverse transcriptase-polymerase chain reaction technique. PMID: 9189103 Ref: p53 and CD44 as clinical markers of tumour progression in colorectal carcinogenesis. PMID: 9248852 Ref: Expression of CD44, ICAM-1 and N-CAM in colorectal cancer. Correlation with the tumor stage and the phenotypical characteristics of tumor-infiltrating lymphocytes. PMID: 9252653 Ref: Changes in CD44 expression during carcinogenesis of the mouse colon. PMID: 9316589 Ref: Soluble protein encoded by CD44 variant exons 8-10 in the serum of patients with colorectal cancer. PMID: 9361612 Ref: CD44 expression in astrocytic tumors. PMID: 9436970 Ref: Immunophenotype of human HT29 colon cancer cell metastases in the lungs of scid mice: spontaneous versus artificial metastases. PMID: 9561026 Ref: Inhibition of liver metastasis formation by anti-CD44 variant exon 9 monoclonal antibody. PMID: 21528332 Ref: Expression of variant CD44, exon 6 in patients with metastatic pulmonary tumor. PMID: 21590147 |
Ref: Molecular changes during the genesis of human gliomas. PMID: 9407626 Ref: [Molecular diagnosis of gastrointestinal cancers]. PMID: 9474927 Ref: CD44 splice variants as prognostic markers in colorectal cancer. PMID: 9489913 Ref: CD44 expression in the stromal matrix of colorectal cancer: association with prognosis. PMID: 9516948 Ref: CD44v6 is not a prognostic factor in primary breast cancer. PMID: 9541692 Ref: Expression of CD44 and variant proteins in human colorectal cancer and its relevance for prognosis. PMID: 9548625 Ref: Acquisition of cell adhesion and induction of focal adhesion kinase of human colon cancer Colo 201 cells by retinoic acid-induced differentiation. PMID: 9566310 Ref: Abnormal expression of CD44 variants in the exfoliated cells in the feces of patients with colorectal cancer. PMID: 9609756 Ref: Soluble CD44 and CD44v6 serum levels in patients with colorectal cancer are independent of tumor stage and tissue expression of CD44v6. PMID: 9625129 Ref: CD44V6 expression in human colorectal carcinoma. PMID: 9635685 Ref: Clinical significance of serum levels of CD44 variant exons 8-10 protein in colorectal cancer. PMID: 9658313 Ref: Expression of antisense CD44 variant 6 inhibits colorectal tumor metastasis and tumor growth in a wound environment. PMID: 9721884 Ref: Clinical significance of combined immunohistochemical detection of CD44v and sialyl LeX expression for colorectal cancer patients undergoing curative resection. PMID: 9732216 Ref: [Expression of CD44 variant v6 in breast carcinoma and its relationship with other parameters of tumor biology]. PMID: 9732832 Ref: [Expression of variant CD44 in colorectal cancer and its relationship to liver metastasis]. PMID: 9742519 Ref: Overexpression of CD44: a useful independent predictor of prognosis in patients with colorectal carcinomas. PMID: 9754757 Ref: Engagement of variant CD44 confers resistance to anti-integrin antibody-mediated apoptosis in a colon carcinoma cell line. PMID: 9759519 Ref: Expression of cell adhesion molecule CD44 and sialyl Lewis A in gastric carcinoma and colorectal carcinoma in association with hepatic metastasis. PMID: 9772282 Ref: Multiple intron retention occurs in tumor cell CD44 mRNA processing. PMID: 9777953 Ref: Ratio of CD44 epithelial variant to CD44 hematopoietic variant is a useful prognostic indicator in gastric and colorectal carcinoma. PMID: 9839501 Ref: Differences in the migration capacity of primary human colon carcinoma cells (SW480) and their lymph node metastatic derivatives (SW620). PMID: 9839620 Ref: No evidence for cancer-related CD44 splice variants in primary and metastatic colorectal cancer. PMID: 9849461 Ref: Comparison of CD44 expression in early colorectal carcinomas of the de novo and ex adenoma types. PMID: 9849854 Ref: Decreased expression of CD44 splicing variants in advanced colorectal carcinomas. PMID: 9893637 Ref: CD44 expression in colorectal cancer. PMID: 9928409 Ref: Differentiation of a colon cancer cell line on a reconstituted basement membrane in vitro. PMID: 10319025 |
