Primary Site >> Colorectal Cancer
Gene >> BIRC5
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Ref: The inhibitors of apoptosis (IAPs) and their emerging role in cancer. PMID: 9916987 |
Ref: Expression of the antiapoptosis gene, survivin, predicts death from recurrent colorectal carcinoma. PMID: 10764707 Ref: Antibody response to the tumor-associated inhibitor of apoptosis protein survivin in cancer patients. PMID: 10766164 Ref: Survival of colorectal cancer cell lines treated with paclitaxel, radiation, and 5-FU: effect of TP53 or hMLH1 deficiency. PMID: 10993958 Ref: Tamoxifen and gonadal steroids inhibit colon cancer growth in association with inhibition of thymidylate synthase, survivin and telomerase expression through estrogen receptor beta mediated system. PMID: 11078914 |
Ref: Expression of survivin in normal, hyperplastic, and neoplastic colonic mucosa. PMID: 11172305 Ref: Immunohistochemical detection of the anti-apoptosis protein, survivin, predicts survival after curative resection of stage II colorectal carcinomas. PMID: 11352303 Ref: Cancer gene therapy using a survivin mutant adenovirus. PMID: 11581299 Ref: Evidence that APC regulates survivin expression: a possible mechanism contributing to the stem cell origin of colon cancer. PMID: 11751382 |
Ref: Downregulation of survivin expression by induction of the effector cell protease receptor-1 reduces tumor growth potential and results in an increased sensitivity to anticancer agents in human colon cancer. PMID: 12441269 |
Ref: Identification and validation of genes involved in the pathogenesis of colorectal cancer using cDNA microarrays and RNA interference. PMID: 12631590 Ref: Expression of survivin protein in human colorectal carcinogenesis. PMID: 12717841 Ref: Survivin and molecular pathogenesis of colorectal cancer. PMID: 12885482 Ref: The apoptosis inhibitor protein survivin induces tumor-specific CD8+ and CD4+ T cells in colorectal cancer patients. PMID: 12907624 Ref: Induction of cIAP-2 in human colon cancer cells through PKC delta/NF-kappa B. PMID: 14527959 Ref: Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: implication for cancer specific therapy. PMID: 14583479 Ref: Recursive partitioning as an approach to selection of immune markers for tumor diagnosis. PMID: 14613989 Ref: [Development of a novel gene therapy using survivin antisense expressing adenoviral vectors]. PMID: 14619525 Ref: Interferon-gamma-induced sensitization of colon carcinomas to ZD9331 targets caspases, downstream of Fas, independent of mitochondrial signaling and the inhibitor of apoptosis survivin. PMID: 14695155 Ref: [Predictive molecular marker of distant metastasis in colorectal cancer]. PMID: 15027705 |
Ref: Correspondence re: T. Zhang et al., Evidence that APC regulates survivin expression: a possible mechanism contributing to the stem cell origin of colon cancer. Cancer Res., 61: 8664-8667, 2001. PMID: 14744799 Ref: Survivin enhances Fas ligand expression via up-regulation of specificity protein 1-mediated gene transcription in colon cancer cells. PMID: 15004200 Ref: [Expression and clinical significance of survivin gene and PTEN protein in colorectal adenocarcinoma]. PMID: 15025964 Ref: Molecular characterizations of derivatives of HCT116 colorectal cancer cells that are resistant to the chemotherapeutic agent 5-fluorouracil. PMID: 15067352 Ref: Phase I clinical study of anti-apoptosis protein, survivin-derived peptide vaccine therapy for patients with advanced or recurrent colorectal cancer. PMID: 15193151 Ref: Expression of survivin and its significance in colorectal cancer. PMID: 15334693 Ref: Survivin expression is an independent prognostic factor in rectal cancer patients with and without preoperative radiotherapy. PMID: 15337550 Ref: Angiotensin II activates MAP kinase and NF-kappaB through angiotensin II type I receptor in human pancreatic cancer cells. PMID: 15375532 Ref: Colonic crypt changes during adenoma development in familial adenomatous polyposis: immunohistochemical evidence for expansion of the crypt base cell population. PMID: 15509520 Ref: [Expression and significance of survivin in colon cancer]. PMID: 15566647 Ref: [Expression of survivin and its clinical significance in colorectal carcinoma]. PMID: 15604073 |
