Primary Site >> Colorectal Cancer
Gene >> CASR
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Dietary calcium and growth modulation of human colon cancer cells: role of the extracellular calcium-sensing receptor. PMID: 10917132 |
Ref: Calcium-sensing receptor A986S polymorphism in human rectal cancer. PMID: 12018449 |
Ref: Extracellular calcium and calcium sensing receptor function in human colon carcinomas: promotion of E-cadherin expression and suppression of beta-catenin/TCF activation. PMID: 12517779 Ref: Molecular and functional characterization of the extracellular calcium-sensing receptor in human colon cancer cells. PMID: 12899245 |
Ref: The role of the calcium-sensing receptor in cancer. PMID: 15200153 Ref: Relationship between serum calcium and CA 19-9 levels in colorectal cancer. PMID: 15222030 Ref: [Significance of serum calcium levels in colorectal cancer]. PMID: 15382619 Ref: Association of genetic variants in the calcium-sensing receptor with risk of colorectal adenoma. PMID: 15598778 |
Ref: Calcium sensing receptor in human colon carcinoma: interaction with Ca(2+) and 1,25-dihydroxyvitamin D(3). PMID: 15695391 Ref: Upregulation of calcium-sensing receptor and mitogen-activated protein kinase signalling in the regulation of growth and differentiation in colon carcinoma. PMID: 16278666 |
Ref: Role of calcium and other trace elements in the gastrointestinal physiology. PMID: 16718844 Ref: Roles for the calcium sensing receptor in primary and metastatic cancer. PMID: 16765016 |
Ref: Wnt5a secretion stimulated by the extracellular calcium-sensing receptor inhibits defective Wnt signaling in colon cancer cells. PMID: 17463182 Ref: Regulation of E-cadherin and beta-catenin by Ca2+ in colon carcinoma is dependent on calcium-sensing receptor expression and function. PMID: 17557293 |
Ref: The role of calcium-sensing receptor and signalling pathways in the pathophysiology in two in vitro models of malignant hypercalcemia: the rat rice H-500 Leydig testis cancer and prostate cancer (PC-3) cells. Expression and regulation of pituitary tumor t PMID: 18321443 Ref: Enterotoxin preconditioning restores calcium-sensing receptor-mediated cytostasis in colon cancer cells. PMID: 18566015 Ref: Genetic variation in calcium-sensing receptor and risk for colon cancer. PMID: 18843020 Ref: Effects of the lactase 13910 C/T and calcium-sensor receptor A986S G/T gene polymorphisms on the incidence and recurrence of colorectal cancer in Hungarian population. PMID: 18980667 |
Ref: Calcium, calcium-sensing receptor and colon cancer. PMID: 18725175 Ref: Calcium-sensing receptor in cancer: good cop or bad cop? PMID: 19011996 Ref: The role of the calcium-sensing receptor in the development and progression of cancer. PMID: 19237714 Ref: Vitamin D receptor and calcium sensing receptor polymorphisms and the risk of colorectal cancer in European populations. PMID: 19706842 |
Ref: Vitamin D mediates its action in human colon carcinoma cells in a calcium-sensing receptor-dependent manner: downregulates malignant cell behavior and the expression of thymidylate synthase and survivin and promotes cellular sensitivity to 5-FU. PMID: 19621386 Ref: Effects of potential calcium sensing receptor inducers on promoting chemosensitivity of human colon carcinoma cells. PMID: 20428782 Ref: Genetic variation in the retinoid X receptor and calcium-sensing receptor and risk of colorectal cancer in the Colon Cancer Family Registry. PMID: 20558521 |
Ref: A short primer on the calcium sensing receptor: an important cog in the colon cancer wheel? PMID: 20556514 Ref: A randomized clinical trial of the effects of supplemental calcium and vitamin D3 on markers of their metabolism in normal mucosa of colorectal adenoma patients. PMID: 21084270 Ref: Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis. PMID: 21317879 Ref: Nifedipine synergizes with calcium in activating the calcium sensing receptor, suppressing the expression of thymidylate synthase and survivin and promoting sensitivity to fluorouracil in human colon carcinoma cells. PMID: 21374737 Ref: Calcium, calcium-sensing receptor and growth control in the colonic mucosa. PMID: 21472691 Ref: Extracellular Calcium-Sensing Receptor Inhibition of Intestinal EpithelialTNF Signaling Requires CaSR-Mediated Wnt5a/Ror2 Interaction. PMID: 21603229 Ref: Thermostable direct hemolysin downregulates human colon carcinoma cell proliferation with the involvement of E-cadherin, and beta-catenin/Tcf-4 signaling. PMID: 21625458 |
