Primary Site >> Esophagus Cancer
Gene >> CCND1
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Ref: Amplification and expression of the human cyclin D gene in esophageal cancer. PMID: 1533816 |
Ref: Amplification and overexpression of cyclin D1 in human hepatocellular carcinoma. PMID: 8240318 Ref: Altered expression of the cyclin D1 and retinoblastoma genes in human esophageal cancer. PMID: 8415648 |
Ref: Esophageal cancer. PMID: 7533069 Ref: Differential polymerase chain reaction assay of cyclin D1 gene amplification in esophageal carcinoma. PMID: 7866635 |
Ref: Antisense to cyclin D1 inhibits growth and reverses the transformed phenotype of human esophageal cancer cells. PMID: 7630641 Ref: Overexpression and localization of cyclin D1 mRNA and antigen in esophageal cancer. PMID: 7747810 |
Ref: [Analysis of the p16INK4, p15INK4B genes abnormality and the amplification of cyclin D1 gene in esophageal cancer]. PMID: 8920671 Ref: [Loss of CDKN2 gene and amplification of cyclin D1 gene in human esophageal cancer]. PMID: 9387288 Ref: [The expression of Rb, p16 and cyclin D1 in 41 esophageal cancers]. PMID: 9388858 |
Ref: Amplification and expression of the cyclin D1 gene in anal and esophageal squamous cell carcinomas. PMID: 9042789 Ref: Overexpression of cyclin D1 in rat esophageal carcinogenesis model. PMID: 9045891 Ref: Increased expression of the P27KIP1 protein in human esophageal cancer cell lines that over-express cyclin D1. PMID: 9214595 |
Ref: Amplification and overexpression of cyclin D1 in aggressive human esophageal cancer. PMID: 9458316 Ref: Effect of cyclin D1 and associated proteins on proliferation of esophageal squamous cell carcinoma. PMID: 9683778 Ref: Quantitative analysis of the cyclin expression in human esophageal cancer cell lines. PMID: 10089073 Ref: [Effect of cyclin D1 protein expression on the prognosis of esophageal squamous-cell carcinoma treated with preoperative radiotherapy]. PMID: 10920963 |
Ref: Prognostic significance of cyclin D1 in esophageal squamous cell carcinoma patients treated with surgery alone or combined therapy modalities. PMID: 9988238 Ref: p53, p21(Waf1/Cip1) and cyclin D1 protein expression and prognosis in esophageal cancer. PMID: 10466043 Ref: A significant morphological transformation is recognized in human esophageal cancer cells with an amplification/overexpression of the cyclin D1 gene. PMID: 10568815 |
Ref: Cyclin D1 expression is useful as a prognostic indicator for advanced esophageal carcinomas, but not for superficial tumors. PMID: 10795746 Ref: Early deregulation of the the p16ink4a-cyclin D1/cyclin-dependent kinase 4-retinoblastoma pathway in cell proliferation-driven esophageal tumorigenesis in zinc-deficient rats. PMID: 10969811 |
Ref: Insufficient effect of p27(KIP1) to inhibit cyclin D1 in human esophageal cancer in vitro. PMID: 11115553 Ref: Expression of cyclin D1 and p53 and its correlation with proliferative activity in the spectrum of esophageal carcinomas induced after duodenal content reflux and 2,6-dimethylnitrosomorpholine administration in rats. PMID: 11181448 Ref: Alterations in cyclin D1 expression in esophageal squamous cell carcinoma in the Indian population. PMID: 11315260 Ref: Cyclin D1 overexpression as a prognostic factor in patients with esophageal carcinoma. PMID: 11745809 |
Ref: A multi-institutional study of immunohistochemical investigation for the roles of cyclin D1 and E-cadherin in superficial squamous cell carcinoma of the esophagus. PMID: 11870667 Ref: Overexpression of cyclin DI contributes to malignant properties of esophageal tumor cells by increasing VEGF production and decreasing Fas expression. PMID: 12014632 |
