Primary Site >> Colorectal Cancer
Gene >> CAT
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Ref: A study of some mitochondrial and peroxisomal enzymes in human colonic adenocarcinoma. PMID: 6256583 |
Ref: Kinetics and function of tumor cytotoxic factor(s) produced by human blood monocytes activated to the tumoricidal state. PMID: 3856062 |
Ref: [Usefulness of transrectal echography in the study of rectal cancer]. PMID: 2083118 Ref: Oxidant defense mechanisms in the human colon. PMID: 2090586 |
Ref: Effect of reactive oxygen intermediates on the in vitro invasive capacity of tumor cells and liver metastasis in mice. PMID: 8392985 |
Ref: Human breast and colon cancers exhibit alterations of DNA methylation patterns at several DNA segments on chromosomes 11p and 17p. PMID: 7806594 Ref: Modifications of the anti-oxidant metabolism during proliferation and differentiation of colon tumor cell lines. PMID: 7989127 Ref: Interferon-gamma enhances monoclonal antibody 17-1A-dependent neutrophil cytotoxicity toward colorectal carcinoma cell line SW11-16. PMID: 8137553 |
Ref: Polyphenols as cancer chemopreventive agents. PMID: 8538195 Ref: Increased antioxidant enzyme activities in the colorectal adenoma and carcinoma. PMID: 8552207 |
Ref: Vulnerability of multidrug-resistant tumor cells to the aromatic fatty acids phenylacetate and phenylbutyrate. PMID: 9816242 |
Ref: Genetic alterations and oxidative metabolism in sporadic colorectal tumors from a Spanish community. PMID: 9142218 Ref: Catalase activity in erythrocytes from colon and gastric cancer patients. Influence of nickel, lead, mercury, and cadmium. PMID: 9258471 |
Ref: Antioxidant enzyme defence responses of human MCF-7 and SW480 cancer cells to conjugated linoleic acid. PMID: 10470140 |
Ref: Multiple autocrine factors including an extracellular matrix protein are required for the proliferation and spreading of human colon carcinoma cells in vitro. PMID: 10831071 |
Ref: Genetic changes of hOGG1 and the activity of oh8Gua glycosylase in colon cancer. PMID: 11239755 Ref: Antioxidant status and lipid peroxidation in colorectal cancer. PMID: 11594700 |
Ref: Use of the human MDR1 promoter for heat-inducible expression of therapeutic genes. PMID: 11857422 Ref: Inhibition of experimental pulmonary metastasis by controlling biodistribution of catalase in mice. PMID: 11992420 Ref: Expression of peroxisome proliferator-activated receptors alpha and gamma in differentiating human colon carcinoma Caco-2 cells. PMID: 12000143 Ref: Bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione (a curcumin analog) ameliorates DMH-induced hepatic oxidative stress during colon carcinogenesis. PMID: 12208119 |
Ref: Sodium selenite, dietary micronutrient, prevents the lymphocyte DNA damage induced by N-nitrosodiethylamine and phenobarbital promoted experimental hepatocarcinogenesis. PMID: 12532333 Ref: Antioxidant potential in esophageal, stomach and colorectal cancers. PMID: 12630007 Ref: Increased activity of catalase in tumor cells overexpressing IGFBP-2. PMID: 14710363 |
Ref: Structurally related antitumor effects of flavanones in vitro and in vivo: involvement of caspase 3 activation, p21 gene expression, and reactive oxygen species production. PMID: 15163544 Ref: Inhibition of experimental hepatic metastasis by targeted delivery of catalase in mice. PMID: 15387371 |
Ref: Lipid peroxidation and antioxidant status in colorectal cancer. PMID: 15637754 Ref: Development of cell-specific targeting systems for drugs and genes. PMID: 15684468 Ref: MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells. PMID: 15817612 Ref: Chemopreventive efficacy of ginger, a naturally occurring anticarcinogen during the initiation, post-initiation stages of 1,2 dimethylhydrazine-induced colon cancer. PMID: 16018877 Ref: Hydrogen peroxide induced oxidative stress damage and antioxidant enzyme response in Caco-2 human colon cells. PMID: 16248583 |
