Primary Site >> Colorectal Cancer

Gene >> BLM

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Ref: Differential sensitivity of various human tumors to inhibition of polyamine biosynthesis in vivo.
PMID: 1985877
Ref: In vivo circumvention of human colon carcinoma resistance to bleomycin.
PMID: 1374681
Ref: [A case of elderly Hashimoto disease presenting malignant lymphoma, gastric cancer and colon cancer].
PMID: 8295359
Ref: Bloom's Syndrome
PMID: 20301572
Ref: Numerous colonic adenomas in an individual with Bloom's syndrome.
PMID: 11487553
Ref: BLM heterozygosity and the risk of colorectal cancer.
PMID: 12242432
Ref: Heterozygosity for the BLM(Ash) mutation and cancer risk.
PMID: 12702560
Ref: Hyper-recombination and genetic instability in BLM-deficient epithelial cells.
PMID: 14695165
Ref: Localization of cancer susceptibility genes by genome-wide single-nucleotide polymorphism linkage-disequilibrium mapping.
PMID: 15520224
Ref: Coinheritance of BRCA1 and BRCA2 mutations with Fanconi anemia and Bloom syndrome mutations in Ashkenazi Jewish population: possible role in risk modification for cancer development.
PMID: 15726604
Ref: Clinical and genetic findings in an Ashkenazi Jewish population with colorectal neoplasms.
PMID: 15959913
Ref: 4-nitroquinoline-1-oxide induces the formation of cellular topoisomerase I-DNA cleavage complexes.
PMID: 16818625
Ref: Prevalence of breast and colorectal cancer in Ashkenazi Jewish carriers of Fanconi anemia and Bloom syndrome.
PMID: 18210922
Ref: Deficiency of Bloom syndrome helicase activity is radiomimetic.
PMID: 18787401
Ref: Colorectal cancer and polymorphisms in DNA repair genes WRN, RMI1 and BLM.
PMID: 19945966
Ref: Altered RECQ Helicase Expression in Sporadic Primary Colorectal Cancers.
PMID: 23908689
Ref: Tailoring heated intraperitoneal mitomycin C for peritoneal metastases originating from colorectal carcinoma: a translational approach to improve survival.
PMID: 25668003
Ref: Targeting SOD1 induces synthetic lethal killing in BLM- and CHEK2-deficient colorectal cancer cells.
PMID: 26318585
Ref: Deleterious Germline BLM Mutations and the Risk for Early-onset Colorectal Cancer.
PMID: 26358404
Ref: The risk for developing cancer in Israeli ATM, BLM, and FANCC heterozygous mutation carriers.
PMID: 26778106
Ref: Adenocarcinoma of the Right Colon in a Patient with Bloom Syndrome.
PMID: 27597923
Ref: Aberrant BLM cytoplasmic expression associates with DNA damage stress and hypersensitivity to DNA-damaging agents in colorectal cancer.
PMID: 27169843
Ref: Colorectal and Endometrial Cancer Risk and Age at Diagnosis in BLMAsh Mutation Carriers.
PMID: 28647934
Ref: miR-522-3p Promotes Tumorigenesis in Human Colorectal Cancer via Targeting Bloom Syndrome Protein.
PMID: 29386092
Ref: Nanocarrier Composed of Magnetite Core Coated with Three Polymeric Shells Mediates LCS-1 Delivery for Synthetic Lethal Therapy of BLM-Defective Colorectal Cancer Cells.
PMID: 29451980