Primary Site >> Colorectal Cancer

Gene >> CBX8

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Ref: XR3054, structurally related to limonene, is a novel inhibitor of farnesyl protein transferase.
PMID: 10533487
Ref: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) for treatment of prostate cancer: first results and review of the literature.
PMID: 12497168
Ref: Peptides and antitumor activity. Development and investigation of some peptides with antitumor activity.
PMID: 10866357
Ref: The mismatch repair gene hMSH2 is mutated in the prostate cancer cell line LNCaP.
PMID: 11025778
Ref: Development of C-20 modified betulinic acid derivatives as antitumor agents.
PMID: 11527742
Ref: Antitumor effects in mice of low-dose (metronomic) cyclophosphamide administered continuously through the drinking water.
PMID: 12019144
Ref: Potentiation of the antiproliferative activity of MKT-077 by loperamide, diltiazem and tamoxifen.
PMID: 14534737
Ref: A cox-2 promoter-based replication-selective adenoviral vector to target the cox-2-expressing human bladder cancer cells.
PMID: 15240520
Ref: Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells.
PMID: 15623604
Ref: Comparative anti-tumor efficacy of two orally administered platinum(IV) drugs in nude mice bearing human tumor xenografts.
PMID: 16428939
Ref: Human osteocalcin: a strong promoter for nitric oxide synthase gene therapy, with specificity for hormone refractory prostate cancer.
PMID: 17471586
Ref: Binding and internalization of NGR-peptide-targeted liposomal doxorubicin (TVT-DOX) in CD13-expressing cells and its antitumor effects.
PMID: 17893520
Ref: Direct and distant antitumor effects of a telomerase-selective oncolytic adenoviral agent, OBP-301, in a mouse prostate cancer model.
PMID: 18274558
Ref: Baicalein overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance via two different cell-specific pathways in cancer cells but not in normal cells.
PMID: 18974136
Ref: Human tumor growth in nude mice is associated with decreased plasma cysteine and homocysteine.
PMID: 19035276
Ref: In vitro anticancer potential of tree extracts from the Walloon Region forest.
PMID: 19579185
Ref: Synthesis and anticancer activities of new 3-allylthio-6-(mono or disubstituted)aminopyridazines.
PMID: 20195817
Ref: The phosphoinositide 3-kinase inhibitor PI-103 downregulates choline kinase alpha leading to phosphocholine and total choline decrease detected by magnetic resonance spectroscopy.
PMID: 20551061
Ref: High susceptibility of metastatic cells derived from human prostate and colon cancer cells to TRAIL and sensitization of TRAIL-insensitive primary cells to TRAIL by 4,5-dimethoxy-2-nitrobenzaldehyde.
PMID: 21513580
Ref: Novel methylene modified cyclohexyl ethylenediamine-N,N'-diacetate ligands and their platinum(IV) complexes. Influence on biological activity.
PMID: 22369771
Ref: STI571 reduces TRAIL-induced apoptosis in colon cancer cells: c-Abl activation by the death receptor leads to stress kinase-dependent cell death.
PMID: 22462553
Ref: Synthesis and characterization of bicalutamide-loaded magnetic nanoparticles as anti-tumor drug carriers.
PMID: 22630012
Ref: Platinum(II/IV) complexes containing ethylenediamine-N,N'-di-2/3-propionate ester ligands induced caspase-dependent apoptosis in cisplatin-resistant colon cancer cells.
PMID: 22820831
Ref: Synthesis and biological evaluation of N-substituted noscapine analogues.
PMID: 23055449
Ref: Matched rabbit monoclonal antibodies against alphav-series integrins reveal a novel alphavbeta3-LIBS epitope, and permit routine staining of archival paraffin samples of human tumors.
PMID: 23213423
Ref: Herbal infusions; their phenolic profile, antioxidant and anti-inflammatory effects in HT29 and PC3 cells.
PMID: 23712099
Ref: Enzymatic properties and anticancer activity of L-lysine alpha-oxidase from Trichoderma cf. aureoviride Rifai BKMF-4268D.
PMID: 23777857
Ref: GE132+Natural: Novel promising dietetic supplement with antiproliferative influence on prostate, colon, and breast cancer cells.
PMID: 23818369
Ref: Synthetic lethal targeting of PTEN-deficient cancer cells using selective disruption of polynucleotide kinase/phosphatase.
PMID: 23883586
Ref: Mutational Analysis of Circulating Tumor Cells Using a Novel Microfluidic Collection Device and qPCR Assay.
PMID: 24151533
Ref: Phenolic profiles and antioxidant and anticarcinogenic activities of Greek herbal infusions; balancing delight and chemoprevention?
PMID: 24001836
Ref: The gastrin/cholecystokinin-B receptor on prostate cells--a novel target for bifunctional prostate cancer imaging.
