Primary Site >> Colorectal Cancer
Gene >> CCNB1
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Ref: Unscheduled expression of cyclin B1 and cyclin E in several leukemic and solid tumor cell lines. PMID: 8044772 |
Ref: UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53. PMID: 8667426 Ref: Brefeldin A is a potent inducer of apoptosis in human cancer cells independently of p53. PMID: 8831555 |
Ref: Overexpression of cyclin B1 in human colorectal cancers. PMID: 9030252 Ref: 7-Hydroxystaurosporine (UCN-01) induces apoptosis in human colon carcinoma and leukemia cells independently of p53. PMID: 9260909 Ref: Disorders in cell circuitry associated with multistage carcinogenesis: exploitable targets for cancer prevention and therapy. PMID: 10068276 |
Ref: Sulindac sulfide alters the expression of cyclin proteins in HT-29 colon adenocarcinoma cells. PMID: 9533768 |
Ref: 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage. PMID: 10524633 Ref: Assessment of biomarkers in paired primary and recurrent colorectal adenocarcinomas. PMID: 10613309 Ref: beta-lapachone induces cell cycle arrest and apoptosis in human colon cancer cells. PMID: 10656873 |
Ref: HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation. PMID: 10811625 Ref: Diallyl disulfide inhibits p34(cdc2) kinase activity through changes in complex formation and phosphorylation. PMID: 10837000 Ref: Cell-cycle arrest at G2/M and growth inhibition by apigenin in human colon carcinoma cell lines. PMID: 10900467 |
Ref: Griseofulvin potentiates antitumorigenesis effects of nocodazole through induction of apoptosis and G2/M cell cycle arrest in human colorectal cancer cells. PMID: 11169965 Ref: Dual antitumor effects of 5-fluorouracil on the cell cycle in colorectal carcinoma cells: a novel target mechanism concept for pharmacokinetic modulating chemotherapy. PMID: 11221829 Ref: Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses. PMID: 11431359 Ref: COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib. PMID: 11606477 |
Ref: Mitotic arrest induced by XK469, a novel antitumor agent, is correlated with the inhibition of cyclin B1 ubiquitination. PMID: 11774253 Ref: The relationship between cyclin B1 overexpression and lymph node metastasis in human colorectal cancer. PMID: 11821797 Ref: Piceatannol, a natural analog of resveratrol, inhibits progression through the S phase of the cell cycle in colorectal cancer cell lines. PMID: 11823594 Ref: Overexpression of B-type cyclins alters chromosomal segregation. PMID: 11960377 Ref: The effects of short-chain fatty acids on human colon cancer cell phenotype are associated with histone hyperacetylation. PMID: 11983830 Ref: Immune recognition of cyclin B1 as a tumor antigen is a result of its overexpression in human tumors that is caused by non-functional p53. PMID: 12009577 Ref: Overexpression of Icat induces G(2) arrest and cell death in tumor cell mutants for adenomatous polyposis coli, beta-catenin, or Axin. PMID: 12036951 Ref: Sulfonamide anilides, a novel class of histone deacetylase inhibitors, are antiproliferative against human tumors. PMID: 12154036 Ref: Codon 12 and codon 13 mutations at the K-ras gene induce different soft tissue sarcoma types in nude mice. PMID: 12207005 Ref: Beta-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells. PMID: 12466962 |
Ref: Alterations of anaphase-promoting complex genes in human colon cancer cells. PMID: 12629511 Ref: A novel immunohistochemical method to estimate cell-cycle phase distribution in archival tissue: implications for the prediction of outcome in colorectal cancer. PMID: 14517835 Ref: Recursive partitioning as an approach to selection of immune markers for tumor diagnosis. PMID: 14613989 Ref: Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells. PMID: 14614451 |
