Primary Site >> Stomach Cancer
Gene >> CASP8
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Ref: Characterization of glycosylphosphatidylinositol-linked molecule CD55/decay-accelerating factor as the receptor for antibody SC-1-induced apoptosis. PMID: 10537313 |
Ref: 2-Methoxyestradiol-induced caspase-3 activation and apoptosis occurs through G(2)/M arrest dependent and independent pathways in gastric carcinoma cells. PMID: 11505393 Ref: Adenovirus-mediated transfection of caspase-8 augments anoikis and inhibits peritoneal dissemination of human gastric carcinoma cells. PMID: 11585725 |
Ref: Analysis of the gene-expression profile regarding the progression of human gastric carcinoma. PMID: 11821786 Ref: Inactivating mutations of the caspase-10 gene in gastric cancer. PMID: 11973654 Ref: Profiling of differentially expressed genes in human gastric carcinoma by cDNA expression array. PMID: 12174360 Ref: Roles of Fas signaling pathway in vitamin E succinate-induced apoptosis in human gastric cancer SGC-7901 cells. PMID: 12439910 Ref: Stomach cancer highly expresses both initiator and effector caspases; an immunohistochemical study. PMID: 12588423 |
Ref: [The expression and activity of caspase-8 in the process of vitamin E succinate-induced apoptosis in human gastric carcinoma SGC-7901 cells]. PMID: 12839663 Ref: Upregulation of FLIP(S) by Akt, a possible inhibition mechanism of TRAIL-induced apoptosis in human gastric cancers. PMID: 14662022 Ref: Differential expression of intracellular apoptotic signaling molecules in tumor and tumor-infiltrating lymphocytes during development of invasion and/or metastasis of gastric carcinoma. PMID: 14714615 |
Ref: Transforming growth factor-beta 1 induces apoptosis through Fas ligand-independent activation of the Fas death pathway in human gastric SNU-620 carcinoma cells. PMID: 14595120 Ref: [Inducement of FLICE inhibitory protein antisense oligonucleotides on apoptosis of human gastric cancer cell line BGC823]. PMID: 15566642 |
Ref: Activation of the caspase-8/Bid and Bax pathways in aspirin-induced apoptosis in gastric cancer. PMID: 15579484 Ref: CASPASE-8 gene is inactivated by somatic mutations in gastric carcinomas. PMID: 15705878 Ref: Combination of S-allylcysteine and lycopene induces apoptosis by modulating Bcl-2, Bax, Bim and caspases during experimental gastric carcinogenesis. PMID: 16030430 Ref: Caspase-8 is scarcely silenced and its activity is well correlated with the anticancer effect of tumor necrosis factor-related apoptosis-inducing ligand in gastric cancer cells. PMID: 16211292 |
Ref: Induction of apoptosis and cell cycle arrest by a specific c-Jun NH2-terminal kinase (JNK) inhibitor, SP-600125, in gastrointestinal cancers. PMID: 16337741 Ref: Mutational analysis of the CASP6 gene in colorectal and gastric carcinomas. PMID: 16948818 |
Ref: Helicobacter pylori-induced apoptosis in T cells is mediated by the mitochondrial pathway independent of death receptors. PMID: 17217377 Ref: [Effects of Chinese herbal recipe Weichang'an in inducing apoptosis and related gene expression in human gastric cancer grafted onto nude mice]. PMID: 17498489 Ref: Plaunotol induces apoptosis of gastric cancer cells. PMID: 17691055 Ref: [Effect of valproate acid sodium on apoptosis of human gastric cancer cells and its mechanism study]. PMID: 17851791 Ref: Expression of c-FLIP in gastric cancer and its relation to tumor cell proliferation and apoptosis. PMID: 18309685 |
