Primary Site >> Esophagus Cancer
Gene >> BAX
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Ref: Expression of Bax, a pro-apoptotic member of the Bcl-2 family, in esophageal squamous cell carcinoma. PMID: 9389564 |
Ref: Alpha-difluoromethylornithine inhibits N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in zinc-deficient rats: effects on esophageal cell proliferation and apoptosis. PMID: 9850069 Ref: Expression of apoptosis-regulating proteins and outcome of esophageal cancer patients treated by combined therapy modalities. PMID: 9865911 |
Ref: [Histological and molecular prognostic factors in esophageal cancer]. PMID: 10714193 Ref: [In vitro and in vivo studies on the biologic effects and molecular mechanism of recombinant RA538 and antisense C-myc adenovirus on human gastric, esophageal and cancer cell lines with high-expression of Bcl-2 gene]. PMID: 12532785 |
Ref: Modern pathology: prognostic parameters in squamous cell carcinoma of the esophagus. PMID: 10693235 Ref: High frequency in esophageal cancers of p53 alterations inactivating the regulation of genes involved in cell cycle and apoptosis. PMID: 10753186 Ref: Altered mechanisms of apoptosis in colon cancer: Fas resistance and counterattack in the tumor-immune conflict. PMID: 10911913 Ref: Expression of p53, bcl-2, and bax as predictors of response to radiotherapy in esophageal cancer. PMID: 11206630 Ref: [Morphological changes of mitochondria in apoptosis of esophageal carcinoma cells induced by As(2)O(3)]. PMID: 11866913 Ref: Upregulation of bax Gene Expression Promotes Paclitaxel-induced Apoptosis in Esophageal Carcinoma Cells. PMID: 12075422 |
Ref: Bax expression as a prognostic marker of postoperative chemoradiotherapy for patients with esophageal cancer. PMID: 11254884 Ref: Clinical and experimental evidence of Bcl-2 involvement in the response to photodynamic therapy. PMID: 11299823 Ref: Alpha-difluoromethylornithine induction of apoptosis: a mechanism which reverses pre-established cell proliferation and cancer initiation in esophageal carcinogenesis in zinc-deficient rats. PMID: 11303587 Ref: Genistein, a tyrosine kinase inhibitor, enhanced radiosensitivity in human esophageal cancer cell lines in vitro: possible involvement of inhibition of survival signal transduction pathways. PMID: 11316564 Ref: Induction of apoptosis by cyclo-oxygenase-2 inhibitor NS398 through a cytochrome C-dependent pathway in esophageal cancer cells. PMID: 11410869 Ref: Clinical significance and prognostic value of apoptosis related proteins in superficial esophageal squamous cell carcinoma. PMID: 11508622 Ref: Esophageal cancer prevention in zinc-deficient rats: rapid induction of apoptosis by replenishing zinc. PMID: 11604475 Ref: Expression of nitrotyrosine is associated with angiogenesis in esophageal squamous cell carcinoma. PMID: 11848490 |
Ref: Molecular and genetic characterization of a non-metastatic human esophageal cancer cell line, T.Tn expressing non-functional mutated p53. PMID: 12168098 |
Ref: Resveratrol induces apoptosis in human esophageal carcinoma cells. PMID: 12632486 Ref: Interleukin-6 acts as an antiapoptotic factor in human esophageal carcinoma cells through the activation of both STAT3 and mitogen-activated protein kinase pathways. PMID: 14586407 Ref: [Study on the molecular mechanism of apoptosis in esophageal cancer cells induced by soybean isoflavone]. PMID: 14687509 Ref: Epidermal growth factor receptor, p53 mutation, and pathological response predict survival in patients with locally advanced esophageal cancer treated with preoperative chemoradiotherapy. PMID: 14695149 |
Ref: Bax is an important determinant for radiation sensitivity in esophageal carcinoma cells. PMID: 15375604 |