Ref: [Clinical significance of survivin expression in colorectal cancer and its relationship with cell apoptosis and angiogenesis]. PMID: 15642214 Ref: Modulation of IMPDH2, survivin, topoisomerase I and vimentin increases sensitivity to methotrexate in HT29 human colon cancer cells. PMID: 15670151 Ref: Gene therapy for colon cancer by adeno-associated viral vector-mediated transfer of survivin Cys84Ala mutant. PMID: 15685548 Ref: A potent immunogenic general cancer vaccine that targets survivin, an inhibitor of apoptosis proteins. PMID: 15746049 Ref: Survivin enhances telomerase activity via up-regulation of specificity protein 1- and c-Myc-mediated human telomerase reverse transcriptase gene transcription. PMID: 15817155 Ref: [Study of immunological effect of dendritic cell transfected with survivin gene on the specific anti-alimentary tract tumor]. PMID: 15842941 Ref: Autoimmune response to anti-apoptotic protein survivin and its association with antibodies to p53 and c-myc in cancer detection. PMID: 15896923 Ref: Cellular localisation of survivin: impact on the prognosis in colorectal cancer. PMID: 15902487 Ref: Activation of p53-dependent apoptosis by acute ablation of glycogen synthase kinase-3beta in colorectal cancer cells. PMID: 15958644 Ref: Systemic treatment with tetra-O-methyl nordihydroguaiaretic acid suppresses the growth of human xenograft tumors. PMID: 15958646 Ref: DNA-based vaccines activate innate and adaptive antitumor immunity by engaging the NKG2D receptor. PMID: 16040807 Ref: Expression of a novel apoptosis inhibitor-survivin in colorectal carcinoma. PMID: 16094711 Ref: Cancer-specific gene therapy. PMID: 16096014 Ref: [Antisense RNA targeting survivin enhances the chemosensitivity of LOVO/Adr cells to taxotere]. PMID: 16224667 Ref: High hRFI expression correlates with resistance to fluoropyrimidines in human colon cancer cell lines and in xenografts. PMID: 16270526 Ref: Survivin expression in colorectal adenocarcinoma using tissue microarray. PMID: 16353082 |
Ref: A retrogen plasmid-based vaccine generates high titer antibody responses against the autologous cancer antigen survivin and demonstrates anti-tumor efficacy. PMID: 16019131 Ref: A comparative study of the expression of Wnt-1, WISP-1, survivin and cyclin-D1 in colorectal carcinoma. PMID: 16041507 Ref: The blockage of survivin and securin expression increases the cytochalasin B-induced cell death and growth inhibition in human cancer cells. PMID: 16219911 Ref: Overexpression of thymosin beta-4 renders SW480 colon carcinoma cells more resistant to apoptosis triggered by FasL and two topoisomerase II inhibitors via downregulating Fas and upregulating Survivin expression, respectively. PMID: 16364925 Ref: Centrosome-, chromosomal-passenger- and cell-cycle-associated mRNAs are differentially regulated in the development of sporadic colorectal cancer. PMID: 16402339 Ref: Mitosis-independent survivin gene expression in vivo and regulation by p53. PMID: 16585159 Ref: Casein kinase 2 (CK2) increases survivin expression via enhanced beta-catenin-T cell factor/lymphoid enhancer binding factor-dependent transcription. PMID: 17005722 Ref: Correlation of microsatellite status, proliferation, apoptotic and selected immunohistochemical markers in colorectal carcinoma studied with tissue microarray. PMID: 17019973 Ref: Suppression of colorectal tumor growth by regulated survivin targeting. PMID: 17077982 Ref: [Influence and significance of preoperative intraarterial infusion chemotherapy combined with radiotherapy on survivin, p53 and Bax expression in low rectal carcinoma]. PMID: 17094914 Ref: Gene expression levels of epidermal growth factor receptor, survivin, and vascular endothelial growth factor as molecular markers of lymph node involvement in patients with locally advanced rectal cancer. PMID: 17241515 Ref: Down-regulation of FHIT inhibits apoptosis of colorectal cancer: mechanism and clinical implication. PMID: 17382535 |
