Primary Site >> Esophagus Cancer
Gene >> CASP3
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Ref: Caspase activation and changes in Bcl-2 family member protein expression associated with E2F-1-mediated apoptosis in human esophageal cancer cells. PMID: 10778992 |
Ref: Induction of apoptosis by cyclo-oxygenase-2 inhibitor NS398 through a cytochrome C-dependent pathway in esophageal cancer cells. PMID: 11410869 Ref: Human esophageal cancer cell death mediated by apoptosis-inducing nucleosides from CD57+HLA-DRbright natural suppressor cell line. PMID: 11713594 |
Ref: Isolation and characterization of a novel gene, hRFI, preferentially expressed in esophageal cancer. PMID: 12118383 Ref: Specific ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in human esophageal cancer cells. PMID: 12402299 |
Ref: Somatic mutations of CASP3 gene in human cancers. PMID: 15127291 Ref: Selective inhibition of survival signal transduction pathways enhanced radiosensitivity in human esophageal cancer cell lines in vitro. PMID: 15161032 |
Ref: ZD1839 (Gefitinib, 'Iressa'), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma. PMID: 16023108 Ref: Bile salts inhibit growth and induce apoptosis of human esophageal cancer cell line. PMID: 16127738 Ref: Dual effects of 8-Br-cAMP on differentiation and apoptosis of human esophageal cancer cell line Eca-109. PMID: 16425431 |
Ref: Enhanced sensitivity to chemotherapy in esophageal cancer through inhibition of NF-kappaB. PMID: 16337965 Ref: Enhancement of Apo2L/TRAIL-mediated cytotoxicity in esophageal cancer cells by cisplatin. PMID: 17172403 |
Ref: Immunological protection against HPV16 E7-expressing human esophageal cancer cell challenge by a novel HPV16-E6/E7 fusion protein based-vaccine in a Hu-PBL-SCID mouse model. PMID: 17202676 Ref: Pretreatment with insulin enhances anticancer functions of 5-fluorouracil in human esophageal and colonic cancer cells. PMID: 17439729 Ref: IGFBP-3 regulates esophageal tumor growth through IGF-dependent and independent mechanisms. PMID: 17457048 Ref: Claudins 1, 3, 4, 5 and 7 in esophageal cancer: loss of claudin 3 and 4 expression is associated with metastatic behavior. PMID: 17614851 |
Ref: G-rich oligonucleotides alter cell cycle progression and induce apoptosis specifically in OE19 esophageal tumor cells. PMID: 18321162 Ref: Synergistic apoptotic effects of taurolidine and TRAIL on squamous carcinoma cells of the esophagus. PMID: 18497982 |
Ref: Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells. PMID: 19534809 Ref: [In vivo antitumor effect of canstatin gene on human esophageal carcinoma xenografts in nude mice]. PMID: 19622292 Ref: [Mechanism of photodynamic therapy against human esophageal carcinoma xenografts in nude mice]. PMID: 19923072 |
Ref: Upregulation of caspase-3 expression in esophageal cancer correlates with favorable prognosis: an immunohistochemical study from a high incidence area in northern China. PMID: 20113321 Ref: Loss of p53, rather than beta-catenin overexpression, induces survivin-mediated resistance to apoptosis in an esophageal cancer cell line. PMID: 20236666 Ref: Cyclooxygenase-2 inhibitor NS398 enhances radiosensitivity of radioresistant esophageal cancer cells by inhibiting AKT activation and inducing apoptosis. PMID: 20486853 Ref: Expression of ki-67 antigen and caspase-3 protein in benign lesions and esophageal carcinoma. PMID: 20683021 Ref: [Apoptosis effects on human esophageal cancer cells by soyasaponin Bb and its machanism]. PMID: 20726234 Ref: [Mechanism of apoptosis of esophageal cancer EC9706 in nude mice induced by all-trans retinoic acid]. PMID: 21223795 |
Ref: A cyclooxygase-2 inhibitor NS-398-enhanced apoptosis of esophageal carcinoma cell EC9706 by adjusting expression of survivin and caspase-3. PMID: 21329005 Ref: Role of Smac in determining the chemotherapeutic response of esophageal squamous cell carcinoma. PMID: 21676925 Ref: Deciphering the role of paclitaxel in the SKGT4 human esophageal adenocarcinoma cell line. PMID: 21935570 Ref: [Inhibitory effects of Gecko alcohol extract on human esophageal squamous carcinoma cell line EC-109 proliferation and associated mechanism]. PMID: 22066391 Ref: [Apoptosis and growth arrest of human esophageal squamous cell carcinoma cell EC9706 induced by Fufangkushen injection]. PMID: 22322065 |