Ref: Improvement of the therapeutic index of anticancer drugs by the superoxide dismutase mimic mangafodipir. PMID: 16478742 Ref: Mechanisms of cardiotoxin lll-induced apoptosis in human colorectal cancer colo205 cells. PMID: 16487259 Ref: Prevention of 1,2-dimethylhydrazine-induced circulatory oxidative stress by bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione during colon carcinogenesis. PMID: 16702625 Ref: Modulatory influence of dietary resveratrol during different phases of 1,2-dimethylhydrazine induced mucosal lipid-peroxidation, antioxidant status and aberrant crypt foci development in rat colon carcinogenesis. PMID: 16733082 Ref: Lipid hydroperoxide induced oxidative stress damage and antioxidant enzyme response in Caco-2 human colon cells. PMID: 16756383 Ref: Dose-response efficacy of caraway (Carum carvi L.) on tissue lipid peroxidation and antioxidant profile in rat colon carcinogenesis. PMID: 16872560 Ref: The role of superoxide anions in the development of distant tumour recurrence. PMID: 17088916 |
Ref: Enhanced oxidative stress and leucocyte activation in neoplastic tissues of the colon. PMID: 17195121 Ref: Effects of garcinol and its derivatives on intestinal cell growth: Inhibitory effects and autoxidation-dependent growth-stimulatory effects. PMID: 17382202 Ref: Fenugreek seeds modulate 1,2-dimethylhydrazine-induced hepatic oxidative stress during colon carcinogenesis. PMID: 17511351 Ref: Gossypol reduction of tumor growth through ROS-dependent mitochondria pathway in human colorectal carcinoma cells. PMID: 17597109 Ref: Antitumor and cytotoxic effects of Phyllanthus polyphyllus on Ehrlich ascites carcinoma and human cancer cell lines. PMID: 17827693 Ref: Chemopreventive effects of nonsteroidal anti-inflammatory drugs on 1,2-dimethylhydrazine-induced colon carcinogenesis in rats. PMID: 20020969 |
Ref: Activated neutrophils induce an hMSH2-dependent G2/M checkpoint arrest and replication errors at a (CA)13-repeat in colon epithelial cells. PMID: 18272544 Ref: Dose-dependent effect of oregano (Origanum vulgare L.) on lipid peroxidation and antioxidant status in 1,2-dimethylhydrazine-induced rat colon carcinogenesis. PMID: 18498716 Ref: Antioxidative effects of nonsteroidal anti-inflammatory drugs during the initiation stages of experimental colon carcinogenesis in rats. PMID: 18540845 Ref: Protective role of luteolin on the status of lipid peroxidation and antioxidant defense against azoxymethane-induced experimental colon carcinogenesis. PMID: 18692983 Ref: Impact of delphinidin on the maintenance of DNA integrity in human colon carcinoma cells. PMID: 18778064 |
Ref: Effect of morin on tissue lipid peroxidation and antioxidant status in 1, 2-dimethylhydrazine induced experimental colon carcinogenesis. PMID: 18496650 Ref: Hesperetin exerts dose dependent chemopreventive effect against 1,2-dimethyl hydrazine induced rat colon carcinogenesis. PMID: 18648748 Ref: Chemopreventive efficacy of pronyl-lysine on lipid peroxidation and antioxidant status in rat colon carcinogenesis. PMID: 19469802 Ref: Resveratrol ameliorates DNA damage, prooxidant and antioxidant imbalance in 1,2-dimethylhydrazine induced rat colon carcinogenesis. PMID: 19523937 Ref: Long-term ingestion of reduced glutathione suppressed an accelerating effect of beef tallow diet on colon carcinogenesis in rats. PMID: 19568688 Ref: Efficacy of the potential chemopreventive agent, hesperetin (citrus flavanone), on 1,2-dimethylhydrazine induced colon carcinogenesis. PMID: 19632289 Ref: Effects of high-fat mixed-lipid diet and exercise on the antioxidant system in skeletal and cardiac muscles of rats with colon carcinoma. PMID: 19904015 Ref: The influence of surgical treatment and red blood cell transfusion on changes in antioxidative and immune system parameters in colorectal cancer patients. PMID: 19996665 Ref: [Activity of selected antioxidant enzymes examination in people with colorectal cancer]. PMID: 20120709 Ref: Genetic Polymorphisms in Genes Related to Oxidative Stress (GSTP1, GSTM1, GSTT1, CAT, MnSOD, MPO, eNOS) and Survival of Rectal Cancer Patients after Radiotherapy. PMID: 20445800 |
