Primary Site >> Biliary tract Cancer
Gene >> BAX
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Ref: Bcl-2 is overexpressed and alters the threshold for apoptosis in a cholangiocarcinoma cell line. PMID: 9328309 |
Ref: Losses of heterozygosity on chromosomes 17p and 9p/18q may play important roles in early and advanced phases of gallbladder carcinogenesis. PMID: 10480335 |
Ref: Genetic alterations involved in the development of gallbladder carcinomas from Greek patients. PMID: 11677947 Ref: Detailed tissue expression of bcl-2, bax, bak and bcl-x in the normal human pancreas and in chronic pancreatitis, ampullary and pancreatic ductal adenocarcinomas. PMID: 12120204 |
Ref: IFN-gammaupregulates apoptosis-related molecules and enhances Fas-mediated apoptosis in human cholangiocarcinoma. PMID: 12115528 |
Ref: Homozygous deletion scanning in hepatobiliary tumor cell lines reveals alternative pathways for liver carcinogenesis. PMID: 12668978 Ref: Expression of Bcl-2 and Bax in extrahepatic biliary tract carcinoma and dysplasia. PMID: 14606101 Ref: Evaluation of BAT-26 as an indicator of microsatellite instability in gallbladder carcinomas. PMID: 14696408 Ref: Correlated expression of inducible nitric oxide synthase and P53, Bax in benign and malignant diseased gallbladder. PMID: 14704000 |
Ref: Celecoxib-induced apoptosis in rat cholangiocarcinoma cells mediated by Akt inactivation and Bax translocation. PMID: 15057907 Ref: Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells. PMID: 15150106 Ref: Detection of bcl-2 and bax expression and bcl-2/JH fusion gene in intrahepatic cholangiocarcinoma. PMID: 15484294 |
Ref: Prognostic value of Bax, Bcl-2, p53, and TUNEL staining in patients with radically resected ampullary carcinoma. PMID: 15677536 Ref: Susceptibility of cholangiocarcinoma cells to parthenolide-induced apoptosis. PMID: 16024633 |
Ref: High-level microsatellite instability is not involved in gallbladder carcinogenesis. PMID: 15963980 Ref: [Anti-tumor mechanism of norcantharidin for the implanted tumors of human gallbladder carcinoma in nude mice in vivo]. PMID: 16784656 Ref: The associated expression of Maspin and Bax proteins as a potential prognostic factor in intrahepatic cholangiocarcinoma. PMID: 17067385 |
Ref: Inhibitory effect of norcantharidin on the growth of human gallbladder carcinoma GBC-SD cells in vitro. PMID: 17287171 Ref: Histone deacetylase inhibitor MS-275 alone or combined with bortezomib or sorafenib exhibits strong antiproliferative action in human cholangiocarcinoma cells. PMID: 17724801 |
Ref: Thalidomide attenuates tumor growth and preserves fast-twitch skeletal muscle fibers in cholangiocarcinoma rats. PMID: 18291259 Ref: Paclitaxel augments cytotoxic effect of photodynamic therapy using verteporfin in gastric and bile duct cancer cells. PMID: 18597023 Ref: BH3-only protein mimetic obatoclax sensitizes cholangiocarcinoma cells to Apo2L/TRAIL-induced apoptosis. PMID: 18723481 Ref: Decreased expression of Bax-interacting factor-1 (Bif-1) in invasive urinary bladder and gallbladder cancers. PMID: 18752120 Ref: Clinical significance of cell cycle- and apoptosis-related markers in biliary tract cancer: a tissue microarray-based approach revealing a distinctive immunophenotype for intrahepatic and extrahepatic cholangiocarcinomas. PMID: 18854271 Ref: Immunophenotyping and oncogene amplifications in tumors of the papilla of Vater. PMID: 18936968 |
