Primary Site >> Colorectal Cancer
Gene >> BRCA1
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Ref: Localization of a second NM23 gene, NME2, to chromosome 17q21-q22. PMID: 8406509 |
Ref: Risks of cancer in BRCA1-mutation carriers. Breast Cancer Linkage Consortium. PMID: 7907678 Ref: The inherited component of cancer. PMID: 7987639 Ref: [Genetic predisposition to cancer: familial forms of medullary thyroid cancer and breast cancer]. PMID: 8038990 Ref: Loss of heterozygosity studies in tumors from families with breast-ovarian cancer syndrome. PMID: 8076936 |
Ref: The genetics of breast and ovarian cancer. PMID: 7547224 Ref: Colorectal carcinomas show frequent allelic loss on the long arm of chromosome 17 with evidence for a specific target region. PMID: 7734302 Ref: Genetic developments in breast cancer. PMID: 10161380 |
Ref: Genetic counselling and testing for susceptibility to breast, ovarian and colon cancer: where are we today? PMID: 8548703 Ref: [Familial cancer and oncogenic factors]. PMID: 8678487 Ref: Prophylactic Oophorectomy: Reducing the U.S. Death Rate from Epithelial Ovarian Cancer. A Continuing Debate. PMID: 10388011 |
Ref: The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews. PMID: 9145676 Ref: The I1307K APC mutation does not predispose to colorectal cancer in Jewish Ashkenazi breast and breast-ovarian cancer kindreds. PMID: 9407954 Ref: Cancer genetics in the new era of molecular biology. PMID: 9616736 |
Ref: A novel BRCA1 mutation in an identical twin pair with similar clinical histories. PMID: 9406579 Ref: A microsatellite within the MUC1 locus at 1q21 is altered in the neoplastic cells of breast cancer patients. PMID: 9406583 Ref: Inherited susceptibility to breast and ovarian cancer. PMID: 9484622 Ref: Missense mutations in disease genes: a Bayesian approach to evaluate causality. PMID: 9585599 Ref: Loss of heterozygosity in the region including the BRCA1 gene on 17q in colon cancer. PMID: 9666805 Ref: The genetics of hereditary common cancers. PMID: 9690990 Ref: Genetic pathways of colorectal carcinogenesis rarely involve the PTEN and LKB1 genes outside the inherited hamartoma syndromes. PMID: 9708796 Ref: Hormonal etiology of epithelial ovarian cancer, with a hypothesis concerning the role of androgens and progesterone. PMID: 9839517 Ref: Hereditary Factors in Gynecologic Cancer. PMID: 10388122 Ref: BRCA1 in special populations. PMID: 15687550 |
Ref: Causes and consequences of microsatellite instability in endometrial carcinoma. PMID: 9927063 Ref: [Hereditary neoplastic diseases (genetic predisposition and cancer syndromes)]. PMID: 10204401 Ref: Mutations of a novel human RAD54 homologue, RAD54B, in primary cancer. PMID: 10362364 Ref: Colorectal cancer in hereditary breast cancer kindreds. PMID: 10458128 Ref: A novel sensitive method to detect frameshift mutations in exonic repeat sequences of cancer-related genes. PMID: 10545425 |
Ref: Tumour-specific distribution of BRCA1 promoter region methylation supports a pathogenetic role in breast and ovarian cancer. PMID: 10657950 Ref: Germline BRCA1 and HMLH1 mutations in a family with male and female breast carcinoma. PMID: 10709098 Ref: Incidence of BRCA1 and BRCA2 mutations in Ashkenazi colorectal cancer patients: preliminary study. PMID: 10769725 Ref: Identification of Rad51 alteration in patients with bilateral breast cancer. PMID: 10807537 Ref: Missense alterations of BRCA1 gene detected in diverse cancer patients. PMID: 10810408 Ref: BRCA1 and BRCA2 gene mutations: decision-making dilemmas concerning testing and management. PMID: 10841315 Ref: Health, life and disability insurance and hereditary risk for breast or colorectal cancer. PMID: 10859009 Ref: BRCA1 germline mutations in women with uterine serous papillary carcinoma. PMID: 10862837 Ref: Genetic analysis of a breast-ovarian cancer family, with 7 cases of colorectal cancer linked to BRCA1, fails to support a role for BRCA1 in colorectal tumorigenesis. PMID: 11072248 Ref: Differential effects of theaflavin monogallates on cell growth, apoptosis, and Cox-2 gene expression in cancerous versus normal cells. PMID: 11103814 |
