Primary Site >> Esophagus Cancer
Gene >> BCL2
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Ref: bcl-2 expression and prognosis in squamous-cell carcinomas of the esophagus. PMID: 8797876 |
Ref: Expression of bcl-2 protein in esophageal squamous cell carcinomas and its association with lymph node metastasis. PMID: 9083148 Ref: Apoptosis is inhibited early in the dysplasia-carcinoma sequence of Barrett esophagus. PMID: 9230856 Ref: Immunohistochemical expression of bcl-2 protein in squamous cell carcinoma and basaloid carcinoma of the esophagus. PMID: 9306579 Ref: Expression of Bax, a pro-apoptotic member of the Bcl-2 family, in esophageal squamous cell carcinoma. PMID: 9389564 |
Ref: Expression of Bcl-X(L), an antiapoptotic member of the Bcl-2 family, in esophageal squamous cell carcinoma. PMID: 9533524 Ref: [A case report of esophageal carcinoma with grade 3 response by preoperative chemotherapy using CDDP/5-FU/LV]. PMID: 9617331 Ref: Alpha-difluoromethylornithine inhibits N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in zinc-deficient rats: effects on esophageal cell proliferation and apoptosis. PMID: 9850069 Ref: Expression of apoptosis-regulating proteins and outcome of esophageal cancer patients treated by combined therapy modalities. PMID: 9865911 Ref: Apoptosis and its relationship with cell proliferation, p53, Waf1p21, bcl-2 and c-myc in esophageal carcinogenesis studied with a high-risk population in northern China. PMID: 11819301 |
Ref: Usefulness of p53 protein, Bcl-2 protein and Ki-67 as predictors of chemosensitivity of malignant tumors. PMID: 10203614 Ref: Immunohistochemical analysis for cell proliferation-related protein expression in small cell carcinoma of the esophagus; a comparative study with small cell carcinoma of the lung and squamous cell carcinoma of the esophagus. PMID: 10212809 Ref: Analysis of Ki-67, p53 and Bcl-2 expression in the dysplasia-carcinoma sequence of Barrett's esophagus. PMID: 10373674 Ref: [Histological and molecular prognostic factors in esophageal cancer]. PMID: 10714193 Ref: [In vitro and in vivo studies on the biologic effects and molecular mechanism of recombinant RA538 and antisense C-myc adenovirus on human gastric, esophageal and cancer cell lines with high-expression of Bcl-2 gene]. PMID: 12532785 |
Ref: Modern pathology: prognostic parameters in squamous cell carcinoma of the esophagus. PMID: 10693235 Ref: Caspase activation and changes in Bcl-2 family member protein expression associated with E2F-1-mediated apoptosis in human esophageal cancer cells. PMID: 10778992 Ref: Aspirin induction of apoptosis in esophageal cancer: a potential for chemoprevention. PMID: 10868686 Ref: Altered mechanisms of apoptosis in colon cancer: Fas resistance and counterattack in the tumor-immune conflict. PMID: 10911913 Ref: Expression of p53, bcl-2, and bax as predictors of response to radiotherapy in esophageal cancer. PMID: 11206630 Ref: [Morphological changes of mitochondria in apoptosis of esophageal carcinoma cells induced by As(2)O(3)]. PMID: 11866913 |
Ref: Hypoxia inducible factor (HIF-1a and HIF-2a) expression in early esophageal cancer and response to photodynamic therapy and radiotherapy. PMID: 11280732 Ref: Clinical and experimental evidence of Bcl-2 involvement in the response to photodynamic therapy. PMID: 11299823 Ref: Genistein, a tyrosine kinase inhibitor, enhanced radiosensitivity in human esophageal cancer cell lines in vitro: possible involvement of inhibition of survival signal transduction pathways. PMID: 11316564 Ref: Induction of apoptosis by cyclo-oxygenase-2 inhibitor NS398 through a cytochrome C-dependent pathway in esophageal cancer cells. PMID: 11410869 Ref: Metastatic adenocarcinoma of the esophagus to the skin: new patterns of tumor recurrence and alternate treatments for palliation. PMID: 11493381 Ref: An immunohistochemical examination of basaloid squamous cell carcinoma of the esophagus: report of a case. PMID: 11495163 Ref: Expression of nitrotyrosine is associated with angiogenesis in esophageal squamous cell carcinoma. PMID: 11848490 |