Ref: Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway. PMID: 10027409 Ref: Soluble CD44 variant 6 as a prognostic indicator in patients with colorectal cancer. PMID: 10202279 Ref: Evaluation of soluble CD44 in patients with breast and colorectal carcinomas and non-Hodgkin's lymphoma. PMID: 10425314 Ref: Soluble CD44: quantification and molecular repartition in plasma of patients with colorectal cancer. PMID: 10471052 Ref: CD44 stimulation induces integrin-mediated adhesion of colon cancer cell lines to endothelial cells by up-regulation of integrins and c-Met and activation of integrins. PMID: 10485493 Ref: Expression of adhesion molecules in hepatic metastases of colorectal carcinoma: relationship to primary tumours and prognosis after hepatic resection. PMID: 10530497 Ref: Receptor for hyaluronan-mediated motility and CD44 expressions in colon cancer assessed by quantitative analysis using real-time reverse transcriptase-polymerase chain reaction. PMID: 10551329 Ref: Glycosylation alterations of cells in late phase apoptosis from colon carcinomas. PMID: 10561459 Ref: Influence of cytokines on the expression of fas ligand and CD44 splice variants in colon carcinoma cells. PMID: 10567875 Ref: Clinicopathological significance of the expression of CD44v2 in colorectal cancer. PMID: 10650786 Ref: Prognostic evaluation of metallothionein expression in human colorectal neoplasms. PMID: 10711249 Ref: [Are there differences between ex adenoma and de novo colorectal carcinomas?]. PMID: 10714204 Ref: [Antigen CD44: does the presence of its isoforms have significance for diagnosis for diagnosis of colorectal cancer?]. PMID: 10786369 |
Ref: CD44 glycoproteins in colorectal cancer: expression, function, and prognostic value. PMID: 10549358 Ref: Immunohistochemical expression of the CD44 variant 6 in colorectal adenocarcinoma. PMID: 10648079 Ref: CD44s expression in human colon carcinomas influences growth of liver metastases. PMID: 10699925 Ref: Limitations of CD44v6 amplification for the detection of tumour cells in the blood of colorectal cancer patients. PMID: 10755402 Ref: Do the expression of CD44, apoptosis and thymidylate synthase inhibition rate correlate with the efficacy of chemotherapy in colorectal cancer? PMID: 10769701 Ref: Expression of CD44, vascular endothelial growth factor, and proliferating cell nuclear antigen in severe venous invasional colorectal cancer and its relationship to liver metastasis. PMID: 10795863 Ref: Decreased expression of CD44, alpha-catenin, and deleted colon carcinoma and altered expression of beta-catenin in ulcerative colitis-associated dysplasia and carcinoma, as compared with sporadic colon neoplasms. PMID: 10951334 Ref: Loss of standard type of CD44 expression in invaded area as a good indicator of lymph-node metastasis in colorectal carcinoma. PMID: 11005492 Ref: Expression of c-Met and heparan-sulfate proteoglycan forms of CD44 in colorectal cancer. PMID: 11073815 Ref: The significance of CD44 variants expression in colorectal cancer and its regional lymph nodes. PMID: 11194197 |
Ref: Introduction of antisense CD44S CDNA down-regulates expression of overall CD44 isoforms and inhibits tumor growth and metastasis in highly metastatic colon carcinoma cells. PMID: 11149422 Ref: Sodium hyaluronate enhances colorectal tumour cell metastatic potential in vitro and in vivo. PMID: 11167875 Ref: Activated T lymphocytes bind in situ to stromal tissue of colon carcinoma but lack adhesion to tumor cells. PMID: 11169447 Ref: Age-associated changes in gene expression patterns in the duodenum and colon of rats. PMID: 11240159 Ref: Molecular markers are predictors of recurrence and survival in patients with Dukes B and Dukes C colorectal adenocarcinoma. PMID: 11330579 Ref: [Genetic changes in liver metastasis of colorectal cancer and their clinical application]. PMID: 11393998 Ref: A CD44 survival pathway triggers chemoresistance via lyn kinase and phosphoinositide 3-kinase/Akt in colon carcinoma cells. PMID: 11431370 Ref: Cell surface-expressed Thomsen-Friedenreich antigen in colon cancer is predominantly carried on high molecular weight splice variants of CD44. PMID: 11447138 Ref: Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling. PMID: 11470825 Ref: CD44s expression mitigates the phenotype