Primary Site >> Colorectal Cancer
Gene >> CASP1
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Ref: Mechanisms underlying apoptosis induced by combination of 5-fluorouracil and interferon-gamma. PMID: 9388485 |
Ref: The p42 variant of ETS1 protein rescues defective Fas-induced apoptosis in colon carcinoma cells. PMID: 10097131 Ref: Modulation of interleukin-18 expression in human colon carcinoma: consequences for tumor immune surveillance. PMID: 10371355 Ref: Interleukin 1 and interleukin 1beta converting enzyme (caspase 1) expression in the human colonic epithelial barrier. Caspase 1 downregulation in colon cancer. PMID: 10403737 |
Ref: Dietary regulation and localization of apoptosis cascade proteins in the colonic crypt. PMID: 10679813 Ref: Altered mechanisms of apoptosis in colon cancer: Fas resistance and counterattack in the tumor-immune conflict. PMID: 10911913 Ref: Characterization of bile salt-induced apoptosis in colon cancer cell lines. PMID: 10945641 Ref: Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-gamma. PMID: 10986288 Ref: Interferon-gamma sensitizes colonic epithelial cell lines to physiological and therapeutic inducers of colonocyte apoptosis. PMID: 11056003 Ref: Apoptosis cascade proteins are regulated in vivo by high intracolonic butyrate concentration: correlation with colon cancer inhibition. PMID: 11132927 |
Ref: Ceramide involvement in homocamptothecin- and camptothecin-induced cytotoxicity and apoptosis in colon HT29 cells. PMID: 11894136 Ref: Different molecular events account for butyrate-induced apoptosis in two human colon cancer cell lines. PMID: 12097652 Ref: Influence of the nitric oxide donor glyceryl trinitrate on apoptotic pathways in human colon cancer cells. PMID: 12105852 |
Ref: Coordinate regulation of IFN consensus sequence-binding protein and caspase-1 in the sensitization of human colon carcinoma cells to Fas-mediated apoptosis by IFN-gamma. PMID: 12794166 |
Ref: Flavone inhibition of tumor growth via apoptosis in vitro and in vivo. PMID: 15289867 |
Ref: Flavone initiates a hierarchical activation of the caspase-cascade in colon cancer cells. PMID: 15909122 Ref: Caspase-1 is a direct target gene of ETS1 and plays a role in ETS1-induced apoptosis. PMID: 16103071 |
Ref: Gossypol reduction of tumor growth through ROS-dependent mitochondria pathway in human colorectal carcinoma cells. PMID: 17597109 |
Ref: Microarray-based prediction of tumor response to neoadjuvant radiochemotherapy of patients with locally advanced rectal cancer. PMID: 18166477 Ref: The CEACAM1-mediated apoptosis pathway is activated by CEA and triggers dual cleavage of CEACAM1. PMID: 18278069 Ref: Mutational analysis of caspase 1, 4, and 5 genes in common human cancers. PMID: 18430458 Ref: Kaiware Daikon (Raphanus sativus L.) extract: a naturally multipotent chemopreventive agent. PMID: 18665601 |
Ref: Comparison of caspase genes for the induction of apoptosis following gene delivery. PMID: 19067254 |
Ref: Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases. PMID: 20226691 Ref: IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation. PMID: 20855874 Ref: Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4. PMID: 21118981 |
Ref: A functional role for Nlrp6 in intestinal inflammation and tumorigenesis. PMID: 21543645 Ref: Inflammasome-mediated suppression of inflammation-induced colorectal cancer progression is mediated by direct regulation of epithelial cell proliferation. PMID: 21555913 Ref: Prognostic impact of DeltaTAp73 isoform levels and their target genes in colon cancer patients. PMID: 21807636 Ref: Inflammasomes and Intestinal Tumorigenesis. PMID: 22768019 |
Ref: Complex roles of caspases in the pathogenesis of inflammatory bowel disease. PMID: 23219999 Ref: Anti-cancer effect and apoptosis induction of cordycepin through DR3 pathway in the human colonic cancer cell HT-29. PMID: 23941773 |
Ref: Liver X receptor beta activation induces pyroptosis of human and murine colon cancer cells. PMID: 25124554 |
Ref: Altered expression of caspases-4 and -5 during inflammatory bowel disease and colorectal cancer: Diagnostic and therapeutic potential. PMID: 25943872 Ref: X-shaped DNA potentiates therapeutic efficacy in colitis-associated colon cancer through dual activation of TLR9 and inflammasomes. PMID: 25971982 Ref: Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt. PMID: 26107252 Ref: Cell Free DNA of Tumor Origin Induces a 'Metastatic' Expression Profile in HT-29 Cancer Cell Line. PMID: 26133168 Ref: Methylene Blue Inhibits Caspases by Oxidation of the Catalytic Cysteine. PMID: 26400108 Ref: Liver X receptor ligand cytotoxicity in colon cancer cells and not in normal colon epithelial cells depends on LXRbeta subcellular localization. PMID: 26450852 |
Ref: Dietary cholesterol promotes AOM-induced colorectal cancer through activating the NLRP3 inflammasome. PMID: 26921636 Ref: Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice. PMID: 27059389 |
Ref: Inflammasomes and Cancer. PMID: 28093447 Ref: AIM2 regulates viability and apoptosis in human colorectal cancer cells via the PI3K/Akt pathway. PMID: 28243117 Ref: Apremilast Induces Apoptosis of Human Colorectal Cancer Cells with Mutant KRAS. PMID: 28668883 |