Ref: Induction of G2/M arrest and apoptosis by water extract of Strychni Semen in human gastric carcinoma AGS cells. PMID: 18446845 Ref: Promoter methylation of cancer-related genes in gastric carcinoma. PMID: 18566573 Ref: Mitochondrial transmembrane potential and reactive oxygen species generation regulate the enhanced effect of CCCP on TRAIL-induced SNU-638 cell apoptosis. PMID: 18628592 |
Ref: Mechanism of apoptosis induced by a newly synthesized derivative of macrosphelides with a thiazole side chain. PMID: 19014919 Ref: Inhibition of gastric cancer cell growth by arginine: molecular mechanisms of action. PMID: 19036482 Ref: Methylation of protocadherin 10, a novel tumor suppressor, is associated with poor prognosis in patients with gastric cancer. PMID: 19084528 Ref: Cell growth regulation through apoptosis by activin in human gastric cancer SNU-16 cell lines. PMID: 19148527 Ref: Lack of death receptor 4 (DR4) expression through gene promoter methylation in gastric carcinoma. PMID: 19350268 Ref: A novel histone deacetylase inhibitor, CG0006, induces cell death through both extrinsic and intrinsic apoptotic pathways. PMID: 19644355 |
Ref: Cimetidine induces apoptosis in gastric cancer cells in vitro and inhibits tumor growth in vivo. PMID: 20127008 Ref: Reovirus infection induces apoptosis of TRAIL-resistant gastric cancer cells by down-regulation of Akt activation. PMID: 20198349 Ref: Activation of ASC induces apoptosis or necrosis, depending on the cell type, and causes tumor eradication. PMID: 20500518 Ref: Programmed cell death 4 (PDCD4) mediates the sensitivity of gastric cancer cells to TRAIL-induced apoptosis by down-regulation of FLIP expression. PMID: 20595005 |
Ref: The G1 phase arrest and apoptosis by intrinsic pathway induced by valproic acid inhibit proliferation of BGC-823 gastric carcinoma cells. PMID: 21113745 Ref: LY294002 potentiates the anti-cancer effect of oxaliplatin for gastric cancer via death receptor pathway. PMID: 21245990 Ref: Lipid raft-dependent death receptor 5 (DR5) expression and activation are critical for ursodeoxycholic acid-induced apoptosis in gastric cancer cells. PMID: 21362627 Ref: Caspase 8 and caspase 9 gene polymorphisms and susceptibility to gastric cancer. PMID: 21461653 Ref: Alpha-tocopheryl succinate enhances doxorubicin-induced apoptosis in human gastric cancer cells via promotion of doxorubicin influx and suppression of doxorubicin efflux. PMID: 21536373 Ref: Chestnut extract induces apoptosis in AGS human gastric cancer cells. PMID: 21779520 Ref: The extrinsic apoptotic signaling pathway in gastric adenocarcinomas assessed by tissue microarray. PMID: 21856093 Ref: [Cisplatin enhances TRAIL-induced apoptosis in gastric cancer cells through clustering death receptor 4 into lipid rafts]. PMID: 22093622 Ref: Molecular mechanisms of celery seed extract induced apoptosis via s phase cell cycle arrest in the BGC-823 human stomach cancer cell line. PMID: 22320960 Ref: A six-nucleotide deletion polymorphism in the casp8 promoter is associated with reduced risk of esophageal and gastric cancers in Kashmir valley. PMID: 22345985 |