Ref: Requirement of Kruppel-like factor 4 in preventing entry into mitosis following DNA damage. PMID: 14627709 Ref: N-methyl-N'-nitro-N-nitrosoguanidine-induced senescence-like growth arrest in colon cancer cells is associated with loss of adenomatous polyposis coli protein, microtubule organization, and telomeric DNA. PMID: 14728717 Ref: Cyclooxygenase-2 (COX-2)-dependent and -independent anticarcinogenic effects of celecoxib in human colon carcinoma cells. PMID: 15041464 Ref: The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe. PMID: 15048074 Ref: Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C. PMID: 15073169 Ref: Correlation of Skp2 with carcinogenesis, invasion, metastasis, and prognosis in colorectal tumors. PMID: 15201993 Ref: Mechanism of sulforaphane-induced cell cycle arrest and apoptosis in human colon cancer cells. PMID: 15231455 Ref: Sulforaphane inhibits human MCF-7 mammary cancer cell mitotic progression and tubulin polymerization. PMID: 15333709 Ref: Prognostic value of cyclin B1 protein expression in colorectal cancer. PMID: 15487447 Ref: Protein-bound polysaccharide from Phellinus linteus induces G2/M phase arrest and apoptosis in SW480 human colon cancer cells. PMID: 15533593 |
Ref: 5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms. PMID: 15547111 Ref: T cell-dependent antibody responses against aberrantly expressed cyclin B1 protein in patients with cancer and premalignant disease. PMID: 15746055 Ref: Expression and gene amplification of primary (A, B1, D1, D3, and E) and secondary (C and H) cyclins in colon adenocarcinomas and correlation with patient outcome. PMID: 15858123 Ref: Inhibition of the growth of premalignant and malignant human oral cell lines by extracts and components of black raspberries. PMID: 15860443 Ref: The histone deacetylase inhibitor butyrate downregulates cyclin B1 gene expression via a p21/WAF-1-dependent mechanism in human colon cancer cells. PMID: 16160080 Ref: JNK1-dependent antimitotic activity of thiazolidin compounds in human non-small-cell lung and colon cancer cells. PMID: 16179969 Ref: Correlation between the expressions of gastrin, somatostatin and cyclin and cyclin-depend kinase in colorectal cancer. PMID: 16437675 |
Ref: Antitumor activity and downregulation of pro-angiogenic molecules in human prostate cancer cells by a novel thiazolidione compound. PMID: 16302260 Ref: Induction of apoptosis and cell cycle arrest by a specific c-Jun NH2-terminal kinase (JNK) inhibitor, SP-600125, in gastrointestinal cancers. PMID: 16337741 Ref: Anticancer activity of the lanthanum compound [tris(1,10-phenanthroline)lanthanum(III)]trithiocyanate (KP772; FFC24). PMID: 16343446 Ref: Discovery and evaluation of dual CDK1 and CDK2 inhibitors. PMID: 16618755 Ref: Methoxyamine potentiates iododeoxyuridine-induced radiosensitization by altering cell cycle kinetics and enhancing senescence. PMID: 16648559 Ref: Checkpoint kinase 1-mediated phosphorylation of Cdc25C and bad proteins are involved in antitumor effects of loratadine-induced G2/M phase cell-cycle arrest and apoptosis. PMID: 16649252 Ref: Investigation of anti-tumor mechanisms of K2154: characterization of tubulin isotypes, mitotic arrest and apoptotic machinery. PMID: 17102938 |