Ref: Apoptotic and proliferative indexes in esophageal cancer: predictors of response to neoadjuvant therapy [corrected]. PMID: 12559188 Ref: Resveratrol induces apoptosis in human esophageal carcinoma cells. PMID: 12632486 Ref: Interleukin-6 acts as an antiapoptotic factor in human esophageal carcinoma cells through the activation of both STAT3 and mitogen-activated protein kinase pathways. PMID: 14586407 Ref: [Cyclooxygenase-2 expression in esophageal cancer cells and induction by mitomycin C]. PMID: 14633464 Ref: Epidermal growth factor receptor, p53 mutation, and pathological response predict survival in patients with locally advanced esophageal cancer treated with preoperative chemoradiotherapy. PMID: 14695149 Ref: Apoptotic and proliferative indexes in esophageal cancer: Predictors of response to neoadjuvant therapy apoptosis and proliferation in esophageal cancer. PMID: 29340962 |
Ref: The multistage process of carcinogenesis in human esophageal epithelial cells induced by human papillomavirus. PMID: 14767516 Ref: Recent results in understanding molecular pathways in the medical treatment of esophageal and gastric cancer. PMID: 15007244 Ref: Molecular biology of esophageal cancer. PMID: 15138356 Ref: Flavopiridol as a radio-sensitizer for esophageal cancer cell lines. PMID: 15569374 Ref: [Toxicity of arsenic trioxide to human lung adenocarcinoma cell line SPCA1 and its mechanism]. PMID: 15601551 |
Ref: The cytostatic and cytotoxic effects of oridonin (Rubescenin), a diterpenoid from Rabdosia rubescens, on tumor cells of different lineage. PMID: 15703811 Ref: Immunohistochemistry of p53, Bcl-2, and Ki-67 as predictors of chemosensitivity. PMID: 15901938 Ref: Bax/Bcl-2 expression levels of 2-methoxyestradiol-exposed esophageal cancer cells. PMID: 16011306 Ref: Bile salts inhibit growth and induce apoptosis of human esophageal cancer cell line. PMID: 16127738 Ref: Dual effects of 8-Br-cAMP on differentiation and apoptosis of human esophageal cancer cell line Eca-109. PMID: 16425431 |
Ref: Id-1 promotes proliferation of p53-deficient esophageal cancer cells. PMID: 16506209 Ref: Enhancement of Apo2L/TRAIL-mediated cytotoxicity in esophageal cancer cells by cisplatin. PMID: 17172403 |
Ref: Anticancer effects of gallic acid isolated from Indonesian herbal medicine, Phaleria macrocarpa (Scheff.) Boerl, on human cancer cell lines. PMID: 17273761 Ref: Involvement of IFN regulatory factor (IRF)-1 and IRF-2 in the formation and progression of human esophageal cancers. PMID: 17363571 Ref: The flavonoid component isorhamnetin in vitro inhibits proliferation and induces apoptosis in Eca-109 cells. PMID: 17368593 Ref: [Effects and mechanism of lutein on apoptosis of esophageal carcinoma EC9706 cells]. PMID: 17455471 Ref: Role of BCL2 (ala43thr), CCND1 (G870A) and FAS (A-670G) polymorphisms in modulating the risk of developing esophageal cancer. PMID: 17561354 Ref: Bax upregulation may provide a rationale for the low incidence of esophageal adenocarcinoma in a Greek cohort of patients with Barrett's esophagus. PMID: 17591046 Ref: Influence of apoptosis (BCL2, FAS), cell cycle (CCND1) and growth factor (EGF, EGFR) genetic polymorphisms on survival outcome: an exploratory study in squamous cell esophageal cancer. PMID: 17912028 Ref: [Apoptosis in esophageal cancer cells induced by all-trans retinoic acid]. PMID: 18396638 |
