Primary Site >> Colorectal Cancer
Gene >> CBS
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Ref: A mass screening program for colorectal cancer using chemical testing for occult blood in the stool. PMID: 7388738 |
Ref: Indirect immunofluorescence studies of proliferating cell nuclear antigen in nucleoli of human tumor and normal tissues. PMID: 6134581 |
Ref: Identification of endogenous inhibitory growth factors from a human colon carcinoma cell line. PMID: 3857117 |
Ref: Determination of the levels of urokinase and its receptor in human colon carcinoma cell lines. PMID: 2835152 Ref: Epithelial polarity, villin expression, and enterocytic differentiation of cultured human colon carcinoma cells: a survey of twenty cell lines. PMID: 3349466 |
Ref: Invasion of extracellular matrix by cultured colon cancer cells: dependence on urokinase receptor display. PMID: 2164413 Ref: Evidence for autocrine growth stimulation of cultured colon tumor cells by a gastrin/cholecystokinin-like peptide. PMID: 2298233 |
Ref: Transduction and expression of the human carcinoembryonic antigen gene in a murine colon carcinoma cell line. PMID: 1712245 |
Ref: Sensitivity of nuclear c-myc levels and induction to differentiation-inducing agents in human colon tumor cell lines. PMID: 1540946 |
Ref: Repression of autocrine transforming growth factor beta 1 and beta 2 in quiescent CBS colon carcinoma cells leads to progression of tumorigenic properties. PMID: 8494782 |
Ref: Neurotensin receptor and its mRNA are expressed in many human colon cancer cell lines but not in normal colonic epithelium: binding studies and RT-PCR experiments. PMID: 7521165 Ref: Autocrine transforming growth factor-beta 1 and beta 2 expression is increased by cell crowding and quiescence in colon carcinoma cells. PMID: 8082724 Ref: Inhibition of CRIPTO expression and tumorigenicity in human colon cancer cells by antisense RNA and oligodeoxynucleotides. PMID: 8302592 |
Ref: Macrophage colony-stimulating factor enhancement of antibody-dependent cellular cytotoxicity against human colon carcinoma cells. PMID: 8537095 Ref: Cooperative antiproliferative effects of 8-chloro-cyclic AMP and 528 anti-epidermal growth factor receptor monoclonal antibody on human cancer cells. PMID: 9815969 |
Ref: Transferrin and insulin enhance human colon tumor cell growth by differentiation class specific mechanisms. PMID: 8938790 Ref: Autocrine transforming growth factor-beta (TGF beta) modulates the 120 kD and 105 kD retinoblastoma (RB) protein species in CBS colon carcinoma cells as revealed by an anti-sense TGF beta 1 expression vector. PMID: 21544384 Ref: Cell mediated cytotoxicity of human colon carcinoma cells by a monoclonal antibody (R4) recognizing the carcinoembryonic antigen (CEA) and CEA-related molecules. PMID: 21544473 |
Ref: Expression of TGFalpha autocrine activity in human colon carcinoma CBS cells is autoregulated and independent of exogenous epidermal growth factor. PMID: 9525476 Ref: Autocrine transforming growth factor alpha provides a growth advantage to malignant cells by facilitating re-entry into the cell cycle from suboptimal growth states. PMID: 9813060 Ref: Expression of mucin-associated sulfo-Lea carbohydrate epitopes on human colon carcinoma cells. PMID: 10081487 |
Ref: Contextual effects of transforming growth factor beta on the tumorigenicity of human colon carcinoma cells. PMID: 10493532 |
Ref: A polymorphism in the methylenetetrahydrofolate reductase gene predisposes to colorectal cancers with microsatellite instability. PMID: 11889073 Ref: B-vitamin intake, metabolic genes, and colorectal cancer risk (United States). PMID: 12020105 |
Ref: Extracellular calcium and calcium sensing receptor function in human colon carcinomas: promotion of E-cadherin expression and suppression of beta-catenin/TCF activation. PMID: 12517779 Ref: Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study. PMID: 12730865 |
Ref: Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review. PMID: 14977639 |
Ref: Calcium sensing receptor in human colon carcinoma: interaction with Ca(2+) and 1,25-dihydroxyvitamin D(3). PMID: 15695391 Ref: Influence of folate status on genomic DNA methylation in colonic mucosa of subjects without colorectal adenoma or cancer. PMID: 15726099 Ref: Upregulation of calcium-sensing receptor and mitogen-activated protein kinase signalling in the regulation of growth and differentiation in colon carcinoma. PMID: 16278666 |
Ref: Regulation of E-cadherin and beta-catenin by Ca2+ in colon carcinoma is dependent on calcium-sensing receptor expression and function. PMID: 17557293 |