Ref: Survivin and Cyclooxygenase-2 are co-expressed in human and mouse colon carcinoma and in terminally differentiated colonocytes. PMID: 17128412 Ref: Docosahexaenoic acid induces proteasome-dependent degradation of beta-catenin, down-regulation of survivin and apoptosis in human colorectal cancer cells not expressing COX-2. PMID: 17183061 Ref: Survivin depletion preferentially reduces the survival of activated K-Ras-transformed cells. PMID: 17237286 Ref: STAT3 mRNA and protein expression in colorectal cancer: effects on STAT3-inducible targets linked to cell survival and proliferation. PMID: 17264243 Ref: Effects of garcinol and its derivatives on intestinal cell growth: Inhibitory effects and autoxidation-dependent growth-stimulatory effects. PMID: 17382202 Ref: Suppression of FHL2 expression induces cell differentiation and inhibits gastric and colon carcinogenesis. PMID: 17383428 Ref: The forkhead box M1 transcription factor contributes to the development and growth of mouse colorectal cancer. PMID: 17408638 Ref: Activation of p38 mitogen-activated protein kinase by celecoxib oppositely regulates survivin and gamma-H2AX in human colorectal cancer cells. PMID: 17540426 Ref: [Expression of survivin in colorectal adenoma and adenocarcinoma]. PMID: 17633470 Ref: Cell-cycle and apoptosis regulators (p16INK4A, p21CIP1, beta-catenin, survivin, and hTERT) and morphometry-defined MPECs predict metachronous cancer development in colorectal adenoma patients. PMID: 17641414 Ref: E-cadherin is required for caveolin-1-mediated down-regulation of the inhibitor of apoptosis protein survivin via reduced beta-catenin-Tcf/Lef-dependent transcription. PMID: 17785436 Ref: [Effect of lipoteichoic acid of Bifidobacterium on survivin and its regulatory genes]. PMID: 17892124 Ref: The universal character of the tumor-associated antigen survivin. PMID: 17947459 Ref: Predictive molecular markers for colorectal cancer patients with resected liver metastasis and adjuvant chemotherapy. PMID: 18054556 Ref: [The study in lasting effectivity on conditionally replicating adenovirus shRNA mediating survivin gene silencing in colon carcinoma cell line HT-29]. PMID: 18095587 Ref: Influence of survivin-targeted siRNA on the biological features of colorectal carcinoma cells. PMID: 24573871 |
Ref: Survivin, p53, and Ki-67 as predictors of histopathologic response in locally advanced rectal cancer treated with preoperative chemoradiotherapy. PMID: 17805549 Ref: Differential sensitivity of human colon cancer cell lines to the nucleoside analogs ARC and DRB. PMID: 17999411 Ref: WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: identification of topoisomerase II inhibition and apoptotic machinery in prostate cancers. PMID: 18035333 Ref: Metachronous cancer development in patients with sporadic colorectal adenomas-multivariate risk model with independent and combined value of hTERT and survivin. PMID: 18189140 Ref: [Specific killing effects of combination of recombinant adenovirus containing double suicide gene driven by KDR promoter and survivin antisense oligonucleotide on colorectal cancer cells and vascular endothelial cells]. PMID: 18197498 Ref: Distinct expression pattern of the full set of secreted phospholipases A2 in human colorectal adenocarcinomas: sPLA2-III as a biomarker candidate. PMID: 18212756 Ref: Survivin antisense oligonucleotides effectively radiosensitize colorectal cancer cells in both tissue culture and murine xenograft models. PMID: 18406888 Ref: Transforming growth factor beta induces apoptosis through repressing the phosphoinositide 3-kinase/AKT/survivin pathway in colon cancer cells. PMID: 18451140 Ref: Bortezomib (Velcade) induces p27Kip1 expression through S-phase kinase protein 2 degradation in colorectal cancer. PMID: 18451165 Ref: Anticancer effect of SN-38 on colon cancer cell lines with different metastatic potential. PMID: 18497955 Ref: The influence of survivin shRNA on the cell cycle and the invasion of SW480 cells of colorectal carcinoma. PMID: 18637206 Ref: T-cell responses to survivin in cancer patients undergoing radiation therapy. PMID: 18676762 Ref: Loss of cannabinoid receptor 1 accelerates intestinal tumor growth. PMID: 18676872 Ref: Role of Hypoxia-inducible factor-1 alpha and Survivin in colorectal carcinoma progression. PMID: 18704463 Ref: Evaluation of the immunohistochemical stain patterns of survivin, Bak and Bag-1 in colorectal