Primary Site >> Colorectal Cancer

Gene >> CD28

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Ref: A novel co-stimulatory T cell antigen co-expressed on renal cell carcinoma.
PMID: 7495750
Ref: Culture of tumour-infiltrating lymphocytes from melanoma and colon carcinoma: removal of tumour cells does not affect tumour-specificity.
PMID: 8536275
Ref: Treatment of heterotransplanted Hodgkin's tumors in SCID mice by a combination of human NK or T cells and bispecific antibodies.
PMID: 8581383
Ref: T-Cell co-stimulation by the CD28 ligand B7 is involved in the immune response leading to rejection of a spontaneously regressive tumor.
PMID: 8603819
Ref: The expression of costimulatory molecules CD80 and CD86 in human carcinoma cell lines: its regulation by interferon gamma and interleukin-10.
PMID: 9003466
Ref: Biologic properties of a bispecific single-chain antibody directed against 17-1A (EpCAM) and CD3: tumor cell-dependent T cell stimulation and cytotoxic activity.
PMID: 9103467
Ref: RP1, a new member of the adenomatous polyposis coli-binding EB1-like gene family, is differentially expressed in activated T cells.
PMID: 9233623
Ref: Construction and biological activity of a recombinant bispecific single-chain antibody designed for therapy of minimal residual colorectal cancer.
PMID: 9435872
Ref: [Overexpression of B7-1 amd B7-2 by LFA-1 positive lymphocytes in chronic inflammatory bowel diseases].
PMID: 14518246
Ref: Significance of pre-treatment immunological parameters in colorectal cancer patients with unresectable metastases to the liver.
PMID: 10228796
Ref: Carcinoembryonic antigen (CEA)-specific T-cell activation in colon carcinoma induced by anti-CD3 x anti-CEA bispecific diabodies and B7 x anti-CEA bispecific fusion proteins.
PMID: 10383154
Ref: Expression of CD28 and CD86 by human eosinophils and role in the secretion of type 1 cytokines (interleukin 2 and interferon gamma): inhibition by immunoglobulin a complexes.
PMID: 10449520
Ref: Expression of CD40 and its ligand, CD40L, in intestinal lesions of Crohn's disease.
PMID: 10566730
Ref: Modulation of CD4 cell cytokine production by colon cancer-associated mucin.
PMID: 10602890
Ref: Gr-1+ myeloid cells derived from tumor-bearing mice inhibit primary T cell activation induced through CD3/CD28 costimulation.
PMID: 10878351
Ref: Anti-Tumor CC49-zeta CD4 T cells possess both cytolytic and helper functions.
PMID: 11186154
Ref: Activated T lymphocytes bind in situ to stromal tissue of colon carcinoma but lack adhesion to tumor cells.
PMID: 11169447
Ref: Protective immunity against human carcinoembryonic antigen (CEA) induced by an oral DNA vaccine in CEA-transgenic mice.
PMID: 11300483
Ref: A dual-function DNA vaccine encoding carcinoembryonic antigen and CD40 ligand trimer induces T cell-mediated protective immunity against colon cancer in carcinoembryonic antigen-transgenic mice.
PMID: 11591784
Ref: Rejection of syngeneic colon carcinoma by CTLs expressing single-chain antibody receptors codelivering CD28 costimulation.
PMID: 12421958
Ref: [Determination of four kinds of cell phenotypes of peripheral blood lymphocytes in patients with colorectal cancer].
PMID: 12866971
Ref: [Expression of leucocyte cell-surface antigens on colon cancer cell line HR8348].
PMID: 15067730
Ref: Dendritic cells pulsed with an anti-idiotype antibody mimicking carcinoembryonic antigen (CEA) can reverse immunological tolerance to CEA and induce antitumor immunity in CEA transgenic mice.
PMID: 15256474
Ref: Effector memory T cells, early metastasis, and survival in colorectal cancer.
PMID: 16371631
Ref: A recombinant anti-carcinoembryonic antigen immunoreceptor with combined CD3zeta-CD28 signalling targets T cells from colorectal cancer patients against their tumour cells.
PMID: 16188919
Ref: Multiplex detection of surface molecules on colorectal cancers.
PMID: 16485257
Ref: Low surface expression of B7-1 (CD80) is an immunoescape mechanism of colon carcinoma.
PMID: 16489051
Ref: Antitumor activity of chimeric immunoreceptor gene-modified Tc1 and Th1 cells against autologous carcinoembryonic antigen-expressing colon cancer cells.
PMID: 16856879
Ref: Ex-vivo analysis of CD8+ T cells infiltrating colorectal tumors identifies a major effector-memory subset with low perforin content.
PMID: 16967323
Ref: Immune signatures of murine and human cancers reveal unique mechanisms of tumor escape and new targets for cancer immunotherapy.
PMID: 17606736
Ref: Investigation of CTLA-4 and CD28 gene polymorphisms in a group of Turkish patients with colorectal cancer.
PMID: 18680513
Ref: B7 blockade alters the balance between regulatory T cells and tumor-reactive T cells for immunotherapy of cancer.
PMID: 19188167
Ref: Peripheral blood gene expression of B7 and CD28 family members associated with tumor progression and microscopic lymphovascular invasion in colon cancer patients.
PMID: 20140740
Ref: Antisense anti IGF-I cellular therapy of malignant tumours: immune response in cancer patients.
PMID: 20630696
Ref: Novel role for STAT3 in transcriptional regulation of NK immune cell targeting receptor MICA on cancer cells.
PMID: 21257710
Ref: Improved activation toward primary colorectal cancer cells by antigen-specific targeting autologous cytokine-induced killer cells.
PMID: 22481963
Ref: [Differential analysis of lymphocyte subsets between colorectal carcinoma patients and healthy individuals].
PMID: 22768866
Ref: Role of macrophage migration inhibitory factor in the regulatory T cell response of tumor-bearing mice.
PMID: 22972922
Ref: The changes of Th17 cells and the related cytokines in the progression of human colorectal cancers.
PMID: 22994684
Ref: Functional analysis of B7-H3 in colonic carcinoma cells.
PMID: 23098490
Ref: Heteroclitic XBP1 peptides evoke tumor-specific memory cytotoxic T lymphocytes against breast cancer, colon cancer, and pancreatic cancer cells.
PMID: 25941601
Ref: Five functional polymorphisms of B7/CD28 co-signaling molecules alter susceptibility to colorectal cancer.
PMID: 25497975
Ref: CD80-CD28 signaling controls the progression of inflammatory colorectal carcinogenesis.
PMID: 25595911
Ref: Identification and Characterization of MEDI4736, an Antagonistic Anti-PD-L1 Monoclonal Antibody.
PMID: 25943534
Ref: IL-11 induces differentiation of myeloid-derived suppressor cells through activation of STAT3 signalling pathway.
PMID: 28781374
Ref: Expression of CD27, CD28 and IL-17A in peripheral blood from patients with colorectal carcinoma.
PMID: 26957265
Ref: Tumor-associated immune factors are associated with recurrence and metastasis in non-small cell lung cancer.
PMID: 28084319
Ref: Soluble CD80 Protein Delays Tumor Growth and Promotes Tumor-Infiltrating Lymphocytes.
PMID: 29122838
Ref: Polymorphisms in the ICOS/CD28-ICOSL pathway are related to capecitabine-based chemotherapy response in advanced colon cancer patients.
PMID: 29505962