Primary Site >> Colorectal Cancer
Gene >> CCND1
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Ref: Amplification of cyclin genes in colorectal carcinomas. PMID: 8481900 |
Ref: Esophageal cancer. PMID: 7533069 Ref: The PRAD-1/cyclin D1 oncogene product accumulates aberrantly in a subset of colorectal carcinomas. PMID: 8056453 |
Ref: Cyclin D1 oncoprotein aberrantly accumulates in malignancies of diverse histogenesis. PMID: 7862456 |
Ref: Prognostic significance of CCND1 (cyclin D1) overexpression in primary resected non-small-cell lung cancer. PMID: 8562333 Ref: Different expression patterns of cyclins A, D1 and E in human colorectal cancer. PMID: 8576279 Ref: Increased expression of cyclin D1 is an early event in multistage colorectal carcinogenesis. PMID: 8608874 Ref: [Cyclin D, CDK4 and p16 expression in colorectal cancer]. PMID: 8920673 |
Ref: Antisense to cyclin D1 inhibits the growth and tumorigenicity of human colon cancer cells. PMID: 9108461 Ref: [Malignancy of colorectal cancer analyzed by expression of cyclin D1]. PMID: 9263512 Ref: Expression of cyclins D1 and E in human colon adenocarcinomas. PMID: 9604788 |
Ref: Mechanism of cyclin D1 (CCND1, PRAD1) overexpression in human cancer cells: analysis of allele-specific expression. PMID: 9591636 Ref: Short-chain fatty acids inhibit intestinal trefoil factor gene expression in colon cancer cells. PMID: 9655688 Ref: Expression of cyclin D1 and retinoblastoma protein in colorectal cancer. PMID: 9893631 |
Ref: Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. PMID: 10201372 Ref: The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. PMID: 10318916 Ref: NA22598, a novel antitumor compound, reduces cyclin D1 levels, arrests cell cycle at G1 phase, and inhibits anchorage-independent growth of human tumor cells. PMID: 10366423 Ref: Expression of cell cycle markers in colorectal carcinoma: superiority of cyclin A as an indicator of poor prognosis. PMID: 10371338 Ref: Assessment of biomarkers in paired primary and recurrent colorectal adenocarcinomas. PMID: 10613309 Ref: Evaluation of cyclin D1 mRNA expression in gastric and colorectal cancers. PMID: 10954128 |
Ref: Effects of cyclin D1 polymorphism on age of onset of hereditary nonpolyposis colorectal cancer. PMID: 10667569 Ref: Overexpression of cyclin D1 mRNA in colorectal carcinomas and relationship to clinicopathological features: an in situ hybridization analysis. PMID: 10749591 Ref: Protein expression of p53, p21 (WAF1/CIP1), bcl-2, Bax, cyclin D1 and pRb in human colon carcinomas. PMID: 10782880 Ref: Gut-enriched Kruppel-like factor represses cyclin D1 promoter activity through Sp1 motif. PMID: 10908361 Ref: Cyclin D1 protein expression and gene polymorphism in colorectal cancer. Aberdeen Colorectal Initiative. PMID: 10964085 Ref: Human colorectal cancers with an intact p16/cyclin D1/pRb pathway have up-regulated p16 expression and decreased proliferation in small invasive tumor clusters. PMID: 11106567 Ref: Overexpression of cyclin D1 and cyclin E in 1,2-dimethylhydrazine dihydrochloride-induced rat colon carcinogenesis. PMID: 14614307 |
Ref: Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer. PMID: 11326276 Ref: Molecular markers are predictors of recurrence and survival in patients with Dukes B and Dukes C colorectal adenocarcinoma. PMID: 11330579 Ref: Doxorubicin bound to a HPMA copolymer carrier through hydrazone bond is effective also in a cancer cell line with a limited content of lysosomes. PMID: 11489498 Ref: CYCLIN D1 as a genetic modifier in hereditary nonpolyposis colorectal cancer. PMID: 11507050 Ref: Correlation of beta-catenin and cyclin D1 expression in colon cancers. PMID: 11574779 |
