Primary Site >> Stomach Cancer
Gene >> ATM
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Identification of a tumor-associated target antigen, ATM-1, for a human T-cell clone with activated killer activity and its existence in sera of cancer patients. PMID: 3044579 |
Ref: Alteration of immunoreactivity by hydrated autoclaving, microwave treatment, and simple heating of paraffin-embedded tissue sections. PMID: 7516673 |
Ref: No evidence for constitutional ATM mutation in breast/gastric cancer families. PMID: 9592204 |
Ref: Somatic mutations in the DNA damage-response genes ATR and CHK1 in sporadic stomach tumors with microsatellite instability. PMID: 11691784 |
Ref: Involvement of ATM/ATR-p38 MAPK cascade in MNNG induced G1-S arrest. PMID: 12970909 |
Ref: Alteration of the ATM gene occurs in gastric cancer cell lines and primary tumors associated with cellular response to DNA damage. PMID: 14706517 |
Ref: Cancer risks and mortality in heterozygous ATM mutation carriers. PMID: 15928302 |
Ref: Analysis of common gene expression patterns in four human tumor cell lines exposed to camptothecin using cDNA microarray: identification of topoisomerase-mediated DNA damage response pathways. PMID: 16368568 Ref: TRF2 promotes multidrug resistance in gastric cancer cells. PMID: 16760674 |
Ref: Molecular analysis of primary gastric cancer, corresponding xenografts, and 2 novel gastric carcinoma cell lines reveals novel alterations in gastric carcinogenesis. PMID: 17376510 Ref: Novel NBS1 heterozygous germ line mutation causing MRE11-binding domain loss predisposes to common types of cancer. PMID: 18056440 |
Ref: Expression status of ataxia-telangiectasia-mutated gene correlated with prognosis in advanced gastric cancer. PMID: 17928013 Ref: The effect of docetaxel (taxotere) on human gastric cancer cells exhibiting low-dose radiation hypersensitivity. PMID: 21892291 |
Ref: Gene expression profiling in TWIST-depleted gastric cancer cells. PMID: 19051271 Ref: Mechanism of beta-carotene-induced apoptosis of gastric cancer cells: involvement of ataxia-telangiectasia-mutated. PMID: 19723050 |
Ref: Telomeric plasmid induces human cancer cell dysfunction depending on ATM activity. PMID: 20535839 |
Ref: A crucial role for bone morphogenetic protein-Smad1 signalling in the DNA damage response. PMID: 22588298 |
Ref: Cytotoxicity of 5-Aza-2'-deoxycytidine against gastric cancer involves DNA damage in an ATM-P53 dependent signaling pathway and demethylation of P16(INK4A). PMID: 23201008 Ref: Concordance of ATM (ataxia telangiectasia mutated) immunohistochemistry between biopsy or metastatic tumor samples and primary tumors in gastric cancer patients. PMID: 23328638 Ref: Loss of BRCA1 expression leads to worse survival in patients with gastric carcinoma. PMID: 23569343 Ref: Mutation at intronic repeats of the ataxia-telangiectasia mutated (ATM) gene and ATM protein loss in primary gastric cancer with microsatellite instability. PMID: 24324828 |
Ref: Ataxia-telangiectasia-mutated protein expression with microsatellite instability in gastric cancer as prognostic marker. PMID: 23649938 Ref: DNA damage response-related proteins in gastric cancer: ATM, Chk2 and p53 expression and their prognostic value. PMID: 23969480 Ref: Development of chitosan/heparin nanoparticle-encapsulated cytolethal distending toxin for gastric cancer therapy. PMID: 24024568 Ref: MicroRNA-181a functions as an oncomir in gastric cancer by targeting the tumour suppressor gene ATM. PMID: 24531888 Ref: Low ATM protein expression and depletion of p53 correlates with olaparib sensitivity in gastric cancer cell lines. PMID: 24841718 Ref: Helicobacter pylori infection introduces DNA double-strand breaks in host cells. PMID: 25069978 Ref: PARP inhibitors target ATM+p53-defective gastric cancer. PMID: 25485492 |
Ref: Programmed cell death 2 protein induces gastric cancer cell growth arrest at the early S phase of the cell cycle and apoptosis in a p53-dependent manner. PMID: 25334010 Ref: Rap1 is indispensable for TRF2 function in etoposide-induced DNA damage response in gastric cancer cell line. PMID: 25821946 Ref: Hsa-let-7g miRNA regulates the anti-tumor effects of gastric cancer cells under oxidative stress through the expression of DDR genes. PMID: 25972194 Ref: alpha-Fetoprotein-Producing Hepatoid Gastric Adenocarcinoma With Osteoclast-Like Giant Cells and Neuroendocrine Differentiation: A Case Study With Molecular Profiling. PMID: 26009570 Ref: Loss-of-function variants in ATM confer risk of gastric cancer. PMID: 26098866 