Ref: Chemopreventive efficacy of gallic acid, an antioxidant and anticarcinogenic polyphenol, against 1,2-dimethyl hydrazine induced rat colon carcinogenesis. PMID: 19300909 Ref: Differential oxidative stress responses to pure Microcystin-LR and Microcystin-containing and non-containing cyanobacterial crude extracts on Caco-2 cells. PMID: 19825385 Ref: Chemomodulation of the antioxidative enzymes and peroxidative damage in the colon of 1,2-dimethyl hydrazine-induced rats by ellagicacid. PMID: 19827028 Ref: PKG inhibits TCF signaling in colon cancer cells by blocking beta-catenin expression and activating FOXO4. PMID: 20348951 Ref: Involvement of oxidative stress in simvastatin-induced apoptosis of murine CT26 colon carcinoma cells. PMID: 20883752 Ref: [State of the liver antioxidant system and content of matrix metalloproteinase-2 of the large intestine under the effect of maleimide derivative in experimental colorectal carcinogenesis in rats]. PMID: 21516719 |
Ref: Effect of kaempferol on lipid peroxidation and antioxidant status in 1,2-dimethyl hydrazine induced colorectal carcinoma in rats. PMID: 21172346 Ref: Ginsenoside Rh2 induces apoptosis and paraptosis-like cell death in colorectal cancer cells through activation of p53. PMID: 21194832 Ref: Farnesol attenuates 1,2-dimethylhydrazine induced oxidative stress, inflammation and apoptotic responses in the colon of Wistar rats. PMID: 21453689 Ref: Antioxidant enzyme activities of iron-saturated bovine lactoferrin (Fe-bLf) in human gut epithelial cells under oxidative stress. PMID: 21486205 Ref: Anthocyanin-rich blackberry extract suppresses the DNA-damaging properties of topoisomerase I and II poisons in colon carcinoma cells. PMID: 21599019 Ref: Mustard seeds (Sinapis Alba Linn) attenuate azoxymethane-induced colon carcinogenesis. PMID: 21605497 Ref: Effect of myricetin on 1,2 dimethylhydrazine induced rat colon carcinogenesis. PMID: 21699017 Ref: Synthesis, structural and spectroscopic characterization, in vitro cytotoxicity and in vivo activity as free radical scavengers of chlorido(p-cymene) complexes of ruthenium(II) containing N-alkylphenothiazines. PMID: 21741132 Ref: Plasma antioxidant enzymes and clastogenic factors as possible biomarkers of colorectal cancer risk. PMID: 21777595 Ref: Effect of selenium-saturated bovine lactoferrin (Se-bLF) on antioxidant enzyme activities in human gut epithelial cells under oxidative stress. PMID: 21919840 Ref: Strawberry polyphenols attenuate ethanol-induced gastric lesions in rats by activation of antioxidant enzymes and attenuation of MDA increase. PMID: 22016781 Ref: Effect of Cu(II) coordination compounds on the activity of antioxidant enzymes catalase and superoxide dismutase in patients with colorectal cancer. PMID: 22166318 |
