Primary Site >> Pancreatic Cancer

Gene >> AXIN1

  • 2011
  • 2015
  • 2016
  • 2018
Ref: Omega-3-polyunsaturated fatty acids suppress pancreatic cancer cell growth in vitro and in vivo via downregulation of Wnt/Beta-catenin signaling.
PMID: 22213040
Ref: Inhibition of beta-catenin signaling suppresses pancreatic tumor growth by disrupting nuclear beta-catenin/TCF-1 complex: critical role of STAT-3.
PMID: 25869100
Ref: Loss of tumor suppressor Merlin results in aberrant activation of Wnt/beta-catenin signaling in cancer.
PMID: 26908451
Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
PMID: 29786110
Ref: Therapeutic potential of targeting the Wnt/beta-catenin pathway in the treatment of pancreatic cancer.
PMID: 30368889