Ref: Induction of cell cycle arrest and apoptosis in HT-29 human colon cancer cells by the dietary compound luteolin. PMID: 16901994 Ref: Targeting serum antibody for cancer diagnosis: a focus on colorectal cancer. PMID: 17227237 Ref: Lidamycin induces marked G2 cell cycle arrest in human colon carcinoma HT-29 cells through activation of p38 MAPK pathway. PMID: 17273739 Ref: [Mechanism study of antisense cyclin B1 in tumorigenesis inhibition using proteomic technique]. PMID: 17355788 Ref: Autoantibodies to Ca2+ binding protein Calnuc is a potential marker in colon cancer detection. PMID: 17390015 Ref: The forkhead box M1 transcription factor contributes to the development and growth of mouse colorectal cancer. PMID: 17408638 Ref: Flavonoid, silibinin, inhibits proliferation and promotes cell-cycle arrest of human colon cancer. PMID: 17950073 Ref: Tetrandrine: a potent abrogator of G2 checkpoint function in tumor cells and its mechanism. PMID: 18348409 |
Ref: Diallyl disulfide induces reversible G2/M phase arrest on a p53-independent mechanism in human colon cancer HCT-116 cells. PMID: 18097607 Ref: Gamma-secretase inhibitors enhance taxane-induced mitotic arrest and apoptosis in colon cancer cells. PMID: 18166351 Ref: Translation inhibition during cell cycle arrest and apoptosis: Mcl-1 is a novel target for RNA binding protein CUGBP2. PMID: 18292181 Ref: CUGBP2 downregulation by prostaglandin E2 protects colon cancer cells from radiation-induced mitotic catastrophe. PMID: 18325984 Ref: Anti-colon cancer effects of Salograviolide A isolated from Centaurea ainetensis. PMID: 18357373 Ref: Translation regulatory factor RBM3 is a proto-oncogene that prevents mitotic catastrophe. PMID: 18427544 Ref: Crude extracts of Solanum lyratum induced cytotoxicity and apoptosis in a human colon adenocarcinoma cell line (colo 205). PMID: 18507053 Ref: Cyclin B1 is an efficacy-predicting biomarker for Chk1 inhibitors. PMID: 18671143 Ref: c-myc antisense oligonucleotides sensitize human colorectal cancer cells to chemotherapeutic drugs. PMID: 18802399 Ref: Long-term stable expression of antisense cDNA of cyclin B1 profoundly inhibits the proliferation of tumor cells and suppresses tumorigenicity in implanted mice. PMID: 18959122 |
Ref: Molecular mechanism of diallyl disulfide in cell cycle arrest and apoptosis in HCT-116 colon cancer cells. PMID: 19202565 Ref: 1-Methylxanthine enhances the radiosensitivity of tumor cells. PMID: 19280470 Ref: Gene expression, cell cycle arrest and MAPK signalling regulation in Caco-2 cells exposed to ellagic acid and its metabolites, urolithins. PMID: 19437480 Ref: Rimonabant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon. PMID: 19479993 Ref: Induction of G1 and G2/M cell cycle arrests by the dietary compound 3,3'-diindolylmethane in HT-29 human colon cancer cells. PMID: 19480695 Ref: Effect of diallyl disulfide on cell cycle arrest of human colon cancer SW480 cells. PMID: 19550124 Ref: Antiproliferative and cytotoxic effects of sodium selenite in human colon cancer cells. PMID: 19602434 Ref: Oxaliplatin-induced gamma-H2AX activation via both p53-dependent and -independent pathways but is not associated with cell cycle arrest in human colorectal cancer cells. PMID: 19735649 Ref: Cytotoxicity mechanisms of pyrazino[1,2-b]isoquinoline-4-ones and SAR studies. PMID: 19875300 Ref: Xanthorrhizol, a natural sesquiterpenoid, induces apoptosis and growth arrest in HCT116 human colon cancer cells. PMID: 19926935 Ref: Anti-proliferative effect of polysaccharides from Salicornia herbacea on induction of G2/M arrest and apoptosis in human colon cancer cells. PMID: 19996705 Ref: Differences in protein expression and gene amplification of cyclins between colon and rectal adenocarcinomas. PMID: 20029639 |
