Primary Site >> Colorectal Cancer
Gene >> CBL
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Ref: The critical role of blood from HLA-homozygous donors in fatal transfusion-associated graft-versus-host disease in immunocompetent patients. PMID: 2003327 |
Ref: C-Cbl protein in human cancer tissues is frequently tyrosine phosphorylated in a tumor-specific manner. PMID: 10891544 |
Ref: Gene selection in cancer classification using sparse logistic regression with Bayesian regularization. PMID: 16844704 |
Ref: Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the anti-EGFR monoclonal antibody cetuximab. PMID: 17804738 |
Ref: p38 MAP kinase controls EGF receptor downregulation via phosphorylation at Ser1046/1047. PMID: 19138820 Ref: (-)-Epigallocatechin gallate downregulates EGF receptor via phosphorylation at Ser1046/1047 by p38 MAPK in colon cancer cells. PMID: 19578043 |
Ref: Sprouty2 protein enhances the response to gefitinib through epidermal growth factor receptor in colon cancer cells. PMID: 20624167 |
Ref: EphrinA5 suppresses colon cancer development by negatively regulating epidermal growth factor receptor stability. PMID: 22074469 |
Ref: Berberine inhibits proliferation and down-regulates epidermal growth factor receptor through activation of Cbl in colon tumor cells. PMID: 23457600 |
Ref: SLAP displays tumour suppressor functions in colorectal cancer via destabilization of the SRC substrate EPHA2. PMID: 24457997 Ref: Up-regulation of c-Cbl suggests its potential role as oncogene in primary colorectal cancer. PMID: 24525700 Ref: The tyrosine phosphatase PTPRO sensitizes colon cancer cells to anti-EGFR therapy through activation of SRC-mediated EGFR signaling. PMID: 25301722 |
Ref: Complex of MUC1, CIN85 and Cbl in Colon Cancer Progression and Metastasis. PMID: 25675408 Ref: Polymorphisms in Genes Involved in EGFR Turnover Are Predictive for Cetuximab Efficacy in Colorectal Cancer. PMID: 26206335 |
Ref: NADPH Oxidase 1 Activity and ROS Generation Are Regulated by Grb2/Cbl-Mediated Proteasomal Degradation of NoxO1 in Colon Cancer Cells. PMID: 26781991 Ref: c-Cbl mediates the degradation of tumorigenic nuclear beta-catenin contributing to the heterogeneity in Wnt activity in colorectal tumors. PMID: 27661103 |
Ref: Cortactin promotes colorectal cancer cell proliferation by activating the EGFR-MAPK pathway. PMID: 27903975 Ref: MicroRNA-155 regulates the proliferation, cell cycle, apoptosis and migration of colon cancer cells and targets CBL. PMID: 29104623 |
Ref: c-Cbl Expression Correlates with Human Colorectal Cancer Survival and Its Wnt/beta-Catenin Suppressor Function Is Regulated by Tyr371 Phosphorylation. PMID: 30029779 |