Primary Site >> Colorectal Cancer

Gene >> CCL3

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Ref: Macrophage inflammatory protein (mip)-1-alpha stem-cell inhibitor (sci) does not affect clonal growth of human solid tumor-cell lines in-vitro.
PMID: 21566931
Ref: Expression of inflammatory chemokines combined with local tumor destruction enhances tumor regression and long-term immunity.
PMID: 14500387
Ref: Cytokines and chemokines are expressed at different levels in small and large murine colon-26 tumors following intratumoral injections of CpG ODN.
PMID: 15548360
Ref: Rofecoxib has different effects on chemokine production in colorectal cancer cells and tumor immune splenocytes.
PMID: 17667525
Ref: Diclofenac, a selective COX-2 inhibitor, inhibits DMH-induced colon tumorigenesis through suppression of MCP-1, MIP-1alpha and VEGF.
PMID: 21268133
Ref: Host-related carcinoembryonic antigen cell adhesion molecule 1 promotes metastasis of colorectal cancer.
PMID: 22469976
Ref: Crucial involvement of the CCL3-CCR5 axis-mediated fibroblast accumulation in colitis-associated carcinogenesis in mice.
PMID: 24510316
Ref: Blockade of the chemokine receptor, CCR5, reduces the growth of orthotopically injected colon cancer cells via limiting cancer-associated fibroblast accumulation.
PMID: 27340784
Ref: CCL3 Enhances Antitumor Immune Priming in the Lymph Node via IFNgamma with Dependency on Natural Killer Cells.
PMID: 29109732
Ref: Circulating Inflammatory Markers and Colorectal Cancer Risk: A Prospective Case-cohort Study in Japan.
PMID: 30132835
Ref: Loss of solute carrier family 7 member 2 exacerbates inflammation-associated colon tumorigenesis.
PMID: 30202097