Ref: Effects of synbiotic fermentation products on primary chemoprevention in human colon cells. PMID: 21840698 Ref: Role of hesperetin (a natural flavonoid) and its analogue on apoptosis in HT-29 human colon adenocarcinoma cell line--a comparative study. PMID: 22142698 Ref: Lactobacillus plantarum AS1 isolated from south Indian fermented food Kallappam suppress 1,2-dimethyl hydrazine (DMH)-induced colorectal cancer in male Wistar rats. PMID: 22161238 Ref: Oridonin induces apoptosis and senescence by increasing hydrogen peroxide and glutathione depletion in colorectal cancer cells. PMID: 22294162 Ref: beta-sitosterol prevents lipid peroxidation and improves antioxidant status and histoarchitecture in rats with 1,2-dimethylhydrazine-induced colon cancer. PMID: 22353013 Ref: Ellagic acid modulates antioxidant status, ornithine decarboxylase expression, and aberrant crypt foci progression in 1,2-dimethylhydrazine-instigated colon preneoplastic lesions in rats. PMID: 22439659 Ref: Arsenic and chromium in drinking water promote tumorigenesis in a mouse colitis-associated colorectal cancer model and the potential mechanism is ROS-mediated Wnt/beta-catenin signaling pathway. PMID: 22552367 Ref: (1S,2S,3E,7E,11E)-3,7,11,15-Cembratetraen-17,2-olide, a cembrenolide diterpene from soft coral Lobophytum sp., inhibits growth and induces apoptosis in human colon cancer cells through reactive oxygen species generation. PMID: 22791152 Ref: Association of catalase genotype with oxidative stress in the predication of colorectal cancer: modification by epidemiological factors. PMID: 22998821 Ref: The activity of antioxidant enzymes in colorectal adenocarcinoma and corresponding normal mucosa. PMID: 23189274 Ref: Reactive oxygen species mediate Cr(VI)-induced S phase arrest through p53 in human colon cancer cells. PMID: 23216635 |
Ref: Activity of superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase in different stages of colorectal carcinoma. PMID: 23625289 |
Ref: Chemopreventive effect of zingerone against colon carcinogenesis induced by 1,2-dimethylhydrazine in rats. PMID: 23903760 Ref: Dual roles for splice variants of the glucuronidation pathway as regulators of cellular metabolism. PMID: 24141015 Ref: Oxidative stress, cell cycle arrest and differentiation contribute toward the antiproliferative action of BSO and calcitriol on Caco-2 cells. PMID: 24681551 |
Ref: Dietary cocoa protects against colitis-associated cancer by activating the Nrf2/Keap1 pathway. PMID: 25545372 Ref: Hydrogen peroxide generated by xanthine/xanthine oxidase system represses the proliferation of colorectal cancer cell line Caco-2. PMID: 25678748 Ref: Manganese superoxide dismutase (SOD2/MnSOD)/catalase and SOD2/GPx1 ratios as biomarkers for tumor progression and metastasis in prostate, colon, and lung cancer. PMID: 25866291 Ref: Effects of ghrelin, leptin and melatonin on the levels of reactive oxygen species, antioxidant enzyme activity and viability of the HCT 116 human colorectal carcinoma cell line. PMID: 25873273 Ref: Carvacrol exhibits anti-oxidant and anti-inflammatory effects against 1, 2-dimethyl hydrazine plus dextran sodium sulfate induced inflammation associated carcinogenicity in the colon of Fischer 344 rats. PMID: 25881504 Ref: Chemoprevention of Colonic Aberrant Crypt Foci by Novel Schiff Based Dichlorido(4-Methoxy-2-{[2-(Piperazin-4-Ium-1-Yl)Ethyl]Iminomethyl}Phenolate)Cd Complex in Azoxymethane-Induced Colorectal Cancer in Rats. PMID: 26201720 Ref: Chemopreventive effects of Strobilanthes crispus leaf extract on azoxymethane-induced aberrant crypt foci in rat colon. PMID: 26307342 Ref: p-Methoxycinnamic acid, an active phenylpropanoid induces mitochondrial mediated apoptosis in HCT-116 human colon adenocarcinoma cell line. PMID: 26546748 |