Ref: p53 inhibits adriamycin-induced down-regulation of cyclin D1 expression in human cancer cells. PMID: 11798189 Ref: Contribution of cyclin d1 (CCND1) and E-cadherin (CDH1) polymorphisms to familial and sporadic colorectal cancer. PMID: 11896626 Ref: Role of beta-catenin/T-cell factor-regulated genes in ovarian endometrioid adenocarcinomas. PMID: 11943708 Ref: Cyclin D1 overexpression in colorectal carcinoma in vivo is dependent on beta-catenin protein dysregulation, but not k-ras mutation. PMID: 12081197 Ref: Cyclin D1 and cyclin E are co-localized with cyclo-oxygenase 2 (COX-2) in pyramidal neurons in Alzheimer disease temporal cortex. PMID: 12152783 Ref: Fighting colorectal cancer: molecular epidemiology differences among Ashkenazi and Sephardic Jews and Palestinians. PMID: 12196377 Ref: Altered expression of beta-catenin during radiation-induced colonic carcinogenesis. PMID: 12530573 |
Ref: Oncogenic transformation of normal enterocytes by overexpression of cyclin D1. PMID: 12870780 Ref: Cyclin D1 expression in the intestinal mucosa and tumors of Apc1638N mice. PMID: 12894495 Ref: Beta-catenin/Tcf-1-mediated transactivation of cyclin D1 promoter is negatively regulated by thyroid hormone. PMID: 12951064 Ref: Cdx1 inhibits the proliferation of human colon cancer cells by reducing cyclin D1 gene expression. PMID: 14508520 Ref: [Relationship of Stat3 and its target gene products with malignancy in human colorectal carcinoma]. PMID: 14613639 Ref: Association of the cyclin D1 A870G polymorphism with advanced colorectal cancer. PMID: 14657069 Ref: Lack of association between CCND1 G870A polymorphism and the risk of breast and colorectal cancers. PMID: 14666635 |
Ref: Beta-catenin and cyclin D1: connecting development to breast cancer. PMID: 14712077 Ref: Immunohistochemical expression of cyclin D1, cyclin E, p21/waf1 and p27/kip1 in inflammatory bowel disease: correlation with other cell-cycle-related proteins (Rb, p53, ki-67 and PCNA) and clinicopathological features. PMID: 15060836 Ref: CCND1 polymorphism and age of onset of hepatoblastoma. PMID: 15133490 Ref: Constitutive activation of Stat3 signaling pathway in human colorectal carcinoma. PMID: 15162527 Ref: Expression patterns of cell cycle and apoptosis-related genes in a multidrug-resistant human colon carcinoma cell line. PMID: 15180185 Ref: Cdx1 inhibits human colon cancer cell proliferation by reducing beta-catenin/T-cell factor transcriptional activity. PMID: 15215241 Ref: Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice. PMID: 15314168 Ref: Minireview: Cyclin D1: normal and abnormal functions. PMID: 15331580 Ref: Cyclin A and cyclin D1 as significant prognostic markers in colorectal cancer patients. PMID: 15385053 Ref: Tissue microarray analysis of cyclin D1 gene amplification and gain in colorectal carcinomas. PMID: 15557752 Ref: Conjugated docosahexaenoic acid is a potent inducer of cell cycle arrest and apoptosis and inhibits growth of colo 201 human colon cancer cells. PMID: 15572300 |
Ref: Activation of PPAR{gamma} by curcumin inhibits Moser cell growth and mediates suppression of gene expression of cyclin D1 and EGFR. PMID: 15486348 Ref: Expression and gene amplification of primary (A, B1, D1, D3, and E) and secondary (C and H) cyclins in colon adenocarcinomas and correlation with patient outcome. PMID: 15858123 Ref: GG genotype of cyclin D1 G870A polymorphism is associated with increased risk and advanced colorectal cancer in patients in Singapore. PMID: 15862753 Ref: Cyclin D1 protein and CCND1 gene expression in colorectal cancer. PMID: 15993030 Ref: Nuclear beta-catenin expression is rare and its potential association with short survival in colorectal signet-ring cell carcinoma. PMID: 16082250 Ref: Tumor-targeting peptide-PNA-peptide chimeras for imaging overexpressed oncogene mRNAs. PMID: 16248097 Ref: The significance of tumor markers for proliferation and apoptosis in predicting survival in colorectal cancer. PMID: 16400510 Ref: Correlation between the expressions of gastrin, somatostatin and cyclin and cyclin-depend kinase in colorectal cancer. PMID: 16437675 Ref: [Clinical significance of cyclin Dl expression in non-small cell lung cancer]. PMID: 16989170 |