Ref: Interplay between oncoproteins and antioxidant enzymes in esophageal carcinoma treated without and with chemoradiotherapy: a prospective study. PMID: 18207033 Ref: Adjuvant chemotherapy of cisplatin, 5-fluorouracil and leucovorin for complete resectable esophageal cancer: a case-matched cohort study in east China. PMID: 18430100 Ref: Synergistic apoptotic effects of taurolidine and TRAIL on squamous carcinoma cells of the esophagus. PMID: 18497982 Ref: Antiproliferation and apoptosis induction of paeonol in human esophageal cancer cell lines. PMID: 18522637 Ref: Effects of Oxymatrine on the apoptosis of human esophageal carcinoma Eca109 cell line and its mechanism. PMID: 18563331 Ref: Correlation between loss of Bcl-XL expression and improved prognosis in advanced esophageal cancer treated by preoperative chemoradiotherapy. PMID: 18580065 |
Ref: Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis. PMID: 19073162 Ref: Targets for molecular therapy in esophageal squamous cell carcinoma: an immunohistochemical analysis. PMID: 19302210 Ref: Biomarkers of apoptosis and survival in esophageal squamous cell carcinoma. PMID: 19728877 Ref: Mantle cell lymphoma-like solitary polypoid tumor of the esophagus: a case report. PMID: 19829839 Ref: Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation. PMID: 19860666 Ref: Inhibition of BCL2 expression and activity increases H460 sensitivity to the growth inhibitory effects of polyphenon E. PMID: 20192119 |
Ref: A phase I trial of oblimersen sodium in combination with cisplatin and 5-fluorouracil in patients with advanced esophageal, gastroesophageal junction, and gastric carcinoma. PMID: 19738454 Ref: Down-regulation of miR-27a might reverse multidrug resistance of esophageal squamous cell carcinoma. PMID: 19960259 Ref: CHAP31 induces apoptosis only via the intrinsic pathway in human esophageal cancer cells. PMID: 20215787 Ref: The prognostic and chemotherapeutic value of miR-296 in esophageal squamous cell carcinoma. PMID: 20485139 Ref: Cyclooxygenase-2 inhibitor NS398 enhances radiosensitivity of radioresistant esophageal cancer cells by inhibiting AKT activation and inducing apoptosis. PMID: 20486853 Ref: Expression of Bmi-1 gene in esophageal carcinoma cell EC9706 and its effect on cell cycle, apoptosis and migration. PMID: 20591222 Ref: [Effect of gecko alcohol extract on human esophageal squamous carcinoma cell line EC9706 and anti-tumor activity in vivo]. PMID: 21046756 |
Ref: {2-[(3-Carboxy-1-oxopropyl) amino]-2-deoxy-D-Glucose} suppresses proliferation and induces apoptosis in the human esophageal cancer cell line. PMID: 20524085 Ref: Effect and mechanism of 5-aminolevulinic acid-mediated photodynamic therapy in esophageal cancer. PMID: 20676910 Ref: Slug regulates proliferation and invasiveness of esophageal adenocarcinoma cells in vitro and in vivo. PMID: 20730573 Ref: Inhibition of hypoxia inducible factor 1alpha expression suppresses the progression of esophageal squamous cell carcinoma. PMID: 21519196 Ref: Correlation between tumor-associated proteins and response to neoadjuvant treatment in patients with advanced squamous-cell esophageal cancer. PMID: 21617238 Ref: [Apoptosis and growth arrest of human esophageal squamous cell carcinoma cell EC9706 induced by Fufangkushen injection]. PMID: 22322065 |
