Primary Site >> Biliary tract Cancer
Gene >> BMI1
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Ref: Over-expression of polycomb group protein EZH2 relates to decreased expression of p16 INK4a in cholangiocarcinogenesis in hepatolithiasis. PMID: 18393368 Ref: The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma. PMID: 18591938 |
Ref: Polycomb group protein Bmi1 is overexpressed and essential in anchorage-independent colony formation, cell proliferation and repression of cellular senescence in cholangiocarcinoma: tissue and culture studies. PMID: 19695678 |
Ref: Inflammation-related DNA damage and expression of CD133 and Oct3/4 in cholangiocarcinoma patients with poor prognosis. PMID: 23917144 Ref: Elevated expression of Bmi1 in hepatocellular carcinoma with bile duct tumor thrombi. PMID: 24719948 |
Ref: Expression profile of microRNA-200 family in hepatocellular carcinoma with bile duct tumor thrombus. PMID: 24135722 |
Ref: Long non-coding RNA CCAT1 promotes gallbladder cancer development via negative modulation of miRNA-218-5p. PMID: 25569100 Ref: Histone Deacetylase Inhibitors Inhibit the Proliferation of Gallbladder Carcinoma Cells by Suppressing AKT/mTOR Signaling. PMID: 26287365 |
Ref: The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cells. PMID: 26623561 Ref: Dysregulation of Bmi1 promotes malignant transformation of hepatic progenitor cells. PMID: 26926789 |