cancers and comparison with polyps situated in the colon. PMID: 18795671 Ref: Quantitative real-time RT-PCR detection for survivin, CK20 and CEA in peripheral blood of colorectal cancer patients. PMID: 18845519 Ref: A survivin specific T-cell clone from a breast cancer patient display universal tumor cell lysis. PMID: 18927499 Ref: Impact of oxaliplatin and a novel DACH-platinum complex in the gene expression of HCT116 colon cancer cells. PMID: 18949432 Ref: Inhibition of serine-peptidase activity enhances the generation of a survivin-derived HLA-A2-presented CTL epitope in colon-carcinoma cells. PMID: 19000094 Ref: [Polyamidoamine dendrimer-mediated survivin antisense oligonucleotide inhibits the growth of subcutaneously transplanted colorectal cancer in nude mice]. PMID: 19033096 |
Ref: Calcium and calcium sensing receptor modulates the expression of thymidylate synthase, NAD(P)H:quinone oxidoreductase 1 and survivin in human colon carcinoma cells: promotion of cytotoxic response to mitomycin C and fluorouracil. PMID: 18618519 Ref: Calcium, calcium-sensing receptor and colon cancer. PMID: 18725175 Ref: Survivin plays as a resistant factor against tamoxifen-induced apoptosis in human breast cancer cells. PMID: 18815881 Ref: High expression of Foxp3, IL-23p19 and survivin mRNA in colorectal carcinoma. PMID: 18825388 Ref: Survivin -31G/C promoter polymorphism and sporadic colorectal cancer. PMID: 18946675 Ref: Clinical, pathologic, and molecular features of early-onset colorectal carcinoma. PMID: 19047896 Ref: Small molecule inhibitors of WNT signaling effectively induce apoptosis in acute myeloid leukemia cells. PMID: 19067737 Ref: Induction of apoptosis of human colon cancer cells by siRNA recombinant expression vector targeting survivin gene. PMID: 19224161 Ref: Caveolin-1-mediated suppression of cyclooxygenase-2 via a beta-catenin-Tcf/Lef-dependent transcriptional mechanism reduced prostaglandin E2 production and survivin expression. PMID: 19244345 Ref: Synergistic inhibition effect of tumor growth by using celecoxib in combination with oxaliplatin. PMID: 19387877 Ref: Elevated expressions of MMP7, TROP2, and survivin are associated with survival, disease recurrence, and liver metastasis of colon cancer. PMID: 19421758 Ref: Quercetin inhibit human SW480 colon cancer growth in association with inhibition of cyclin D1 and survivin expression through Wnt/beta-catenin signaling pathway. PMID: 19440933 Ref: Peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of Embelin on colon carcinogenesis. PMID: 19458067 Ref: 3,3'-diindolylmethane enhances the efficacy of butyrate in colon cancer prevention through down-regulation of survivin. PMID: 19470789 Ref: Detection of survivin-expressing circulating cancer cells in the peripheral blood of patients with esophageal squamous cell carcinoma and its clinical significance. PMID: 19521785 Ref: Immunoexpression of inhibitors of apoptosis proteins and their antagonist SMAC/DIABLO in colorectal carcinoma: correlation with apoptotic index, cellular proliferation and prognosis. PMID: 19578769 Ref: Significance of an exon 2 G4C14-to-A4T14 polymorphism in the p73 gene on survival in rectal cancer patients with or without preoperative radiotherapy. PMID: 19581013 Ref: Oncogenic microRNA-27a is a target for anticancer agent methyl 2-cyano-3,11-dioxo-18beta-olean-1,12-dien-30-oate in colon cancer cells. PMID: 19582879 Ref: Increased spontaneous apoptosis, but not survivin expression, is associated with histomorphologic response to neoadjuvant chemoradiation in rectal cancer. PMID: 19593573 Ref: pRb2/p130 protein in relation to clinicopathological and biological variables in rectal cancers with a clinical trial of preoperative radiotherapy. PMID: 19597825 Ref: [Apoptosis induction effect of siRNA recombinant expression vector targeting Livin and Survivin gene simultaneously on human colon cancer cells]. PMID: 19598029 Ref: Enhanced chemotherapy sensitivity of human colon cancer cells to 5-fluorouracil by siRNA recombinant expression vector targeting survivin gene. PMID: 19618606 Ref: Intracellular localization of survivin determines biological behavior in colorectal cancer. PMID: 19639203 Ref: Up-regulation of Kruppel-like factor 5 in pancreatic cancer is promoted by interleukin-1beta signaling and hypoxia-inducible factor-1alpha. PMID: 19671674 Ref: [Expression and clinical significance of survivin and matrix metalloproteinase-7 in colon cancer]. PMID: 19728912 Ref: DcR3 and survivin are highly expressed in colorectal carcinoma and closely correlated to its clinicopathologic parameters. PMID: 19735100 Ref: [Inhibitory effect of multiple siRNA recombinant expression vector targeting simultaneously Livin and Survivin genes on human colon cancer cells proliferation]. PMID: 19806913 |