Ref: FLJ10261 gene, located within the CCND1-EMS1 locus on human chromosome 11q13, encodes the eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products. PMID: 12739008 Ref: Evolutionary conservation of CCND1-ORAOV1-FGF19-FGF4 locus from zebrafish to human. PMID: 12792807 Ref: Genetic polymorphisms and susceptibility to esophageal cancer among Chinese population (review). PMID: 12883749 Ref: [The association of cyclin D1 (A870G) polymorphism with susceptibility to esophageal and cardiac cancer in north Chinese population]. PMID: 12899785 Ref: An alternatively spliced cyclin D1 isoform, cyclin D1b, is a nuclear oncogene. PMID: 14612495 |
Ref: Cytogenetic alterations in chagasic achalasia compared to esophageal carcinoma. PMID: 15104278 Ref: Prognostic and clinicopathological features of E-cadherin, alpha-catenin, beta-catenin, gamma-catenin and cyclin D1 expression in human esophageal squamous cell carcinoma. PMID: 15484291 Ref: Flavopiridol as a radio-sensitizer for esophageal cancer cell lines. PMID: 15569374 Ref: [Flow cytometric detection and significance of four cyclins in esophageal cancer]. PMID: 15634523 |
Ref: A mouse model of oral-esophageal carcinogenesis. PMID: 15696643 Ref: Comparative genomics on mammalian Fgf3-Fgf4 locus. PMID: 15942670 Ref: Polymorphism of p16 INK4A and cyclin D1 in adenocarcinomas of the upper gastrointestinal tract. PMID: 16163549 Ref: Alterations of p53, cyclin D1 and pRB expression in the carcinogenesis of esophageal squamous cell carcinoma. PMID: 16273238 |
Ref: Cyclin D1 overexpression in esophageal cancer from southern China and its clinical significance. PMID: 16051426 Ref: Alterations of the CCND1 and HER-2/neu (ERBB2) proteins in esophageal and gastric cancers. PMID: 16490596 Ref: Identification of mutations that disrupt phosphorylation-dependent nuclear export of cyclin D1. PMID: 16732330 |
Ref: Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs. PMID: 17273804 Ref: Role of BCL2 (ala43thr), CCND1 (G870A) and FAS (A-670G) polymorphisms in modulating the risk of developing esophageal cancer. PMID: 17561354 Ref: Influence of apoptosis (BCL2, FAS), cell cycle (CCND1) and growth factor (EGF, EGFR) genetic polymorphisms on survival outcome: an exploratory study in squamous cell esophageal cancer. PMID: 17912028 |
Ref: Genomic profiling of 766 cancer-related genes in archived esophageal normal and carcinoma tissues. PMID: 18241037 Ref: Effects of Oxymatrine on the apoptosis of human esophageal carcinoma Eca109 cell line and its mechanism. PMID: 18563331 |
Ref: Overexpression of degenerative spermatocyte homolog 1 up-regulates the expression of cyclin D1 and enhances metastatic efficiency in esophageal carcinoma Eca109 cells. PMID: 19263436 Ref: Targets for molecular therapy in esophageal squamous cell carcinoma: an immunohistochemical analysis. PMID: 19302210 Ref: Integrative genomic analyses on GLI1: positive regulation of GLI1 by Hedgehog-GLI, TGFbeta-Smads, and RTK-PI3K-AKT signals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals. PMID: 19513567 Ref: Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation. PMID: 19860666 Ref: Peripheral position of CCND1 and HER-2/neu oncogenes within chromosome territories in esophageal and gastric cancers non-related to amplification and overexpression. PMID: 21637674 |
Ref: Genetic alterations in a telomerase-immortalized human esophageal epithelial cell line: implications for carcinogenesis. PMID: 20092939 Ref: Esophageal cancer-related gene 4 is a secreted inducer of cell senescence expressed by aged CNS precursor cells. PMID: 20404145 |