Ref: Elevated risk of colorectal cancer associated with the AA genotype of the cyclin D1 A870G polymorphism in an Indian population. PMID: 16328437 Ref: Cyclin D1 and Rb protein expression and their correlation with prognosis in patients with colon cancer. PMID: 16426443 Ref: 9-Hydroxystearic acid interferes with EGF signalling in a human colon adenocarcinoma. PMID: 16487928 Ref: Cyclin D1 A870G polymorphism and the risk of colorectal cancer and adenoma. PMID: 16495921 Ref: Impact of the cyclin D1 A870G polymorphism on susceptibility to sporadic colorectal cancer in Taiwan. PMID: 16552496 Ref: High-resolution analysis of chromosome rearrangements on 8p in breast, colon and pancreatic cancer reveals a complex pattern of loss, gain and translocation. PMID: 16636668 Ref: Cyclin D1 and epidermal growth factor polymorphisms associated with survival in patients with advanced colorectal cancer treated with Cetuximab. PMID: 16788380 Ref: The effect of the cyclin D1 (CCND1) A870G polymorphism on colorectal cancer risk is modified by glutathione-S-transferase polymorphisms and isothiocyanate intake in the Singapore Chinese Health Study. PMID: 16829689 |
Ref: HER2, TOP2A, CCND1, EGFR and C-MYC oncogene amplification in colorectal cancer. PMID: 16882699 Ref: Requirement of Pygopus 2 in breast cancer. PMID: 17203217 Ref: STAT3 mRNA and protein expression in colorectal cancer: effects on STAT3-inducible targets linked to cell survival and proliferation. PMID: 17264243 Ref: Celecoxib inhibits the expression of survivin via the suppression of promoter activity in human colon cancer cells. PMID: 17270149 Ref: Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs. PMID: 17273804 Ref: Survey of molecular profiling during human colon cancer development and progression by immunohistochemical staining on tissue microarray. PMID: 17278192 Ref: Activation of tumor-specific splice variant Rac1b by dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells. PMID: 17363564 Ref: Conserved POU/OCT- and GATA-binding sites in 5'-flanking promoter region of mammalian WNT8B orthologs. PMID: 17390031 Ref: Cyclin D1 gene G870A polymorphism predicts response to neoadjuvant radiotherapy and prognosis in rectal cancer. PMID: 17398034 Ref: The growth-inhibitory effects of tomatoes digested in vitro in colon adenocarcinoma cells occur through down regulation of cyclin D1, Bcl-2 and Bcl-xL. PMID: 17490506 Ref: ARA54 is involved in transcriptional regulation of the cyclin D1 gene in human cancer cells. PMID: 17510080 Ref: Green tea selectively targets initial stages of intestinal carcinogenesis in the AOM-ApcMin mouse model. PMID: 17638923 Ref: Adiposity-related protection of intestinal tumorigenesis: interaction with dietary calcium. PMID: 17640161 Ref: Apoptosis, cell cycle progression and gene expression in TP53-depleted HCT116 colon cancer cells in response to short-term 5-fluorouracil treatment. PMID: 17982676 Ref: Predictive molecular markers for colorectal cancer patients with resected liver metastasis and adjuvant chemotherapy. PMID: 18054556 |