PMID: 24211650
Ref: MHY-449, a novel dihydrobenzofuro[4,5-b][1,8] naphthyridin-6-one derivative, induces apoptotic cell death through modulation of Akt/FoxO1 and ERK signaling in PC3 human prostate cancer cells.
PMID: 24424889
Ref: N-(5-Mercapto-1,3,4-Thiadiazol-2-yl)-2-Phenylacetamide Derivatives: Synthesis and In-vitro Cytotoxicity Evaluation as Potential Anticancer Agents.
PMID: 25237343
Ref: Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer.
PMID: 25360999
Ref: Dose- and time-dependent gene expression alterations in prostate and colon cancer cells after in vitro exposure to carbon ion and X-irradiation.
PMID: 25190155
Ref: Insulin-Like Growth Factor-1 Modulates Polycomb Cbx8 Expression and Inhibits Colon Cancer Cell Apoptosis.
PMID: 25398592
Ref: Novel series of coumarinyl substituted-thiazolidin-2,4-dione analogs as anticancer agents: design, synthesis, spectral studies and cytotoxicity evaluation.
PMID: 25909852
Ref: In vitro chemo-preventive activities of hydroxytyrosol: the main phenolic compound present in extra-virgin olive oil.
PMID: 26469183
Ref: Utilization of Cyanoacetohydrazide and Oxadiazolyl Acetonitrile in the Synthesis of Some New Cytotoxic Heterocyclic Compounds.
PMID: 26840279
Ref: Synthesis and Characterization of Some New Coumarins with in Vitro Antitumor and Antioxidant Activity and High Protective Effects against DNA Damage.
PMID: 26907244
Ref: A novel dual-functioning ruthenium(II)-arene complex of an anti-microbial ciprofloxacin derivative - Anti-proliferative and anti-microbial activity.
PMID: 26993079
Ref: Higher Initial DNA Damage and Persistent Cell Cycle Arrest after Carbon Ion Irradiation Compared to X-irradiation in Prostate and Colon Cancer Cells.
PMID: 27148479
Ref: Titanocene-Gold Complexes Containing N-Heterocyclic Carbene Ligands Inhibit Growth of Prostate, Renal, and Colon Cancers in Vitro.
PMID: 27182101
Ref: Synthesis and antitumor activity of selenium-containing quinone-based triazoles possessing two redox centres, and their mechanistic insights.
PMID: 27341379
Ref: Transcriptome analysis of copper homeostasis genes reveals coordinated upregulation of SLC31A1,SCO1, and COX11 in colorectal cancer.
PMID: 27516958
Ref: Two-stage nanoparticle delivery of piperlongumine and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) anti-cancer therapy.
PMID: 27853735
Ref: Synthesis and anticancer activity of new [(Indolyl)pyrazolyl]-1,3,4-oxadiazole thioglycosides and acyclic nucleoside analogs.
PMID: 28613111
Ref: In vitro-fermented raw and roasted walnuts induce expression of CAT and GSTT2 genes, growth inhibition, and apoptosis in LT97 colon adenoma cells.
PMID: 29241580
Ref: Chemopreventive Potential of Raw and Roasted Pistachios Regarding Colon Carcinogenesis.
PMID: 29258268
Ref: Synthesis of Selenium-Quinone Hybrid Compounds with Potential Antitumor Activity via Rh-Catalyzed C-H Bond Activation and Click Reactions.
PMID: 29301214
Ref: Bio-Catalytic Structural Transformation of Anti-cancer Steroid, Drostanolone Enanthate with Cephalosporium aphidicola and Fusarium lini, and Cytotoxic Potential Evaluation of Its Metabolites against Certain Cancer Cell Lines.
PMID: 29326586
Ref: Chemopreventive Potential of In Vitro Fermented Raw and Roasted Hazelnuts in LT97 Colon Adenoma Cells.
PMID: 29277760
Ref: Alterations in the p53-SOCS2 axis contribute to tumor growth in colon cancer.
PMID: 29622769
Ref: Quinonoid compounds via reactions of lawsone and 2-aminonaphthoquinone with alpha-bromonitroalkenes and nitroallylic acetates: Structural diversity by C-ring modification and cytotoxic evaluation against cancer cells.
PMID: 29660689
Ref: lH-Pyrazolo[3,4-b]quinolin-3-amine derivatives inhibit growth of colon cancer cells via apoptosis and sub G1 cell cycle arrest.
PMID: 29853331
Ref: URG11 Regulates Prostate Cancer Cell Proliferation, Migration, and Invasion.
PMID: 29955600
Ref: Acetyl-11-keto-beta-boswellic acid suppresses docetaxel-resistant prostate cancer cells in vitro and in vivo by blocking Akt and Stat3 signaling, thus suppressing chemoresistant stem cell-like properties.
PMID: 30171201
Ref: CBX8 and CD96 Are Important Prognostic Biomarkers of Colorectal Cancer.
PMID: 30383736