Primary Site >> Colorectal Cancer
Gene >> BRIP1
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Ref: An MLH1 mutation links BACH1/FANCJ to colon cancer, signaling, and insight toward directed therapy. PMID: 20978114 |
Ref: FANCJ expression predicts the response to 5-fluorouracil-based chemotherapy in MLH1-proficient colorectal cancer. PMID: 22526901 |
Ref: Decreased FANCJ caused by 5FU contributes to the increased sensitivity to oxaliplatin in gastric cancer cells. PMID: 22968820 |
Ref: Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. PMID: 26681312 Ref: The Fanconi anemia DNA damage repair pathway in the spotlight for germline predisposition to colorectal cancer. PMID: 27165003 |
Ref: Molecular Portrait of Metastasis-Competent Circulating Tumor Cells in Colon Cancer Reveals the Crucial Role of Genes Regulating Energy Metabolism and DNA Repair. PMID: 28007957 |
Ref: Novel genetic mutations detected by multigene panel are associated with hereditary colorectal cancer predisposition. PMID: 30256826 Ref: Rare loss of function variants in candidate genes and risk of colorectal cancer. PMID: 30267214 |