Primary Site >> Stomach Cancer
Gene >> CCKBR
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Ref: Gastrin receptors in human gastric scirrhous carcinoma. PMID: 2846399 |
Ref: The effect of the gastrin receptor antagonist proglumide on survival in gastric carcinoma. PMID: 2207995 |
Ref: Enterochromaffin-like tumour cells in the diffuse but not the intestinal type of gastric carcinomas. PMID: 1710371 |
Ref: Gastrin antagonists in the treatment of gastric cancer. PMID: 8298161 Ref: Differential mode of action of high- and low-affinity CCK/gastrin receptor antagonists in growth inhibition of gastrin--responsive human gastric adenocarcinoma cells in vitro. PMID: 8317902 |
Ref: A truncated isoform of human CCK-B/gastrin receptor generated by alternative usage of a novel exon. PMID: 7887934 |
Ref: The human histidine decarboxylase promoter is regulated by gastrin and phorbol 12-myristate 13-acetate through a downstream cis-acting element. PMID: 8662934 Ref: Pathophysiology of the fundic enterochromaffin-like (ECL) cell and gastric carcinoid tumours. PMID: 8678447 Ref: Evaluation of cholecystokinin, gastrin, CCK-A receptor, and CCK-B/gastrin receptor gene expressions in gastric cancer. PMID: 8844981 Ref: [Gastrin and gastrin receptor]. PMID: 8920678 |
Ref: Endocytosis of gastrin in cancer cells expressing gastrin/CCK-B receptor. PMID: 8995203 Ref: Gastrin regulates the human histidine decarboxylase promoter through an AP-1-dependent mechanism. PMID: 9142914 Ref: Regulation of growth of human gastric cancer by gastrin and glycine-extended progastrin. PMID: 9287969 |
Ref: Characterization of CCK-B/gastrin-like receptors in human gastric carcinoma. PMID: 9458369 Ref: Sp1 and CREB mediate gastrin-dependent regulation of chromogranin A promoter activity in gastric carcinoma cells. PMID: 9852054 Ref: Expression of progastrin-derived peptides and gastrin receptors in a panel of gastrointestinal carcinoma cell lines. PMID: 10221825 Ref: The role of endogenous gastrin in the development of enterochromaffin-like cell carcinoid tumors in Mastomys natalensis: a study with the specific gastrin receptor antagonist AG-041R. PMID: 10461356 |
Ref: A comparison of an anti-gastrin antibody and cytotoxic drugs in the therapy of human gastric ascites in SCID mice. PMID: 10188727 Ref: [The action of proglumide blocking gastrin on gastric cancer cells]. PMID: 11829855 |
Ref: Phase I/II study of G17-DT, an anti-gastrin immunogen, in advanced colorectal cancer. PMID: 11156225 |
Ref: Frameshift mutations of human gastrin receptor gene (hGARE) in gastrointestinal cancers with microsatellite instability. PMID: 11896205 Ref: Mechanism of activation of protein kinase D2(PKD2) by the CCK(B)/gastrin receptor. PMID: 12058027 |
Ref: Influence of gastrin on the expression of cyclooxygenase-2, hepatocyte growth factor and apoptosis-related proteins in gastric epithelial cells. PMID: 12674216 Ref: Transcriptional regulation of the human trefoil factor, TFF1, by gastrin. PMID: 12891554 |
Ref: Coexpression of cholecystokinin-B/gastrin receptor and gastrin gene in human gastric tissues and gastric cancer cell line. PMID: 15040018 Ref: Gastrins, cholecystokinins and gastrointestinal cancer. PMID: 15238241 Ref: [Human gastric tissues coexpress two different splicing cholecystokinin-B/gastrin receptors]. PMID: 15250152 Ref: Human gastric tissues simultaneously express the classical and alternative splicing cholecystokinin-B/gastrin receptors. PMID: 15989082 |
Ref: Long-term effects of proglumide on resection of cardiac adenocarcinoma. PMID: 15849809 Ref: Expression of some tumor associated factors in human carcinogenesis and development of gastric carcinoma. PMID: 15929170 Ref: [Expression of gastrin in human gastric cancer cell line and effect of anti-gastrin mAb on the cell growth]. PMID: 15996318 Ref: Growth effect of gastrin on gastric cancer and its clinical implications for gastric cancer surgery. PMID: 16012719 |
Ref: Expression of gastrin and its receptor in human gastric cancer tissues. PMID: 16228228 Ref: [Effects of gastrin receptor antagonist and cyclooxygenase-2 inhibitor on proliferation and apoptosis of gastric cancer cell]. PMID: 16677505 Ref: [Blocking the gastrin/cholecystokinin-B receptor autocrine loop influences the growth and apoptosis of human gastric cancer cells]. PMID: 17064598 |