Ref: Phosphorylation-dependent regulation of SCF(Fbx4) dimerization and activity involves a novel component, 14-3-3varepsilon. PMID: 21242966 Ref: Genomic imbalances in esophageal carcinoma cell lines involve Wnt pathway genes. PMID: 21734802 Ref: Impaired nuclear export of tumor-derived c-terminal truncated cyclin D1 mutant in ESCC cancer. PMID: 22848289 |
Ref: Prognostic significance of cyclinD1 amplification and the co-alteration of cyclinD1/pRb/ppRb in patients with esophageal squamous cell carcinoma. PMID: 22150974 Ref: Genome-wide screening for genetic alterations in esophageal cancer by aCGH identifies 11q13 amplification oncogenes associated with nodal metastasis. PMID: 22761904 Ref: Cyclin D1 G870A polymorphism is a risk factor for esophageal cancer among Asians. PMID: 23020291 |
Ref: Lack of association between Cyclin D1 gene G870A polymorphism and esophageal cancer: evidence from a meta-analysis. PMID: 23661400 Ref: The determination of genetic markers of age-related cancer pathologies in populations from Kazakhstan. PMID: 23675381 Ref: The radiation-sensitizing effect of flavopiridol in the esophageal cancer cell line Eca109. PMID: 23833659 Ref: Effect of STAT5 silenced by siRNA on proliferation apoptosis and invasion of esophageal carcinoma cell line Eca-109. PMID: 23915238 Ref: Primary mucosa-associated lymphoid tissue lymphoma of the esophagus, manifesting as a submucosal tumor. PMID: 23981946 Ref: Genetic polymorphism of CCND1 G870A and esophageal cancer susceptibility: A meta-analysis. PMID: 24648939 |
Ref: CCND1 G870A polymorphism contributes to the risk of esophageal cancer: An updated systematic review and cumulative meta-analysis. PMID: 24944806 Ref: Transcription factor OCT4 promotes cell cycle progression by regulating CCND1 expression in esophageal carcinoma. PMID: 25128069 |
Ref: A systematic review and meta-analysis of somatic and germline DNA sequence biomarkers of esophageal cancer survival, therapy response and stage. PMID: 25214541 Ref: Marsdenia tenacissima extract induces G0/G1 cell cycle arrest in human esophageal carcinoma cells by inhibiting mitogen-activated protein kinase (MAPK) signaling pathway. PMID: 26073339 |
Ref: Inhibition of cyclin D1 enhances sensitivity to radiotherapy and reverses epithelial to mesenchymal transition for esophageal cancer cells. PMID: 26561473 Ref: Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population. PMID: 26873401 Ref: Downregulation of Ubiquitin-conjugating Enzyme UBE2D3 Promotes Telomere Maintenance and Radioresistance of Eca-109 Human Esophageal Carcinoma Cells. PMID: 27326259 Ref: A study of CCND1 with epithelial ovarian cancer cell proliferation and apoptosis. PMID: 27831653 |
Ref: Accumulated promoter methylation as a potential biomarker for esophageal cancer. PMID: 27893424 Ref: MicroRNAs in esophageal squamous cell carcinoma: Potential biomarkers and therapeutic targets. PMID: 28269750 Ref: Genetic Alterations in Esophageal Tissues From Squamous Dysplasia to Carcinoma. PMID: 28365443 Ref: Functional evidence that the self-renewal gene NANOG regulates esophageal squamous cancer development. PMID: 28601640 Ref: ABT-263 induces G1/G0-phase arrest, apoptosis and autophagy in human esophageal cancer cells in vitro. PMID: 28713162 Ref: The management of localized esophageal squamous cell carcinoma: Western approach. PMID: 29129086 |
Ref: An In vitro Study on Curcumin Delivery by Nano-Micelles for Esophageal Squamous Cell Carcinoma (KYSE-30). PMID: 29765996 |