Primary Site >> Colorectal Cancer

Gene >> BTK

  • 2000
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  • 2017
  • 2018
Ref: Analysis of the genetic alterations in a case of juvenile multiple colon carcinoma with hypogammaglobulinemia.
PMID: 11034248
Ref: Hypogammaglobulinaemia: cumulative experience in 49 patients in a tertiary care institution.
PMID: 12164371
Ref: Multiple colorectal neoplasms in X-linked agammaglobulinemia.
PMID: 17967562
Ref: Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling.
PMID: 19471023
Ref: Therapeutic antitumor immunity by checkpoint blockade is enhanced by ibrutinib, an inhibitor of both BTK and ITK.
PMID: 25730880
Ref: A novel oncogenic BTK isoform is overexpressed in colon cancers and required for RAS-mediated transformation.
PMID: 26804170
Ref: The Btk-dependent PIP5K1gamma lipid kinase activation by Fas counteracts FasL-induced cell death.
PMID: 28879546
Ref: Simultaneous use of erythropoietin and LFM-A13 as a new therapeutic approach for colorectal cancer.
PMID: 29160911
Ref: Erythropoietin Intensifies the Proapoptotic Activity of LFM-A13 in Cells and in a Mouse Model of Colorectal Cancer.
PMID: 29690619