Ref: Epigenetic inactivation of BCL6B, a novel functional tumour suppressor for gastric cancer, is associated with poor survival. PMID: 21917650 Ref: Homeobox D10 gene, a candidate tumor suppressor, is downregulated through promoter hypermethylation and associated with gastric carcinogenesis. PMID: 22160393 Ref: Gastric cancer cell supernatant causes apoptosis and fibrosis in the peritoneal tissues and results in an environment favorable to peritoneal metastases, in vitro and in vivo. PMID: 22520554 Ref: Resistance to TRAIL is mediated by DARPP-32 in gastric cancer. PMID: 22589394 Ref: Cbl-b-dependent degradation of FLIP(L) is involved in ATO-induced autophagy in leukemic K562 and gastric cancer cells. PMID: 22884570 Ref: Ethanol extract of paeonia suffruticosa Andrews (PSE) induced AGS human gastric cancer cell apoptosis via fas-dependent apoptosis and MDM2-p53 pathways. PMID: 22963678 Ref: siRNA targeting decoy receptor 3 enhances the sensitivity of gastric carcinoma cells to 5-fluorouracil. PMID: 23181119 |
Ref: miR-106a is frequently upregulated in gastric cancer and inhibits the extrinsic apoptotic pathway by targeting FAS. PMID: 22431000 Ref: SERPINA3K induces apoptosis in human colorectal cancer cells via activating the Fas/FasL/caspase-8 signaling pathway. PMID: 23615374 Ref: 1-[2-(2-Methoxyphenylamino)ethylamino]-3-(naphthalene-1-yloxy)propan-2-ol as a potential anticancer drug. PMID: 23817168 Ref: Sodium nitroprusside (SNP) sensitizes human gastric cancer cells to TRAIL-induced apoptosis. PMID: 23871247 Ref: Cetuximab enhances TRAIL-induced gastric cancer cell apoptosis by promoting DISC formation in lipid rafts. PMID: 23973713 Ref: Raddeanin A induces human gastric cancer cells apoptosis and inhibits their invasion in vitro. PMID: 23988447 Ref: KLF4 expression and apoptosis-related markers in gastric cancer. PMID: 24065485 Ref: A C 21 -Steroidal Glycoside Isolated from the Roots of Cynanchum auriculatum Induces Cell Cycle Arrest and Apoptosis in Human Gastric Cancer SGC-7901 Cells. PMID: 24454488 |
Ref: Differential cytotoxicity and particle action of hydroxyapatite nanoparticles in human cancer cells. PMID: 23614636 Ref: Genetic variants in fas signaling pathway genes and risk of gastric cancer. PMID: 23921907 Ref: Combination therapy of anti-cancer bioactive peptide with Cisplatin decreases chemotherapy dosing and toxicity to improve the quality of life in xenograft nude mice bearing human gastric cancer. PMID: 24507386 Ref: Functional polymorphisms in apoptosis pathway genes and survival in patients with gastric cancer. PMID: 24535941 Ref: 1,25-Dihydroxyvitamin D(3) and cisplatin synergistically induce apoptosis and cell cycle arrest in gastric cancer cells. PMID: 24573222 Ref: Tangeretin, a citrus polymethoxyflavonoid, induces apoptosis of human gastric cancer AGS cells through extrinsic and intrinsic signaling pathways. PMID: 24573532 Ref: Helicobacter pylori sensitizes TNF-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human gastric epithelial cells through regulation of FLIP. PMID: 24603337 Ref: Thioridazine, an antipsychotic drug, elicits potent antitumor effects in gastric cancer. PMID: 24604290 Ref: Celecoxib regulates apoptosis and autophagy via the PI3K/Akt signaling pathway in SGC-7901 gastric cancer cells. PMID: 24676394 Ref: A novel derivative of quinazoline, WYK431 induces G2/M phase arrest and apoptosis in human gastric cancer BGC823 cells through the PI3K/Akt pathway. PMID: 24859921 Ref: Anti-apoptotic and apoptotic pathway analysis of arsenic trioxideinduced apoptosis in human gastric cancer SGC-7901 cells. PMID: 24969414 Ref: The lectin BJcuL induces apoptosis through TRAIL expression, caspase cascade activation and mitochondrial membrane permeability in a human colon adenocarcinoma cell line. PMID: 25194746 Ref: Anthraquinone G503 induces apoptosis in gastric cancer cells through the mitochondrial pathway. PMID: 25268882 Ref: Alkaloids from beach spider lily (Hymenocallis littoralis) induce apoptosis of HepG-2 cells by the fas-signaling pathway. PMID: 25422219 Ref: Tanshinone IIA inhibits gastric carcinoma AGS cells through increasing p-p38, p-JNK and p53 but reducing p-ERK, CDC2 and cyclin B1 expression. PMID: 25503137 |