Ref: Association of familial colorectal cancer with variants in the E-cadherin (CDH1) and cyclin D1 (CCND1) genes. PMID: 17960397 Ref: Aurora-A and Cyclin D1 polymorphisms and the age of onset of colorectal cancer in hereditary nonpolyposis colorectal cancer. PMID: 18027856 Ref: The association of cyclin D1 G870A and E-cadherin C-160A polymorphisms with the risk of colorectal cancer in a case control study and meta-analysis. PMID: 18196581 Ref: Influence of cancer-related gene polymorphisms on clinicopathological features in colorectal cancer. PMID: 18205772 Ref: Cyclin D1 expression in breast cancer patients receiving adjuvant tamoxifen-based therapy. PMID: 18347178 Ref: Metformin suppresses intestinal polyp growth in ApcMin/+ mice. PMID: 18803638 Ref: The influence of the Cyclin D1 870 G>A polymorphism as an endometrial cancer risk factor. PMID: 18822177 Ref: Cyclin D1 Pro241Pro (CCND1-G870A) polymorphism is associated with increased cancer risk in human populations: a meta-analysis. PMID: 18843022 Ref: Cyclin D1-specific cytotoxic T lymphocytes are present in the repertoire of cancer patients: implications for cancer immunotherapy. PMID: 18927298 Ref: Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype. PMID: 18983468 Ref: Cyclin D1 A870G polymorphism in Brazilian colorectal cancer patients. PMID: 19373442 Ref: p16, cyclin D1 and Rb expression in colorectal carcinomas: Correlations with clinico-pathological parameters and prognosis. PMID: 21479373 |
Ref: PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1. PMID: 19232344 Ref: Factors influencing histological response after neoadjuvant chemoradiation therapy for rectal carcinoma. PMID: 19446404 Ref: NGX6 inhibits AP-1 and Ets-1 expression and down-regulates cyclin D1 in human colorectal cancer. PMID: 19499154 Ref: A cohort study of cyclin D1 expression and prognosis in 602 colon cancer cases. PMID: 19549773 Ref: Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model. PMID: 19623659 Ref: Genetic variants in the cell cycle control pathways contribute to early onset colorectal cancer in Lynch syndrome. PMID: 19690970 Ref: Epidermal growth factor receptor is required for colonic tumor promotion by dietary fat in the azoxymethane/dextran sulfate sodium model: roles of transforming growth factor-{alpha} and PTGS2. PMID: 19903783 Ref: Factors influencing prognosis after neo-adjuvant chemoradiation therapy for rectal carcinoma. PMID: 19943591 |
Ref: Expression of cyclin D2 is an independent predictor of the development of hepatic metastasis in colorectal cancer. PMID: 19508551 Ref: Association of selected polymorphisms of CCND1, p21, and caspase8 with colorectal cancer risk. PMID: 19795398 Ref: Modulation of stress genes expression profile by nitric oxide-releasing aspirin in Jurkat T leukemia cells. PMID: 20188076 Ref: An alternative cyclin-D1 splice site is not linked to inflammatory bowel disease-associated neoplasia. PMID: 20306448 Ref: MUC1 regulates nuclear localization and function of the epidermal growth factor receptor. PMID: 20406885 Ref: Lignans inhibit cell growth via regulation of Wnt/beta-catenin signaling. PMID: 20510325 Ref: [Effects of perioperative total parenteral nutrition support on cyclin D1 expression, recurrence and metastasis of colorectal cancer cells]. PMID: 20577923 Ref: The influence of cyclin D1 A870G polymorphism on colorectal cancer risk and prognosis in a Turkish population. PMID: 20683026 Ref: Association between single-nucleotide polymorphisms of selected genes involved in the response to DNA damage and risk of colon, head and neck, and breast cancers in a Polish population. PMID: 20720310 Ref: Curcumin in cancer chemoprevention: molecular targets, pharmacokinetics, bioavailability, and clinical trials. PMID: 20726007 Ref: [Effect of COX-2 inhibitor on the expression of BCL-3 and cyclin D1 in human colon cancer cell line SW480]. PMID: 20737317 Ref: Pleurotus ostreatus inhibits colitis-related colon carcinogenesis in mice. PMID: 20878085 Ref: Alternative cyclin D1 splice forms differentially regulate the DNA damage response. PMID: 20940395 |
