Primary Site >> Colorectal Cancer

Gene >> CA12

  • 2005
  • 2007
  • 2012
  • 2015
  • 2016
  • 2017
Ref: Expression of von Hippel-Lindau tumor suppressor and tumor-associated carbonic anhydrases IX and XII in normal and neoplastic colorectal mucosa.
PMID: 15849821
Ref: Carbonic anhydrase IX is highly expressed in hereditary nonpolyposis colorectal cancer.
PMID: 17855694
Ref: Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy.
PMID: 22498007
Ref: Knock-down of hypoxia-induced carbonic anhydrases IX and XII radiosensitizes tumor cells by increasing intracellular acidosis.
PMID: 23316475
Ref: Carbonic anhydrase XII is a new therapeutic target to overcome chemoresistance in cancer cells.
PMID: 25686827
Ref: Serum miR-372 is a Diagnostic and Prognostic Biomarker in Patients with Early Colorectal Cancer.
PMID: 26179262
Ref: Development of certain new 2-substituted-quinazolin-4-yl-aminobenzenesulfonamide as potential antitumor agents.
PMID: 26774930
Ref: Genetic disruption of the pHi-regulating proteins Na+/H+ exchanger 1 (SLC9A1) and carbonic anhydrase 9 severely reduces growth of colon cancer cells.
PMID: 28055960