Ref: Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer. PMID: 11179017 Ref: The frequency of the predominant Jewish mutations in BRCA1 and BRCA2 in unselected Ashkenazi colorectal cancer patients. PMID: 11207040 Ref: Localization of human BRCA1 and BRCA2 in non-inherited colorectal carcinomas and matched normal mucosas. PMID: 11497291 Ref: Adenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1. PMID: 11498787 Ref: Risk of breast and ovarian cancer in women with strong family histories. PMID: 11499690 Ref: Cancer risks in women with 2 breast or ovarian cancers: clues to genetic cancer susceptibility. PMID: 11745474 Ref: DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis. PMID: 11751682 |
Ref: The androgen receptor CAG repeat: a modifier of carcinogenesis? PMID: 12161010 Ref: BRCA1-related malignancies in a family presenting with von Recklinghausen's disease. PMID: 12217765 Ref: Cancer risk estimates for BRCA1 mutation carriers identified in a risk evaluation program. PMID: 12237282 Ref: Screening for microsatellite instability target genes in colorectal cancers. PMID: 12414815 Ref: Hereditary risk of women's cancers. PMID: 12475549 Ref: [Recommendations for the management of women with an increased genetic risk of gynaecological cancer]. PMID: 12518519 Ref: [Report on the first year of the activity of the National Oncological RD Consortium]. PMID: 12563351 |
Ref: A high-throughput nonisotopic protein truncation test. PMID: 12524552 Ref: Identification of differentially expressed genes associated with colorectal cancer liver metastasis. PMID: 12802093 Ref: Intratumoral heterogeneity in microsatellite alterations in BRCA1 and PTEN regions in sporadic colorectal cancer. PMID: 14527905 Ref: Does the occurrence of certain rare cancers indicate an inherited cancer susceptibility? PMID: 14574163 Ref: Prognostic significance of the allelic loss of the BRCA1 gene in colorectal cancer. PMID: 14633957 Ref: Functional and physical interactions between BRCA1 and p53 in transcriptional regulation of the IGF-IR gene. PMID: 14710355 |
Ref: BRCA1 and BRCA2 founder mutations and the risk of colorectal cancer. PMID: 14709734 Ref: Frequency of BRCA1 and BRCA2 mutations in unselected Ashkenazi Jewish patients with colorectal cancer. PMID: 14709740 Ref: BRCA germline mutations in Jewish women with uterine serous papillary carcinoma. PMID: 14766242 Ref: The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe. PMID: 15048074 Ref: [Report of the National Oncology Research and Developement Consortium, 2003]. PMID: 15105900 Ref: Possible causes of chromosome instability: comparison of chromosomal abnormalities in cancer cell lines with mutations in BRCA1, BRCA2, CHK2 and BUB1. PMID: 15162061 Ref: No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer. PMID: 15217503 Ref: Unravelling the genetics of prostate cancer. PMID: 15264274 Ref: Re: BRCA1 and BRCA2 founder mutations and the risk of colorectal cancer. PMID: 15292392 Ref: Microelectronic DNA assay for the detection of BRCA1 gene mutations. PMID: 15307445 Ref: Bias in intervention studies that enroll patients from high-risk clinics. PMID: 15316055 Ref: Evaluation of psychosocial effects of pre-symptomatic testing for breast/ovarian and colon cancer pre-disposing genes: a 12-month follow-up. PMID: 15340261 Ref: Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. PMID: 15526363 Ref: [Genetic predisposition and ovarian cancer]. PMID: 15630879 Ref: Inheritance of cancer. PMID: 20704938 |
Ref: [DNA-analysis in hereditary cancer: the importance of a reliable family history]. PMID: 15688834 Ref: Coinheritance of BRCA1 and BRCA2 mutations with Fanconi anemia and Bloom syndrome mutations in Ashkenazi Jewish population: possible role in risk modification for cancer development. PMID: 15726604 Ref: Hereditary breast/ovarian and colorectal cancer genetics knowledge in a national sample of US physicians. PMID: 15784723 Ref: No MSH6 germline mutations in breast cancer families with colorectal and/or endometrial cancer. PMID: 15805151 Ref: Analysis of microsatellite instability and BRCA1 mutations in patients from hereditary nonpolyposis colorectal cancer (HNPCC) family. PMID: 