Primary Site >> Liver Cancer
Gene >> ATR
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Ref: A novel sensitive method to detect frameshift mutations in exonic repeat sequences of cancer-related genes. PMID: 10545425 |
Ref: Somatic mutations in the DNA damage-response genes ATR and CHK1 in sporadic stomach tumors with microsatellite instability. PMID: 11691784 |
Ref: Heterozygous ATR mutations in mismatch repair-deficient cancer cells have functional significance. PMID: 16103057 |
Ref: Gastric cancer with high-level microsatellite instability: target gene mutations, clinicopathologic features, and long-term survival. PMID: 18440592 |
Ref: Growth inhibitory effect and Chk1-dependent signaling involved in G2/M arrest on human gastric cancer cells induced by diallyl disulfide. PMID: 20401435 |
Ref: Pteridium aquilinum and its ptaquiloside toxin induce DNA damage response in gastric epithelial cells, a link with gastric carcinogenesis. PMID: 22143989 |
Ref: Loss of BRCA1 expression leads to worse survival in patients with gastric carcinoma. PMID: 23569343 |
Ref: Diallyl disulfide selectively causes checkpoint kinase-1 mediated G2/M arrest in human MGC803 gastric cancer cell line. PMID: 25176258 |
Ref: AZD6738, A Novel Oral Inhibitor of ATR, Induces Synthetic Lethality with ATM Deficiency in Gastric Cancer Cells. PMID: 28138034 Ref: Genetic Gastric Cancer Susceptibility in the International Clinical Cancer Genomics Community Research Network. PMID: 29025585 Ref: Epstein-Barr Virus Hijacks DNA Damage Response Transducers to Orchestrate Its Life Cycle. PMID: 29144413 |
Ref: Chk1 activation attenuates sensitivity of lapatinib in HER2-positive gastric cancer. PMID: 29271513 Ref: A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening. PMID: 30344100 Ref: pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry. PMID: 30385821 |