Primary Site >> Stomach Cancer
Gene >> CCND1
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Amplified genes in cancer in upper digestive tract. PMID: 8095412 |
Ref: The 5D4 antibody (anti-cyclin D1/D2) related antigen: cytoplasmic staining is correlated to the progression of gastric cancer. PMID: 9778110 Ref: Expression of cyclin D1 and cyclin E in human gastric carcinoma and its clinicopathologic significance. PMID: 9811181 |
Ref: Expression of cell-cycle regulators, cyclin E and p21WAF1/CIP1, potential prognostic markers for gastric cancer. PMID: 10218458 Ref: Expression of p27Kip1 and cyclin D1 proteins is inversely correlated and is associated with poor clinical outcome in human gastric cancer. PMID: 10404130 Ref: Expression of cell-cycle regulatory proteins cyclin D1, cyclin E, and their inhibitor p21 WAF1/CIP1 in gastric cancer. PMID: 10547573 Ref: Cyclin D2, but not cyclin D1, overexpression closely correlates with gastric cancer progression and prognosis. PMID: 10547574 Ref: Evaluation of cyclin D1 mRNA expression in gastric and colorectal cancers. PMID: 10954128 Ref: Antisense to cyclin D1 reverses the transformed phenotype of human gastric cancer cells. PMID: 11819376 |
Ref: Cyclin D2 overexpression and lack of p27 correlate positively and cyclin E inversely with a poor prognosis in gastric cancer cases. PMID: 10666388 Ref: Immunohistochemical study on the expression of cyclin D1 and E in gastric cancer. PMID: 11059220 |
Ref: Cyclin D1 antisense oligonucleotide inhibits cell growth stimulated by epidermal growth factor and induces apoptosis of gastric cancer cells. PMID: 11676861 |
Ref: Contribution of cyclin d1 (CCND1) and E-cadherin (CDH1) polymorphisms to familial and sporadic colorectal cancer. PMID: 11896626 Ref: Expression of G1 phase cyclins in human gastric cancer and gastric mucosa of first-degree relatives. PMID: 12064799 Ref: Expression of cyclin genes in human gastric cancer and in first degree relatives. PMID: 12133540 |
Ref: Association of cyclin D1 (G870A) polymorphism with susceptibility to esophageal and gastric cardiac carcinoma in a northern Chinese population. PMID: 12673692 Ref: FLJ10261 gene, located within the CCND1-EMS1 locus on human chromosome 11q13, encodes the eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products. PMID: 12739008 Ref: [The association of cyclin D1 (A870G) polymorphism with susceptibility to esophageal and cardiac cancer in north Chinese population]. PMID: 12899785 Ref: Effects of cyclin D1 antisense oligodeoxyneucleotides on the growth and expression of G1 phase regulators in gastric carcinoma cells. PMID: 15015645 |
Ref: Nonsteroidal anti-inflammatory drug use associated with reduced incidence of adenocarcinomas of the esophagus and gastric cardia that overexpress cyclin D1: a population-based study. PMID: 14744730 Ref: Alteration of cyclin D1 in gastric carcinoma and its clinicopathologic significance. PMID: 15378768 |
Ref: beta-catenin (CTNNB1) gene amplification: a new mechanism of protein overexpression in cancer. PMID: 15609344 Ref: Recurrent chromosomal rearrangements at bands 8q24 and 11q13 in gastric cancer as detected by multicolor spectral karyotyping. PMID: 16127741 Ref: Polymorphism of p16 INK4A and cyclin D1 in adenocarcinomas of the upper gastrointestinal tract. PMID: 16163549 Ref: Cell-cycle regulators, bcl-2 and NF-kappaB in Epstein-Barr virus-positive gastric carcinomas. PMID: 16211221 |
Ref: Alterations of the CCND1 and HER-2/neu (ERBB2) proteins in esophageal and gastric cancers. PMID: 16490596 Ref: Cyclin D1 antisense oligodexoyneucleotides inhibits growth and enhances chemosensitivity in gastric carcinoma cells. PMID: 16586549 Ref: Characterizing genetically stable and unstable gastric cancers by microsatellites and array comparative genomic hybridization. PMID: 17011984 |
Ref: Conserved POU-binding site linked to SP1-binding site within FZD5 promoter: Transcriptional mechanisms of FZD5 in undifferentiated human ES cells, fetal liver/spleen, adult colon, pancreatic islet, and diffuse-type gastric cancer. PMID: 17273778 Ref: Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs. PMID: 17273804 Ref: Conserved POU/OCT- and GATA-binding sites in 5'-flanking promoter region of mammalian WNT8B orthologs. PMID: 17390031 Ref: Association of cyclin D1 G870A polymorphism with susceptibility to gastric cancers in Korean male patients. PMID: 17447856 Ref: Dysregulation of stem cell signaling network due to germline mutation, SNP, Helicobacter pylori infection, epigenetic change and genetic alteration in gastric cancer. PMID: 17568183 Ref: Cyclin D1 overexpression in N-methyl-N'-nitro-N-nitrosoguanidine-induced rat gastric adenocarcinomas. PMID: 17855062 |