15921010 Ref: Psychological impact of genetic testing for cancer susceptibility: an update of the literature. PMID: 15937976 Ref: Psychological distress in women at risk of hereditary breast/ovarian or HNPCC cancers in the absence of demonstrated mutations. PMID: 15951962 Ref: Hereditary breast cancer syndromes in a Turkish population. Results of molecular germline analysis. PMID: 15993273 Ref: [Genetic instability on chromosome 17q21 in gastric cancer of Chinese patients]. PMID: 16011248 Ref: Effect of NS398 on metastasis-associated gene expression in a human colon cancer cell line. PMID: 16038031 Ref: Quantitative analysis of BRCA1, BRCA2 and Hmsh2 mRNA expression in colorectal Lieberkuhnien adenocarcinomas and matched normal mucosa: relationship with cellular proliferation. PMID: 16158938 Ref: [Hereditary predispositions to gynaecological cancers]. PMID: 16256400 Ref: Organization and running of the first comprehensive hereditary cancer clinic in India. PMID: 20223043 |
Ref: CtIP, a candidate tumor susceptibility gene is a team player with luminaries. PMID: 16249056 Ref: Multiplexed profiling of candidate genes for CpG island methylation status using a flexible PCR/LDR/Universal Array assay. PMID: 16369045 Ref: Expression of DNA double-strand break repair proteins ATM and BRCA1 predicts survival in colorectal cancer. PMID: 16533773 Ref: RNASEL mutation screening and association study in Ashkenazi and non-Ashkenazi prostate cancer patients. PMID: 16537704 Ref: [Hereditary ovarian cancer]. PMID: 16768054 Ref: Nordic collaborative study of the BARD1 Cys557Ser allele in 3956 patients with cancer: enrichment in familial BRCA1/BRCA2 mutation-negative breast cancer but not in other malignancies. PMID: 16825437 Ref: Development of a Premature Stop Codon-detection method based on a bacterial two-hybrid system. PMID: 16948859 Ref: Inherited association of breast and colorectal cancer: limited role of CHEK2 compared with high-penetrance genes. PMID: 17026620 Ref: A multicenter study of cancer incidence in CHEK2 1100delC mutation carriers. PMID: 17164383 |
Ref: Cancer risks in carriers of the BRCA1/2 Ashkenazi founder mutations. PMID: 17307836 Ref: BRCA1a has antitumor activity in TN breast, ovarian and prostate cancers. PMID: 17384678 Ref: Morphological features of TMPRSS2-ERG gene fusion prostate cancer. PMID: 17385188 Ref: A diagnostic dilemma following risk-reducing surgery for BRCA1 mutation - a case report of primary papillary serous carcinoma presenting as sigmoid cancer. PMID: 17850658 Ref: Society of Gynecologic Oncologists Education Committee statement on risk assessment for inherited gynecologic cancer predispositions. PMID: 17950381 Ref: Novel NBS1 heterozygous germ line mutation causing MRE11-binding domain loss predisposes to common types of cancer. PMID: 18056440 |
Ref: Higher occurrence of childhood cancer in families with germline mutations in BRCA2, MMR and CDKN2A genes. PMID: 18481196 Ref: Inherited cancer predisposition syndromes in Greece. PMID: 18505076 Ref: APC shuttling to the membrane, nucleus and beyond. PMID: 18848448 Ref: Impact of oxaliplatin and a novel DACH-platinum complex in the gene expression of HCT116 colon cancer cells. PMID: 18949432 |
Ref: Allelotyping, microsatellite instability, and BRAF mutation analyses in common and atypical melanocytic nevi and primary cutaneous melanomas. PMID: 19461239 Ref: Germline variants of the promyelocytic leukemia tumor suppressor gene in patients with familial cancer. PMID: 19728758 Ref: Nucleation capacity and presence of centrioles define a distinct category of centrosome abnormalities that induces multipolar mitoses in cancer cells. PMID: 19768832 Ref: Cancer risk assessment by rural and Appalachian family medicine physicians. PMID: 19780917 Ref: Aneuploidy is associated with TP53 expression but not with BRCA1 or TERT expression in sporadic colorectal cancer. PMID: 20032382 |