Ref: Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review. PMID: 20473920 Ref: NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). PMID: 20715105 Ref: Expression of phosphorylated Stat5 predicts expression of cyclin D1 and correlates with poor prognosis of colonic adenocarcinoma. PMID: 21079973 Ref: Rapid induction of colon carcinogenesis in CYP1A-humanized mice by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate. PMID: 21081470 Ref: Cyclin D1 rare variants in UK multiple adenoma and early-onset colorectal cancer patients. PMID: 21107342 Ref: Impact of cell-proliferation-associated gene expression on 2-deoxy-2-[(18)f]fluoro-D-glucose (FDG) kinetics as measured by dynamic positron emission tomography (dPET) in colorectal tumors. PMID: 21153447 Ref: Ibuprofen inhibits activation of nuclear {beta}-catenin in human colon adenomas and induces the phosphorylation of GSK-3{beta}. PMID: 21205744 Ref: Ganodermanontriol, a lanostanoid triterpene from Ganoderma lucidum, suppresses growth of colon cancer cells through ss-catenin signaling. PMID: 21225227 Ref: The dual EGFR/HER2 inhibitor lapatinib synergistically enhances the antitumor activity of the histone deacetylase inhibitor panobinostat in colorectal cancer models. PMID: 21464044 Ref: The cyclin D1 G870A polymorphism and colorectal cancer susceptibility: a meta-analysis of 20 populations. PMID: 21517236 Ref: Monoacylglycerol lipase (MAGL) knockdown inhibits tumor cells growth in colorectal cancer. PMID: 21543155 Ref: Cyclin D1 G870A polymorphism and colorectal cancer susceptibility: a meta-analysis of 20 populations. PMID: 21544737 Ref: Evaluation of the effects of the flavonoid apigenin on apoptotic pathway gene expression on the colon cancer cell line (HT29). PMID: 21548803 Ref: Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/beta-catenin/cyclin D1 signaling pathway in rats. PMID: 21764859 Ref: Cyclin D1 expression in colorectal cancer is a favorable prognostic factor in men but not in women in a prospective, population-based cohort study. PMID: 21888663 Ref: Pharmacogenetic profiling and cetuximab outcome in patients with advanced colorectal cancer. PMID: 22117530 |
Ref: Cyclin D1 (CCND1) G870A gene polymorphism is an ethnicity-dependent risk factor for digestive tract cancers: a meta-analysis comprising 20,271 subjects. PMID: 21606015 Ref: Boswellic acid inhibits growth and metastasis of human colorectal cancer in orthotopic mouse model by downregulating inflammatory, proliferative, invasive and angiogenic biomarkers. PMID: 21702037 Ref: A high-fat diet increases angiogenesis, solid tumor growth, and lung metastasis of CT26 colon cancer cells in obesity-resistant BALB/c mice. PMID: 21919080 Ref: An integrated genomic approach to identify predictive biomarkers of response to the aurora kinase inhibitor PF-03814735. PMID: 22222631 Ref: Strand-specific miR-28-5p and miR-28-3p have distinct effects in colorectal cancer cells. PMID: 22240480 Ref: CCND1 G870A polymorphism is associated with increased risk of colorectal cancer, especially for sporadic colorectal cancer and in Caucasians: a meta-analysis. PMID: 22322158 Ref: [Long non-coding RNA influences radiosensitivity of colorectal carcinoma cell lines by regulating cyclin D1 expression]. PMID: 22454180 Ref: Cyclin D1 G870A polymorphism contributes to colorectal cancer susceptibility: evidence from a systematic review of 22 case-control studies. PMID: 22606291 Ref: Both stromal cell and colonocyte epidermal growth factor receptors control HCT116 colon cancer cell growth in tumor xenografts. PMID: 22791816 Ref: Phosphoinositide-3-kinase, catalytic, alpha polypeptide RNA interference inhibits growth of colon cancer cell SW948. PMID: 22807617 Ref: Thymidylate synthase and cyclin D1 protein expression in lymph node negative colorectal cancer: role as prognostic factors? PMID: 22819905 Ref: A comprehensive characterization of genome-wide copy number aberrations in colorectal cancer reveals novel oncogenes and patterns of alterations. PMID: 22860045 Ref: Expression of Cyclin D1 Is Associated with beta-Catenin Expression and Correlates with Good Prognosis in Colorectal Adenocarcinoma. PMID: 23066445 Ref: Expression of cyclin D1a and D1b as predictive factors for treatment response in colorectal cancer. PMID: 23099809 |