Ref: Review article: loss of the calcium-sensing receptor in colonic epithelium is a key event in the pathogenesis of colon cancer. PMID: 21723793 Ref: Prediagnostic 25-hydroxyvitamin D, VDR and CASR polymorphisms, and survival in patients with colorectal cancer in western European ppulations. PMID: 22278364 Ref: The role of the calcium-sensing receptor in human disease. PMID: 22503956 Ref: Calcium sensing receptor modulation for cancer therapy. PMID: 23098435 |
Ref: Isolation and characterization of calcium sensing receptor null cells: a highly malignant and drug resistant phenotype of colon cancer. PMID: 23055106 Ref: Calcium sensing receptor signalling in physiology and cancer. PMID: 23267858 Ref: Extracellular calcium-sensing receptor/PTH knockout mice colons have increased Wnt/beta-catenin signaling, reduced non-canonical Wnt signaling, and increased susceptibility to azoxymethane-induced aberrant crypt foci. PMID: 23545937 Ref: Association between CASR polymorphisms, calcium intake, and colorectal cancer risk. PMID: 23555732 Ref: Cellular responses to TGFbeta and TGFbeta receptor expression in human colonic epithelial cells require CaSR expression and function. PMID: 23639611 Ref: Induction of CaSR expression circumvents the molecular features of malignant CaSR null colon cancer cells. PMID: 23674327 Ref: Role of calcium sensing receptor (CaSR) in tumorigenesis. PMID: 23856272 Ref: Patient and primary care provider experience using a family health history collection, risk stratification, and clinical decision support tool: a type 2 hybrid controlled implementation-effectiveness trial. PMID: 23915256 Ref: The genomic medicine model: an integrated approach to implementation of family health history in primary care. PMID: 29768748 |
Ref: Regulation of the calcium-sensing receptor expression by 1,25-dihydroxyvitamin D3, interleukin-6, and tumor necrosis factor alpha in colon cancer cells. PMID: 24176760 Ref: Calcium-sensing receptor silencing in colorectal cancer is associated with promoter hypermethylation and loss of acetylation on histone 3. PMID: 24691920 Ref: Roles of the calcium sensing receptor in digestive physiology and pathophysiology (review). PMID: 25069966 Ref: Parathyroid hormone gene rs6256 and calcium sensing receptor gene rs1801725 variants are not associated with susceptibility to colorectal cancer in Iran. PMID: 25124570 |
Ref: Effects of supplemental vitamin D and calcium on normal colon tissue and circulating biomarkers of risk for colorectal neoplasms. PMID: 25597952 Ref: The calcium-sensing receptor suppresses epithelial-to-mesenchymal transition and stem cell- like phenotype in the colon. PMID: 25879211 Ref: Induction of calcium sensing receptor in human colon cancer cells by calcium, vitamin D and aquamin: Promotion of a more differentiated, less malignant and indolent phenotype. PMID: 26076051 Ref: [Bone and Nutrition. A prospect of calcium sensing receptor]. PMID: 26119316 Ref: Familial risk for lifestyle-related chronic diseases: can family health history be used as a motivational tool to promote health behaviour in young adults? PMID: 26177521 Ref: A genetic polymorphism (rs17251221) in the calcium-sensing receptor is associated with ovarian cancer susceptibility. PMID: 26252839 |
Ref: Active vitamin D potentiates the anti-neoplastic effects of calcium in the colon: A cross talk through the calcium-sensing receptor. PMID: 25758239 Ref: miR-135b- and miR-146b-dependent silencing of calcium-sensing receptor expression in colorectal tumors. PMID: 26178670 Ref: Genetic polymorphisms of CASR and cancer risk: evidence from meta-analysis and HuGE review. PMID: 26929638 Ref: Calcium-Sensing Receptor Gene: Regulation of Expression. PMID: 27679579 Ref: The Calcium-Sensing Receptor in Health and Disease. PMID: 27692178 Ref: Alanine to Serine Variant at Position 986 of Calcium Sensing Receptor and Colorectal Cancer Risk. PMID: 27761213 Ref: Cross Talk between the Calcium-Sensing Receptor and the Vitamin D System in Prevention of Cancer. PMID: 27803671 |
Ref: Expression profiling of colorectal cancer cells reveals inhibition of DNA replication licensing by extracellular calcium. PMID: 28161520 Ref: Rectal Cancer in a Patient with Bartter Syndrome: A Case Report. PMID: 28498361 Ref: Vitamin D receptor and calcium-sensing receptor polymorphisms and colorectal cancer survival in the Newfoundland population. PMID: 28765616 |
Ref: Calcium intake and risk of colorectal cancer according to expression status of calcium-sensing receptor (CASR). PMID: 28676564 Ref: Calcium-sensing receptor in colorectal inflammation and cancer: Current insights and future perspectives. PMID: 30271078 |