Ref: Vitamin D mediates its action in human colon carcinoma cells in a calcium-sensing receptor-dependent manner: downregulates malignant cell behavior and the expression of thymidylate synthase and survivin and promotes cellular sensitivity to 5-FU. PMID: 19621386 Ref: Novel cancer vaccine based on genes of Salmonella pathogenicity island 2. PMID: 19824039 Ref: Reg IV regulates normal intestinal and colorectal cancer cell susceptibility to radiation-induced apoptosis. PMID: 19900450 Ref: Survivin: a potential prognostic marker and chemoradiotherapeutic target for colorectal cancer. PMID: 19921309 Ref: Antitumor effect of mSurvivinThr34-->Ala in murine colon carcinoma when administered intravenously. PMID: 19949901 Ref: Enhanced expression of proproliferative and antiapoptotic genes in ulcerative colitis-associated neoplasia. PMID: 20027603 Ref: Tumor suppressor XIAP-Associated factor 1 (XAF1) cooperates with tumor necrosis factor-related apoptosis-inducing ligand to suppress colon cancer growth and trigger tumor regression. PMID: 20082449 Ref: Expression profiles of proliferative and antiapoptotic genes in sporadic and colitis-related mouse colon cancer models. PMID: 20096072 Ref: Combined analysis of survivin autoantibody and carcinoembryonic antigen biomarkers for improved detection of colorectal cancer. PMID: 20178447 Ref: Efficient co-transduction of adenoviral vectors encoding carcinoembryonic antigen and survivin into dendritic cells by the CAR-TAT adaptor molecule enhance anti-tumor immunity in a murine colorectal cancer model. PMID: 20211203 Ref: Effects of potential calcium sensing receptor inducers on promoting chemosensitivity of human colon carcinoma cells. PMID: 20428782 Ref: Sesamin manifests chemopreventive effects through the suppression of NF-kappa B-regulated cell survival, proliferation, invasion, and angiogenic gene products. PMID: 20460401 Ref: Survivin is regulated by interleukin-4 in colon cancer stem cells. PMID: 20506498 Ref: Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF-kappaB signaling pathway in colon cancer cells. PMID: 20509140 Ref: Lignans inhibit cell growth via regulation of Wnt/beta-catenin signaling. PMID: 20510325 Ref: DHA alters expression of target proteins of cancer therapy in chemotherapy resistant SW620 colon cancer cells. PMID: 20574922 Ref: Silibinin exerts sustained growth suppressive effect against human colon carcinoma SW480 xenograft by targeting multiple signaling molecules. PMID: 20628792 Ref: Cinnamon extract induces tumor cell death through inhibition of NFkappaB and AP1. PMID: 20653974 Ref: Oxaliplatin down-regulates survivin by p38 MAP kinase and proteasome in human colon cancer cells. PMID: 20708607 Ref: Colon tumor cell growth-inhibitory activity of sulindac sulfide and other nonsteroidal anti-inflammatory drugs is associated with phosphodiesterase 5 inhibition. PMID: 20876730 Ref: Oncolytic adenovirus mediated Survivin RNA interference and 5-fluorouracil synergistically suppress the lymphatic metastasis of colorectal cancer. PMID: 20878122 Ref: Survivin-3B gene decreases the invasion-inhibitory effect of colon cancer cells with 5-fluorouracil. PMID: 20939430 Ref: The survivin -31 snp in human colorectal cancer correlates with survivin splice variant expression and improved overall survival. PMID: 20978324 Ref: Survivin-induced Aurora-B kinase activation: A mechanism by which APC mutations contribute to increased mitoses during colon cancer development. PMID: 21057000 Ref: Change in Expression of Survivin Caused by Using Oxaliplatin in HCT116 Colon Cancer Cells. PMID: 21152225 Ref: SiRNA-mediated survivin inhibition enhances chemo- or radiosensivity of colorectal cancer cells in tumor-bearing nude mice. PMID: 21443101 Ref: Effect of hypoxia-inducible factor 1-alpha on Survivin in colorectal cancer. PMID: 21472255 |