Ref: The newly synthesized anticancer drug HUHS1015 is useful for treatment of human gastric cancer. PMID: 25567349 Ref: FV-429 Induced Apoptosis Through ROS-Mediated ERK2 Nuclear Translocation and p53 Activation in Gastric Cancer Cells. PMID: 25650185 Ref: Hericium erinaceus polysaccharide-protein HEG-5 inhibits SGC-7901 cell growth via cell cycle arrest and apoptosis. PMID: 25703932 Ref: Genotoxic and cytostatic effects of 6-pentadecyl salicylic anacardic acid in transformed cell lines and peripheral blood mononuclear cells. PMID: 25726174 Ref: Genetic variation and gastric cancer risk: a field synopsis and meta-analysis. PMID: 25731870 Ref: Notch 1 promotes cisplatin-resistant gastric cancer formation by upregulating lncRNA AK022798 expression. PMID: 25763542 Ref: Antiproliferative activity of rosamultic acid is associated with induction of apoptosis, cell cycle arrest, inhibition of cell migration and caspase activation in human gastric cancer (SGC-7901) cells. PMID: 26220626 Ref: [Effect of Paridis Rhizoma total saponins on apoptosis of human gastric cancer cell MKN-45 and Fas/FasL signaling pathway]. PMID: 26281566 Ref: [Changes in the number of copies of genetic loci in gastric cancer]. PMID: 26299866 Ref: Induction of Apoptosis by Eugenol and Capsaicin in Human Gastric Cancer AGS Cells--Elucidating the Role of p53. PMID: 26434906 Ref: beta-Asarone inhibits gastric cancer cell proliferation. PMID: 26502896 Ref: Novel mechanism of harmaline on inducing G2/M cell cycle arrest and apoptosis by up-regulating Fas/FasL in SGC-7901 cells. PMID: 26678950 |
Ref: Sulforaphene promotes Bax/Bcl2, MAPK-dependent human gastric cancer AGS cells apoptosis and inhibits migration via EGFR, p-ERK1/2 down-regulation. PMID: 26612919 Ref: Curcumin Enhances the Effects of 5-Fluorouracil and Oxaliplatin in Inducing Gastric Cancer Cell Apoptosis Both In Vitro and In Vivo. PMID: 26802648 Ref: Enhancement of Drug Sensitivity by Knockdown of HIF-1alpha in Gastric Carcinoma Cells. PMID: 26931435 Ref: Melittin induces human gastric cancer cell apoptosis via activation of mitochondrial pathway. PMID: 27003995 Ref: Apoptotic Cell Death Induced by ofLBP6A, Lipopolysaccharide Binding Protein Model Peptide, Derived from Paralichthy olivaceus on MKN-28 Cells. PMID: 27009854 Ref: Grifola frondosa Glycoprotein GFG-3a Arrests S phase, Alters Proteome, and Induces Apoptosis in Human Gastric Cancer Cells. PMID: 27040446 Ref: Epigenetic silencing of tumor suppressor long non-coding RNA BM742401 in chronic lymphocytic leukemia. PMID: 27689399 Ref: Kayeassamin A Isolated from the Flower of Mammea siamensis Triggers Apoptosis by Activating Caspase-3/-8 in HL-60 Human Leukemia Cells. PMID: 27695262 Ref: [Apoptosis mechanism of taxol combined with resveratrol on human laryngeal carcinoma Hep-2 cells]. PMID: 28868867 Ref: Curcumin Enhances the Effects of 5-Fluorouracil and Oxaliplatin in Inducing Gastric Cancer Cell Apoptosis Both In Vitro and In Vivo. PMID: 29021018 Ref: [Study on Mulberry Anthocyanins Induced Autophagy and Apoptosis of Human Gastric Cancer SGC-7901 Cell Autophagy]. PMID: 30133211 |
