Primary Site >> Stomach Cancer
Gene >> BCL2L1
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Ref: Immunohistochemical analysis of Bcl-2 family proteins in adenocarcinomas of the stomach. PMID: 8909234 Ref: Over-expression of bcl-xL gene in human gastric adenomas and carcinomas. PMID: 8980174 |
Ref: Effects of transcription and translation inhibitors on a human gastric carcinoma cell line. Potential role of Bcl-X(S) in apoptosis triggered by these inhibitors. PMID: 9174110 Ref: Dexamethasone suppresses apoptosis in a human gastric cancer cell line through modulation of bcl-x gene expression. PMID: 9326359 |
Ref: Modulation of apoptosis by endogenous Bcl-xL expression in MKN-45 human gastric cancer cells. PMID: 9840921 |
Ref: Low rate of apoptosis and overexpression of bcl-2 in Epstein-Barr virus-associated gastric carcinoma. PMID: 10383694 Ref: Inhibition of gastric cancer by camptothecin involves apoptosis and multiple cellular pathways. PMID: 10455888 |
Ref: Direct growth suppressive activity of interferon-alpha and -gamma on human gastric cancer cells. PMID: 11064392 |
Ref: Diffuse and intestinal type gastric carcinomas differ in their expression of apoptosis related proteins. PMID: 12944556 |
Ref: Distinct role and functional mode of TR3 and RARalpha in mediating ATRA-induced signalling pathway in breast and gastric cancer cells. PMID: 14592536 Ref: Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45. PMID: 14605879 Ref: Expression of thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase, E2F-1, Bak, Bcl-X, and Bcl-2, and clinical outcomes for gastric cancer patients treated with bolus 5-fluorouracil. PMID: 14654896 Ref: Effect of peroxisome proliferator activated receptor gamma ligands on growth and gene expression profiles of gastric cancer cells. PMID: 14960510 Ref: Expression of nuclear factor-kappa B and target genes in gastric precancerous lesions and adenocarcinoma: association with Helicobactor pylori cagA (+) infection. PMID: 14966904 Ref: Expression of COX-2, mPGE-synthase1, MDR-1 (P-gp), and Bcl-xL: a molecular pathway of H pylori-related gastric carcinogenesis. PMID: 14991895 Ref: Rho/Rhotekin-mediated NF-kappaB activation confers resistance to apoptosis. PMID: 15480428 Ref: Inhibitory effects of mifepristone on the growth of human gastric cancer cell line MKN-45 in vitro and in vivo. PMID: 15669177 |
Ref: REG Ialpha protein may function as a trophic and/or anti-apoptotic factor in the development of gastric cancer. PMID: 15765400 Ref: Silencing of Bcl-XL expression in human MGC-803 gastric cancer cells by siRNA. PMID: 16077903 |
Ref: Hydrogen peroxide-induced apoptosis in human gastric carcinoma MGC803 cells. PMID: 16533611 Ref: Immunohistochemical detection of apoptotic markers in gastric cancer. PMID: 16555550 Ref: CoCl2-induced HIF-1alpha expression correlates with proliferation and apoptosis in MKN-1 cells: a possible role for the PI3K/Akt pathway. PMID: 16865270 Ref: Differential expression of apoptosis related proteins and nitric oxide synthases in Epstein Barr associated gastric carcinomas. PMID: 16937490 Ref: Resveratrol engages selective apoptotic signals in gastric adenocarcinoma cells. PMID: 17007014 |
Ref: KLF4 suppresses transformation of pre-B cells by ABL oncogenes. PMID: 16954505 Ref: Helicobacter pylori-induced apoptosis in T cells is mediated by the mitochondrial pathway independent of death receptors. PMID: 17217377 Ref: Apoptotic effect of Epigallocatechin-3-gallate on the human gastric cancer cell line MKN45 via activation of the mitochondrial pathway. PMID: 17696257 Ref: Docetaxel: in gastric cancer. PMID: 17722957 |