Ref: Caffeic acid phenethyl ester decreases cholangiocarcinoma growth by inhibition of NF-kappaB and induction of apoptosis. PMID: 19358267 Ref: Somatostatin enhances the chemosensitivity of GBC-SD cell line to doxorubicin through arresting the cell cycle to S phase rather than through the P53/Bax-depended apoptosis way in vitro. PMID: 19950772 |
Ref: Apoptotic activity of caged xanthones from Garcinia hanburyi in cholangiocarcinoma cell lines. PMID: 20458760 Ref: Redox modulation and human bile duct cancer inhibition by curcumin. PMID: 20510329 Ref: Norcantharidin inhibits growth of human gallbladder carcinoma xenografted tumors in nude mice by inducing apoptosis and blocking the cell cycle in vivo. PMID: 20688607 Ref: Prostate apoptosis response-4 is expressed in normal cholangiocytes, is down-regulated in human cholangiocarcinoma, and promotes apoptosis of neoplastic cholangiocytes when induced pharmacologically. PMID: 20724592 |
Ref: Acquisition of chemoresistance in intrahepatic cholangiocarcinoma cells by activation of AKT and extracellular signal-regulated kinase (ERK)1/2. PMID: 21130731 Ref: Apoptosis of human cholangiocarcinoma cell lines induced by beta-escin through mitochondrial caspase-dependent pathway. PMID: 21394804 Ref: Overexpression of LAPTM4B-35 attenuates epirubucin-induced apoptosis of gallbladder carcinoma GBC-SD cells. PMID: 21429547 Ref: [Expression of WW domain containing oxidoreductase gene in cholangiocarcinoma and its effect on the biological behavior of cancer cell line RBE]. PMID: 21612698 |
Ref: Effects of matrine on proliferation and apoptosis in gallbladder carcinoma cells (GBC-SD). PMID: 22162124 Ref: Apoptosis mechanism of human cholangiocarcinoma cells induced by bile extract from crocodile. PMID: 22194052 Ref: Correlation between promoter methylation of p14(ARF), TMS1/ASC, and DAPK, and p53 mutation with prognosis in cholangiocarcinoma. PMID: 22230750 Ref: Adenovirus-mediated gene transfer of tissue factor pathway inhibitor-2 inhibits gallbladder carcinoma growth in vitro and in vivo. PMID: 22320835 Ref: Lobaplatin induces apoptosis and arrests cell cycle progression in human cholangiocarcinoma cell line RBE. PMID: 22425181 Ref: Effects of Helicobacter pylori gamma-glutamyltranspeptidase on apoptosis and inflammation in human biliary cells. PMID: 22581342 Ref: [The role of tissue factor pathway inhibitor-2 gene in gallbladder cancer]. PMID: 23336488 |
Ref: Oncogenic potential of cyclin kinase subunit-2 in cholangiocarcinoma. PMID: 23121546 Ref: Antiproliferative and apoptosis-inducing activity of curcumin against human gallbladder adenocarcinoma cells. PMID: 23645731 Ref: Curcumin induces apoptosis in gallbladder carcinoma cell line GBC-SD cells. PMID: 23802572 Ref: Phenethyl isothiocyanate induces apoptosis of cholangiocarcinoma cells through interruption of glutathione and mitochondrial pathway. PMID: 23949086 |
Ref: Partial characterization of proapoptotic action of biliary deteriorated lipids on biliary epithelial cells in pancreaticobiliary diseases. PMID: 23894007 Ref: WW domain containing oxidoreductase induces apoptosis in gallbladder-derived malignant cell by upregulating expression of P73 and PUMA. PMID: 24127039 Ref: Inhibitory effects of deleted in liver cancer 1 gene on gallbladder cancer growth through induction of cell cycle arrest and apoptosis. PMID: 24329682 Ref: Induction of apoptosis in cholangiocarcinoma by an andrographolide analogue is mediated through topoisomerase II alpha inhibition. PMID: 24360936 Ref: Baicalin induces apoptosis of gallbladder carcinoma cells in vitro via a mitochondrial-mediated pathway and suppresses tumor growth in vivo. PMID: 