of human colorectal cancer hepatic metastases. PMID: 11724345 Ref: Possible contribution of CD44 variant 6 and nuclear beta-catenin expression to the formation of budding tumor cells in patients with T1 colorectal carcinoma. PMID: 11745187 Ref: Heparan sulfate enhances invasion by human colon carcinoma cell lines through expression of CD44 variant exon 3. PMID: 11751503 Ref: MRNA expression of genes altered by 5-azacytidine treatment in cancer cell lines is associated with clinicopathological parameters of human cancers. PMID: 11768609 Ref: CD44 expression in colorectal cancer. An immunohistochemical study including correlation with cathepsin D immunoreactivity and some tumour clinicopathological features. PMID: 11820582 Ref: Prognostic value of CD44 expression in colorectal carcinomas. PMID: 11911305 |
Ref: Beta-catenin--a linchpin in colorectal carcinogenesis? PMID: 11839557 Ref: Proteolytic cleavage of the CD44 adhesion molecule in multiple human tumors. PMID: 11839564 Ref: Expression of CD44 variants in colorectal carcinoma quantified by real-time reverse transcriptase-polymerase chain reaction. PMID: 11873246 Ref: Expression of CD44v6 has no prognostic value in patients with colorectal cancer. PMID: 11961731 Ref: Expression of CD44v5 and -v6 in Barrett's carcinoma is not increased compared to that in nondysplastic Barrett's mucosa. PMID: 12009784 Ref: CD44v6 is not relevant in colorectal tumour progression. PMID: 12018451 Ref: TNFalpha and IL-8 regulate the expression and function of CD44 variant proteins in human colon carcinoma cells. PMID: 12090473 Ref: Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway. PMID: 12145277 Ref: Co-expression of CD44v3 and heparanase is correlated with metastasis of human colon cancer. PMID: 12165810 Ref: Impact of laparoscopic CO2-insufflation on tumor-associated molecules in cultured colorectal cancer cells. PMID: 12189480 Ref: Prediction of distant metastasis by using reverse transcriptase-polymerase chain reaction for epithelial and variant CD44 mRNA in the peripheral blood of patients with colorectal cancer. PMID: 12215164 Ref: Evaluation of clinicopathological factors and the correlation between the adhesion molecule CD44 variant 9 expression and pulmonary metastases from colorectal cancers. PMID: 12222916 Ref: Butyrate down-regulates CD44 transcription and liver colonisation in a highly metastatic human colon carcinoma cell line. PMID: 12439723 Ref: Impact of laparoscopic and conventional surgery on Kupffer cells, tumor-associated CD44 expression, and intrahepatic tumor spread. PMID: 12470109 Ref: Expression of CD44s in human colorectal cancer. PMID: 12515996 |
Ref: Clinical utility of grading criteria for submucosal invasion in the prognosis of T1 colorectal carcinomas. PMID: 12560920 Ref: Effect of laparotomy and CO(2) pneumoperitoneum on tumor growth of human colon carcinoma and expression pattern of tumor-associated proteins in the SCID mouse. PMID: 12684833 Ref: Coprocytobiology: on the nature of cellular elements from stools in the pathophysiology of colonic disease. PMID: 12702972 Ref: Downregulation of CD44v6 in colorectal carcinomas is associated with hypermethylation of the CD44 promoter region. PMID: 12782013 Ref: Expression of proliferating cell nuclear antigen and CD44 variant exon 6 in primary tumors and corresponding lymph node metastases of colorectal carcinoma with Dukes' stage C or D. PMID: 12854146 Ref: Motility of colon cancer cells: modulation by CD44 isoform expression. PMID: 14516773 Ref: Evaluation of CD44 variant 6 expression and clinicopathological factors in pulmonary metastases from colon carcinoma. PMID: 14534711 Ref: CD44 variant exon 6 expressions in colon cancer assessed by quantitative analysis using real time reverse transcriptase-polymerase chain reaction. PMID: 14534719 Ref: [Role of CD44 and MT1-MMP in colorectal cancer invasion and metastasis]. PMID: 14574866 Ref: Role of VEGF and CD44v6 in differentiating benign from malignant ascites. PMID: 14606105 Ref: Laminin-5 gamma 2 chain and matrix metalloproteinase-2 may trigger colorectal carcinoma invasiveness through formation of budding tumor cells. PMID: 14666611 Ref: [Effects of sodium hyaluronate on growth and adhesion of two human colorectal cancer cell lines in vitro]. PMID: 14712518 Ref: Osteopontin identified as colon cancer tumor progression marker. PMID: 14744111 |
