Primary Site >> Liver Cancer
Gene >> BRD4
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Ref: BRD4 promotes tumor growth and epithelial-mesenchymal transition in hepatocellular carcinoma. PMID: 25816404 Ref: BRD4 induces cell migration and invasion in HCC cells through MMP-2 and MMP-9 activation mediated by the Sonic hedgehog signaling pathway. PMID: 26622824 Ref: BRD4 is a novel therapeutic target for liver fibrosis. PMID: 26644586 |
Ref: Downregulation of miR-329 promotes cell invasion by regulating BRD4 and predicts poor prognosis in hepatocellular carcinoma. PMID: 26456956 Ref: Epigenetic reader BRD4 inhibition as a therapeutic strategy to suppress E2F2-cell cycle regulation circuit in liver cancer. PMID: 27081696 Ref: Single Agent and Synergistic Activity of the "First-in-Class" Dual PI3K/BRD4 Inhibitor SF1126 with Sorafenib in Hepatocellular Carcinoma. PMID: 27496136 |
Ref: Transcriptional Elongation Control of Hepatitis B Virus Covalently Closed Circular DNA Transcription by Super Elongation Complex and BRD4. PMID: 28694331 |
Ref: Hepatocyte Wnts Are Dispensable During Diethylnitrosamine and Carbon Tetrachloride-Induced Injury and Hepatocellular Cancer. PMID: 29519268 Ref: microRNA-608 inhibits human hepatocellular carcinoma cell proliferation via targeting the BET family protein BRD4. PMID: 29777702 Ref: PES1 is transcriptionally regulated by BRD4 and promotes cell proliferation and glycolysis in hepatocellular carcinoma. PMID: 30172011 |