Primary Site >> Pancreatic Cancer
Gene >> BNIP3
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Ref: Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer. PMID: 15289340 |
Ref: Intrinsic chemoresistance to gemcitabine is associated with decreased expression of BNIP3 in pancreatic cancer. PMID: 15837765 Ref: Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis. PMID: 15856026 Ref: Upregulation of BNIP3 by 5-aza-2'-deoxycytidine sensitizes pancreatic cancer cells to hypoxia-mediated cell death. PMID: 15942716 |
Ref: Regulation of BNIP3 in normal and cancer cells. PMID: 16511341 |
Ref: S100A4 contributes to the suppression of BNIP3 expression, chemoresistance, and inhibition of apoptosis in pancreatic cancer. PMID: 17638890 Ref: Elucidation of the relationship of BNIP3 expression to gemcitabine chemosensitivity and prognosis. PMID: 17729412 Ref: The role of the hypoxia-inducible BH3-only proteins BNIP3 and BNIP3L in cancer. PMID: 17805942 |
Ref: Antagonism of E2F-1 regulated Bnip3 transcription by NF-kappaB is essential for basal cell survival. PMID: 19088195 |
Ref: Confirmation of DNA microarray-derived differentially expressed genes in pancreatic cancer using quantitative RT-PCR. PMID: 19657213 Ref: The HIF1alpha-inducible pro-cell death gene BNIP3 is a novel target of SIM2s repression through cross-talk on the hypoxia response element. PMID: 19668230 |
Ref: Examination of apoptosis signaling in pancreatic cancer by computational signal transduction analysis. PMID: 20808857 |
Ref: Silencing of BNIP3 results from promoter methylation by DNA methyltransferase 1 induced by the mitogen-activated protein kinase pathway. PMID: 21573703 |
Ref: Molecular evidence for increased antitumor activity of gemcitabine in combination with a cyclin-dependent kinase inhibitor, P276-00 in pancreatic cancers. PMID: 22873289 |
Ref: Effect of Jinlong capsule on proliferation and apoptosis of human pancreatic cancer cells BxPC-3. PMID: 23789218 Ref: Gossypol and an HMT G9a inhibitor act in synergy to induce cell death in pancreatic cancer cells. PMID: 23807219 |
Ref: MicroRNA-148b and microRNA-152 reactivate tumor suppressor genes through suppression of DNA methyltransferase-1 gene in pancreatic cancer cell lines. PMID: 24448385 |
Ref: Metabolic phenotypes in pancreatic cancer. PMID: 25719198 |
Ref: Predicting the Grade of Dysplasia of Pancreatic Cystic Neoplasms Using Cyst Fluid DNA Methylation Markers. PMID: 28148542 Ref: Inhibition of Isoprenylcysteine Carboxylmethyltransferase Induces Cell-Cycle Arrest and Apoptosis through p21 and p21-Regulated BNIP3 Induction in Pancreatic Cancer. PMID: 28167504 Ref: MiR-377 reverses cancerous phenotypes of pancreatic cells via suppressing DNMT1 and demethylating tumor suppressor genes. PMID: 28758420 |