Ref: CD44 variant 6 expression predicts response to treatment in advanced colorectal cancer. PMID: 14654900 Ref: Levels of v5 and v6 CD44 splice variants in serum of patients with colorectal cancer are not correlated with pT stage, histopathological grade of malignancy and clinical features. PMID: 14966921 Ref: Elevated transcript level of hyaluronan synthase1 gene correlates with poor prognosis of human colon cancer. PMID: 15065603 Ref: Comparative analysis of cell adhesion molecules, cell cycle regulatory proteins, mismatch repair genes, cyclooxygenase-2, and DPC4 in carcinomas arising in inflammatory bowel disease and sporadic colon cancer. PMID: 15069531 Ref: CD44 negatively regulates apoptosis in murine colonic epithelium via the mitochondrial pathway. PMID: 15126101 Ref: Elevated TGF-beta1 secretion and down-modulation of NKG2D underlies impaired NK cytotoxicity in cancer patients. PMID: 15187109 Ref: CD44 promotes resistance to apoptosis in human colon cancer cells. PMID: 15215046 Ref: Hyaluronan facilitates invasion of colon carcinoma cells in vitro via interaction with CD44. PMID: 15231668 Ref: Expression and localization of membrane-type-1 matrix metalloproteinase, CD 44, and laminin-5gamma2 chain during colorectal carcinoma tumor progression. PMID: 15517370 Ref: Evaluation of prognosis for malignant rectal gastrointestinal stromal tumor by clinical parameters and immunohistochemical staining. PMID: 15622586 Ref: Glycoprotein CD44 variant 4 expression in tumour epithelial cells of patients with colorectal cancer. PMID: 15638368 Ref: Molecule CD44 variant 10 expression in lymphocytes infiltrating tumour tissues and epithelial cells in patients with colorectal cancer. PMID: 15638386 Ref: CD44s expression in resectable colorectal carcinomas and surrounding mucosa. PMID: 15641486 Ref: Osteopontin regulates multiple functions contributing to human colon cancer development and progression. PMID: 15679049 |
Ref: Hyaluronan constitutively regulates ErbB2 phosphorylation and signaling complex formation in carcinoma cells. PMID: 15632176 Ref: Osteopontin silencing by small interfering RNA suppresses in vitro and in vivo CT26 murine colon adenocarcinoma metastasis. PMID: 15661802 Ref: Apoptosis and release of CD44s in bleomycin-treated L132 cells. PMID: 15844216 Ref: Prognostic evaluation of CD44 expression in correlation with bcl-2 and p53 in colorectal cancer. PMID: 15871560 Ref: CD44 on LS174T colon carcinoma cells possesses E-selectin ligand activity. PMID: 15994957 Ref: Gene expression profiling in chemoresistant variants of three cell lines of different origin. PMID: 16080509 Ref: Upregulation and dephosphorylation of cofilin: modulation by CD44 variant isoform in human colon cancer cells. PMID: 16229833 Ref: Laminin alpha5 chain metastasis- and angiogenesis-inhibiting peptide blocks fibroblast growth factor 2 activity by binding to the heparan sulfate chains of CD44. PMID: 16288042 Ref: Dentin matrix protein 1 enhances invasion potential of colon cancer cells by bridging matrix metalloproteinase-9 to integrins and CD44. PMID: 16357164 |
Ref: Endoglin (CD105) expression in angiogenesis of colon cancer: analysis using tissue microarrays and comparison with other endothelial markers. PMID: 16177881 Ref: Variant isoforms of CD44 are P- and L-selectin ligands on colon carcinoma cells. PMID: 16352650 Ref: Profiling of the tetraspanin web of human colon cancer cells. PMID: 16467180 Ref: HCELL is the major E- and L-selectin ligand expressed on LS174T colon carcinoma cells. PMID: 16565092 Ref: Peanut lectin stimulates proliferation of colon cancer cells by interaction with glycosylated CD44v6 isoforms and consequential activation of c-Met and MAPK: functional implications for disease-associated glycosylation changes. PMID: 16571666 Ref: Anti-idiotype antibody induced cellular immunity in mice transgenic for human carcinoembryonic antigen. PMID: 16895556 Ref: Comparison of CD44 expression in primary tumours and metastases of colorectal cancer. PMID: 16969488 Ref: Organ-specific endoglin (CD105) expression in the angiogenesis of human cancers. PMID: 17096728 Ref: Immunohistochemical expression of bcl-2 in UICC stage I and III colorectal carcinoma patients: correlation with c-erbB-2, p53, ki-67, CD44, laminin and collagen IV in evaluating prognostic significance. PMID: 17219742 |
