Primary Site >> Colorectal Cancer

Gene >> CD247

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Ref: Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice.
PMID: 1465616
Ref: Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma.
PMID: 8242612
Ref: The decreased expression of CD3 zeta chains in cancer patients is not reversed by IL-2 administration.
PMID: 7989113
Ref: Alterations in the signal-transducing molecules of T cells and NK cells in colorectal tumor-infiltrating, gut mucosal and peripheral lymphocytes: correlation with the stage of the disease.
PMID: 7790109
Ref: Interleukin 2 restores CD3-zeta chain expression but fails to generate tumour-specific lytic activity in tumour-infiltrating lymphocytes derived from human colorectal hepatic metastases.
PMID: 9569042
Ref: A lack of evidence for down-modulation of CD3 zeta expression in colorectal carcinoma and pregnancy using multiple detection methods.
PMID: 10540179
Ref: An entirely humanized CD3 zeta-chain signaling receptor that directs peripheral blood t cells to specific lysis of carcinoembryonic antigen-positive tumor cells.
PMID: 10962448
Ref: Human natural killer cell line modified with a chimeric immunoglobulin T-cell receptor gene leads to tumor growth inhibition in vivo.
PMID: 11960290
Ref: Adverse immunoregulatory effects of 5FU and CPT11 chemotherapy on myeloid-derived suppressor cells and colorectal cancer outcomes.
PMID: 25209187
Ref: Immune response gene expression in colorectal cancer carries distinct prognostic implications according to tissue, stage and site: a prospective retrospective translational study in the context of a hellenic cooperative oncology group randomised trial.
PMID: 25970543
Ref: Impaired SNX9 Expression in Immune Cells during Chronic Inflammation: Prognostic and Diagnostic Implications.
PMID: 26608909
Ref: Effects of immuno-related gene polymorphisms on a bispecific antibody targeting colorectal cancer cell.
PMID: 29790821