Primary Site >> Stomach Cancer
Gene >> BRCA1
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Ref: Allelic imbalance in gastric cancer: an affected site on chromosome arm 3p. PMID: 7547634 Ref: Genetic polymorphisms and susceptibility to cancer development. PMID: 7581488 |
Ref: Confirmation of susceptibility locus on chromosome 13 in Australian breast cancer families. PMID: 8682513 |
Ref: Frequent microsatellite instability and loss of heterozygosity in the region including BRCA1 (17q21) in young patients with gastric cancer. PMID: 9592181 Ref: Nonsense mutation at codon 63 of the BRCA1 gene in Japanese breast cancer patients. PMID: 9765620 |
Ref: A novel sensitive method to detect frameshift mutations in exonic repeat sequences of cancer-related genes. PMID: 10545425 Ref: Incidence of malignant tumours in relatives of BRCA1 and BRCA2 germline mutation carriers. PMID: 10615237 |
Ref: Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer. PMID: 11179017 Ref: Primary ovarian carcinomas display multiple methylator phenotypes involving known tumor suppressor genes. PMID: 11238060 Ref: Somatic mutations in the DNA damage-response genes ATR and CHK1 in sporadic stomach tumors with microsatellite instability. PMID: 11691784 |
Ref: Preferential loss of Fhit expression in signet-ring cell and Krukenberg subtypes of gastric cancer. PMID: 12218081 |
Ref: Cancer risks for male carriers of germline mutations in BRCA1 or BRCA2: a review of the literature. PMID: 14966099 Ref: Risk of cancer at sites other than the breast in Swedish families eligible for BRCA1 or BRCA2 mutation testing. PMID: 15550590 |
Ref: [Genetic instability on chromosome 17q21 in gastric cancer of Chinese patients]. PMID: 16011248 |
Ref: Genetic instability of BRCA1 gene at locus D17S855 is related to clinicopathological behaviors of gastric cancer from Chinese population. PMID: 16830385 |
Ref: [Hierarchical clustering analysis to detect associations between clinical and pathological features of gastric tumors and hypermethylation of suppressor genes]. PMID: 17369979 Ref: Germline E-cadherin mutations in familial lobular breast cancer. PMID: 17660459 Ref: Novel NBS1 heterozygous germ line mutation causing MRE11-binding domain loss predisposes to common types of cancer. PMID: 18056440 |
Ref: Roles and responsibilities of a medical geneticist. PMID: 17624600 Ref: Characterization of the pathogenic mechanism of a novel BRCA2 variant in a Chinese family. PMID: 17657584 Ref: The prevalence of BRCA1 and BRCA2 germline mutations in high-risk breast cancer patients of Chinese Han nationality: two recurrent mutations were identified. PMID: 17851763 Ref: ERCC1 and BRCA1 mRNA expression levels in metastatic malignant effusions is associated with chemosensitivity to cisplatin and/or docetaxel. PMID: 18402708 Ref: Promoter methylation of cancer-related genes in gastric carcinoma. PMID: 18566573 Ref: Reprimo as a potential biomarker for early detection in gastric cancer. PMID: 18829507 Ref: DNA methylation profile in diffuse type gastric cancer: evidence for hypermethylation of the BRCA1 promoter region in early-onset gastric carcinogenesis. PMID: 19399343 |
Ref: Frequent loss of heterozygosity at the interferon regulatory factor-1 gene locus in breast cancer. PMID: 19697121 Ref: Expression of TRF1, TRF2, TIN2, TERT, KU70, and BRCA1 proteins is associated with telomere shortening and may contribute to multistage carcinogenesis of gastric cancer. PMID: 20127252 Ref: BRCA1 and XRCC1 polymorphisms associated with survival in advanced gastric cancer treated with taxane and cisplatin. PMID: 20331623 Ref: Cancer prevalence in 129 breast-ovarian cancer families tested for BRCA1 and BRCA2 mutations. PMID: 20459916 Ref: Epstein-Barr virus-specific methylation of human genes in gastric cancer cells. PMID: 21194482 |
Ref: Trastuzumab and beyond: sequencing cancer genomes and predicting molecular networks. PMID: 20975737 Ref: Germline mutations of the E-cadherin gene in families with inherited invasive lobular breast carcinoma but no diffuse gastric cancer. PMID: 21271559 Ref: mRNA expression of BRCA1, PIAS1, and PIAS4 and survival after second-line docetaxel in advanced gastric cancer. PMID: 21862729 Ref: Effects of acute and chronic hypoxia on the radiosensitivity of gastric and esophageal cancer cells. PMID: 21965748 |
Ref: BRCA1 and BRCA2 mutations among familial breast cancer patients from Costa Rica. PMID: 21895635 Ref: BRCA1 and BRCA2 mutations among ovarian cancer patients from Colombia. PMID: 22044689 Ref: Enhancement of anticancer efficacy of chemotherapeutics by gambogic acid against gastric cancer cells. PMID: 22444164 Ref: Genetic testing by cancer site: stomach. PMID: 22846738 Ref: [Genetic counselling in male carriers of BRCA1 and BRCA2 gene mutations]. PMID: 22920210 Ref: [Prophylactic surgery in common hereditary cancer syndromes]. PMID: 23815011 |