Ref: Influence of intraperitoneal application of taurolidine/heparin on expression of adhesion molecules and colon cancer in rats undergoing laparoscopy. PMID: 17109891 Ref: Selectin ligand expression regulates the initial vascular interactions of colon carcinoma cells: the roles of CD44v and alternative sialofucosylated selectin ligands. PMID: 17135256 Ref: Surgery-derived reactive oxygen species produced by polymorphonuclear leukocytes promote tumor recurrence: studies in an in vitro model. PMID: 17196986 Ref: Evaluation of risk of liver metastasis in colorectal adenocarcinoma based on the combination of risk factors including CD10 expression: multivariate analysis of clinicopathological and immunohistochemical factors. PMID: 17273728 Ref: Instillation of taurolidine/heparin after laparotomy reduces intraperitoneal tumour growth in a colon cancer rat model. PMID: 17337889 Ref: A multivariate analysis of adhesion molecules expression in assessment of colorectal cancer. PMID: 17443723 Ref: The role of osteopontin in tumor progression and metastasis in breast cancer. PMID: 17548669 Ref: Phenotypic characterization of human colorectal cancer stem cells. PMID: 17548814 Ref: A complex of EpCAM, claudin-7, CD44 variant isoforms, and tetraspanins promotes colorectal cancer progression. PMID: 17579117 Ref: CD44 regulates cell migration in human colon cancer cells via Lyn kinase and AKT phosphorylation. PMID: 17599831 Ref: Suppression of human colon cancer tumors in nude mice by siRNA CD44 gene therapy. PMID: 17945212 Ref: Soluble CD44 secretion contributes to the acquisition of aggressive tumor phenotype in human colon cancer cells. PMID: 17945213 Ref: [Identification of colorectal cancer, adenoma, and inflammatory bowel disease specific gene expression patterns using whole genomic oligonucleotide microarray system]. PMID: 17959550 |
Ref: Interactions between colon cancer cells and hepatocytes in rats in relation to metastasis. PMID: 18208563 Ref: The dual role of CD44 as a functional P-selectin ligand and fibrin receptor in colon carcinoma cell adhesion. PMID: 18234849 Ref: [Spheres isolated from Colo205 cell line possess cancer stem-like cells under serum-free culture condition]. PMID: 18250051 Ref: Hyaluronan constitutively regulates activation of COX-2-mediated cell survival activity in intestinal epithelial and colon carcinoma cells. PMID: 18326857 Ref: Carcinoembryonic antigen and CD44 variant isoforms cooperate to mediate colon carcinoma cell adhesion to E- and L-selectin in shear flow. PMID: 18375392 Ref: L-selectin-mediated lymphocyte-cancer cell interactions under low fluid shear conditions. PMID: 18385135 Ref: Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/+) mice attenuates intestinal tumorigenesis. PMID: 18483247 Ref: CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors. PMID: 18497886 Ref: Galectin-9 suppresses tumor metastasis by blocking adhesion to endothelium and extracellular matrices. PMID: 18579572 Ref: Inhibition of fibroblast growth factor 19 reduces tumor growth by modulating beta-catenin signaling. PMID: 18593907 Ref: Human pancreatic cancer stem cells: implications for how we treat pancreatic cancer. PMID: 18607507 Ref: Does hyaluronic acid stimulate tumor growth after endoscopic mucosal resection? PMID: 18637056 Ref: Hyaluronan, CD44, and cyclooxygenase-2 in colon cancer. PMID: 18661347 Ref: CD133+CD44+ population efficiently enriches colon cancer initiating cells. PMID: 18663533 Ref: Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity. PMID: 18765800 Ref: Inflammation, adenoma and cancer: objective classification of colon biopsy specimens with gene expression signature. PMID: 18776587 Ref: CD44 is of functional importance for colorectal cancer stem cells. PMID: 18980968 Ref: Suppression of invasive properties of colorectal carcinoma SW480 cells by 15-hydroxyprostaglandin dehydrogenase gene. PMID: 19034772 Ref: Evaluation of CD44 and CD44v6 in colorectal carcinoma patients: soluble forms in relation to tumor tissue expression and metastasis. PMID: 19333790 |