Ref: Survival in women with MMR mutations and ovarian cancer: a multicentre study in Lynch syndrome kindreds. PMID: 19635727 Ref: The contribution of founder mutations in BRCA1 to breast and ovarian cancer in Lithuania. PMID: 20345474 Ref: Common genetic variants and cancer risk in Mendelian cancer syndromes. PMID: 20399636 Ref: Three-dimensionally specific inhibition of DNA repair-related genes by activated KRAS in colon crypt model. PMID: 20454511 Ref: Aspirin and alterations in DNA repair proteins in the SW480 colorectal cancer cell line. PMID: 20514442 Ref: Mutations in the circadian gene CLOCK in colorectal cancer. PMID: 20551151 Ref: DNA damage-induced cytotoxicity is dissociated from BRCA1's DNA repair function but is dependent on its cytosolic accumulation. PMID: 20631074 Ref: Redox regulation in cancer: a double-edged sword with therapeutic potential. PMID: 20716925 Ref: Genetic profiles distinguish different types of hereditary ovarian cancer. PMID: 20811668 Ref: The rate of the predominant Jewish mutations in the BRCA1, BRCA2, MSH2 and MSH6 genes in unselected Jewish endometrial cancer patients. PMID: 20850175 Ref: BRCA1 mutations and colorectal cancer in Poland. PMID: 20862552 Ref: Epigenetic drivers of genetic alterations. PMID: 20920753 Ref: Screening for common copy-number variants in cancer genes. PMID: 21156252 Ref: Genetic testing and prevention of hereditary cancer at the MMCI--over 10 years of experience. PMID: 21348412 |
Ref: Sporadic breast cancer patients' germline DNA exhibit an AT-rich microsatellite signature. PMID: 21319262 Ref: A p53-independent role for the MDM2 antagonist Nutlin-3 in DNA damage response initiation. PMID: 21338495 Ref: CDC25A, VAV1, TP73, BRCA1 and ZAP70 gene overexpression correlates with radiation response in colorectal cancer. PMID: 21344162 Ref: BARD1 expression predicts outcome in colon cancer. PMID: 21693656 Ref: Drug therapy for hereditary cancers. PMID: 21819606 Ref: Prognostic significance of thymidylate synthase expression in the adjuvant chemotherapy after resection for pulmonary metastases from colorectal cancer. PMID: 21868518 Ref: [Transcriptomic regulation and molecular mechanism of polygenic tumor at different stages]. PMID: 21873780 Ref: Reduced level of ribonucleotide reductase R2 subunits increases dependence on homologous recombination repair of cisplatin-induced DNA damage. PMID: 21875941 Ref: Development and validation of an instrument to measure the impact of genetic testing on self-concept in Lynch syndrome. PMID: 21883167 Ref: Acinar cell carcinoma of the pancreas: new genetic and treatment insights into a rare malignancy. PMID: 22042785 |
Ref: Intraductal papillary mucinous neoplasm of the pancreas: associated cancers, family history, genetic predisposition? PMID: 21975290 Ref: Using tumour pathology to identify people at high genetic risk of breast and colorectal cancers. PMID: 22198256 Ref: Germline DNA copy number variation in familial and early-onset breast cancer. PMID: 22314128 Ref: Epigenetic markers of early tumor development. PMID: 22359284 Ref: Synthetic lethality-based therapeutics: perspectives for applications in colorectal cancer. PMID: 22385509 Ref: Development of a novel approach, the epigenome-based outlier approach, to identify tumor-suppressor genes silenced by aberrant DNA methylation. PMID: 22433712 Ref: Epimutation and cancer: a new carcinogenic mechanism of Lynch syndrome (Review). PMID: 22735547 Ref: Expression of oncogenic BARD1 isoforms affects colon cancer progression and correlates with clinical outcome. PMID: 22814582 Ref: Phenethyl caffeate benzo[kl]xanthene lignan with DNA interacting properties induces DNA damage and apoptosis in colon cancer cells. PMID: 23123449 Ref: Germline truncating-mutations in BRCA1 and MSH6 in a patient with early onset endometrial cancer. PMID: 23164213 |