Ref: Co-existence of cyclin D1 and vascular endothelial growth factor protein expression is a poor prognostic factor for UICC stage I-III colorectal cancer patients after curative resection. PMID: 22926658 Ref: Expression of the MAP kinase phosphatase DUSP4 is associated with microsatellite instability in colorectal cancer (CRC) and causes increased cell proliferation. PMID: 22965873 Ref: Protocatechualdehyde possesses anti-cancer activity through downregulating cyclin D1 and HDAC2 in human colorectal cancer cells. PMID: 23159608 Ref: Systematic review: diet-gene interactions and the risk of colorectal cancer. PMID: 23216531 Ref: Assessment of Cryptosporidium parvum infection in immunocompetent and immunocompromised mice and its role in triggering intestinal dysplasia. PMID: 23291034 Ref: Cyclin D1 G870A polymorphism and risk of colorectal cancer: a case control study. PMID: 23354584 Ref: Genotyping by induced Forster Resonance Energy Transfer(iFRET) mechanism and simultaneous mutation scanning. PMID: 23520118 Ref: Gankyrin activates IL-8 to promote hepatic metastasis of colorectal cancer. PMID: 23576566 Ref: miR-449b inhibits the proliferation of SW1116 colon cancer stem cells through downregulation of CCND1 and E2F3 expression. PMID: 23674142 Ref: Chemoprevention of colon and small intestinal tumorigenesis in APC(min/+) mice by SHetA2 (NSC721689) without toxicity. PMID: 23852423 Ref: [Impact of CCND1 A870G polymorphism on acute adverse events in postoperative rectal cancer patients treated with adjuvant concurrent chemoradiotherapy]. PMID: 23985254 Ref: Sporadic colorectal cancer development shows rejuvenescence regarding epithelial proliferation and apoptosis. PMID: 24098334 Ref: The prognostic significance of WNT pathway in surgically-treated colorectal cancer: beta-catenin expression predicts for disease-free survival. PMID: 24123033 Ref: Characterization of oleanolic acid derivative for colon cancer targeting with positron emission tomography. PMID: 24219340 Ref: Tumorigenesis and tumor progression related gene expression profiles in colorectal cancer. PMID: 24240588 Ref: Influence of anthropometric factors on tumour biological characteristics of colorectal cancer in men and women: a cohort study. PMID: 24256736 |
Ref: The cyclin D1 (CCND1) rs9344 G>A polymorphism predicts clinical outcome in colon cancer patients treated with adjuvant 5-FU-based chemotherapy. PMID: 23567490 Ref: PIK3CA and APC mutations are synergistic in the development of intestinal cancers. PMID: 23708654 Ref: Female-specific rectal carcinogenesis in cyclin D1b transgenic mice. PMID: 23975835 Ref: The inflammatory mediator leukotriene D(4) induces subcellular beta-catenin translocation and migration of colon cancer cells. PMID: 24211746 Ref: Adaptation to mTOR kinase inhibitors by amplification of eIF4E to maintain cap-dependent translation. PMID: 24363449 Ref: High expression of IGFBP7 in fibroblasts induced by colorectal cancer cells is co-regulated by TGF-beta and Wnt signaling in a Smad2/3-Dvl2/3-dependent manner. PMID: 24427302 Ref: The impact of cell proliferation markers and p53 mutation status on prognosis of non-metastatic colon cancer. PMID: 24464927 Ref: Comprehensive analysis of beta-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/beta-catenin signaling. PMID: 24467841 Ref: Screening of hub genes and pathways in colorectal cancer with microarray technology. PMID: 24504536 Ref: Dissecting the signaling pathways associated with the oncogenic activity of MLK3 P252H mutation. PMID: 24628919 Ref: microRNA-504 inhibits cancer cell proliferation via targeting