Primary Site >> Colorectal Cancer

Gene >> CCR4

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Ref: Analysis of the transcription regulator, CNOT7, as a candidate chromosome 8 tumor suppressor gene in colorectal cancer.
PMID: 12845644
Ref: Selective infiltration of CCR5(+)CXCR3(+) T lymphocytes in human colorectal carcinoma.
PMID: 15856455
Ref: Increased expression of HSP70 by colon cancer cells is not always associated with access to the dendritic cell cross-presentation pathway.
PMID: 17235439
Ref: Quantification of the chemokines CCL17 and CCL22 in human colorectal adenocarcinomas.
PMID: 21479399
Ref: Anti-tumor effect of combining CC chemokine 22 and an anti-CD25 antibody on myeloma cells implanted subcutaneously into mice.
PMID: 21475900
Ref: Accumulation of CCR4(+)CTLA-4 FOXP3(+)CD25(hi) regulatory T cells in colon adenocarcinomas correlate to reduced activation of conventional T cells.
PMID: 22319577
Ref: CCR4 mediates CCL17 (TARC)-induced migration of human colon cancer cells via RhoA/Rho-kinase signaling.
PMID: 23649168
Ref: HMG-CoA reductase regulates CCL17-induced colon cancer cell migration via geranylgeranylation and RhoA activation.
PMID: 24582560
Ref: CCR4 C1014T and CCL22 C16A genetic variations in the Iranian patients with colorectal adenocarcinoma.
PMID: 25148803
Ref: IL-22 promotes the proliferation of cancer cells in smoking colorectal cancer patients.
PMID: 26293897
Ref: Feedback mechanisms between M2 macrophages and Th17 cells in colorectal cancer patients.
PMID: 27235120
Ref: CCR4 promotes metastasis via ERK/NF-kappaB/MMP13 pathway and acts downstream of TNF-alpha in colorectal cancer.
PMID: 27356745
Ref: [Phenotypic characteristics of LAP(+) CD4(+) T lymphocytes in colorectal cancer tissues].
PMID: 27531479
Ref: Role of LAP(+)CD4(+) T cells in the tumor microenvironment of colorectal cancer.
PMID: 28210081
Ref: Correction: CCR4 promotes metastasis via ERK/NF-kappaB/MMP13 pathway and acts downstream of TNF-alpha in colorectal cancer.
PMID: 28645139
Ref: Colorectal cancer-infiltrating T lymphocytes display a distinct chemokine receptor expression profile.
PMID: 29020986
Ref: Rapalog combined with CCR4 antagonist improves anticancer vaccines efficacy.
PMID: 30183073