Ref: Polymorphisms in methionine synthase (A2756G) and cystathionine beta-synthase (844ins68) and susceptibility to carcinomas of the upper gastrointestinal tract. PMID: 17726616 Ref: Switch of transforming growth factor beta function from tumor suppression to stimulation in adenomatous polyposis coli (APC) knocked-down human colon carcinoma cells. PMID: 18774639 Ref: Heterogeneity of receptor function in colon carcinoma cells determined by cross-talk between type I insulin-like growth factor receptor and epidermal growth factor receptor. PMID: 18829558 |
Ref: Vitamin D mediates its action in human colon carcinoma cells in a calcium-sensing receptor-dependent manner: downregulates malignant cell behavior and the expression of thymidylate synthase and survivin and promotes cellular sensitivity to 5-FU. PMID: 19621386 Ref: Butyrate-stimulated H2S production in colon cancer cells. PMID: 19803745 Ref: Hydrogen sulfide induces human colon cancer cell proliferation: role of Akt, ERK and p21. PMID: 20184555 Ref: Effects of potential calcium sensing receptor inducers on promoting chemosensitivity of human colon carcinoma cells. PMID: 20428782 Ref: The role of transforming growth factor-beta in suppression of hepatic metastasis from colon cancer. PMID: 20815859 |
Ref: Interaction of endocannabinoid system and steroid hormones in the control of colon cancer cell growth. PMID: 21412772 Ref: Transforming growth factor-beta suppresses metastasis in a subset of human colon carcinoma cells. PMID: 22672900 Ref: Frequent epigenetic silencing of the folate-metabolising gene cystathionine-beta-synthase in gastrointestinal cancer. PMID: 23152928 |
Ref: Isolation and characterization of calcium sensing receptor null cells: a highly malignant and drug resistant phenotype of colon cancer. PMID: 23055106 Ref: Folate-genetics and colorectal neoplasia: what we know and need to know next. PMID: 23401104 Ref: Cellular responses to TGFbeta and TGFbeta receptor expression in human colonic epithelial cells require CaSR expression and function. PMID: 23639611 Ref: Tumor-derived hydrogen sulfide, produced by cystathionine-beta-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer. PMID: 23836652 Ref: [Correlation of methylation of CpG island in cystathionine beta synthase promoter and clinicopathological features in colorectal cancer]. PMID: 24054011 |
Ref: In vivo analysis of insulin-like growth factor type 1 receptor humanized monoclonal antibody MK-0646 and small molecule kinase inhibitor OSI-906 in colorectal cancer. PMID: 24173770 Ref: Akt inhibitor MK-2206 promotes anti-tumor activity and cell death by modulation of AIF and Ezrin in colorectal cancer. PMID: 24581231 Ref: Effect of S-adenosyl-L-methionine (SAM), an allosteric activator of cystathionine-beta-synthase (CBS) on colorectal cancer cell proliferation and bioenergetics in vitro. PMID: 24667534 |
Ref: Genetic modifiers of folate, vitamin B-12, and homocysteine status in a cross-sectional study of the Canadian population. PMID: 25948668 Ref: CTCF/cohesin-binding sites are frequently mutated in cancer. PMID: 26053496 Ref: Induction of calcium sensing receptor in human colon cancer cells by calcium, vitamin D and aquamin: Promotion of a more differentiated, less malignant and indolent phenotype. PMID: 26076051 Ref: Hydrogen Sulfide and Cancer. PMID: 26162838 Ref: Methylation diet and methyl group genetics in risk for adenomatous polyp occurrence. PMID: 26673393 |
Ref: 5-FU targets rpL3 to induce mitochondrial apoptosis via cystathionine-beta-synthase in colon cancer cells lacking p53. PMID: 27385096 Ref: Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine beta-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of col PMID: 27521834 Ref: The gastrointestinal tract - a central organ of cannabinoid signaling in health and disease. PMID: 27561826 |
Ref: Mapping of DNA Hypermethylation and Hypomethylation induced by Folate Deficiency in Sporadic Colorectal Cancer and Clinical Implication Analysis of Hypermethylation Pattern in CBS Promoter. PMID: 28397458 Ref: Photoacoustic probes for real-time tracking of endogenous H2S in living mice. PMID: 28507667 Ref: DNA hypomethylation of CBS promoter induced by folate deficiency is a potential noninvasive circulating biomarker for colorectal adenocarcinomas. PMID: 28881655 Ref: Upregulation of Cystathionine-beta-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis. PMID: 28923859 |
Ref: Drug resistance induces the upregulation of H2S-producing enzymes in HCT116 colon cancer cells. PMID: 29061341 Ref: Role of endogenous and exogenous nitric oxide, carbon monoxide and hydrogen sulfide in HCT116 colon cancer cell proliferation. PMID: 29074106 Ref: Increased colon cancer risk after severe Salmonella infection. PMID: 29342165 Ref: A Review of Hydrogen Sulfide Synthesis, Metabolism, and Measurement: Is Modulation of Hydrogen Sulfide a Novel Therapeutic for Cancer? PMID: 29790379 Ref: Antitumor effect of sikokianin C, a selective cystathionine beta-synthase inhibitor, against human colon cancer in vitro and in vivo. PMID: 30108905 |