Ref: Radioprotection of 1,2-dimethylhydrazine-initiated colon cancer in rats using low-dose gamma rays by modulating multidrug resistance-1, cytokeratin 20, and beta-catenin expression. PMID: 25926526 Ref: Antioxidant, immunomodulatory and antiproliferative effects of gelatin hydrolysate from unicorn leatherjacket skin. PMID: 26493634 Ref: The Comparison of Biodistribution, Efficacy and Toxicity of Two PEGylated Liposomal Doxorubicin Formulations in Mice Bearing C-26 Colon Carcinoma: a Preclinical Study. PMID: 27022719 Ref: Columbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells. PMID: 27098859 Ref: Chemopreventive effect of carvacrol on 1,2-dimethylhydrazine induced experimental colon carcinogenesis. PMID: 27461646 Ref: Sambar, an Indian Dish Prevents the Development of Dimethyl Hydrazine-Induced Colon Cancer: A Preclinical Study. PMID: 27761072 Ref: Red Seaweed (Hypnea Bryodies and Melanothamnus Somalensis) Extracts Counteracting Azoxymethane-Induced Hepatotoxicity in Rats PMID: 28122436 |
Ref: Chemopreventive potential of in vitro fermented nuts in LT97 colon adenoma and primary epithelial colon cells. PMID: 27996158 Ref: cGMP Signaling Increases Antioxidant Gene Expression by Activating Forkhead Box O3A in the Colon Epithelium. PMID: 27998725 Ref: Hepatoprotective Effect of Carboxymethyl Pachyman in Fluorouracil-Treated CT26-Bearing Mice. PMID: 28481246 Ref: Molecular Basis of Alcohol-Related Gastric and Colon Cancer. PMID: 28538665 Ref: Effects of moderate alcohol consumption on gene expression related to colonic inflammation and antioxidant enzymes in rats. PMID: 28599714 Ref: Evaluation of in vitro cytotoxicity, biocompatibility, and changes in the expression of apoptosis regulatory proteins induced by cerium oxide nanocrystals. PMID: 28634498 Ref: Genetic polymorphisms of superoxide dismutase-1 A251G and catalase C-262T with the risk of colorectal cancer. PMID: 28775994 Ref: Luteolin induces apoptotic cell death via antioxidant activity in human colon cancer cells. PMID: 28791416 Ref: Anticarcinogenic activity of Muntingia calabura leaves methanol extract against the azoxymethane-induced colon cancer in rats involved modulation of the colonic antioxidant system partly by flavonoids. PMID: 28872373 Ref: Inhibitory effect of hyperoside isolated from Zanthoxylum bungeanum leaves on SW620 human colorectal cancer cells via induction of the p53 signaling pathway and apoptosis. PMID: 29067453 Ref: In vitro-fermented raw and roasted walnuts induce expression of CAT and GSTT2 genes, growth inhibition, and apoptosis in LT97 colon adenoma cells. PMID: 29241580 Ref: Chemopreventive Potential of Raw and Roasted Pistachios Regarding Colon Carcinogenesis. PMID: 29258268 |
Ref: Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells. PMID: 28886484 Ref: Chemoprevention by Probiotics During 1,2-Dimethylhydrazine-Induced Colon Carcinogenesis in Rats. PMID: 29427224 Ref: Aberrant crypt foci are regionally affected by zinc treatment in a 1,2-dimethylhydrazine induced colon carcinogenesis model. PMID: 29544804 Ref: Phytosomal curcumin inhibits tumor growth in colitis-associated colorectal cancer. PMID: 29737515 Ref: Supra-physiological concentration of glyoxylate inhibits proliferation of human colon cancer cells through oxidative stress. PMID: 29852189 Ref: Implications of Isoprostanes and Matrix Metalloproteinase-7 Having Potential Role in the Development of Colorectal Cancer in Males. PMID: 29930913 Ref: Design, Synthesis and Antiproliferative Activities of Oxidative Stress Inducers Based on 2-Styryl-3,5-dihydro-4H-imidazol-4-one Scaffold. PMID: 30047515 Ref: Manuka honey synergistically enhances the chemopreventive effect of 5-fluorouracil on human colon cancer cells by inducing oxidative stress and apoptosis, altering metabolic phenotypes and suppressing metastasis ability. PMID: 30056083 Ref: Crocin synergistically enhances the antiproliferative activity of 5-flurouracil through Wnt/PI3K pathway in a mouse model of colitis-associated colorectal cancer. PMID: 30129057 Ref: Non-tumor adjacent tissue of advanced stage from CRC shows activated antioxidant response. PMID: 30130568 Ref: Effects of Grape Juice in Superoxide Dismutase and Catalase in Colorectal Cancer Carcinogenesis Induced by Azoxymethane PMID: 30362310 |