Primary Site >> Colorectal Cancer

Gene >> CCK

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Ref: Evidence for autocrine growth stimulation of cultured colon tumor cells by a gastrin/cholecystokinin-like peptide.
PMID: 2298233
Ref: CCK-8 and gastrin plasma levels in cholecystectomized and colorectal cancer patients.
PMID: 8245672
Ref: Antiproliferative gastrin/cholecystokinin receptor antagonists target the 78-kDa gastrin-binding protein.
PMID: 8052625
Ref: Gastrin stimulates growth of human colon cancer cells via a receptor other than CCK-A or CCK-B.
PMID: 8060296
Ref: Regulation of growth of human gastric cancer by gastrin and glycine-extended progastrin.
PMID: 9287969
Ref: Involvement of cholecystokinin/gastrin-related peptides and their receptors in clinical gastrointestinal disorders.
PMID: 12688377
Ref: Gastrins, cholecystokinins and gastrointestinal cancer.
PMID: 15238241
Ref: Analysis of the cellular and molecular mechanisms of trophic action of a misspliced form of the type B cholecystokinin receptor present in colon and pancreatic cancer.
PMID: 15837546
Ref: Gastrin 1-6 promotes growth of colon cancer cells through non-CCK receptors.
PMID: 17126952
Ref: Targeting of a CCK(2) receptor splice variant with (111)In-labelled cholecystokinin-8 (CCK8) and (111)In-labelled minigastrin.
PMID: 17934729
Ref: Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice.
PMID: 19652364
Ref: A novel immunotoxin - rCCK8PE38 targeting of CCK-R overexpressed colon cancers.
PMID: 25673265
Ref: Germline Mutation of the CCK Receptor: A Novel Biomarker for Pancreas Cancer.
PMID: 26741064
Ref: Dual-agonist occupancy of orexin receptor 1 and cholecystokinin A receptor heterodimers decreases G-protein-dependent signaling and migration in the human colon cancer cell line HT-29.
PMID: 28288880