Ref: REG Ialpha protein mediates an anti-apoptotic effect of STAT3 signaling in gastric cancer cells. PMID: 18024479 |
Ref: Reduction of TIP30 correlates with poor prognosis of gastric cancer patients and its restoration drastically inhibits tumor growth and metastasis. PMID: 18972434 Ref: Reg IV enhances peritoneal metastasis in gastric carcinomas. PMID: 19143768 Ref: [Study on apoptosis of human stomach SGC-7901 cells induced by extracts of Solanum lyratum]. PMID: 19504972 Ref: Arginine deiminase originating from Lactococcus lactis ssp. lactis American Type Culture Collection (ATCC) 7962 induces G1-phase cell-cycle arrest and apoptosis in SNU-1 stomach adenocarcinoma cells. PMID: 19624867 Ref: A novel histone deacetylase inhibitor, CG0006, induces cell death through both extrinsic and intrinsic apoptotic pathways. PMID: 19644355 |
Ref: Eugenol induces apoptosis and inhibits invasion and angiogenesis in a rat model of gastric carcinogenesis induced by MNNG. PMID: 20434464 Ref: The C-terminal flanking peptide (CTFP) of progastrin inhibits apoptosis via a PI3-kinase-dependent pathway. PMID: 20727916 Ref: The intrinsic apoptotic signaling pathway in gastric adenocarcinomas of Brazilian patients: Immunoexpression of the Bcl-2 family (Bcl-2, Bcl-x, Bak, Bax, Bad) determined by tissue microarray analysis. PMID: 21472231 Ref: Role of REG Ialpha in gastric carcinogenesis: Gastrin-associated proliferative and anti-apoptotic activities. PMID: 21472346 |
Ref: Coleusin factor exerts cytotoxic activity by inducing G0/G1 cell cycle arrest and apoptosis in human gastric cancer BGC-823 cells. PMID: 21093146 Ref: Sox17 regulates proliferation and cell cycle during gastric cancer progression. PMID: 21514720 Ref: Antiproliferative activity of fucoidan was associated with the induction of apoptosis and autophagy in AGS human gastric cancer cells. PMID: 21535865 Ref: Curcumin reverses chemoresistance of human gastric cancer cells by downregulating the NF-kappaB transcription factor. PMID: 21811763 |
Ref: Identification of protein expression signatures in gastric carcinomas using clustering analysis. PMID: 21777278 Ref: Elevated fibroblast growth factor-inducible 14 expression promotes gastric cancer growth via nuclear factor-kappaB and is associated with poor patient outcome. PMID: 21993017 Ref: Paeoniflorin modulates multidrug resistance of a human gastric cancer cell line via the inhibition of NF-kappaB activation. PMID: 22051979 Ref: Targeting of colorectal cancer growth, metastasis, and anti-apoptosis in BALB/c nude mice via APRIL siRNA. PMID: 22170570 Ref: Inhibition of STAT3 signaling pathway by nitidine chloride suppressed the angiogenesis and growth of human gastric cancer. PMID: 22203730 Ref: Plumbagin inhibits cell growth and potentiates apoptosis in human gastric cancer cells in vitro through the NF-kappaB signaling pathway. PMID: 22231395 Ref: Low expression of Beclin 1, associated with high Bcl-xL, predicts a malignant phenotype and poor prognosis of gastric cancer. PMID: 22240664 Ref: MiR-135a targets JAK2 and inhibits gastric cancer cell proliferation. PMID: 22310976 Ref: First evidence that gamma-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-kappaB pathway. PMID: 22351692 Ref: 15-PGDH is reduced and induces apoptosis and cell cycle arrest in gastric carcinoma. PMID: 22416177 Ref: Immunohistochemical assessment of apoptosis-associated proteins: p53, Bcl-xL, Bax and Bak in gastric cancer cells in correlation with clinical and pathomorphological