Primary Site >> Liver Cancer

Gene >> CD1D

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Ref: CD1d-mediated stimulation of natural killer T cells selectively activates hepatic natural killer cells to eliminate experimentally disseminated hepatoma cells in murine liver.
PMID: 12794761
Ref: NKT cells from normal and tumor-bearing human livers are phenotypically and functionally distinct from murine NKT cells.
PMID: 12902477
Ref: In vivo priming of natural killer T cells by dendritic cells pulsed with hepatoma-derived acid-eluted substances.
PMID: 14624311
Ref: Production of profibrotic cytokines by invariant NKT cells characterizes cirrhosis progression in chronic viral hepatitis.
PMID: 15240738
Ref: Changes in natural killer T cells subsets during therapy in type C hepatitis and hepatocellular carcinoma.
PMID: 15905121
Ref: Glycolipids as immune modulatory tools.
PMID: 17100636
Ref: Enhanced antitumor response by divergent modulation of natural killer and natural killer T cells in the liver.
PMID: 17108139
Ref: Impairment of liver regeneration correlates with activated hepatic NKT cells in HBV transgenic mice.
PMID: 17523147
Ref: CD1d gene is a target for a novel amplicon at 1q22-23.1 in human hepatocellular carcinoma.
PMID: 19757161
Ref: Prolonged survival of human hepatocarcinoma cells in the liver of newborn C57BL/6 mice and resulting cellular xenorejection, especially the activation of hepatic natural killer T cells.
PMID: 20516727
Ref: NKT cell exacerbation of liver metastases arising from melanomas transplanted into either the eyes or spleens of mice.
PMID: 21330669
Ref: Circulating CD56dim natural killer cells and CD56+ T cells that produce interferon-gamma or interleukin-10 are expanded in asymptomatic, E antigen-negative patients with persistent hepatitis B virus infection.
PMID: 25186004
Ref: Tumor-induced CD11b(+) Gr-1(+) myeloid-derived suppressor cells exacerbate immune-mediated hepatitis in mice in a CD40-dependent manner.
PMID: 25616156
Ref: NKT cells in liver diseases.
PMID: 29623561
Ref: Elevated Hepatic CD1d Levels Coincide with Invariant NKT Cell Defects in Chronic Hepatitis B Virus Infection.
PMID: 29643189