Ref: The -938A/A genotype of BCL2 gene is associated with esophageal cancer. PMID: 22187149 Ref: Curcumin induces cell death in esophageal cancer cells through modulating Notch signaling. PMID: 22363450 Ref: Paris polyphylla Smith extract induces apoptosis and activates cancer suppressor gene connexin26 expression. PMID: 22502669 Ref: Early evaluation of the apoptotic index ratio is useful in predicting the efficacy of chemoradiotherapy in esophageal squamous cell carcinoma. PMID: 22740896 Ref: Effect of altered WIG-1 expression on DDP sensitivity in a DDP-resistant esophageal squamous cancer cell line. PMID: 22794122 Ref: Antitumor activity of folate-targeted, paclitaxel-loaded polymeric micelles on a human esophageal EC9706 cancer cell line. PMID: 22848173 Ref: [Small interfering RNA in silencing cox-2 expression enhances radiosensitivity of esophageal cancer EC9706 cell]. PMID: 22944132 Ref: Expression of p14(ARF), p15(INK4b), p16(INK4a) and skp2 increases during esophageal squamous cell cancer progression. PMID: 22970012 Ref: Intervention effects of nedaplatin and cisplatin on proliferation and apoptosis of human tumour cells in vitro. PMID: 23167374 |
Ref: Effect of miR-451 on the biological behavior of the esophageal carcinoma cell line EC9706. PMID: 23053883 Ref: Growth inhibitory effects and molecular mechanisms of crotoxin treatment in esophageal Eca-109 cells and transplanted tumors in nude mice. PMID: 23202800 Ref: The variability of oxLDL-induced cytotoxicity on different types of cell lines. PMID: 23479334 Ref: Epstein-Barr virus associated lymphoepithelial carcinoma of the esophagus. PMID: 23573354 Ref: Initiation of apoptosis, cell cycle arrest and autophagy of esophageal cancer cells by dihydroartemisinin. PMID: 23582790 Ref: OSU-03012, a non-Cox inhibiting celecoxib derivative, induces apoptosis of human esophageal carcinoma cells through a p53/Bax/cytochrome c/caspase-9-dependent pathway. PMID: 23652278 Ref: [Effects of deguelin on the proliferation and apoptosis of human esophageal cancer cell Ec-109: an experimental research]. PMID: 23713258 Ref: Effects of CXCR4 gene silencing by lentivirus shRNA on proliferation of the EC9706 human esophageal carcinoma cell line. PMID: 23744460 Ref: Phaseoloideside E, a novel natural triterpenoid saponin identified from Entada phaseoloides, induces apoptosis in Ec-109 esophageal cancer cells through reactive oxygen species generation. PMID: 23782641 Ref: Small proline-rich repeat protein 3 enhances the sensitivity of esophageal cancer cells in response to DNA damage-induced apoptosis. PMID: 23820115 Ref: The radiation-sensitizing effect of flavopiridol in the esophageal cancer cell line Eca109. PMID: 23833659 Ref: Hugl-1 induces apoptosis in esophageal carcinoma cells both in vitro and in vivo. PMID: 23864775 Ref: Primary mucosa-associated lymphoid tissue lymphoma of the esophagus, manifesting as a submucosal tumor. PMID: 23981946 Ref: MiR-429 up-regulation induces apoptosis and suppresses invasion by targeting Bcl-2 and SP-1 in esophageal carcinoma. PMID: 23999873 Ref: Establishment and characterization of a paclitaxelresistant human esophageal carcinoma cell line. PMID: 24002547 Ref: Cooperative inhibitory effect of sinomenine combined with 5-fluorouracil on esophageal carcinoma. PMID: 24363520 |
Ref: Matrine inhibits proliferation and induces apoptosis via BID-mediated mitochondrial pathway in esophageal cancer cells. PMID: 24510386 Ref: Anti-tumor activity and relative mechanism of ethanolic extract of Marsdenia tenacissima (Asclepiadaceae) against human hematologic neoplasm in vitro and in vivo. PMID: 24583069 Ref: Expression of bcl-2 and p53 in induction of esophageal cancer cell apoptosis by ECRG2 in combination with cisplatin. PMID: 24606472 Ref: Overexpression of OLC1 promotes tumorigenesis of human esophageal squamous cell carcinoma. PMID: 24608342 