factors. PMID: 22440942 Ref: MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors. PMID: 22456335 Ref: Resistance to TRAIL is mediated by DARPP-32 in gastric cancer. PMID: 22589394 Ref: Down-regulation of AP-4 inhibits proliferation, induces cell cycle arrest and promotes apoptosis in human gastric cancer cells. PMID: 22615908 Ref: Pyruvate kinase M2 promotes the growth of gastric cancer cells via regulation of Bcl-xL expression at transcriptional level. PMID: 22627140 Ref: Dracorhodin perchlorate inhibits PI3K/Akt and NF-kappaB activation, up-regulates the expression of p53, and enhances apoptosis. PMID: 22711363 Ref: MDR1-P-glycoprotein behaves as an oncofetal protein that promotes cell survival in gastric cancer cells. PMID: 22751348 Ref: Rhein induces apoptosis of human gastric cancer SGC-7901 cells via an intrinsic mitochondrial pathway. PMID: 22850871 Ref: Vitamin C induces apoptosis in AGS cells by down-regulation of 14-3-3sigma via a mitochondrial dependent pathway. PMID: 22953941 Ref: Dapper homolog 1 is a novel tumor suppressor in gastric cancer through inhibiting the nuclear factor-kappaB signaling pathway. PMID: 23073659 |
Ref: Cytotoxicity of dioscin in human gastric carcinoma cells through death receptor and mitochondrial pathways. PMID: 22334414 Ref: MicroRNA-18a modulates STAT3 activity through negative regulation of PIAS3 during gastric adenocarcinogenesis. PMID: 23322197 Ref: Hyaluronic acid receptor-targetable imidazolized nanovectors for induction of gastric cancer cell death by RNA interference. PMID: 23478035 Ref: A biodegradable polymersome containing Bcl-xL siRNA and doxorubicin as a dual delivery vehicle for a synergistic anticancer effect. PMID: 23613425 Ref: IL-26 promotes the proliferation and survival of human gastric cancer cells by regulating the balance of STAT1 and STAT3 activation. PMID: 23704922 Ref: Somatostatin receptor 1, a novel EBV-associated CpG hypermethylated gene, contributes to the pathogenesis of EBV-associated gastric cancer. PMID: 23722468 Ref: Cancer stem cells biomarkers in gastric carcinogenesis. PMID: 23949555 Ref: Raddeanin A induces human gastric cancer cells apoptosis and inhibits their invasion in vitro. PMID: 23988447 Ref: Tetrandrine induces mitochondria-mediated apoptosis in human gastric cancer BGC-823 cells. PMID: 24098511 Ref: Combination of the FGFR4 inhibitor PD173074 and 5-fluorouracil reduces proliferation and promotes apoptosis in gastric cancer. PMID: 24126887 |
Ref: Tamoxifen reduces P-gp-mediated multidrug resistance via inhibiting the PI3K/Akt signaling pathway in ER-negative human gastric cancer cells. PMID: 24184201 Ref: Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products. PMID: 24233024 Ref: STAT3 activation in tumor cell-free lymph nodes predicts a poor prognosis for gastric cancer. PMID: 24696730 Ref: Flavonoids identified from Korean Scutellaria baicalensis induce apoptosis by ROS generation and caspase activation on human fibrosarcoma cells. PMID: 24707875 Ref: Transduction motif analysis of gastric cancer based on a human signaling network. PMID: 24838641 Ref: The direct effect of estrogen on cell viability and apoptosis in human gastric cancer cells. PMID: 24934239 Ref: Silibinin inhibits proliferation, induces apoptosis and causes cell cycle arrest in human gastric cancer MGC803 cells via STAT3 pathway inhibition. PMID: 25169527 Ref: Tanshinone IIA inhibits human gastric carcinoma AGS cell growth by decreasing BiP, TCTP, Mcl1 and BclxL and increasing Bax and CHOP protein expression. PMID: 25270224 Ref: 13-acetoxysarcocrassolide induces apoptosis on human gastric carcinoma cells through mitochondria-related apoptotic pathways: p38/JNK activation and PI3K/AKT suppression. PMID: 25342459 |