Ref: BCL2L12A localizes to the cell nucleus and induces growth inhibition through G2/M arrest in CHO cells. PMID: 19763795 Ref: c-Jun N-terminal kinase 1 is required for cordycepin-mediated induction of G2/M cell-cycle arrest via p21WAF1 expression in human colon cancer cells. PMID: 19833164 Ref: The synergistic anticancer effect of troglitazone combined with aspirin causes cell cycle arrest and apoptosis in human lung cancer cells. PMID: 19908241 Ref: Cucurbitacin B induces G2 arrest and apoptosis via a reactive oxygen species-dependent mechanism in human colon adenocarcinoma SW480 cells. PMID: 19937855 Ref: Effects of Oplopanax horridus on human colorectal cancer cells. PMID: 20332432 Ref: Suppression of NF-kappaB and GSK-3beta is involved in colon cancer cell growth inhibition by the PPAR agonist troglitazone. PMID: 20540935 Ref: Effects of the biological clock gene Bmal1 on tumour growth and anti-cancer drug activity. PMID: 20576619 Ref: Cyclin B1/Cdk1 phosphorylation of mitochondrial p53 induces anti-apoptotic response. PMID: 20808790 Ref: ML264: An Antitumor Agent that Potently and Selectively Inhibits Kruppel-like Factor Five (KLF5) Expression: A Probe for Studying Colon Cancer Development and Progression PMID: 23762940 |
Ref: Thioredoxin reductase inhibitor ethaselen increases the drug sensitivity of the colon cancer cell line LoVo towards cisplatin via regulation of G1 phase and reversal of G2/M phase arrest. PMID: 20195699 Ref: Satraplatin (JM-216) mediates G2/M cell cycle arrest and potentiates apoptosis via multiple death pathways in colorectal cancer cells thus overcoming platinum chemo-resistance. PMID: 20734047 Ref: 6,7,4'-trihydroxyisoflavone inhibits HCT-116 human colon cancer cell proliferation by targeting CDK1 and CDK2. PMID: 21258042 Ref: Aqueous extract of Curcuma aromatica induces apoptosis and G2/M arrest in human colon carcinoma LS-174-T cells independent of p53. PMID: 21348775 Ref: Cytotoxic and antineoplastic activity of timosaponin A-III for human colon cancer cells. PMID: 21370894 Ref: The antiproliferative effect of dietary fiber phenolic compounds ferulic acid and p-coumaric acid on the cell cycle of Caco-2 cells. PMID: 21500097 Ref: Bortezomib stabilizes mitotic cyclins and prevents cell cycle progression via inhibition of UBE2C in colorectal carcinoma. PMID: 21514426 Ref: A predicted protein, KIAA0247, is a cell cycle modulator in colorectal cancer cells under 5-FU treatment. PMID: 21619678 Ref: Hypoxia signature of splice forms of tryptophanyl-tRNA synthetase marks pancreatic cancer cells with distinct metastatic abilities. PMID: 21926542 |
Ref: Astragalus saponins modulate cell invasiveness and angiogenesis in human gastric adenocarcinoma cells. PMID: 21864667 Ref: Induction of apoptosis and cell cycle arrest by pericarp polyphenol-rich extract of Baneh in human colon carcinoma HT29 cells. PMID: 22119783 Ref: Aloe emodin induces G2/M cell cycle arrest and apoptosis via activation of caspase-6 in human colon cancer cells. PMID: 22343391 Ref: Cordyceps militaris Grown on Germinated Soybean Induces G2/M Cell Cycle Arrest through Downregulation of Cyclin B1 and Cdc25c in Human Colon Cancer HT-29 Cells. PMID: 22474493 Ref: Microarray Analyses of Genes Differentially Expressed by Diet (Black Beans and Soy Flour) during Azoxymethane-Induced Colon Carcinogenesis in Rats. PMID: 22496968 Ref: Nitric oxide-donating aspirin induces G2/M phase cell cycle arrest in human cancer cells by regulating phase transition proteins. PMID: 22552812 Ref: HIV-1 viral protein R (Vpr) induction of apoptosis and cell cycle arrest in multidrug-resistant colorectal cancer cells. PMID: 22552851 Ref: Vector-based miR-15a/16-1 plasmid inhibits colon cancer growth in vivo. PMID: 22574716 Ref: MicroRNA-93 inhibits tumor growth and early relapse of human colorectal cancer by affecting genes involved in the cell cycle. PMID: 22581829 Ref: 6-Gingerol Inhibits Growth of Colon Cancer Cell LoVo via Induction of G2/M Arrest. PMID: 22719783 Ref: Cyclin-dependent kinase-1 (Cdk1)/cyclin B1 dictates cell fate after mitotic arrest via phosphoregulation of antiapoptotic Bcl-2 proteins. PMID: 22965228 Ref: Novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, MHY-449, induces apoptosis and cell cycle arrest in HCT116 human colon cancer cells. PMID: 23064444 |