CDK6 in hypopharyngeal squamous cell carcinoma. PMID: 24647829 Ref: Prognostic significance of cyclin D1 expression in colorectal cancer: a meta-analysis of observational studies. PMID: 24728073 Ref: Elf3 drives beta-catenin transactivation and associates with poor prognosis in colorectal cancer. PMID: 24874735 Ref: Associations of hormone replacement therapy and oral contraceptives with risk of colorectal cancer defined by clinicopathological factors, beta-catenin alterations, expression of cyclin D1, p53, and microsatellite-instability. PMID: 24885829 Ref: Differential regulation of cyclin D1 expression by protein kinase C alpha and signaling in intestinal epithelial cells. PMID: 24914206 Ref: ATG4B promotes colorectal cancer growth independent of autophagic flux. PMID: 24991826 Ref: Contribution of cyclin D1 (CCND1) and E-cadherin (CDH1) alterations to colorectal cancer susceptibility: a case-control study. PMID: 25146682 Ref: Pan-Bcl-2 inhibitor obatoclax delays cell cycle progression and blocks migration of colorectal cancer cells. PMID: 25192188 Ref: MiR-107 and miR-99a-3p predict chemotherapy response in patients with advanced colorectal cancer. PMID: 25197016 Ref: Concomitant depletion of PTEN and p27 and overexpression of cyclin D1 may predict a worse prognosis for patients with post-operative stage II and III colorectal cancer. PMID: 25202365 Ref: miR-18a inhibits CDC42 and plays a tumour suppressor role in colorectal cancer cells. PMID: 25379703 Ref: Predictive gene signatures: molecular markers distinguishing colon adenomatous polyp and carcinoma. PMID: 25423035 Ref: Influence of inositol hexaphosphate on the expression of selected proliferation markers in IL-1beta-stimulated intestinal epithelial cells. PMID: 25745771 |
Ref: Silymarin induces cyclin D1 proteasomal degradation via its phosphorylation of threonine-286 in human colorectal cancer cells. PMID: 25479723 Ref: LYTAK1, a novel TAK1 inhibitor, suppresses KRAS mutant colorectal cancer cell growth in vitro and in vivo. PMID: 25524577 Ref: Tanshinone I induces cyclin D1 proteasomal degradation in an ERK1/2 dependent way in human colorectal cancer cells. PMID: 25615593 Ref: Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies. PMID: 25671297 Ref: Germ line polymorphisms as predictive markers for pre-surgical radiochemotherapy in locally advanced rectal cancer: a 5-year literature update and critical review. PMID: 25740678 Ref: The significant association of CCND1 genotypes with colorectal cancer in Taiwan. PMID: 25809706 Ref: Colorectal cancer drug target prediction using ontology-based inference and network analysis. PMID: 25818893 Ref: Human colon carcinogenesis is associated with increased interleukin-17-driven inflammatory responses. PMID: 25834404 Ref: [Mechanism of thioridazine-induced apoptosis of human colorectal cancer SW480 cells]. PMID: 25907934 Ref: JARID2 inhibits leukemia cell proliferation by regulating CCND1 expression. PMID: 25939703 Ref: Synergistic inhibition of colon carcinoma cell growth by Hedgehog-Gli1 inhibitor arsenic trioxide and phosphoinositide 3-kinase inhibitor LY294002. PMID: 25945059 Ref: Synergistic effects of AKAP95, Cyclin D1, Cyclin E1, and Cx43 in the development of rectal cancer. PMID: 25973052 Ref: Resibufogenin Induces G1-Phase Arrest through the Proteasomal Degradation of Cyclin D1 in Human Malignant Tumor Cells. PMID: 26121043 Ref: Anti-Proliferative Effect of Naringenin through p38-Dependent Downregulation of Cyclin D1 in Human Colorectal Cancer Cells. PMID: 26157550 Ref: Triphala Extract Suppresses Proliferation and Induces Apoptosis in Human Colon Cancer Stem Cells via Suppressing c-Myc/Cyclin D1 and Elevation of Bax/Bcl-2 Ratio. PMID: 26167492 Ref: In-depth analysis of the critical genes and pathways in colorectal cancer. PMID: 26239303 Ref: TKTL1 promotes cell proliferation and metastasis in esophageal squamous cell carcinoma. PMID: 26349965 Ref: Polymorphisms of cell cycle regulator genes CCND1 G870A and TP53 C215G: Association with colorectal cancer susceptibility risk in a Malaysian population. PMID: 26722315 Ref: MicroRNA-185 is a novel tumor suppressor by negatively modulating the Wnt/beta-catenin pathway in human colorectal cancer. PMID: 27453420 Ref: Immunoexpression of cyclin D1 in colorectal carcinomas is not correlated with survival outcome. PMID: 30023183 |