24568162 Ref: Oridonin induces apoptosis and cell cycle arrest of gallbladder cancer cells via the mitochondrial pathway. PMID: 24655726 Ref: UHRF1 depletion suppresses growth of gallbladder cancer cells through induction of apoptosis and cell cycle arrest. PMID: 24756644 Ref: Andrographis paniculata extracts and major constituent diterpenoids inhibit growth of intrahepatic cholangiocarcinoma cells by inducing cell cycle arrest and apoptosis. PMID: 24782229 Ref: Effects of oxymatrine on the apoptosis and proliferation of gallbladder cancer cells. PMID: 24869760 Ref: Expression of Ki-67, Bax and p73 in patients with hilar cholangiocarcinoma. PMID: 24934361 Ref: Tetrandrine induces apoptosis in gallbladder carcinoma in vitro. PMID: 25074868 Ref: Cordycepin induces S phase arrest and apoptosis in human gallbladder cancer cells. PMID: 25090123 Ref: Schisandrin B induces apoptosis and cell cycle arrest of gallbladder cancer cells. PMID: 25165862 |
Ref: Maslinic acid potentiates the antitumor activities of gemcitabine in vitro and in vivo by inhibiting NF-kappaB-mediated survival signaling pathways in human gallbladder cancer cells. PMID: 25633045 Ref: MiR-138 Suppresses Cell Proliferation by Targeting Bag-1 in Gallbladder Carcinoma. PMID: 25962180 Ref: Involvement of PSMD10, CDK4, and Tumor Suppressors in Development of Intrahepatic Cholangiocarcinoma of Syrian Golden Hamsters Induced by Clonorchis sinensis and N-Nitrosodimethylamine. PMID: 26313366 |
Ref: Significance of S100P as a biomarker in diagnosis, prognosis and therapy of opisthorchiasis-associated cholangiocarcinoma. PMID: 26312563 Ref: Simvastatin Induces Apoptosis and Suppresses Insulin-Like Growth Factor 1 Receptor in Bile Duct Cancer Cells. PMID: 26470769 Ref: Scabraside D Extracted from Holothuria scabra Induces Apoptosis and Inhibits Growth of Human Cholangiocarcinoma Xenografts in Mice. PMID: 26925636 Ref: Schisandrin B inhibits cell proliferation and induces apoptosis in human cholangiocarcinoma cells. PMID: 27499090 |
Ref: Casticin induces apoptosis and G0/G1 cell cycle arrest in gallbladder cancer cells. PMID: 28070171 Ref: Growth Inhibition of Refractory Human Gallbladder Cancer Cells by Retinol, and Its Mechanism of Action. PMID: 28100868 Ref: Long Noncoding RNA MNX1-AS1 Knockdown Inhibits Cell Proliferation and Migration in Ovarian Cancer. PMID: 28414551 Ref: Cryptotanshinone induces cell cycle arrest and apoptosis through the JAK2/STAT3 and PI3K/Akt/NFkappaB pathways in cholangiocarcinoma cells. PMID: 28670110 Ref: Osthole induces apoptosis and suppresses proliferation via the PI3K/Akt pathway in intrahepatic cholangiocarcinoma. PMID: 28902342 Ref: Upregulation of B7-H4 promotes tumor progression of intrahepatic cholangiocarcinoma. PMID: 29235470 |
Ref: Oxymatrine induces apoptosis and inhibits invasion in Gallbladder carcinoma via PTEN/PI3K/AKT pathway. PMID: 29170841 Ref: Characterization and prognostic significance of mortalin, Bcl-2 and Bax in intrahepatic cholangiocarcinoma. PMID: 29434920 Ref: Tea polyphenols induce S phase arrest and apoptosis in gallbladder cancer cells. PMID: 29513793 Ref: Anti-cancer activity of asiatic acid against human cholangiocarcinoma cells through inhibition of proliferation and induction of apoptosis. PMID: 30084792 Ref: Phytochemical analysis and antioxidant and anticancer activities of mastic gum resin from Pistacia atlantica subspecies kurdica. PMID: 30122948 Ref: Isocitrate dehydrogenase 1 mutation sensitizes intrahepatic cholangiocarcinoma to the BET inhibitor JQ1. PMID: 30156013 |