Ref: Calibration of multiple in silico tools for predicting pathogenicity of mismatch repair gene missense substitutions. PMID: 22949387 Ref: Decreased FANCJ caused by 5FU contributes to the increased sensitivity to oxaliplatin in gastric cancer cells. PMID: 22968820 Ref: Novel DNA damage checkpoints mediating cell death induced by the NEDD8-activating enzyme inhibitor MLN4924. PMID: 23100467 Ref: HOXB13 G84E mutation in Finland: population-based analysis of prostate, breast, and colorectal cancer risk. PMID: 23292082 Ref: Role of conventional chemosensitivity test and tissue biomarker expression in predicting response to treatment of peritoneal carcinomatosis from colon cancer. PMID: 23332421 Ref: BRCA1 and ERCC1 mRNA levels are associated with lymph node metastasis in Chinese patients with colorectal cancer. PMID: 23496813 Ref: Genotyping by induced Forster Resonance Energy Transfer(iFRET) mechanism and simultaneous mutation scanning. PMID: 23520118 Ref: Spinophilin loss correlates with poor patient prognosis in advanced stages of colon carcinoma. PMID: 23729363 Ref: Knowledge, attitudes and behavior of physicians regarding predictive genetic tests for breast and colorectal cancer. PMID: 23827720 Ref: Role of calcium sensing receptor (CaSR) in tumorigenesis. PMID: 23856272 Ref: Lack of referral for genetic counseling and testing in BRCA1/2 and Lynch syndromes: a nationwide study based on 240,134 consultations and 134,652 genetic tests. PMID: 23974829 Ref: Keratin23 (KRT23) knockdown decreases proliferation and affects the DNA damage response of colon cancer cells. PMID: 24039993 Ref: Translating genomics in cancer care. PMID: 24225968 Ref: [Multiple primary malignancies in BRCA1 mutation carriers--two clinical cases]. PMID: 24273914 |
Ref: Epigenetic inactivation of the BRCA1 interactor SRBC and resistance to oxaliplatin in colorectal cancer. PMID: 24273214 Ref: Cinnamaldehyde/chemotherapeutic agents interaction and drug-metabolizing genes in colorectal cancer. PMID: 24276478 Ref: Incidence of colorectal cancer in BRCA1 and BRCA2 mutation carriers: results from a follow-up study. PMID: 24292448 Ref: Mismatch repair deficiency in ovarian cancer -- molecular characteristics and clinical implications. PMID: 24333356 Ref: Is there a link between ovarian cancer and tooth agenesis? PMID: 24631698 Ref: Genetics of endometrial cancer. PMID: 24838932 Ref: CSNK1E/CTNNB1 are synthetic lethal to TP53 in colorectal cancer and are markers for prognosis. PMID: 24947187 Ref: [Hereditary predisposition to cancers of the digestive tract, breast, gynecological and gonadal: focus on the Peutz-Jeghers]. PMID: 25036236 Ref: Up-regulation of the interferon-related genes in BRCA2 knockout epithelial cells. PMID: 25043256 Ref: Risk-benefit assessment of the combined oral contraceptive pill in women with a family history of female cancer. PMID: 25146351 Ref: [Genotyping of BRCA1, BRCA2 and CHEK2 germline mutations in Russian breast cancer patients using diagnostic biochips]. PMID: 25850293 |
Ref: BRCA1 and BRCA2 mutations and the risk for colorectal cancer. PMID: 25195694 Ref: Society of Gynecologic Oncology statement on risk assessment for inherited gynecologic cancer predispositions. PMID: 25238946 Ref: Suppression of homologous recombination sensitizes human tumor cells to IGF-1R inhibition. PMID: 25388513 Ref: Tissue-specific selection of optimal reference genes for expression analysis of anti-cancer drug-related genes in tumor samples using quantitative real-time RT-PCR. PMID: 25445497 Ref: Prevalence of germline mutations in cancer predisposition genes in patients with pancreatic cancer. PMID: 25479140 Ref: Modeling the study of DNA damage responses in mice. PMID: 25636482 Ref: Association of HPV with genetic and epigenetic alterations in colorectal adenocarcinoma from Indian population. PMID: 25647260 Ref: Treatment with the PARP inhibitor, niraparib, sensitizes colorectal cancer cell lines to irinotecan regardless of MSI/MSS status. PMID: 25685067 Ref: A 12-year experience at a tertiary hospital on patients with multiple primary malignant neoplasms. PMID: 25778335 Ref: Psychosocial Impact of Lynch Syndrome on Affected Individuals and Families. PMID: 25786861 Ref: miRNA-26b Overexpression in Ulcerative Colitis-associated Carcinogenesis. PMID: 26083618 Ref: BRCA1 5382insC founder mutation has not a significative recurrent presence in Northeastern Romanian cancer patients. PMID: 26193202 Ref: A 2015 update on predictive molecular pathology and its role in targeted cancer therapy: a review focussing on clinical relevance. PMID: 26358176 Ref: SNP Regulation of microRNA Expression and Subsequent Colon Cancer Risk. PMID: 26630397 |