Ref: The inhibitory effects and mechanisms of rhamnogalacturonan I pectin from potato on HT-29 colon cancer cell proliferation and cell cycle progression. PMID: 22694196 Ref: Mechanism of enhancement of radiation-induced cytotoxicity by sorafenib in colorectal cancer. PMID: 22923745 Ref: Hydroxytyrosyl ethyl ether exhibits stronger intestinal anticarcinogenic potency and effects on transcript profiles compared to hydroxytyrosol. PMID: 23411228 Ref: Anticancer activity of olive oil hydroxytyrosyl acetate in human adenocarcinoma Caco-2 cells. PMID: 23452288 Ref: Genistein-induced G2/M cell cycle arrest of human intestinal colon cancer Caco-2 cells is associated with Cyclin B1 and Chk2 down-regulation. PMID: 23794041 Ref: Anticancer effect of Tamarix gallica extracts on human colon cancer cells involves Erk1/2 and p38 action on G2/M cell cycle arrest. PMID: 23801270 Ref: Higher anti-tumour efficacy of platinum(IV) complex LA-12 is associated with its ability to bypass M-phase entry block induced in oxaliplatin-treated human colon cancer cells. PMID: 24118195 Ref: In Vitro Antiproliferative Effect of Arthrocnemum indicum Extracts on Caco-2 Cancer Cells through Cell Cycle Control and Related Phenol LC-TOF-MS Identification. PMID: 24348703 Ref: Kaempferol Induces Cell Cycle Arrest in HT-29 Human Colon Cancer Cells. PMID: 25337553 |
Ref: Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo. PMID: 23604974 Ref: The role of ERK2 in colorectal carcinogenesis is partly regulated by TRAPPC4. PMID: 23625650 Ref: A novel hydroxamic acid derivative, MHY218, induces apoptosis and cell cycle arrest through downregulation of NF-kappaB in HCT116 human colon cancer cells. PMID: 24190633 Ref: Isorhamnetin suppresses colon cancer cell growth through the PI3KAktmTOR pathway. PMID: 24398569 Ref: Apigenin-induced apoptosis is enhanced by inhibition of autophagy formation in HCT116 human colon cancer cells. PMID: 24626522 Ref: Peptides in common bean fractions inhibit human colorectal cancer cells. PMID: 24679790 Ref: Therapeutic ROS targeting of GADD45gamma in the induction of G2/M arrest in primary human colorectal cancer cell lines by cucurbitacin E. PMID: 24763055 Ref: Cucurbitacin-I, a natural cell-permeable triterpenoid isolated from Cucurbitaceae, exerts potent anticancer effect in colon cancer. PMID: 24858077 Ref: Up-regulation of CNDP2 facilitates the proliferation of colon cancer. PMID: 24885395 Ref: Chk1-induced CCNB1 overexpression promotes cell proliferation and tumor growth in human colorectal cancer. PMID: 24971465 Ref: Design and synthesis of aminostilbene-arylpropenones as tubulin polymerization inhibitors. PMID: 25146959 Ref: Mutated in colorectal cancer (MCC) is a novel oncogene in B lymphocytes. PMID: 25200342 Ref: SKLB316, a novel small-molecule inhibitor of cell-cycle progression, induces G2/M phase arrest and apoptosis in vitro and inhibits tumor growth in vivo. PMID: 25301449 |