Ref: Cyclin D1 expression is induced by viral BARF1 and is overexpressed in EBV-associated gastric cancer. PMID: 18437417 Ref: GG genotype of cyclin D1 G870A polymorphism is associated with non-cardiac gastric cancer in a high-risk region of China. PMID: 18609126 Ref: Integrative genomic analyses on GLI2: mechanism of Hedgehog priming through basal GLI2 expression, and interaction map of stem cell signaling network with P53. PMID: 18813803 |
Ref: Expression of retinoblastoma and cyclin D1 in gastric carcinoma. PMID: 19152247 Ref: Meta-analysis of genetic polymorphisms and gastric cancer risk: variability in associations according to race. PMID: 19375306 Ref: Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB. PMID: 19424592 Ref: Integrative genomic analyses on GLI1: positive regulation of GLI1 by Hedgehog-GLI, TGFbeta-Smads, and RTK-PI3K-AKT signals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals. PMID: 19513567 Ref: Arginine deiminase originating from Lactococcus lactis ssp. lactis American Type Culture Collection (ATCC) 7962 induces G1-phase cell-cycle arrest and apoptosis in SNU-1 stomach adenocarcinoma cells. PMID: 19624867 Ref: Association between cyclin D1 (CCND1) polymorphism and gastric cancer risk in Japanese population. PMID: 19760977 Ref: Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation. PMID: 19860666 Ref: [Relationship of the expression of cyclin D1 and P21WAF1 with the sensitivity to chemotherapeutic drugs on gastric cancers]. PMID: 19921577 Ref: Peripheral position of CCND1 and HER-2/neu oncogenes within chromosome territories in esophageal and gastric cancers non-related to amplification and overexpression. PMID: 21637674 |
Ref: Association between cyclin D1 polymorphism with CpG island promoter methylation status of tumor suppressor genes in gastric cancer. PMID: 20397048 Ref: Simvastatin inhibits cell growth and induces apoptosis and G0/G1 cell cycle arrest in hepatic cancer cells. PMID: 20878096 Ref: Epstein-Barr virus-specific methylation of human genes in gastric cancer cells. PMID: 21194482 |
Ref: Expression ratio of CCND1 to CDKN2A mRNA predicts RB1 status of cultured cancer cell lines and clinical tumor samples. PMID: 21447152 Ref: Cyclin D1 G870A polymorphism and breast cancer risk: a meta-analysis involving 23,998 subjects. PMID: 22812184 Ref: HSulf-1 suppresses cell growth and down-regulates Hedgehog signaling in human gastric cancer cells. PMID: 22848304 |
Ref: Prognostic value of oncoprotein expressions in thyroid papillary carcinoma. PMID: 21547408 Ref: First evidence that gamma-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-kappaB pathway. PMID: 22351692 Ref: Higher expression of the novel gene upregulated gene 4 in two acute lymphoblastic leukemia patients with poor prednisolone response. PMID: 22677619 |
Ref: microRNA-9 suppresses the proliferation, invasion and metastasis of gastric cancer cells through targeting cyclin D1 and Ets1. PMID: 23383271 Ref: The incidence and prognostic value of HER2 overexpression and cyclin D1 expression in patients with gastric or gastroesophageal junction adenocarcinoma in Israel. PMID: 23420289 Ref: Expression of C-X-C chemokine receptor types 1/2 in patients with gastric carcinoma: Clinicopathological correlations and significance. PMID: 23420470 Ref: SIRT1 is downregulated in gastric cancer and leads to G1-phase arrest via NF-kappaB/Cyclin D1 signaling. PMID: 24107295 Ref: Akt-p53-miR-365-cyclin D1/cdc25A axis contributes to gastric tumorigenesis induced by PTEN deficiency. PMID: 24149576 Ref: Transcriptomic changes induced by mycophenolic acid in gastric cancer cells. PMID: 24349619 |
Ref: Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products. PMID: 24233024 Ref: Intratumoral heterogeneous amplification of ERBB2 and subclonal genetic diversity in gastric cancers revealed by multiple ligation-dependent probe amplification and fluorescence in situ hybridization. PMID: 24491355 Ref: The significant association of CCND1 genotypes with gastric cancer in Taiwan. PMID: 25202078 Ref: Biphasic ER-alpha36-mediated estrogen signaling regulates growth of gastric cancer cells. PMID: 25231129 Ref: Correlation of RKIP, STAT3 and cyclin D1 expression in pathogenesis of gastric cancer. PMID: 25337233 |