Ref: MnSOD overexpression confers cisplatin resistance in lung adenocarcinoma via the NF-kappaB/Snail/Bcl-2 pathway. PMID: 25499851 Ref: Antitumorigenic effect of plumbagin by induction of SH2-containing protein tyrosine phosphatase 1 in human gastric cancer cells. PMID: 25815436 Ref: Naringin induces autophagy-mediated growth inhibition by downregulating the PI3K/Akt/mTOR cascade via activation of MAPK pathways in AGS cancer cells. PMID: 26201693 Ref: Identification of miRNomes in human stomach and gastric carcinoma reveals miR-133b/a-3p as therapeutic target for gastric cancer. PMID: 26276722 Ref: Poncirin Induces Apoptosis in AGS Human Gastric Cancer Cells through Extrinsic Apoptotic Pathway by up-Regulation of Fas Ligand. PMID: 26393583 Ref: Genomic alterations in BCL2L1 and DLC1 contribute to drug sensitivity in gastric cancer. PMID: 26401016 Ref: beta-Asarone inhibits gastric cancer cell proliferation. PMID: 26502896 Ref: LDOC1 inhibits proliferation and promotes apoptosis by repressing NF-kappaB activation in papillary thyroid carcinoma. PMID: 26637328 |
Ref: Anticancer effect of 2,7-dihydroxy-3-methylanthraquinone on human gastric cancer SGC-7901 cells in vitro and in vivo. PMID: 25853970 Ref: Silencing of FGFR4 could influence the biological features of gastric cancer cells and its therapeutic value in gastric cancer. PMID: 26432329 Ref: The dual induction of apoptosis and autophagy by SZC014, a synthetic oleanolic acid derivative, in gastric cancer cells via NF-kappaB pathway. PMID: 26547583 Ref: The over-expression of FGFR4 could influence the features of gastric cancer cells and inhibit the efficacy of PD173074 and 5-fluorouracil towards gastric cancer. PMID: 26662569 Ref: Apoptotic Cell Death Induced by ofLBP6A, Lipopolysaccharide Binding Protein Model Peptide, Derived from Paralichthy olivaceus on MKN-28 Cells. PMID: 27009854 Ref: Grifola frondosa Glycoprotein GFG-3a Arrests S phase, Alters Proteome, and Induces Apoptosis in Human Gastric Cancer Cells. PMID: 27040446 Ref: Salinomycin exerts anti-angiogenic and anti-tumorigenic activities by inhibiting vascular endothelial growth factor receptor 2-mediated angiogenesis. PMID: 27058891 Ref: The natural secolignan peperomin E induces apoptosis of human gastric carcinoma cells via the mitochondrial and PI3K/Akt signaling pathways in vitro and in vivo. PMID: 27288917 Ref: Sinularin Induces Apoptosis through Mitochondria Dysfunction and Inactivation of the pI3K/Akt/mTOR Pathway in Gastric Carcinoma Cells. PMID: 27472346 Ref: A new brominated chalcone derivative suppresses the growth of gastric cancer cells in vitro and in vivo involving ROS mediated up-regulation of DR5 and 4 expression and apoptosis. PMID: 27594528 Ref: Trefoil factor family 2 expression inhibits gastric cancer cell growth and invasion in vitro via interactions with the transcription factor Sp3. PMID: 27668303 Ref: Berberine inhibits EGFR signaling and enhances the antitumor effects of EGFR inhibitors in gastric cancer. PMID: 27738318 Ref: iTRAQ-Based Proteomic Analysis of Ginsenoside F2 on Human Gastric Carcinoma Cells SGC7901. PMID: 27829861 |
