Primary Site >> Colorectal Cancer

Gene >> BIK

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Ref: Expression of IGF-II and IGF-binding proteins by colon cancer cells in relation to growth response to IGFs.
PMID: 7524348
 Ref: Mapping of a target region of allelic loss to a 0.5-cM interval on chromosome 22q13 in human colorectal cancer.
PMID: 10500065
 Ref: Induction of apoptosis in human gastric cancer by sodium butyrate.
PMID: 10810354
 Ref: p53 upregulates cFLIP, inhibits transcription of NF-kappaB-regulated genes and induces caspase-8-independent cell death in DLD-1 cells.
PMID: 11313989
 Ref: Identification of a novel SP3 binding site in the promoter of human IGFBP4 gene: role of SP3 and AP-1 in regulating promoter activity in CaCo2 cells.
PMID: 14767471
Ref: Expression patterns of cell cycle and apoptosis-related genes in a multidrug-resistant human colon carcinoma cell line.
PMID: 15180185
Ref: Dysregulation of apoptosis is a major mechanism in the lymph node involvement in colorectal carcinoma.
PMID: 15254690
 Ref: The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim.
PMID: 15767553
Ref: Bcl-XL small interfering RNA suppresses the proliferation of 5-fluorouracil-resistant human colon cancer cells.
PMID: 15767554
Ref: Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors.
PMID: 15824729
Ref: Proteasome inhibitors-mediated TRAIL resensitization and Bik accumulation.
PMID: 16082182
Ref: Cancer-specific gene therapy.
PMID: 16096014
 Ref: Mutant Bik gene transferred by cationic liposome inhibits peritoneal disseminated murine colon cancer.
PMID: 17636408
 Ref: Focused PCR screen reveals p53 dependence of nitric oxide-induced apoptosis and up-regulation of maspin and plasminogen activator inhibitor-1 in tumor cells.
PMID: 19147537
 Ref: An ARF/CtBP2 complex regulates BH3-only gene expression and p53-independent apoptosis.
PMID: 19798104
Ref: Therapeutic targeting of C-terminal binding protein in human cancer.
PMID: 20930544
 Ref: Small interfering RNA targeting mcl-1 enhances proteasome inhibitor-induced apoptosis in various solid malignant tumors.
PMID: 22078414
 Ref: Decitabine and vorinostat cooperate to sensitize colon carcinoma cells to Fas ligand-induced apoptosis in vitro and tumor suppression in vivo.
PMID: 22461695
Ref: Exosome-related multi-pass transmembrane protein TSAP6 is a target of rhomboid protease RHBDD1-induced proteolysis.
PMID: 22624035
 Ref: Different susceptibility of colon cancer DLD-1 and LOVO cell lines to apoptosis induced by DMU-212, a synthetic resveratrol analogue.
PMID: 24055891
 Ref: Mechanisms underlying apoptosis-inducing effects of Kaempferol in HT-29 human colon cancer cells.
PMID: 24549175
 Ref: Reversal of Mutant KRAS-Mediated Apoptosis Resistance by Concurrent Noxa/Bik Induction and Bcl-2/Bcl-xL Antagonism in Colon Cancer Cells.
PMID: 25548100
Ref: The Mutant KRAS Gene Up-regulates BCL-XL Protein via STAT3 to Confer Apoptosis Resistance That Is Reversed by BIM Protein Induction and BCL-XL Antagonism.
PMID: 26245900
 Ref: Inhibition of HSP90 by AUY922 Preferentially Kills Mutant KRAS Colon Cancer Cells by Activating Bim through ER Stress.
PMID: 26832792
Ref: Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition.
PMID: 27634879
 Ref: A novel oncolytic adenovirus based on simian adenovirus serotype 24.
PMID: 28460470
Ref: Electrochemical peptide sensor for diagnosing adenoma-carcinoma transition in colon cancer.
PMID: 28697446
Ref: Biphasic ROS production, p53 and BIK dictate the mode of cell death in response to DNA damage in colon cancer cells.
PMID: 28796811
Ref: Probiotic Strain Lactobacillus casei BL23 Prevents Colitis-Associated Colorectal Cancer.
PMID: 29209314