Ref: Activation of beta-catenin signalling by TFF1 loss promotes cell proliferation and gastric tumorigenesis. PMID: 25107557 Ref: Heterogeneity of amplification of HER2, EGFR, CCND1 and MYC in gastric cancer. PMID: 25649416 Ref: Semi-comprehensive analysis of gene amplification in gastric cancers using multiplex ligation-dependent probe amplification and fluorescence in situ hybridization. PMID: 25743022 Ref: Antitumorigenic effect of plumbagin by induction of SH2-containing protein tyrosine phosphatase 1 in human gastric cancer cells. PMID: 25815436 Ref: Prospective comprehensive genomic profiling of advanced gastric carcinoma cases reveals frequent clinically relevant genomic alterations and new routes for targeted therapies. PMID: 25882375 Ref: Loss of TFF1 promotes Helicobacter pylori-induced beta-catenin activation and gastric tumorigenesis. PMID: 25980439 Ref: Epigenetic silencing of DUSP9 induces the proliferation of human gastric cancer by activating JNK signaling. PMID: 25998184 Ref: Downregulation of microRNA33a promotes cyclindependent kinase 6, cyclin D1 and PIM1 expression and gastric cancer cell proliferation. PMID: 26352175 Ref: [Effect of Jianpi Yangzheng Xiaozheng Recipe on Apoptosis and Autophagy of Subcutaneous Transplanted Tumor in Nude Mice: an Experimental Study on Mechanism]. PMID: 26591369 |
Ref: Cyclin D1 and cyclin E2 are differentially expressed in gastric cancer. PMID: 27034264 Ref: miR-935 promotes gastric cancer cell proliferation by targeting SOX7. PMID: 27044823 Ref: MicroRNA-193b inhibits the proliferation, migration and invasion of gastric cancer cells via targeting cyclin D1. PMID: 27071318 Ref: Association between cyclin D1 (CCND1) G870A polymorphism and gastric cancer risk: a meta-analysis. PMID: 27623072 Ref: Prognostic Importance of Cell Cycle Regulators Cyclin D1 (CCND1) and Cyclin-Dependent Kinase Inhibitor 1B (CDKN1B/p27) in Sporadic Gastric Cancers. PMID: 27781065 Ref: [Correlation analysis of G870A CCND1 gene polymorphism with digestive system tumors]. PMID: 27881356 |
Ref: Gene amplification of CCNE1, CCND1, and CDK6 in gastric cancers detected by multiplex ligation-dependent probe amplification and fluorescence in situ hybridization. PMID: 27864121 Ref: Rab14 Act as Oncogene and Induce Proliferation of Gastric Cancer Cells via AKT Signaling Pathway. PMID: 28107526 Ref: Effect of diterpenoid kaurenoic acid on genotoxicity and cell cycle progression in gastric cancer cell lines. PMID: 28273639 Ref: UBE2T knockdown inhibits gastric cancer progression. PMID: 28427240 Ref: Long noncoding RNA UCA1 induced by SP1 promotes cell proliferation via recruiting EZH2 and activating AKT pathway in gastric cancer. PMID: 28569779 Ref: Polymorphisms of microRNA target genes IL12B, INSR, CCND1 and IL10 in gastric cancer. PMID: 28596683 Ref: Cyclin D1 overexpression correlates with poor tumor differentiation and prognosis in gastric cancer. PMID: 28943959 Ref: The management of localized esophageal squamous cell carcinoma: Western approach. PMID: 29129086 Ref: LncRNA EGOT Promotes Tumorigenesis Via Hedgehog Pathway in Gastric Cancer. PMID: 29209988 Ref: HNRNPK inhibits gastric cancer cell proliferation through p53/p21/CCND1 pathway. PMID: 29262567 Ref: Constitutive activation of STAT3 and cyclin D1 overexpression contribute to proliferation, migration and invasion in gastric cancer cells. PMID: 29312519 |
Ref: MiR-22 sustains NLRP3 expression and attenuates H. pylori-induced gastric carcinogenesis. PMID: 29059152 Ref: microRNA-623 targets cyclin D1 to inhibit cell proliferation and enhance the chemosensitivity of cells to 5-fluorouracil in gastric cancer. PMID: 29495973 Ref: Prognostic Value of Cyclin D1 and CD44 Expression in Gastric Adenocarcinoma. PMID: 29497929 Ref: SOX2 inhibits cell proliferation and metastasis, promotes apoptotic by downregulating CCND1 and PARP in gastric cancer. PMID: 29511458 Ref: Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer. PMID: 29765046 Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 Ref: MiR-193a-5p and -3p Play a Distinct Role in Gastric Cancer: miR-193a-3p Suppresses Gastric Cancer Cell Growth by Targeting ETS1 and CCND1. PMID: 29848678 Ref: MicroRNA181a promotes cell proliferation and inhibits apoptosis in gastric cancer by targeting RASSF1A. PMID: 30106448 Ref: Extracellular acidity enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis via DR5 in gastric cancer cells. PMID: 30181698 |