Ref: Prospero homeobox 1 mediates the progression of gastric cancer by inducing tumor cell proliferation and lymphangiogenesis. PMID: 26759228 Ref: Polyethylenimine-functionalized carbon nanotubes tagged with AS1411 aptamer for combination gene and drug delivery into human gastric cancer cells. PMID: 27840158 Ref: 7-O-Geranylquercetin induces apoptosis in gastric cancer cells via ROS-MAPK mediated mitochondrial signaling pathway activation. PMID: 28076833 Ref: Luteolin selectively kills STAT3 highly activated gastric cancer cells through enhancing the binding of STAT3 to SHP-1. PMID: 28182003 Ref: Inhibition of polypyrimidine tract-binding protein 3 induces apoptosis and cell cycle arrest, and enhances the cytotoxicity of 5- fluorouracil in gastric cancer cells. PMID: 28222070 Ref: MicroRNA-20b suppresses the expression of ZFP-148 in viral myocarditis. PMID: 28247213 Ref: Knockdown of ZFPL1 results in increased autophagy and autophagyrelated cell death in NCIN87 and BGC823 human gastric carcinoma cell lines. PMID: 28447717 Ref: Anticancer efficacy of the ethyl acetate extract from the traditional Chinese medicine herb Celastrus orbiculatus against human gastric cancer. PMID: 28476678 Ref: Bcl-2 and Bcl-xL mediate resistance to receptor tyrosine kinase-targeted therapy in lung and gastric cancer. PMID: 28885267 Ref: GRAM domain-containing protein 1B (GRAMD1B), a novel component of the JAK/STAT signaling pathway, functions in gastric carcinogenesis. PMID: 29383166 |
Ref: Lanatoside C inhibits cell proliferation and induces apoptosis through attenuating Wnt/beta-catenin/c-Myc signaling pathway in human gastric cancer cell. PMID: 29475060 Ref: Melatonin induces the apoptosis and inhibits the proliferation of human gastric cancer cells via blockade of the AKT/MDM2 pathway. PMID: 29484412 Ref: Multi-omics analysis identifies pathways and genes involved in diffuse-type gastric carcinogenesis induced by E-cadherin, p53, and Smad4 loss in mice. PMID: 29528141 Ref: The proto-oncogene Mer tyrosine kinase is a novel therapeutic target in mantle cell lymphoma. PMID: 29554921 Ref: 7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2alpha/ATF4/CHOP Signaling Pathway. PMID: 29587440 Ref: MAPK/c-Jun signaling pathway contributes to the upregulation of the anti-apoptotic proteins Bcl-2 and Bcl-xL induced by Epstein-Barr virus-encoded BARF1 in gastric carcinoma cells. PMID: 29725459 Ref: High Expression of ABL2 Suppresses Apoptosis in Gastric Cancer. PMID: 29767389 Ref: Mancozeb selectively induces mitochondrial-mediated apoptosis in human gastric carcinoma cells through ROS generation. PMID: 29902665 Ref: The effect of HIF-1alpha and PKM1 expression on acquisition of chemoresistance. PMID: 30013393 Ref: Targeting of the C-Jun/BCL-XL/P21 Axis Accelerates the Switch from Senescence to Apoptosis Upon ROC1 Knockdown in Gastric Cancer Cells. PMID: 30041196 Ref: Xanthohumol induces apoptosis via caspase activation, regulation of Bcl-2, and inhibition of PI3K/Akt/mTOR-kinase in human gastric cancer cells. PMID: 30119200 Ref: Quercetin induced cell apoptosis and altered gene expression in AGS human gastric cancer cells. PMID: 30152185 Ref: TRIM59 overexpression correlates with poor prognosis and contributes to breast cancer progression through AKT signaling pathway. PMID: 30175868 Ref: Induction of apoptosis and G1 phase cell cycle arrest by Aster incisus in AGS gastric adenocarcinoma cells. PMID: 30226597 Ref: Induction of ER Stress-Mediated Apoptosis by the Major Component 5,7,4'-Trimethoxyflavone Isolated from Kaempferia parviflora Tea Infusion. PMID: 30273054 Ref: TCF21 inhibits proliferation and chemoresistance through the AKT pathway in human gastric cancer. PMID: 30296564 Ref: Carnosol suppresses patient-derived gastric tumor growth by targeting RSK2. PMID: 30344937 |