Ref: The molecular mechanisms of Tanshinone IIA on the apoptosis and arrest of human esophageal carcinoma cells. PMID: 24829906 Ref: Dihydroartemisinin accentuates the anti-tumor effects of photodynamic therapy via inactivation of NF-kappaB in Eca109 and Ec9706 esophageal cancer cells. PMID: 24854841 Ref: BTG1 underexpression is an independent prognostic marker in esophageal squamous cell carcinoma. PMID: 24969561 Ref: [Effect of downregulation of Tiam1 by siRNA on esophageal squamous cell carcinoma EC9706 cells]. PMID: 24989909 Ref: Inhibition of mammalian target of rapamycin by rapamycin increases the radiosensitivity of esophageal carcinoma Eca109 cells. PMID: 25009644 Ref: DADS suppresses human esophageal xenograft tumors through RAF/MEK/ERK and mitochondria-dependent pathways. PMID: 25026173 Ref: Expression of BAG-1 is closely related to cell differentiation and TNM stage in esophageal cancer and its downregulation inhibits the proliferation and invasion of human esophageal carcinoma cells. PMID: 25069471 Ref: Activating transcription factor 4 mediates a multidrug resistance phenotype of esophageal squamous cell carcinoma cells through transactivation of STAT3 expression. PMID: 25130172 Ref: Human umbilical cord mesenchymal stem cells promote carcinoma growth and lymph node metastasis when co-injected with esophageal carcinoma cells in nude mice. PMID: 25298750 Ref: Myricetin enhance chemosensitivity of 5-fluorouracil on esophageal carcinoma in vitro and in vivo. PMID: 25788859 |
Ref: Ternary copper(II) complexes with amino acid chains and heterocyclic bases: DNA binding, cytotoxic and cell apoptosis induction properties. PMID: 25555321 Ref: The Antitumor Activity of the Novel Compound Jesridonin on Human Esophageal Carcinoma Cells. PMID: 26103161 Ref: Low Expression of the bcl2 Gene in Gastric Adenocarcinomas in Mazandaran Province of Iran. PMID: 26320497 Ref: Expression of TP53, BCL-2, and VEGFA Genes in Esophagus Carcinoma and its Biological Significance. PMID: 26439224 Ref: Molecular characterization of antitumor effects of the rhizome extract from Curcuma zedoaria on human esophageal carcinoma cells. PMID: 26498695 Ref: Compound Radix Sophorae Flavescentis exerts antitumor effects by inhibiting the proliferation and inducing the apoptosis of esophageal carcinoma TE-8 cells. PMID: 26622820 |
Ref: Andrographolide radiosensitizes human esophageal cancer cell line ECA109 to radiation in vitro. PMID: 25059546 Ref: Traditional Chinese medicine targeting apoptotic mechanisms for esophageal cancer therapy. PMID: 26707140 Ref: Icariin displays anticancer activity against human esophageal cancer cells via regulating endoplasmic reticulum stress-mediated apoptotic signaling. PMID: 26892033 Ref: Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression. PMID: 26936624 Ref: Costunolide Induces Apoptosis through Generation of ROS and Activation of P53 in Human Esophageal Cancer Eca-109 Cells. PMID: 27078502 Ref: Downregulation of Ubiquitin-conjugating Enzyme UBE2D3 Promotes Telomere Maintenance and Radioresistance of Eca-109 Human Esophageal Carcinoma Cells. PMID: 27326259 Ref: Upregulation of microRNA-98 increases radiosensitivity in esophageal squamous cell carcinoma. PMID: 27422937 Ref: Thioridazine Sensitizes Esophageal Carcinoma Cell Lines to Radiotherapy-Induced Apoptosis In Vitro and In Vivo. PMID: 27453171 Ref: beta-Carotene synergistically enhances the anti-tumor effect of 5-fluorouracil on esophageal squamous cell carcinoma in vivo and in vitro. PMID: 27586268 Ref: Reversal effect of ouabain on multidrug resistance in esophageal carcinoma EC109/CDDP cells by inhibiting the translocation of Wnt/beta-catenin into the nucleus. PMID: 27709549 Ref: [Knockdown of NEDD9 inhibits the proliferation, invasion and migration of esophageal carcinoma EC109 cells]. PMID: 27916098 |