Ref: G17DT: an antigastrin immunogen for the treatment of gastrointestinal malignancy. PMID: 17309331 Ref: Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2. PMID: 17962809 |
Ref: [Effect of gastrin on tyrosine phosphorylation of focal adhesion kinase in human gastric cancer cell line SGC7901]. PMID: 18184462 Ref: Blockade of cholecystokinin-2 receptor and cyclooxygenase-2 synergistically induces cell apoptosis, and inhibits the proliferation of human gastric cancer cells in vitro. PMID: 18258354 Ref: Gastrin-mediated interleukin-8 and cyclooxygenase-2 gene expression: differential transcriptional and posttranscriptional mechanisms. PMID: 18395088 Ref: Time-dependent component-specific regulation of gastric acid secretion-related proteins by roasted coffee constituents. PMID: 18448837 |
Ref: Mixed lineage kinase-3/JNK1 axis promotes migration of human gastric cancer cells following gastrin stimulation. PMID: 20150185 Ref: Altered expression of MiR-148a and MiR-152 in gastrointestinal cancers and its clinical significance. PMID: 20422307 Ref: Blocking gastrin and CCK-B autocrine loop affects cell proliferation and apoptosis in vitro. PMID: 20559691 Ref: Glycogen Synthase Kinase-3beta regulates Snail and beta-catenin during gastrin-induced migration of gastric cancer cells. PMID: 20637111 |
Ref: MicroRNA-148b is frequently down-regulated in gastric cancer and acts as a tumor suppressor by inhibiting cell proliferation. PMID: 21205300 |
Ref: Induction of gastrin expression in gastrointestinal cells by hypoxia or cobalt is independent of hypoxia-inducible factor (HIF). PMID: 22593272 |
Ref: EGR1 is critical for gastrin-dependent upregulation of anion exchanger 2 in gastric cancer cells. PMID: 23121767 Ref: rG17PE38, a novel immunotoxin target to gastric cancer with overexpressed CCK-2R. PMID: 23311704 Ref: Selection of potential therapeutic human single-chain Fv antibodies against cholecystokinin-B/gastrin receptor by phage display technology. PMID: 23344946 Ref: Gastrin acting on the cholecystokinin2 receptor induces cyclooxygenase-2 expression through JAK2/STAT3/PI3K/Akt pathway in human gastric cancer cells. PMID: 23376640 Ref: The role of proteasome beta subunits in gastrin-mediated transcription of plasminogen activator inhibitor-2 and regenerating protein1. PMID: 23544109 Ref: Progastrin stimulates colonic cell proliferation via CCK2R- and beta-arrestin-dependent suppression of BMP2. PMID: 23891976 |
Ref: The regulation of gastric acid secretion - clinical perspectives. PMID: 24279703 |
Ref: CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis. PMID: 24951258 Ref: Expression, purification and characterization of recombinant toxins consisting of truncated gastrin 17 and pseudomonas exotoxin. PMID: 25353354 Ref: Trastuzumab Inhibits Growth of HER2-Negative Gastric Cancer Cells Through Gastrin-Initialized CCKBR Signaling. PMID: 26173505 |
Ref: Gastrokine 1 inhibits gastrin-induced cell proliferation. PMID: 25752269 Ref: Heterogeneous expression of cholecystokinin and gastrin receptor in stomach and pancreatic cancer: An immunohistochemical study. PMID: 27072272 Ref: Gastrin-induced miR-222 promotes gastric tumor development by suppressing p27kip1. PMID: 27323780 Ref: Gastrin promotes the metastasis of gastric carcinoma through the beta-catenin/TCF-4 pathway. PMID: 27430592 Ref: MiR-148a Functions as a Tumor Suppressor by Targeting CCK-BR via Inactivating STAT3 and Akt in Human Gastric Cancer. PMID: 27518872 Ref: Gastrin and upper GI cancers. PMID: 27591354 Ref: Zinc Ions Mediate Gastrin Expression, Proliferation, and Migration Downstream of the Cholecystokinin-2 Receptor. PMID: 27797597 |
Ref: Gastrin activates autophagy and increases migration and survival of gastric adenocarcinoma cells. PMID: 28109268 Ref: Complexes of gastrin with In(3+), Ru(3+) or Ga(3+) ions are not recognised by the cholecystokinin 2 receptor. PMID: 28702751 Ref: The cytoprotective protein clusterin is overexpressed in hypergastrinemic rodent models of oxyntic preneoplasia and promotes gastric cancer cell survival. PMID: 28902909 Ref: CXCR4-expressing Mist1(+) progenitors in the gastric antrum contribute to gastric cancer development. PMID: 29340033 |
Ref: Expression of the Cholecystokinin-B Receptor in Neoplastic Gastric Cells. PMID: 28980157 |