Ref: Treatment with cucurbitacin B alone and in combination with gefitinib induces cell cycle inhibition and apoptosis via EGFR and JAK/STAT pathway in human colorectal cancer cell lines. PMID: 26183715 Ref: Anti-tumor role of Bacillus subtilis fmbJ-derived fengycin on human colon cancer HT29 cell line. PMID: 26774143 Ref: The involvement of cyclin D1 degradation through GSK3beta-mediated threonine-286 phosphorylation-dependent nuclear export in anti-cancer activity of mulberry root bark extracts. PMID: 26926171 Ref: CRNDE Promotes Malignant Progression of Glioma by Attenuating miR-384/PIWIL4/STAT3 Axis. PMID: 27058823 Ref: Comparative analysis of copy number variations in ulcerative colitis associated and sporadic colorectal neoplasia. PMID: 27080994 Ref: Characterization of cytoplasmic cyclin D1 as a marker of invasiveness in cancer. PMID: 27105504 Ref: microRNA-374a suppresses colon cancer progression by directly reducing CCND1 to inactivate the PI3K/AKT pathway. PMID: 27191497 Ref: CCND1 G870A polymorphism and colorectal cancer risk: An updated meta-analysis. PMID: 27284448 Ref: The coffee diterpene kahweol suppresses the cell proliferation by inducing cyclin D1 proteasomal degradation via ERK1/2, JNK and GKS3beta-dependent threonine-286 phosphorylation in human colorectal cancer cells. PMID: 27424123 Ref: Protocatechualdehyde Induces S-Phase Arrest and Apoptosis by Stimulating the p27(KIP1)-Cyclin A/D1-CDK2 and Mitochondrial Apoptotic Pathways in HT-29 Cells. PMID: 27447597 Ref: Anti-cancer activity of Psoralea fructus through the downregulation of cyclin D1 and CDK4 in human colorectal cancer cells. PMID: 27670681 Ref: Mechanism analysis of colorectal cancer according to the microRNA expression profile. PMID: 27698796 Ref: LDB1 overexpression is a negative prognostic factor in colorectal cancer. PMID: 27713177 Ref: Highly expressed lncRNA CRNDE promotes cell proliferation through Wnt/beta-catenin signaling in renal cell carcinoma. PMID: 27714674 Ref: TCF7L2 and CCND1 polymorphisms and its association with colorectal cancer in Mexican patients. PMID: 27755946 Ref: microRNA-146a inhibits proliferation, migration and invasion of human cervical and colorectal cancer cells. PMID: 27769860 Ref: H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-beta-Catenin Signaling in Colorectal Cancer. PMID: 27789274 Ref: Investigation of cyclin D1 rs9344 G>A polymorphism in colorectal cancer: a meta-analysis involving 13,642 subjects. PMID: 27822068 Ref: [Correlation analysis of G870A CCND1 gene polymorphism with digestive system tumors]. PMID: 27881356 Ref: Anticancer effect of icaritin inhibits cell growth of colon cancer through reactive oxygen species, Bcl-2 and cyclin D1/E signaling. PMID: 27900033 Ref: Combination effects of sorafenib with PI3K inhibitors under hypoxia in colorectal cancer. PMID: 27995152 Ref: Obatoclax, a Pan-BCL-2 Inhibitor, Targets Cyclin D1 for Degradation to Induce Antiproliferation in Human Colorectal Carcinoma Cells. PMID: 28035994 Ref: Akt-dependent activation of Erk by cyclin D1b contributes to cell invasiveness and tumorigenicity. PMID: 28105192 Ref: Identification of potential therapeutic targets for colorectal cancer by bioinformatics analysis. PMID: 28105216 |
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