Ref: Effect of PUFAs Oral Administration on the Amount of Apoptotic Caspases Enzymes in Gastric Cancer Patients Undergoing Chemotherapy. PMID: 27198984 Ref: Fas expression is downregulated in gastric cancer. PMID: 28000850 Ref: SLPI promotes the gastric cancer growth and metastasis by regulating the expression of P53, Bcl-2 and Caspase-8. PMID: 28429358 Ref: Long Noncoding RNA AFAP1-AS1 Promotes Cell Proliferation and Apoptosis of Gastric Cancer Cells via PTEN/p-AKT Pathway. PMID: 28451917 Ref: Functional foods and their role in cancer prevention and health promotion: a comprehensive review. PMID: 28469951 Ref: Shared susceptibility loci at 2q33 region for lung and esophageal cancers in high-incidence areas of esophageal cancer in northern China. PMID: 28542283 Ref: Long Noncoding RNA H19/miR-675 Axis Promotes Gastric Cancer via FADD/Caspase 8/Caspase 3 Signaling Pathway. PMID: 28848149 Ref: Synergistic anticancer effect of curcumin and chemotherapy regimen FP in human gastric cancer MGC-803 cells. PMID: 28927092 Ref: In vitro effects and the related molecular mechanism of galangin and quercetin on human gastric cancer cell line (SGC-7901). PMID: 29039326 Ref: Analysis of 12 variants in the development of gastric and colorectal cancers. PMID: 29358861 |
Ref: Euphorbia lunulata extract acts on multidrug resistant gastric cancer cells to inhibit cell proliferation, migration and invasion, arrest cell cycle progression, and induce apoptosis. PMID: 28811220 Ref: VDR independent induction of acid-sphingomyelinase by 1,23(OH)2 D3 in gastric cancer cells: Impact on apoptosis and cell morphology. PMID: 29158006 Ref: miR-200a enhances TRAIL-induced apoptosis in gastric cancer cells by targeting A20. PMID: 29274253 Ref: Inflammasome Adaptor ASC Suppresses Apoptosis of Gastric Cancer Cells by an IL18-Mediated Inflammation-Independent Mechanism. PMID: 29282220 Ref: Irigenin sensitizes TRAIL-induced apoptosis via enhancing pro-apoptotic molecules in gastric cancer cells. PMID: 29305260 Ref: The molecular mechanism of anticancer action of novel octahydropyrazino[2,1-a:5,4-a']diisoquinoline derivatives in human gastric cancer cells. PMID: 29549610 Ref: Isolation and identification of three new chromones from the leaves of Pimenta dioica with cytotoxic, oestrogenic and anti-oestrogenic effects. PMID: 29564971 Ref: Prognostic significance of microsatellite instabilityassociated pathways and genes in gastric cancer. PMID: 29717769 Ref: Dasatinib promotes TRAIL-mediated apoptosis by upregulating CHOP-dependent death receptor 5 in gastric cancer. PMID: 29744288 Ref: Detecting promoter methylation pattern of apoptotic genes Apaf1 and Caspase8 in gastric carcinoma patients undergoing chemotherapy. PMID: 29755768 Ref: Deubiquitinylase USP47 Promotes RelA Phosphorylation and Survival in Gastric Cancer Cells. PMID: 29786670 Ref: Anti-tumor mechanism of IL-21 used alone and in combination with 5-fluorouracil in vitro on human gastric cancer cells. PMID: 29921390 Ref: beta-elemene increases the sensitivity of gastric cancer cells to TRAIL by promoting the formation of DISC in lipid rafts. PMID: 29957841 Ref: Co-expression of caspase-3 or caspase-8 with galanin in the human stomach section affected by carcinoma. PMID: 30019295 Ref: A meta-analysis of caspase-8 -652 6N del polymorphism and digestive tract cancer risk. PMID: 30057371 Ref: Resveratrol induces apoptosis in SGC-7901 gastric cancer cells. PMID: 30127883 Ref: Celastrus Orbiculatus Extract Potentiates The Sensitivity Of Cisplatin Via Caspase-Depenent Apoptosis In Gastric Cancer. PMID: 30205802 Ref: Long noncoding RNA Z38 promotes cell proliferation and metastasis and inhibits cell apoptosis in human gastric cancer. PMID: 30333877 |