Ref: Targeting the Bcl-2 family and P-glycoprotein reverses paclitaxel resistance in human esophageal carcinoma cell line. PMID: 28441715 Ref: miR-195 Regulates Proliferation and Apoptosis through Inhibiting the mTOR/p70s6k Signaling Pathway by Targeting HMGA2 in Esophageal Carcinoma Cells. PMID: 28487599 Ref: Azoxystrobin Induces Apoptosis of Human Esophageal Squamous Cell Carcinoma KYSE-150 Cells through Triggering of the Mitochondrial Pathway. PMID: 28567017 Ref: Endoplasmic reticulum stress could induce autophagy and apoptosis and enhance chemotherapy sensitivity in human esophageal cancer EC9706 cells by mediating PI3K/Akt/mTOR signaling pathway. PMID: 28631572 Ref: Sirtuin 6 plays an oncogenic role and induces cell autophagy in esophageal cancer cells. PMID: 28653878 Ref: ABT-263 induces G1/G0-phase arrest, apoptosis and autophagy in human esophageal cancer cells in vitro. PMID: 28713162 Ref: RACK1 promotes radiation resistance in esophageal cancer via regulating AKT pathway and Bcl-2 expression. PMID: 28760343 Ref: Cellular expression, in-vitro and in-vivo confirmation of GAEC1 oncogenic properties in colon cancer. PMID: 28764863 Ref: RNAi-mediated TCF-3 gene silencing inhibits proliferation of Eca-109 esophageal cancer cells by inducing apoptosis. PMID: 28864779 Ref: Antitumor activity of Lobaplatin against esophageal squamous cell carcinoma through caspase-dependent apoptosis and increasing the Bax/Bcl-2 ratio. PMID: 28865364 Ref: Epigallocatechin-3-gallate promotes apoptosis and reversal of multidrug resistance in esophageal cancer cells. PMID: 28964574 Ref: Synergistic anticancer effect of combined crocetin and cisplatin on KYSE-150 cells via p53/p21 pathway. PMID: 29093644 Ref: Selective anticancer activity of the novel steroidal dihydropyridine spirooxindoles against human esophageal EC109 cells. PMID: 29196102 Ref: Propafenone suppresses esophageal cancer proliferation through inducing mitochondrial dysfunction. PMID: 29218248 |
Ref: Thymoquinone Augments Cisplatin-Induced Apoptosis on Esophageal Carcinoma Through Mitigating the Activation of JAK2/STAT3 Pathway. PMID: 29197940 Ref: RACKI induces chemotherapy resistance in esophageal carcinoma by upregulating the PI3K/AKT pathway and Bcl-2 expression. PMID: 29379302 Ref: [Corrigendum] miRNA-1207-5p is associated with cancer progression by targeting stomatin-like protein 2 in esophageal carcinoma. PMID: 29393389 Ref: Potent hydrazone derivatives targeting esophageal cancer cells. PMID: 29475156 Ref: Chinese herb medicine matrine induce apoptosis in human esophageal squamous cancer KYSE-150 cells through increasing reactive oxygen species and inhibiting mitochondrial function. PMID: 29567333 Ref: Autophagy inhibition enhances radiosensitivity of Eca109 cells via the mitochondrial apoptosis pathway. PMID: 29620258 Ref: Chemoresistance to Cancer Treatment: Benzo-alpha-Pyrene as Friend or Foe? PMID: 29673198 Ref: Survivin is critically involved in VEGFR2 signaling-mediated esophageal cancer cell survival. PMID: 30086460 Ref: The Curcumin Analogs 2-Pyridyl Cyclohexanone Induce Apoptosis via Inhibition of the JAK2-STAT3 Pathway in Human Esophageal Squamous Cell Carcinoma Cells. PMID: 30186159 Ref: Effects of zerumbone on proliferation and apoptosis of esophageal cancer cells and on P53 and Bcl-2 expression levels. PMID: 30197671 Ref: Oridonin-induced mitochondria-dependent apoptosis in esophageal cancer cells by inhibiting PI3K/AKT/mTOR and Ras/Raf pathways. PMID: 30229997 |