Ref: Biomolecular characterization of CD44-fibrin(ogen) binding: distinct molecular requirements mediate binding of standard and variant isoforms of CD44 to immobilized fibrin(ogen). PMID: 19004834 Ref: Age-related increase in colorectal cancer stem cells in macroscopically normal mucosa of patients with adenomas: a risk factor for colon cancer. PMID: 19010307 Ref: Cancer stem cell marker expression in hepatocellular carcinoma and liver metastases is not sufficient as single prognostic parameter. PMID: 19026485 Ref: Characterization of a subpopulation of colon cancer cells with stem cell-like properties. PMID: 19072981 Ref: Podocalyxin-like protein is an E-/L-selectin ligand on colon carcinoma cells: comparative biochemical properties of selectin ligands in host and tumor cells. PMID: 19118161 Ref: Delivery of CD44 shRNA/nanoparticles within cancer cells: perturbation of hyaluronan/CD44v6 interactions and reduction in adenoma growth in Apc Min/+ MICE. PMID: 19246453 Ref: Comparison of cyclooxygenase-2 and CD44 mRNA expression in colorectal cancer and its relevance for prognosis. PMID: 19277703 Ref: Expression of gastrin precursors by CD133-positive colorectal cancer cells is crucial for tumour growth. PMID: 19321126 Ref: Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. PMID: 19336570 Ref: Expression of standard CD44 in human colorectal carcinoma: association with prognosis. PMID: 19351367 Ref: Butyrate-induced alterations of phosphoinositide metabolism, protein kinase C activity and reduced CD44 variant expression in HT-29 colon cancer cells. PMID: 19360323 Ref: PCDH24-induced contact inhibition involves downregulation of beta-catenin signaling. PMID: 19383367 Ref: Cancer stem cell markers CD133 and CD24 correlate with invasiveness and differentiation in colorectal adenocarcinoma. PMID: 19437567 Ref: Phenotypic subpopulations of metastatic colon cancer stem cells: genomic analysis. PMID: 19451087 Ref: Combination of aging and dimethylhydrazine treatment causes an increase in cancer-stem cell population of rat colonic crypts. PMID: 19465005 Ref: Higher CO2-insufflation pressure inhibits the expression of adhesion molecules and the invasion potential of colon cancer cells. PMID: 19522021 Ref: [Galectin-9 isoforms influence the adhesion between colon carcinoma LoVo cells and human umbilical vein endothelial cells in vitro by regulating the expression of E-selectin in LoVo cells]. PMID: 19538882 Ref: Identification, characterization and utilization of tumor cell selectin ligands in the design of colon cancer diagnostics. PMID: 19581728 Ref: Newly characterised ex vivo colospheres as a three-dimensional colon cancer cell model of tumour aggressiveness. PMID: 19603013 Ref: Prognostic significance of the cancer stem cell markers CD133, CD44, and CD166 in colorectal cancer. PMID: 19626493 Ref: Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice. PMID: 19652364 Ref: Maintenance of HCT116 colon cancer cell line conforms to a stochastic model but not a cancer stem cell model. PMID: 19737148 Ref: BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells. PMID: 19738061 Ref: Frequent expression of the high molecular, 673-bp CD44v3,v8-10 variant in colorectal adenomas and carcinomas. PMID: 19787202 Ref: Depletion of the proteasome subunit PSMA7 inhibits colorectal cancer cell tumorigenicity and migration. PMID: 19787246 Ref: The Relationships Between Loss of Standard CD44 Expression and Lymph Node, Liver Metastasis in T3 Colorectal Carcinoma. PMID: 19937401 Ref: [Cultivation and characterization of tumor spheres generated from human colorectal cancer cell lines]. PMID: 19950614 Ref: Elimination of Colon Cancer Stem-Like Cells by the Combination of Curcumin and FOLFOX. PMID: 19956394 Ref: New Therapeutics Targeting Colon Cancer Stem Cells. PMID: 20148131 |
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