Ref: Downregulation of survivin and aurora A by histone deacetylase and RAS inhibitors: a new drug combination for cancer therapy. PMID: 20473860 Ref: Action of SN 28049, a new DNA binding topoisomerase II-directed antitumour drug: comparison with doxorubicin and etoposide. PMID: 20567995 Ref: Failure of downregulation of survivin following neoadjuvant radiochemotherapy in rectal cancer is associated with distant metastases and shortened survival. PMID: 21118954 Ref: GT-094, a NO-NSAID, inhibits colon cancer cell growth by activation of a reactive oxygen species-microRNA-27a: ZBTB10-specificity protein pathway. PMID: 21156786 Ref: Profile of protein expression of the colon cancer cell line SW480 with survivin/shRNA. PMID: 21200325 Ref: Ibuprofen inhibits activation of nuclear {beta}-catenin in human colon adenomas and induces the phosphorylation of GSK-3{beta}. PMID: 21205744 Ref: Apoptotic effect of tolfenamic acid in androgen receptor-independent prostate cancer cell and xenograft tumor through specificity protein 1. PMID: 21241418 Ref: TNFalpha cooperates with IFN-gamma to repress Bcl-xL expression to sensitize metastatic colon carcinoma cells to TRAIL-mediated apoptosis. PMID: 21264227 Ref: Inhibitor of apoptosis protein family as diagnostic markers and therapeutic targets of colorectal cancer. PMID: 21264751 Ref: [Changes in the biological behaviors of colon cancer cells under simulated hypoxia in vitro]. PMID: 21269976 Ref: A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/beta-catenin signaling and colon cancer cell tumorigenesis. PMID: 21321609 Ref: Immunogenic enhancement and clinical effect by type-I interferon of anti-apoptotic protein, survivin-derived peptide vaccine, in advanced colorectal cancer patients. PMID: 21371173 Ref: Nifedipine synergizes with calcium in activating the calcium sensing receptor, suppressing the expression of thymidylate synthase and survivin and promoting sensitivity to fluorouracil in human colon carcinoma cells. PMID: 21374737 Ref: High survivin expression as a predictor of poor response to preoperative chemoradiotherapy in locally advanced rectal cancer. PMID: 21424389 Ref: Survivin isoforms and clinicopathological characteristics in colorectal adenocarcinomas using real-time qPCR. PMID: 21472129 Ref: The survivin -31 snp in human colorectal cancer correlates with survivin splice variant expression and improved overall survival. PMID: 21538024 Ref: P-cadherin promotes liver metastasis and is associated with poor prognosis in colon cancer. PMID: 21703417 Ref: 2-methoxy-5-amino-N-hydroxybenzamide sensitizes colon cancer cells to TRAIL-induced apoptosis by regulating death receptor 5 and survivin expression. PMID: 21817114 Ref: Proliferation-inhibiting and apoptosis-inducing effects of ursolic acid and oleanolic acid on multi-drug resistance cancer cells in vitro. PMID: 21826595 Ref: Expression of the antiapoptotic protein survivin in colon cancer. PMID: 21855041 Ref: Pharmacologic doses of ascorbic acid repress specificity protein (Sp) transcription factors and Sp-regulated genes in colon cancer cells. PMID: 21919647 Ref: Expression of the survivin-2B splice variant related to the progression of colorectal carcinoma. PMID: 22066067 Ref: Gene therapy for C-26 colon cancer using heparin-polyethyleneimine nanoparticle-mediated survivin T34A. PMID: 22072877 Ref: STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH(+)/CD133(+) stem cell-like human colon cancer cells. PMID: 22074823 Ref: REG4, NEIL2, and BIRC5 gene expression correlates with gamma-radiation sensitivity in patients with rectal cancer receiving radiotherapy. PMID: 22199273 Ref: Colorectal cancer stem cells and cell death. PMID: 24212789 |