Ref: Frequent microsatellite instability in primary esophageal carcinoma associated with extraesophageal primary carcinoma. PMID: 15540218 Ref: The cytostatic and cytotoxic effects of oridonin (Rubescenin), a diterpenoid from Rabdosia rubescens, on tumor cells of different lineage. PMID: 15703811 Ref: Bax/Bcl-2 expression levels of 2-methoxyestradiol-exposed esophageal cancer cells. PMID: 16011306 Ref: Bile salts inhibit growth and induce apoptosis of human esophageal cancer cell line. PMID: 16127738 Ref: KLF4 and KLF5 regulate proliferation, apoptosis and invasion in esophageal cancer cells. PMID: 16357509 |
Ref: Expression of Egr-1 gene and its correlation with the oncogene proteins in non-irradiated and irradiated esophageal squamous cell carcinoma. PMID: 16866858 |
Ref: Anticancer effects of gallic acid isolated from Indonesian herbal medicine, Phaleria macrocarpa (Scheff.) Boerl, on human cancer cell lines. PMID: 17273761 Ref: The flavonoid component isorhamnetin in vitro inhibits proliferation and induces apoptosis in Eca-109 cells. PMID: 17368593 Ref: [Effects and mechanism of lutein on apoptosis of esophageal carcinoma EC9706 cells]. PMID: 17455471 Ref: Bax upregulation may provide a rationale for the low incidence of esophageal adenocarcinoma in a Greek cohort of patients with Barrett's esophagus. PMID: 17591046 |
Ref: Antiproliferation and apoptosis induction of paeonol in human esophageal cancer cell lines. PMID: 18522637 Ref: Effects of Oxymatrine on the apoptosis of human esophageal carcinoma Eca109 cell line and its mechanism. PMID: 18563331 |
Ref: Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis. PMID: 19073162 |
Ref: Down-regulation of miR-27a might reverse multidrug resistance of esophageal squamous cell carcinoma. PMID: 19960259 Ref: CHAP31 induces apoptosis only via the intrinsic pathway in human esophageal cancer cells. PMID: 20215787 Ref: The prognostic and chemotherapeutic value of miR-296 in esophageal squamous cell carcinoma. PMID: 20485139 Ref: Cyclooxygenase-2 inhibitor NS398 enhances radiosensitivity of radioresistant esophageal cancer cells by inhibiting AKT activation and inducing apoptosis. PMID: 20486853 Ref: Expression of Bmi-1 gene in esophageal carcinoma cell EC9706 and its effect on cell cycle, apoptosis and migration. PMID: 20591222 Ref: [Effect of gecko alcohol extract on human esophageal squamous carcinoma cell line EC9706 and anti-tumor activity in vivo]. PMID: 21046756 |
Ref: Effect and mechanism of 5-aminolevulinic acid-mediated photodynamic therapy in esophageal cancer. PMID: 20676910 Ref: Correlation between tumor-associated proteins and response to neoadjuvant treatment in patients with advanced squamous-cell esophageal cancer. PMID: 21617238 |
Ref: The -938A/A genotype of BCL2 gene is associated with esophageal cancer. PMID: 22187149 Ref: Curcumin induces cell death in esophageal cancer cells through modulating Notch signaling. PMID: 22363450 Ref: PSK induces apoptosis through the inhibition of activated STAT3 in human esophageal carcinoma cells. PMID: 22552778 Ref: Early evaluation of the apoptotic index ratio is useful in predicting the efficacy of chemoradiotherapy in esophageal squamous cell carcinoma. PMID: 22740896 Ref: Effect of altered WIG-1 expression on DDP sensitivity in a DDP-resistant esophageal squamous cancer cell line. PMID: 22794122 Ref: Antitumor activity of folate-targeted, paclitaxel-loaded polymeric micelles on a human esophageal EC9706 cancer cell line. PMID: 22848173 Ref: [Small interfering RNA in silencing cox-2 expression enhances radiosensitivity of esophageal cancer EC9706 cell]. PMID: 22944132 Ref: Intervention effects of nedaplatin and cisplatin on proliferation and apoptosis of human tumour cells in vitro. PMID: 23167374 |