Ref: Amplified in breast cancer 1 promotes colorectal cancer progression through enhancing notch signaling. PMID: 25263446 Ref: Aged garlic extract inhibits 1,2-dimethylhydrazine-induced colon tumor development by suppressing cell proliferation. PMID: 25573280 Ref: Phosphorylation-dependent degradation of MEF2C contributes to regulate G2/M transition. PMID: 25789873 Ref: HPIP is upregulated in colorectal cancer and regulates colorectal cancer cell proliferation, apoptosis and invasion. PMID: 25800793 Ref: Effects of KRC-108 on the Aurora A activity and growth of colorectal cancer cells. PMID: 25912878 Ref: A novel class I histone deacetylase inhibitor, I-7ab, induces apoptosis and arrests cell cycle progression in human colorectal cancer cells. PMID: 25960218 Ref: Cyclin b1 suppresses colorectal cancer invasion and metastasis by regulating e-cadherin. PMID: 25962181 Ref: Context-specific role of SOX9 in NF-Y mediated gene regulation in colorectal cancer cells. PMID: 26040697 Ref: CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance. PMID: 26141949 Ref: Carvacrol inhibits proliferation and induces apoptosis in human colon cancer cells. PMID: 26214321 Ref: Enrichment of nuclear S100A4 during G2/M in colorectal cancer cells: possible association with cyclin B1 and centrosomes. PMID: 26349943 Ref: TKTL1 promotes cell proliferation and metastasis in esophageal squamous cell carcinoma. PMID: 26349965 Ref: Identification of a Selective G1-Phase Benzimidazolone Inhibitor by a Senescence-Targeted Virtual Screen Using Artificial Neural Networks. PMID: 26476078 Ref: Antitumor Activity of Americanin A Isolated from the Seeds of Phytolacca americana by Regulating the ATM/ATR Signaling Pathway and the Skp2-p27 Axis in Human Colon Cancer Cells. PMID: 26595875 Ref: p53 Configures the G2/M Arrest Response of Nucleostemin-Deficient Cells. PMID: 26835157 Ref: Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1. PMID: 27030811 |
Ref: Cathepsin B promotes colorectal tumorigenesis, cell invasion, and metastasis. PMID: 25808857 Ref: Long non-coding RNA ZFAS1 interacts with CDK1 and is involved in p53-dependent cell cycle control and apoptosis in colorectal cancer. PMID: 26506418 Ref: BAG3 regulates cell proliferation, migration, and invasion in human colorectal cancer. PMID: 26577854 Ref: Flubendazole induces mitotic catastrophe and senescence in colon cancer cells in vitro. PMID: 26730435 Ref: Antiproliferative effects of triterpenoidal derivatives, obtained from the marine sponge Siphonochalina sp., on human hepatic and colorectal cancer cells. PMID: 26845717 Ref: Insights into the potential of picoplanktonic marine cyanobacteria strains for cancer therapies - Cytotoxic mechanisms against the RKO colon cancer cell line. PMID: 27242042 Ref: Aspirin, platelets, and cancer: The point of view of the internist. PMID: 27344083 Ref: Enhanced expression of long non-coding RNA Sox2ot promoted cell proliferation and motility in colorectal cancer. PMID: 27353770 Ref: Arsenic trioxide induces cell cycle arrest and alters DNA methylation patterns of cell cycle regulatory genes in colorectal cancer cells. PMID: 27769816 Ref: Identification of potential therapeutic targets for colorectal cancer by bioinformatics analysis. PMID: 28105216 |
Ref: BTG1 might be employed as a biomarker for carcinogenesis and a target for gene therapy in colorectal cancers. PMID: 27447746 Ref: MIIP haploinsufficiency induces chromosomal instability and promotes tumour progression in colorectal cancer. PMID: 27741356 Ref: Prognostic role of cyclin B1 in solid tumors: a meta-analysis. PMID: 27903976 Ref: Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway. PMID: 28107519 Ref: 3'-hydroxy-4'-methoxy-beta-methyl-beta-nitrostyrene inhibits tumorigenesis in colorectal cancer cells through ROS-mediated DNA damage and mitochondrial dysfunction. PMID: 