Ref: The novel indole compound SK228 induces apoptosis and FAK/Paxillin disruption in tumor cell lines and inhibits growth of tumor graft in the nude mouse. PMID: 22015944 Ref: Genetic variant in CASP3 affects promoter activity and risk of esophageal squamous cell carcinoma. PMID: 22136337 Ref: Suppression of esophageal cancer cell growth using curcumin, (-)-epigallocatechin-3-gallate and lovastatin. PMID: 22253518 Ref: Curcumin induces cell death in esophageal cancer cells through modulating Notch signaling. PMID: 22363450 Ref: Antitumor activity of folate-targeted, paclitaxel-loaded polymeric micelles on a human esophageal EC9706 cancer cell line. PMID: 22848173 Ref: Apoptosis induced by adenosine involves endoplasmic reticulum stress in EC109 cells. PMID: 22859272 Ref: Stellera chamaejasme L. extract induces apoptosis of human lung cancer cells via activation of the death receptor-dependent pathway. PMID: 23170112 |
Ref: Growth inhibitory effects and molecular mechanisms of crotoxin treatment in esophageal Eca-109 cells and transplanted tumors in nude mice. PMID: 23202800 Ref: Inhibition of farnesoid X receptor controls esophageal cancer cell growth in vitro and in nude mouse xenografts. PMID: 23280144 Ref: The variability of oxLDL-induced cytotoxicity on different types of cell lines. PMID: 23479334 Ref: Endoplasmic reticulum stress sensitizes human esophageal cancer cell to radiation. PMID: 23555162 Ref: Phaseoloideside E, a novel natural triterpenoid saponin identified from Entada phaseoloides, induces apoptosis in Ec-109 esophageal cancer cells through reactive oxygen species generation. PMID: 23782641 Ref: Small proline-rich repeat protein 3 enhances the sensitivity of esophageal cancer cells in response to DNA damage-induced apoptosis. PMID: 23820115 Ref: The radiation-sensitizing effect of flavopiridol in the esophageal cancer cell line Eca109. PMID: 23833659 |
Ref: Primary in vitro and in vivo evaluation of norcantharidin-chitosan/poly (vinyl alcohol) for cancer treatment. PMID: 24156408 Ref: The HSP90 inhibitor 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin-resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway. PMID: 24317439 Ref: Anti-tumor activity and relative mechanism of ethanolic extract of Marsdenia tenacissima (Asclepiadaceae) against human hematologic neoplasm in vitro and in vivo. PMID: 24583069 Ref: Overexpression of OLC1 promotes tumorigenesis of human esophageal squamous cell carcinoma. PMID: 24608342 Ref: Assessment of M867, a selective caspase-3 inhibitor, in an orthotopic mouse model for non-small cell lung carcinoma. PMID: 24660105 Ref: The molecular mechanisms of Tanshinone IIA on the apoptosis and arrest of human esophageal carcinoma cells. PMID: 24829906 Ref: Anti-tumor effects of flavonoids from the ethnic medicine Docynia delavayi (Franch.) Schneid. and its possible mechanism. PMID: 24940817 Ref: [Celecoxib antagonizes the cytotoxic effect of carboplatin in human esophageal cancer cells]. PMID: 24968832 Ref: Aberrant epigenetic alteration in Eca9706 cells modulated by nanoliposomal quercetin combined with butyrate mediated via epigenetic-NF-kappaB signaling. PMID: 24969881 Ref: [Effect of downregulation of Tiam1 by siRNA on esophageal squamous cell carcinoma EC9706 cells]. PMID: 24989909 Ref: DADS suppresses human esophageal xenograft tumors through RAF/MEK/ERK and mitochondria-dependent pathways. PMID: 25026173 Ref: Effects of PLCE1 gene silencing by RNA interference on cell cycling and apoptosis in esophageal carcinoma cells. PMID: 25041015 Ref: Anti-CSC effects in human esophageal squamous cell carcinomas and Eca109/9706 cells induced by nanoliposomal quercetin alone or combined with CD 133 antiserum. PMID: 25374189 Ref: Induction of apoptosis by eicosapentaenoic acid in esophageal squamous cell carcinoma. PMID: 25503142 Ref: Myricetin enhance chemosensitivity of 5-fluorouracil on esophageal carcinoma in vitro and in vivo. PMID: 25788859 |