Ref: The variability of oxLDL-induced cytotoxicity on different types of cell lines. PMID: 23479334 Ref: Initiation of apoptosis, cell cycle arrest and autophagy of esophageal cancer cells by dihydroartemisinin. PMID: 23582790 Ref: Jaridonin, a novel ent-kaurene diterpenoid from Isodon rubescens, inducing apoptosis via production of reactive oxygen species in esophageal cancer cells. PMID: 23597192 Ref: Restoring KLF5 in esophageal squamous cell cancer cells activates the JNK pathway leading to apoptosis and reduced cell survival. PMID: 23633919 Ref: OSU-03012, a non-Cox inhibiting celecoxib derivative, induces apoptosis of human esophageal carcinoma cells through a p53/Bax/cytochrome c/caspase-9-dependent pathway. PMID: 23652278 Ref: [Effects of deguelin on the proliferation and apoptosis of human esophageal cancer cell Ec-109: an experimental research]. PMID: 23713258 Ref: Phaseoloideside E, a novel natural triterpenoid saponin identified from Entada phaseoloides, induces apoptosis in Ec-109 esophageal cancer cells through reactive oxygen species generation. PMID: 23782641 Ref: Small proline-rich repeat protein 3 enhances the sensitivity of esophageal cancer cells in response to DNA damage-induced apoptosis. PMID: 23820115 Ref: The radiation-sensitizing effect of flavopiridol in the esophageal cancer cell line Eca109. PMID: 23833659 Ref: Hugl-1 induces apoptosis in esophageal carcinoma cells both in vitro and in vivo. PMID: 23864775 Ref: Establishment and characterization of a paclitaxelresistant human esophageal carcinoma cell line. PMID: 24002547 Ref: Cooperative inhibitory effect of sinomenine combined with 5-fluorouracil on esophageal carcinoma. PMID: 24363520 |
Ref: Association between SNPs in P53 binding regions and risk of esophageal squamous cell carcinoma. PMID: 24474449 Ref: Anti-tumor activity and relative mechanism of ethanolic extract of Marsdenia tenacissima (Asclepiadaceae) against human hematologic neoplasm in vitro and in vivo. PMID: 24583069 Ref: Obatoclax induces G1/G0-phase arrest via p38/p21(waf1/Cip1) signaling pathway in human esophageal cancer cells. PMID: 24788582 Ref: The molecular mechanisms of Tanshinone IIA on the apoptosis and arrest of human esophageal carcinoma cells. PMID: 24829906 Ref: Anti-tumor effects of flavonoids from the ethnic medicine Docynia delavayi (Franch.) Schneid. and its possible mechanism. PMID: 24940817 Ref: Inhibition of mammalian target of rapamycin by rapamycin increases the radiosensitivity of esophageal carcinoma Eca109 cells. PMID: 25009644 Ref: DADS suppresses human esophageal xenograft tumors through RAF/MEK/ERK and mitochondria-dependent pathways. PMID: 25026173 Ref: Effect of ECRG2 in combination with cisplatin on the proliferation and apoptosis of EC9706 cells. PMID: 25289046 |
Ref: Ternary copper(II) complexes with amino acid chains and heterocyclic bases: DNA binding, cytotoxic and cell apoptosis induction properties. PMID: 25555321 Ref: Anticancer effects of crocetin in human esophageal squamous cell carcinoma KYSE-150 cells. PMID: 25663893 Ref: Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells. PMID: 25733817 Ref: Artesunate induces apoptosis and inhibits growth of Eca109 and Ec9706 human esophageal cancer cell lines in vitro and in vivo. PMID: 25816175 Ref: Cranberry proanthocyanidins inhibit esophageal adenocarcinoma in vitro and in vivo through pleiotropic cell death induction and PI3K/AKT/mTOR inactivation. PMID: 26378019 Ref: Compound Radix Sophorae Flavescentis exerts antitumor effects by inhibiting the proliferation and inducing the apoptosis of esophageal carcinoma TE-8 cells. PMID: 26622820 |