28178649 Ref: Lawsone suppresses azoxymethane mediated colon cancer in rats and reduces proliferation of DLD-1 cells via NF-kappaB pathway. PMID: 28222396 Ref: The in vitro and vivo effects of nuclear and cytosolic parafibromin expression on the aggressive phenotypes of colorectal cancer cells: a search of potential gene therapy target. PMID: 28223542 Ref: Tetraarsenic hexoxide induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt suppression and p38 MAPK activation in SW620 human colon cancer cells. PMID: 28355296 Ref: Cellular effects of the microtubule-targeting agent peloruside A in hypoxia-conditioned colorectal carcinoma cells. PMID: 28366502 Ref: Celecoxib enhances the radiosensitivity of HCT116 cells in a COX-2 independent manner by up-regulating BCCIP. PMID: 28386336 Ref: Kanglaite sensitizes colorectal cancer cells to Taxol via NF-kappaBeta inhibition and connexin 43 upregulation. PMID: 28455529 Ref: MHY451 induces cell cycle arrest and apoptosis by ROS generation in HCT116 human colorectal cancer cells. PMID: 28731136 Ref: Metformin Synergistically Potentiates the Antitumor Effects of Imatinib in Colorectal Cancer Cells. PMID: 28785735 Ref: Anticancer Activity of Ramalin, a Secondary Metabolite from the Antarctic Lichen Ramalina terebrata, against Colorectal Cancer Cells. PMID: 28817102 Ref: Knockdown of tripartite motif-59 inhibits the malignant processes in human colorectal cancer cells. PMID: 28849218 Ref: Ginkgetin induces G2-phase arrest in HCT116 colon cancer cells through the modulation of bMyb and miRNA34a expression. PMID: 28902363 Ref: In vitro anticancer activity of new gold(III) porphyrin complexes in colon cancer cells. PMID: 28923355 Ref: Identification of 7-(4'-Cyanophenyl)indoline-1-benzenesulfonamide as a mitotic inhibitor to induce apoptotic cell death and inhibit autophagy in human colorectal cancer cells. PMID: 28963527 Ref: Immature colon carcinoma transcript-1 promotes proliferation of gastric cancer cells. PMID: 29036264 Ref: Immature colon carcinoma transcript-1 promotes cell growth of hepatocellular carcinoma via facilitating cell cycle progression and apoptosis resistance. PMID: 29130100 Ref: The prognostic significance of high/positive expression of cyclin B1 in patients with three common digestive cancers: a systematic review and meta-analysis. PMID: 29221213 |
Ref: UBAP2L silencing inhibits cell proliferation and G2/M phase transition in breast cancer. PMID: 29196913 Ref: Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway. PMID: 29519997 Ref: LncRNA BX357664 inhibits cell proliferation and invasion and promotes cell apoptosis in human colorectal cancer cells. PMID: 29844809 Ref: Quinalizarin Induces Apoptosis through Reactive Oxygen Species (ROS)-Mediated Mitogen-Activated Protein Kinase (MAPK) and Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathways in Colorectal Cancer Cells. PMID: 29860266 Ref: Bax/Tubulin/Epithelial-Mesenchymal Pathways Determine the Efficacy of Silybin Analog HM015k in Colorectal Cancer Cell Growth and Metastasis. PMID: 29875662 Ref: Inhibition of eukaryotic translation initiation factor 4E is effective against chemo-resistance in colon and cervical cancer. PMID: 29959920 Ref: Radiosensitization by irinotecan is attributed to G2/M phase arrest, followed by enhanced apoptosis, probably through the ATM/Chk/Cdc25C/Cdc2 pathway in p53-mutant colorectal cancer cells. PMID: 30085332 Ref: alpha-Hederin Arrests Cell Cycle at G2/M Checkpoint and Promotes Mitochondrial Apoptosis by Blocking Nuclear Factor-kappaB Signaling in Colon Cancer Cells. PMID: 30363706 Ref: UBA2 promotes proliferation of colorectal cancer. PMID: 30387828 |