Ref: BTEB2 prevents neuronal apoptosis via promoting bad phosphorylation in rat intracerebral hemorrhage model. PMID: 24770868 Ref: Combination of SNX-2112 with 5-FU exhibits antagonistic effect in esophageal cancer cells. PMID: 25333998 Ref: Anticancer effects of crocetin in human esophageal squamous cell carcinoma KYSE-150 cells. PMID: 25663893 Ref: Indomethacin induces apoptosis in the EC109 esophageal cancer cell line by releasing second mitochondria-derived activator of caspase and activating caspase-3. PMID: 25673090 Ref: Nimesulide inhibits the growth of human esophageal carcinoma cells by inactivating the JAK2/STAT3 pathway. PMID: 25724470 Ref: Artesunate induces apoptosis and inhibits growth of Eca109 and Ec9706 human esophageal cancer cell lines in vitro and in vivo. PMID: 25816175 Ref: The anti-esophageal cancer cell activity by a novel tyrosine/phosphoinositide kinase inhibitor PP121. PMID: 26235881 Ref: [Curcumin induces apoptosis by PTEN/PI3K/AKT pathway in EC109 cells]. PMID: 26248429 Ref: Hyperthermia induces apoptosis by targeting Survivin in esophageal cancer. PMID: 26352384 Ref: Ochratoxin A induces DNA damage and G2 phase arrest in human esophageal epithelium Het-1A cells in vitro. PMID: 26354382 Ref: Prognostic value of Caspase-3 expression in cancers of digestive tract: a meta-analysis and systematic review. PMID: 26379814 Ref: Molecular characterization of antitumor effects of the rhizome extract from Curcuma zedoaria on human esophageal carcinoma cells. PMID: 26498695 Ref: Compound Radix Sophorae Flavescentis exerts antitumor effects by inhibiting the proliferation and inducing the apoptosis of esophageal carcinoma TE-8 cells. PMID: 26622820 Ref: [The effects of curcumin on PTEN/PI3K/Akt pathway in Ec109 cells]. PMID: 26827544 |
Ref: Gambogic acid enhances the radiosensitivity of human esophageal cancer cells by inducing reactive oxygen species via targeting Akt/mTOR pathway. PMID: 26318432 Ref: Autophagy and Apoptosis Play Opposing Roles in Overall Survival of Esophageal Squamous Cell Carcinoma. PMID: 26980476 Ref: Costunolide Induces Apoptosis through Generation of ROS and Activation of P53 in Human Esophageal Cancer Eca-109 Cells. PMID: 27078502 Ref: Analysis of esophageal cancer cell lines exposed to X-ray based on radiosensitivity influence by tumor necrosis factor-alpha. PMID: 27127936 Ref: The antibacterial peptide from Bombyx mori cecropinXJ induced growth arrest and apoptosis in human hepatocellular carcinoma cells. PMID: 27347099 Ref: Psoralidin inhibits proliferation and enhances apoptosis of human esophageal carcinoma cells via NF-kappaB and PI3K/Akt signaling pathways. PMID: 27446379 Ref: Thioridazine Sensitizes Esophageal Carcinoma Cell Lines to Radiotherapy-Induced Apoptosis In Vitro and In Vivo. PMID: 27453171 Ref: beta-Carotene synergistically enhances the anti-tumor effect of 5-fluorouracil on esophageal squamous cell carcinoma in vivo and in vitro. PMID: 27586268 |
Ref: Effects and Mechanisms of Metformin on the Proliferation of Esophageal Cancer Cells In Vitro and In Vivo. PMID: 27857021 Ref: Telomerase antagonist imetelstat increases radiation sensitivity in esophageal squamous cell carcinoma. PMID: 28099140 Ref: Azoxystrobin Induces Apoptosis of Human Esophageal Squamous Cell Carcinoma KYSE-150 Cells through Triggering of the Mitochondrial Pathway. PMID: 28567017 Ref: Down-regulation of XIAP enhances the radiosensitivity of esophageal cancer cells in vivo and in vitro. PMID: 28821565 Ref: FGFR2 regulation by picrasidine Q inhibits the cell growth and induces apoptosis in esophageal squamous cell carcinoma. PMID: 28857247 Ref: RNAi-mediated TCF-3 gene silencing inhibits proliferation of Eca-109 esophageal cancer cells by inducing apoptosis. PMID: 28864779 Ref: Epigallocatechin-3-gallate suppresses cell proliferation and promotes apoptosis in Ec9706 and Eca109 esophageal carcinoma cells. PMID: 28943954 Ref: Epigallocatechin-3-gallate promotes apoptosis and reversal of multidrug resistance in esophageal cancer cells. PMID: 28964574 Ref: Expression and function of tetraspanin 1 in esophageal carcinoma. PMID: 29422958 |
Ref: miR-486 functions as a tumor suppressor in esophageal cancer by targeting CDK4/BCAS2. PMID: 29115564 Ref: HOXC13 promotes proliferation of esophageal squamous cell carcinoma via repressing transcription of CASP3. PMID: 29168599 Ref: Thymoquinone Augments Cisplatin-Induced Apoptosis on Esophageal Carcinoma Through Mitigating the Activation of JAK2/STAT3 Pathway. PMID: 29197940 Ref: Potent hydrazone derivatives targeting esophageal cancer cells. PMID: 29475156 Ref: Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma In Vitro and Patient-Derived Xenografts In Vivo. PMID: 29695636 Ref: Isoalantolactone induces apoptosis through reactive oxygen species-dependent upregulation of death receptor 5 in human esophageal cancer cells. PMID: 29800641 Ref: Liriodenine enhances radiosensitivity in esophageal cancer ECA-109 cells by inducing apoptosis and G2/M arrest. PMID: 30250568 |