Primary Site >> Pancreatic Cancer

Gene >> CASP1

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Ref: Suppression of intracellular resistance factors by adriamycin augments heat-induced apoptosis via interleukin-1beta-converting enzyme activation in pancreatic carcinoma cells.
PMID: 9590133
Ref: Interleukin 1beta-converting enzyme (caspase-1) is overexpressed in adenocarcinoma of the pancreas.
PMID: 9661876
 Ref: Inhibition of epidermal growth factor-induced interleukin-1beta-converting enzyme expression reduces proliferation in the pancreatic carcinoma cell line AsPC-1.
PMID: 10493505
 Ref: MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells.
PMID: 10972974
 Ref: Inhibition of caspase-1 induces cell death in pancreatic carcinoma cells and potentially modulates expression levels of bcl-2 family proteins.
PMID: 11226429
Ref: Overexpression of caspase-1 (interleukin-1beta converting enzyme) in chronic pancreatitis and its participation in apoptosis and proliferation.
PMID: 11345139
Ref: Interferon gamma inhibits growth of human pancreatic carcinoma cells via caspase-1 dependent induction of apoptosis.
PMID: 11454803
Ref: Overexpression of caspase-1 in pancreatic disorders: implications for a function besides apoptosis.
PMID: 11985974
 Ref: Overexpression of Caspase-1 in adenocarcinoma of pancreas and chronic pancreatitis.
PMID: 14669344
 Ref: Human pancreatic carcinoma cells secrete bioactive interleukin-18 after treatment with 5-fluorouracil: implications for anti-tumor immune response.
PMID: 15684607
 Ref: Characterization of BAG3 cleavage during apoptosis of pancreatic cancer cells.
PMID: 20232307
 Ref: Complementary induction of immunogenic cell death by oncolytic parvovirus H-1PV and gemcitabine in pancreatic cancer.
PMID: 24574398
 Ref: NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma.
PMID: 28442553
Ref: Lack of chemopreventive effects of P2X7R inhibitors against pancreatic cancer.
PMID: 29228654