Primary Site >> Stomach Cancer
Gene >> BRCA2
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Ref: Confirmation of susceptibility locus on chromosome 13 in Australian breast cancer families. PMID: 8682513 |
Ref: Mutations at coding mononucleotide repeats in gastric cancer with the microsatellite mutator phenotype. PMID: 9652743 |
Ref: Cancer risks in BRCA2 mutation carriers. PMID: 10433620 Ref: A novel sensitive method to detect frameshift mutations in exonic repeat sequences of cancer-related genes. PMID: 10545425 Ref: Incidence of malignant tumours in relatives of BRCA1 and BRCA2 germline mutation carriers. PMID: 10615237 |
Ref: The effect of mismatch repair deficiency on tumourigenesis; microsatellite instability affecting genes containing short repeated sequences. PMID: 10601558 |
Ref: Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer. PMID: 11179017 Ref: The rate of the 6174delT founder Jewish mutation in BRCA2 in patients with non-colonic gastrointestinal tract tumours in Israel. PMID: 11207041 Ref: MRNA expression of genes altered by 5-azacytidine treatment in cancer cell lines is associated with clinicopathological parameters of human cancers. PMID: 11768609 |
Ref: Mutation analysis of the CHK2 gene in breast carcinoma and other cancers. PMID: 12052256 Ref: Preferential loss of Fhit expression in signet-ring cell and Krukenberg subtypes of gastric cancer. PMID: 12218081 Ref: BRCA2 gene mutations in families with aggregations of breast and stomach cancers. PMID: 12373604 Ref: Polymorphisms in DNA repair genes and associations with cancer risk. PMID: 12496039 |
Ref: A high frequency of BRCA2 gene mutations in Polish families with ovarian and stomach cancer. PMID: 14647210 |
Ref: Cancer risks for male carriers of germline mutations in BRCA1 or BRCA2: a review of the literature. PMID: 14966099 Ref: Cancer variation associated with the position of the mutation in the BRCA2 gene. PMID: 15131399 Ref: Risk of cancer at sites other than the breast in Swedish families eligible for BRCA1 or BRCA2 mutation testing. PMID: 15550590 |
Ref: CGMIM: automated text-mining of Online Mendelian Inheritance in Man (OMIM) to identify genetically-associated cancers and candidate genes. PMID: 15796777 Ref: BRCA2 germline mutation in a woman with uterine serous papillary carcinoma--case report. PMID: 16051327 |
Ref: Spontaneous and irradiation-induced tumor susceptibility in BRCA2 germline mutant mice and cooperative effects with a p53 germline mutation. PMID: 16546942 |
Ref: Germline E-cadherin mutations in familial lobular breast cancer. PMID: 17660459 |
Ref: Characterization of the pathogenic mechanism of a novel BRCA2 variant in a Chinese family. PMID: 17657584 Ref: The prevalence of BRCA1 and BRCA2 germline mutations in high-risk breast cancer patients of Chinese Han nationality: two recurrent mutations were identified. PMID: 17851763 Ref: Gastric cancer with high-level microsatellite instability: target gene mutations, clinicopathologic features, and long-term survival. PMID: 18440592 |
Ref: Cancer prevalence in 129 breast-ovarian cancer families tested for BRCA1 and BRCA2 mutations. PMID: 20459916 |
Ref: Germline mutations of the E-cadherin gene in families with inherited invasive lobular breast carcinoma but no diffuse gastric cancer. PMID: 21271559 Ref: Effects of acute and chronic hypoxia on the radiosensitivity of gastric and esophageal cancer cells. PMID: 21965748 |
Ref: BRCA1 and BRCA2 mutations among familial breast cancer patients from Costa Rica. PMID: 21895635 Ref: BRCA1 and BRCA2 mutations among ovarian cancer patients from Colombia. PMID: 22044689 Ref: Genetic testing by cancer site: stomach. PMID: 22846738 Ref: [Genetic counselling in male carriers of BRCA1 and BRCA2 gene mutations]. PMID: 22920210 Ref: [Prophylactic surgery in common hereditary cancer syndromes]. PMID: 23815011 |
Ref: BRCA2 affects the efficiency of DNA double-strand break repair in response to N-nitroso compounds with differing carcinogenic potentials. PMID: 23833673 |
Ref: Clinical and molecular characterization of the BRCA2 p.Asn3124Ile variant reveals substantial evidence for pathogenic significance. PMID: 24728577 Ref: Low ATM protein expression and depletion of p53 correlates with olaparib sensitivity in gastric cancer cell lines. PMID: 24841718 |
Ref: A case of familial breast cancer with double heterozygosity for BRCA1 and BRCA2 genes. PMID: 23242612 Ref: Possible association of the BRCA2 gene C5972T variant with gastric cancer: a study on Polish population. PMID: 25533971 Ref: Lobular breast cancer: incidence and genetic and non-genetic risk factors. PMID: 25848941 Ref: Hereditary Diffuse Gastric Cancer Syndrome: CDH1 Mutations and Beyond. PMID: 26182300 Ref: The role of BRCA1 and BRCA2 mutations in prostate, pancreatic and stomach cancers. PMID: 26236408 Ref: Gene mutations in gastric cancer: a review of recent next-generation sequencing studies. PMID: 26364057 Ref: A mutational signature in gastric cancer suggests therapeutic strategies. PMID: 26511885 |
Ref: BRCA1 founder mutations do not contribute to increased risk of gastric cancer in the Polish population. PMID: 26779294 Ref: Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer. PMID: 26857264 Ref: Comprehensive mutation profiling of mucinous gastric carcinoma. PMID: 27313181 |
Ref: Familial Gastrointestinal Stromal Tumor with Germline KIT Mutations Accompanying Hereditary Breast and Ovarian Cancer Syndrome. PMID: 28314314 Ref: Hereditary diffuse gastric cancer and lynch syndromes in a BRCA1/2 negative breast cancer patient. PMID: 28702897 Ref: Genomic alterations in advanced gastric cancer endoscopic biopsy samples using targeted next-generation sequencing. PMID: 28744403 Ref: Co-targeting c-Met and DNA double-strand breaks (DSBs): Therapeutic strategies in BRCA-mutated gastric carcinomas. PMID: 28890386 Ref: Genetic Gastric Cancer Susceptibility in the International Clinical Cancer Genomics Community Research Network. PMID: 29025585 Ref: Actionable gene-based classification toward precision medicine in gastric cancer. PMID: 29089060 Ref: A case of gastric cancer metastasis to the breast in a female with BRCA2 germline mutation and literature review. PMID: 29202657 |
Ref: BRCA1 and BRCA2 expression patterns and prognostic significance in digestive system cancers. PMID: 29126833 Ref: Prognostic Value of the Expression of DNA Repair-Related Biomarkers Mediated by Alcohol in Gastric Cancer Patients. PMID: 29331492 Ref: Men seeking counselling in a Breast Cancer Risk Evaluation Clinic. PMID: 29456621 Ref: Somatic mutational profiles of stage II and III gastric cancer according to tumor microenvironment immune type. PMID: 30239046 |