Ref: Andrographolide radiosensitizes human esophageal cancer cell line ECA109 to radiation in vitro. PMID: 25059546 Ref: Hesperetin induces apoptosis of esophageal cancer cells via mitochondrial pathway mediated by the increased intracellular reactive oxygen species. PMID: 26449828 Ref: Traditional Chinese medicine targeting apoptotic mechanisms for esophageal cancer therapy. PMID: 26707140 Ref: Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression. PMID: 26936624 Ref: Costunolide Induces Apoptosis through Generation of ROS and Activation of P53 in Human Esophageal Cancer Eca-109 Cells. PMID: 27078502 Ref: Downregulation of Ubiquitin-conjugating Enzyme UBE2D3 Promotes Telomere Maintenance and Radioresistance of Eca-109 Human Esophageal Carcinoma Cells. PMID: 27326259 Ref: Thioridazine Sensitizes Esophageal Carcinoma Cell Lines to Radiotherapy-Induced Apoptosis In Vitro and In Vivo. PMID: 27453171 Ref: beta-Carotene synergistically enhances the anti-tumor effect of 5-fluorouracil on esophageal squamous cell carcinoma in vivo and in vitro. PMID: 27586268 Ref: Induction of the mitochondria-mediated apoptosis in human esophageal cancer cells by DS2, a newly synthetic diterpenoid analog, is regulated by Bax and caused by generation of reactive oxygen species. PMID: 27863415 Ref: [Knockdown of NEDD9 inhibits the proliferation, invasion and migration of esophageal carcinoma EC109 cells]. PMID: 27916098 |
Ref: Capilliposide C Sensitizes Esophageal Squamous Carcinoma Cells to Oxaliplatin by Inducing Apoptosis Through the PI3K/Akt/mTOR Pathway. PMID: 28463955 Ref: miR-195 Regulates Proliferation and Apoptosis through Inhibiting the mTOR/p70s6k Signaling Pathway by Targeting HMGA2 in Esophageal Carcinoma Cells. PMID: 28487599 Ref: Azoxystrobin Induces Apoptosis of Human Esophageal Squamous Cell Carcinoma KYSE-150 Cells through Triggering of the Mitochondrial Pathway. PMID: 28567017 Ref: Design and synthesis of novel N()-substituted thiosemicarbazones bearing a pyrrole unit as potential anticancer agents. PMID: 28599449 Ref: Endoplasmic reticulum stress could induce autophagy and apoptosis and enhance chemotherapy sensitivity in human esophageal cancer EC9706 cells by mediating PI3K/Akt/mTOR signaling pathway. PMID: 28631572 Ref: RNAi-mediated TCF-3 gene silencing inhibits proliferation of Eca-109 esophageal cancer cells by inducing apoptosis. PMID: 28864779 Ref: Antitumor activity of Lobaplatin against esophageal squamous cell carcinoma through caspase-dependent apoptosis and increasing the Bax/Bcl-2 ratio. PMID: 28865364 Ref: Downregulation of esophageal cancer-related gene 4 promotes proliferation and migration of hepatocellular carcinoma. PMID: 28927132 Ref: Epigallocatechin-3-gallate promotes apoptosis and reversal of multidrug resistance in esophageal cancer cells. PMID: 28964574 Ref: Low-dose hyperthermia enhances the antitumor effects of chemotherapy in squamous cell carcinoma. PMID: 30052898 |
Ref: Differentially expressed proteins in the human esophageal cancer cell line Eca109, in the presence and absence of gemcitabine. PMID: 29138856 Ref: Thymoquinone Augments Cisplatin-Induced Apoptosis on Esophageal Carcinoma Through Mitigating the Activation of JAK2/STAT3 Pathway. PMID: 29197940 Ref: Potent hydrazone derivatives targeting esophageal cancer cells. PMID: 29475156 Ref: Chinese herb medicine matrine induce apoptosis in human esophageal squamous cancer KYSE-150 cells through increasing reactive oxygen species and inhibiting mitochondrial function. PMID: 29567333 Ref: Autophagy inhibition enhances radiosensitivity of Eca109 cells via the mitochondrial apoptosis pathway. PMID: 29620258 Ref: C-terminal binding protein2 mediates cisplatin chemoresistance in esophageal cancer cells via the inhibition of apoptosis. PMID: 29658564 Ref: Effect of GDF11 on proliferation and apoptosis of esophageal cancer cells. PMID: 30213293 Ref: Oridonin-induced mitochondria-dependent apoptosis in esophageal cancer cells by inhibiting PI3K/AKT/mTOR and Ras/Raf pathways. PMID: 30229997 Ref: Liriodenine enhances radiosensitivity in esophageal cancer ECA-109 cells by inducing apoptosis and G2/M arrest. PMID: 30250568 |