Ref: Trichostatin A, a histone deacetylase inhibitor, suppresses JAK2/STAT3 signaling via inducing the promoter-associated histone acetylation of SOCS1 and SOCS3 in human colorectal cancer cells. PMID: 21520296 Ref: Chicken skin mucosa surrounding adult colorectal adenomas is a risk factor for carcinogenesis. PMID: 21654311 Ref: Boswellic acid inhibits growth and metastasis of human colorectal cancer in orthotopic mouse model by downregulating inflammatory, proliferative, invasive and angiogenic biomarkers. PMID: 21702037 Ref: Peroxisome proliferator-activated receptor delta confers resistance to peroxisome proliferator-activated receptor gamma-induced apoptosis in colorectal cancer cells. PMID: 21765467 Ref: gamma-Tocotrienol inhibits cell viability through suppression of beta-catenin/Tcf signaling in human colon carcinoma HT-29 cells. PMID: 21852086 Ref: Knockdown of RON inhibits AP-1 activity and induces apoptosis and cell cycle arrest through the modulation of Akt/FoxO signaling in human colorectal cancer cells. PMID: 21901254 Ref: Anti-carcinogenic properties of omeprazole against human colon cancer cells and azoxymethane-induced colonic aberrant crypt foci formation in rats. PMID: 21956158 Ref: Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population. PMID: 22001602 Ref: Overexpression of survivin is correlated with increased invasion and metastasis of colorectal cancer. PMID: 22065492 Ref: Prognostic value of putative circulating cancer stem cells in patients undergoing hepatic resection for colorectal liver metastasis. PMID: 22071867 Ref: Trichostatin A and sirtinol suppressed survivin expression through AMPK and p38MAPK in HT29 colon cancer cells. PMID: 22155142 Ref: SAHA inhibits the growth of colon tumors by decreasing histone deacetylase and the expression of cyclin D1 and survivin. PMID: 22270866 Ref: The expression of MAGE and SSX, and correlation of COX2, VEGF, and survivin in colorectal cancer. PMID: 22287745 Ref: Analysis of cell adhesion during early stages of colon cancer based on an extended multi-valued logic approach. PMID: 22298312 Ref: Treating colon cancer with a suicide gene delivered by self-assembled cationic MPEG-PCL micelles. PMID: 22388488 Ref: Preclinical evaluation of destruxin B as a novel Wnt signaling target suppressing proliferation and metastasis of colorectal cancer using non-invasive bioluminescence imaging. PMID: 22465936 Ref: Single-photon emission computed tomographic imaging of the early time course of therapy-induced cell death using technetium 99m tricarbonyl His-annexin A5 in a colorectal cancer xenograft model. PMID: 22469241 Ref: Chk2 phosphorylation of survivin-DeltaEx3 contributes to a DNA damage-sensing checkpoint in cancer. PMID: 22586065 Ref: Survivin-miRNA-loaded nanoparticles as auxiliary tools for radiation therapy: preparation, characterisation, drug release, cytotoxicity and therapeutic effect on colorectal cancer cells. PMID: 22703230 Ref: Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine. PMID: 22832932 Ref: Increased JNK1 signaling pathway is responsible for ABCG2-mediated multidrug resistance in human colon cancer. PMID: 22870247 Ref: Aspirin inhibits colon cancer cell and tumor growth and downregulates specificity protein (Sp) transcription factors. PMID: 23110215 Ref: Splice isoforms as therapeutic targets for colorectal cancer. PMID: 23118106 Ref: In vivo induction of apoptosis by fucoxanthin, a marine carotenoid, associated with down-regulating STAT3/EGFR signaling in sarcoma 180 (S180) xenografts-bearing mice. PMID: 23118721 Ref: Prognostic and predictive value of circulating tumor cell analysis in colorectal cancer patients. PMID: 23146106 Ref: The prognostic role of disseminated tumor cells detected in peripheral blood and bone marrow of colorectal cancer. PMID: 23178553 Ref: Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs. PMID: 23194063 Ref: Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells. PMID: 23227266 |