Ref: The putative oncogene CEP72 inhibits the mitotic function of BRCA1 and induces chromosomal instability. PMID: 26300001 Ref: ROBO1 deletion as a novel germline alteration in breast and colorectal cancer patients. PMID: 26427657 Ref: Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. PMID: 26681312 Ref: Improving performance of multigene panels for genomic analysis of cancer predisposition. PMID: 26845104 Ref: Chromosomal microarray provides enhanced targetable gene aberration detection when paired with next generation sequencing panel in profiling lung and colorectal tumors. PMID: 26880400 Ref: BRD7: a novel tumor suppressor gene in different cancers. PMID: 27158366 Ref: B7-H3 upregulates BRCC3 expression, antagonizing DNA damage caused by 5-Fu. PMID: 27175567 Ref: Expression of an Oncogenic BARD1 Splice Variant Impairs Homologous Recombination and Predicts Response to PARP-1 Inhibitor Therapy in Colon Cancer. PMID: 27197561 Ref: Screening for germline BRCA1, BRCA2, TP53 and CHEK2 mutations in families at-risk for hereditary breast cancer identified in a population-based study from Southern Brazil. PMID: 27223485 Ref: Cytotoxic and targeted therapy for hereditary cancers. PMID: 27555886 Ref: N-end rule pathway inhibition assists colon tumor regression via necroptosis. PMID: 27556106 Ref: Two novel sequence variants in MSH2 gene in a patient who underwent cancer genetic counseling for a very early-onset epithelial ovarian cancer. PMID: 27602174 Ref: A 19-Gene expression signature as a predictor of survival in colorectal cancer. PMID: 27609023 Ref: Familial prostate cancer. PMID: 27899188 |
Ref: Breast cancer risk and clinical implications for germline PTEN mutation carriers. PMID: 26700035 Ref: Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer. PMID: 27978560 Ref: Molecular Portrait of Metastasis-Competent Circulating Tumor Cells in Colon Cancer Reveals the Crucial Role of Genes Regulating Energy Metabolism and DNA Repair. PMID: 28007957 Ref: Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer. PMID: 28135145 Ref: High-risk epithelial ovarian cancer patients for hereditary ovarian cancer. PMID: 28188963 Ref: Identification of differentially expressed genes and their upstream regulators in colorectal cancer. PMID: 28409560 Ref: Application of Panel-Based Tests for Inherited Risk of Cancer. PMID: 28504904 Ref: Frequency of Germline BRCA1/2 Mutations in Unselected Patients With Colorectal Cancer. PMID: 28510492 Ref: Multigene Panel Testing Provides a New Perspective on Lynch Syndrome. PMID: 28514183 Ref: The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer. PMID: 28675510 Ref: BRCA1 expression serves a role in vincristine resistance in colon cancer cells. PMID: 28693174 Ref: Investigating MicroRNA and transcription factor co-regulatory networks in colorectal cancer. PMID: 28865443 Ref: Implementation and utilization of the molecular tumor board to guide precision medicine. PMID: 28915716 Ref: Bioinformatics analysis of SRSF1-controlled gene networks in colorectal cancer. PMID: 29113173 Ref: Targeted next generation sequencing in Chinese colorectal cancer patients guided anti-EGFR treatment and facilitated precision cancer medicine. PMID: 29285234 |
Ref: Germline Genetic Features of Young Individuals With Colorectal Cancer. PMID: 29146522 Ref: Phenotypic characteristics of colorectal cancer in BRCA1/2 mutation carriers. PMID: 29321669 Ref: Prediction of novel target genes and pathways involved in bevacizumab-resistant colorectal cancer. PMID: 29342159 Ref: Immune Profiling of Premalignant Lesions in Patients With Lynch Syndrome. PMID: 29710228 Ref: Inhibiting homologous recombination decreases extrachromosomal amplification but has no effect on intrachromosomal amplification in methotrexate-resistant colon cancer cells. PMID: 30070702 Ref: The BRCA1 exon 13 duplication: clinical characteristics of 22 families in Northern Sweden. PMID: 30136106 Ref: Repurposing of mTOR Complex inhibitors Attenuates MCL-1 and sensitizes to PARP inhibition. PMID: 30201826 Ref: BRCA1 and BRCA2 Gene Mutations and Colorectal Cancer Risk: Systematic Review and Meta-analysis. PMID: 30380096 |