Primary Site >> Colorectal Cancer

Gene >> BCL9L

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Ref: BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling.
PMID: 17113272
Ref: The function of BCL9 in Wnt/beta-catenin signaling and colorectal cancer cells.
PMID: 18627596
Ref: A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
PMID: 19328798
Ref: BCL9-2 promotes early stages of intestinal tumor progression.
PMID: 21703997
Ref: LEF1 and B9L shield beta-catenin from inactivation by Axin, desensitizing colorectal cancer cells to tankyrase inhibitors.
PMID: 24419084
Ref: Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.
PMID: 24755471
Ref: Plumbagin downregulates Wnt signaling independent of p53 in human colorectal cancer cells.
PMID: 24828199
Ref: MiR-29b downregulates canonical Wnt signaling by suppressing coactivators of beta-catenin in human colorectal cancer cells.
PMID: 24913975
Ref: Single-walled carbon nanotubes functionalized with aptamer and piperazine-polyethylenimine derivative for targeted siRNA delivery into breast cancer cells.
PMID: 25712164
Ref: Genome-wide mutation profiles of colorectal tumors and associated liver metastases at the exome and transcriptome levels.
PMID: 26109429
Ref: Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma.
PMID: 27149842
Ref: The role of Pygo2 for Wnt/ss-catenin signaling activity during intestinal tumor initiation and progression.
PMID: 27811361
Ref: BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer.
PMID: 28073006
Ref: Lack of APC somatic mutation is associated with early-onset colorectal cancer in African Americans.
PMID: 30239619