Ref: New NSAID targets and derivatives for colorectal cancer chemoprevention. PMID: 22893202 Ref: Survivin expression can predict the effect of chemoradiotherapy for advanced lower rectal cancer. PMID: 22936565 Ref: Isolation and characterization of calcium sensing receptor null cells: a highly malignant and drug resistant phenotype of colon cancer. PMID: 23055106 Ref: Upregulation of the antiapoptotic factor Livin contributes to cisplatin resistance in colon cancer cells. PMID: 23188704 Ref: Evaluation of alpha 1-antitrypsin and the levels of mRNA expression of matrix metalloproteinase 7, urokinase type plasminogen activator receptor and COX-2 for the diagnosis of colorectal cancer. PMID: 23300952 Ref: Suppression of Src/ERK and GSK-3/beta-catenin signaling by pinosylvin inhibits the growth of human colorectal cancer cells. PMID: 23333577 Ref: Oct-4 is required for an antiapoptotic behavior of chemoresistant colorectal cancer cells enriched for cancer stem cells: effects associated with STAT3/Survivin. PMID: 23340171 Ref: 2,3,6-Trisubstituted quinoxaline derivative, a small molecule inhibitor of the Wnt/beta-catenin signaling pathway, suppresses cell proliferation and enhances radiosensitivity in A549/Wnt2 cells. PMID: 23348226 Ref: Cotransfection of survivin and CD44v3 short hairpin RNAs affects proliferation, apoptosis, and invasiveness of colorectal cancer. PMID: 23377575 Ref: microRNA-16 represses colorectal cancer cell growth in vitro by regulating the p53/survivin signaling pathway. PMID: 23380758 Ref: Survivin -31G>C polymorphism and gastrointestinal tract cancer risk: a meta-analysis. PMID: 23405077 Ref: The detergent-soluble cytoplasmic pool of survivin suppresses anoikis and its expression is associated with metastatic disease of human colon cancer. PMID: 23405201 Ref: Synergistic anticancer effects of curcumin and resveratrol in Hepa1-6 hepatocellular carcinoma cells. PMID: 23446753 Ref: Expression of survivin and its four splice variants in colorectal cancer and its clinical significances. PMID: 23494669 Ref: Decrease of survivin, p53 and Bcl-2 expression in chemorefractory colorectal liver metastases may be predictive of radiosensivity radiosensivity after radioembolization with yttrium-90 resin microspheres. PMID: 23497522 Ref: Resveratrol and quercetin in combination have anticancer activity in colon cancer cells and repress oncogenic microRNA-27a. PMID: 23530649 Ref: Polymorphisms of survivin and its protein expression are associated with colorectal cancer susceptibility in Chinese population. PMID: 23581553 Ref: A survivin-associated adaptive response in radiation therapy. PMID: 23651635 Ref: Induction of CaSR expression circumvents the molecular features of malignant CaSR null colon cancer cells. PMID: 23674327 Ref: Prognostic and clinicopathological significance of survivin in colorectal cancer: a meta-analysis. PMID: 23755220 Ref: Teng-Long-Bu-Zhong-Tang, a Chinese herbal formula, enhances anticancer effects of 5--Fluorouracil in CT26 colon carcinoma. PMID: 23758730 Ref: Effect of curcumin on human colon cancer multidrug resistance in vitro and in vivo. PMID: 23778405 Ref: Functional role and therapeutic potential of the pim-1 kinase in colon carcinoma. PMID: 23814490 Ref: Molecular pathways: MERTK signaling in cancer. PMID: 23833304 Ref: Antitumor activity of 2-hydroxycinnamaldehyde for human colon cancer cells through suppression of beta-catenin signaling. PMID: 23855266 Ref: The prognostic value of survivin expression in patients with colorectal carcinoma: a meta-analysis. PMID: 23894202 Ref: Potential targets for colorectal cancer prevention. PMID: 23975167 Ref: SIRT1 Expression Is Associated with Good Prognosis in Colorectal Cancer. PMID: 24009628 Ref: The cannabinoid WIN 55,212-2 decreases specificity protein transcription factors and the oncogenic cap protein eIF4E in colon cancer cells. PMID: 24030632 Ref: Expression of cell cycle regulatory factors hus1, gadd45a, rb1, cdkn2a and mre11a correlates with expression of clock gene per2 in human colorectal carcinoma tissue. PMID: 24062075 Ref: The prognostic value of the apoptosis pathway in colorectal cancer: a review of the literature on biomarkers identified by immunohistochemistry. PMID: 24179395 Ref: An APC:WNT Counter-Current-Like Mechanism Regulates Cell Division Along the Human Colonic Crypt Axis: A Mechanism That Explains How APC Mutations Induce Proliferative Abnormalities That Drive Colon Cancer Development. PMID: 24224156 Ref: Tumorigenesis and tumor progression related gene expression profiles in colorectal cancer. PMID: 24240588 Ref: Immunohistochemical expression of nuclear and cytoplasmic survivin in gastrointestinal carcinoma. PMID: 24294379 |
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