Ref: Decreased FANCJ caused by 5FU contributes to the increased sensitivity to oxaliplatin in gastric cancer cells. PMID: 22968820 Ref: Prognostic significance of BRCA1 expression in gastric cancer. PMID: 23292835 Ref: Genetic variants in DNA repair pathway genes and risk of esophageal squamous cell carcinoma and gastric adenocarcinoma in a Chinese population. PMID: 23504502 Ref: A three-gene signature as potential predictive biomarker for irinotecan sensitivity in gastric cancer. PMID: 23517622 Ref: Evidence for predictive role of BRCA1 and bTUBIII in gastric cancer. PMID: 23532817 Ref: Loss of BRCA1 expression leads to worse survival in patients with gastric carcinoma. PMID: 23569343 Ref: Differing effects of adjuvant chemotherapy according to BRCA1 nuclear expression in gastric cancer. PMID: 23633032 Ref: [Epigenetics in the pathogenesis and early detection of gastric cancer]. PMID: 24728435 |
Ref: [Synergistic interaction between melittin and chemotherapeutic agents and their possible mechanisms: an experimental research]. PMID: 24672950 Ref: Clinical and molecular characterization of the BRCA2 p.Asn3124Ile variant reveals substantial evidence for pathogenic significance. PMID: 24728577 Ref: Differential effect of MMSET mRNA levels on survival to first-line FOLFOX and second-line docetaxel in gastric cancer. PMID: 24809779 Ref: Low ATM protein expression and depletion of p53 correlates with olaparib sensitivity in gastric cancer cell lines. PMID: 24841718 Ref: Altered expression of hypoxia-inducible factor-1alpha (HIF-1alpha) and its regulatory genes in gastric cancer tissues. PMID: 24927122 Ref: [Promoter region methylation of DNA damage repair genes in human gastric cancer]. PMID: 25331470 Ref: Plasma mRNA expression levels of BRCA1 and TS as potential predictive biomarkers for chemotherapy in gastric cancer. PMID: 25496700 |
Ref: A case of familial breast cancer with double heterozygosity for BRCA1 and BRCA2 genes. PMID: 23242612 Ref: The functional BRCA1 rs799917 genetic polymorphism is associated with gastric cancer risk in a Chinese Han population. PMID: 25266802 Ref: Lobular breast cancer: incidence and genetic and non-genetic risk factors. PMID: 25848941 Ref: UHRF1 promotes proliferation of gastric cancer via mediating tumor suppressor gene hypermethylation. PMID: 26147747 Ref: The role of BRCA1 and BRCA2 mutations in prostate, pancreatic and stomach cancers. PMID: 26236408 Ref: Delineation of gastric cancer subtypes by co-regulated expression of receptor tyrosine kinases and chemosensitivity genes. PMID: 26396673 Ref: A mutational signature in gastric cancer suggests therapeutic strategies. PMID: 26511885 Ref: Patterns and functional implications of rare germline variants across 12 cancer types. PMID: 26689913 Ref: High Expression of IncRNA-PCNA-AS1 in Human Gastric Cancer and its Clinical Significances. PMID: 26731993 |
Ref: Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. PMID: 26681312 Ref: CDH1 germline mutations and hereditary lobular breast cancer. PMID: 26759166 Ref: BRCA1 founder mutations do not contribute to increased risk of gastric cancer in the Polish population. PMID: 26779294 Ref: Tissue microRNAs as predictive markers for gastric cancer patients undergoing palliative chemotherapy. PMID: 27081844 Ref: Predictive value of BRCA1 expression on the efficacy of chemotherapy based on anti-microtubule agents: a pooled analysis across different malignancies and agents. PMID: 27127763 Ref: Comprehensive mutation profiling of mucinous gastric carcinoma. PMID: 27313181 Ref: Successful personalized chemotherapy for metastatic gastric cancer based on quantitative BRCA1 mRNA expression level: A case report. PMID: 27313763 Ref: Screening Driving Transcription Factors in the Processing of Gastric Cancer. PMID: 27403158 Ref: Tumor profiling of co-regulated receptor tyrosine kinase and chemoresistant genes reveal different targeting options for lung and gastroesophageal cancers. PMID: 28078044 |
Ref: Germline Mutations in PALB2, BRCA1, and RAD51C, Which Regulate DNA Recombination Repair, in Patients With Gastric Cancer. PMID: 28024868 Ref: Clinical significance of UGT1A1 polymorphism and expression of ERCC1, BRCA1, TYMS, RRM1, TUBB3, STMN1 and TOP2A in gastric cancer. PMID: 28056823 Ref: Plasma mRNA as liquid biopsy predicts chemo-sensitivity in advanced gastric cancer patients. PMID: 28261345 Ref: Hereditary diffuse gastric cancer and lynch syndromes in a BRCA1/2 negative breast cancer patient. PMID: 28702897 Ref: Co-targeting c-Met and DNA double-strand breaks (DSBs): Therapeutic strategies in BRCA-mutated gastric carcinomas. PMID: 28890386 Ref: Genetic Gastric Cancer Susceptibility in the International Clinical Cancer Genomics Community Research Network. PMID: 29025585 Ref: A case of gastric cancer metastasis to the breast in a female with BRCA2 germline mutation and literature review. PMID: 29202657 Ref: Homologous Recombination Deficiency and Platinum-Based Therapy Outcomes in Advanced Breast Cancer. PMID: 29246904 |
Ref: CDH1 mutation screen in a BRCA1/2-negative familial breast-/ovarian cancer cohort. PMID: 28993866 Ref: Prognostic Value of the Expression of DNA Repair-Related Biomarkers Mediated by Alcohol in Gastric Cancer Patients. PMID: 29331492 Ref: Men seeking counselling in a Breast Cancer Risk Evaluation Clinic. PMID: 29456621 Ref: The association between BRCA1 gene polymorphism and cancer risk: a meta-analysis. PMID: 29492227 Ref: Association of MUC16 Mutation With Tumor Mutation Load and Outcomes in Patients With Gastric Cancer. PMID: 30098163 |