Primary Site >> Biliary tract Cancer
Gene >> BAP1
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Ref: Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers. PMID: 24185513 |
Ref: Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications. PMID: 25536104 |
Ref: Molecular diagnosis of intrahepatic cholangiocarcinoma. PMID: 25267595 Ref: Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity. PMID: 25636086 Ref: Pathogenesis of cholangiocarcinoma: From genetics to signalling pathways. PMID: 25966424 |
Ref: Molecular Pathogenesis and Targeted Therapies for Intrahepatic Cholangiocarcinoma. PMID: 26405193 Ref: Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients. PMID: 26717940 Ref: Loss of BAP1 Expression Occurs Frequently in Intrahepatic Cholangiocarcinoma. PMID: 26765459 Ref: Loss of BAP1 Expression Is Very Rare in Pancreatic Ductal Adenocarcinoma. PMID: 26982343 Ref: The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets. PMID: 27102149 Ref: BRCA-associated protein 1 mutant cholangiocarcinoma: an aggressive disease subtype. PMID: 27563445 |
Ref: Intrahepatic cholangiocarcinoma frequently shows loss of BAP1 and PBRM1 expression, and demonstrates specific clinicopathological and genetic characteristics with BAP1 loss. PMID: 27864835 Ref: BAP1 dependent expression of long non-coding RNA NEAT-1 contributes to sensitivity to gemcitabine in cholangiocarcinoma. PMID: 28122578 Ref: Dichotomy in intrahepatic cholangiocarcinomas based on histologic similarities to hilar cholangiocarcinomas. PMID: 28338651 Ref: Somatic BRCA1-associated protein 1 (BAP1) loss is an early and rare event in esophageal adenocarcinoma. PMID: 28781790 Ref: Mutations of candidate tumor suppressor genes at chromosome 3p in intrahepatic cholangiocarcinoma. PMID: 29122566 |
Ref: Novel targeted therapy strategies for biliary tract cancers and hepatocellular carcinoma. PMID: 29460642 Ref: Molecular genomic landscapes of hepatobiliary cancer. PMID: 29573058 Ref: Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for Intervention. PMID: 29848569 Ref: Emergence of Intrahepatic Cholangiocarcinoma: How High-Throughput Technologies Expedite the Solutions for a Rare Cancer Type. PMID: 30158952 Ref: Histological and molecular characterization of intrahepatic bile duct cancers suggests an expanded definition of perihilar cholangiocarcinoma. PMID: 30170977 Ref: BAP1 acts as a tumor suppressor in intrahepatic cholangiocarcinoma by modulating the ERK1/2 and JNK/c-Jun pathways. PMID: 30305612 Ref: Prognostic role of BAP-1 and PBRM-1 expression in intrahepatic cholangiocarcinoma. PMID: 30377796 |