Primary Site >> Colorectal Cancer

Gene >> C1GALT1C1

  • 2008
  • 2014
  • 2015
  • 2018
Ref: Immunocytochemical analysis for intracellular dynamics of C1GalT associated with molecular chaperone, Cosmc.
PMID: 18061573
Ref: Human tumor antigens Tn and sialyl Tn arise from mutations in Cosmc.
PMID: 18339842
 Ref: The molecular chaperone Cosmc enhances malignant behaviors of colon cancer cells via activation of Akt and ERK.
PMID: 23390052
 Ref: Aberrant Cosmc genes result in Tn antigen expression in human colorectal carcinoma cell line HT-29.
PMID: 26045765
 Ref: Oncogenic BRAFV600E drives expression of MGL ligands in the colorectal cancer cell line HT29 through N-acetylgalactosamine-transferase 3.
PMID: 29894293
Ref: Aberrant O-glycosylation contributes to tumorigenesis in human colorectal cancer.
PMID: 29999571
Ref: Differential expression of Cosmc, T-synthase and mucins in Tn-positive colorectal cancers.
PMID: 30115016