Ref: Hereditary Diffuse Gastric Cancer Syndrome: CDH1 Mutations and Beyond. PMID: 26182300 Ref: Randomized, Double-Blind Phase II Trial With Prospective Classification by ATM Protein Level to Evaluate the Efficacy and Tolerability of Olaparib Plus Paclitaxel in Patients With Recurrent or Metastatic Gastric Cancer. PMID: 26282658 Ref: Targeted therapy for Epstein-Barr virus-associated gastric carcinoma using low-dose gemcitabine-induced lytic activation. PMID: 26427042 Ref: Prevalence of deleterious ATM germline mutations in gastric cancer patients. PMID: 26506520 Ref: Intra-Tumoral Heterogeneity of HER2, FGFR2, cMET and ATM in Gastric Cancer: Optimizing Personalized Healthcare through Innovative Pathological and Statistical Analysis. PMID: 26587992 Ref: Patterns and functional implications of rare germline variants across 12 cancer types. PMID: 26689913 |
Ref: Inhibition of class I histone deacetylases by romidepsin potently induces Epstein-Barr virus lytic cycle and mediates enhanced cell death with ganciclovir. PMID: 26205347 Ref: Distinct miRNA profiles in normal and gastric cancer myofibroblasts and significance in Wnt signaling. PMID: 26939869 Ref: [Jaridonin, a new diterpenoid from Isodon rubescens, induces cell cycle arrest in gastric cancer cells through activating ataxia telangiectasia mutated kinase]. PMID: 27087371 Ref: miR-30a can inhibit DNA replication by targeting RPA1 thus slowing cancer cell proliferation. PMID: 27208176 Ref: MiR-203 inhibits tumor invasion and metastasis in gastric cancer by ATM. PMID: 27542403 Ref: ATM Expression Predicts Veliparib and Irinotecan Sensitivity in Gastric Cancer by Mediating P53-Independent Regulation of Cell Cycle and Apoptosis. PMID: 27638859 |
Ref: Lasiokaurin derivatives: synthesis, antimicrobial and antitumor biological evaluation, and apoptosis-inducing effects. PMID: 28110416 Ref: AZD6738, A Novel Oral Inhibitor of ATR, Induces Synthetic Lethality with ATM Deficiency in Gastric Cancer Cells. PMID: 28138034 Ref: DNA damage repair and survival outcomes in advanced gastric cancer patients treated with first-line chemotherapy. PMID: 28233295 Ref: Effect of diterpenoid kaurenoic acid on genotoxicity and cell cycle progression in gastric cancer cell lines. PMID: 28273639 Ref: Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers. PMID: 28522256 Ref: Decreased expression of the ATM gene linked to poor prognosis for gastric cancer of different nationalities in Xinjiang. PMID: 28647209 Ref: Genetic Gastric Cancer Susceptibility in the International Clinical Cancer Genomics Community Research Network. PMID: 29025585 Ref: Actionable gene-based classification toward precision medicine in gastric cancer. PMID: 29089060 Ref: Olaparib in combination with paclitaxel in patients with advanced gastric cancer who have progressed following first-line therapy (GOLD): a double-blind, randomised, placebo-controlled, phase 3 trial. PMID: 29103871 Ref: Epstein-Barr Virus Hijacks DNA Damage Response Transducers to Orchestrate Its Life Cycle. PMID: 29144413 |
Ref: Gastric poorly cohesive carcinoma: a correlative study of mutational signatures and prognostic significance based on histopathological subtypes. PMID: 28873240 Ref: Epigenetic Mechanisms of ATM Activation after Helicobacter pylori Infection. PMID: 29128564 Ref: Chk1 activation attenuates sensitivity of lapatinib in HER2-positive gastric cancer. PMID: 29271513 Ref: HOXC10 promotes gastric cancer cell invasion and migration via regulation of the NF-kappaB pathway. PMID: 29753747 Ref: (S)-crizotinib reduces gastric cancer growth through oxidative DNA damage and triggers pro-survival akt signal. PMID: 29855474 Ref: FGF18, a prominent player in FGF signaling, promotes gastric tumorigenesis through autocrine manner and is negatively regulated by miR-590-5p. PMID: 30082912 Ref: Conditioned medium mimicking the tumor microenvironment augments chemotherapeutic resistance via ataxiatelangiectasia mutated and nuclear factorkappaB pathways in gastric cancer cells. PMID: 30106453 Ref: Next-generation sequencing reveals mutational accordance between cell-free DNA from plasma, malignant pleural effusion and ascites and directs targeted therapy in a gastric cancer patient. PMID: 30118648 Ref: The clinical significance of PD-L1 in advanced gastric cancer is dependent on ARID1A mutations and ATM expression. PMID: 30221053 Ref: Somatic mutational profiles of stage II and III gastric cancer according to tumor microenvironment immune type. PMID: 30239046 Ref: The silencing of long non-coding RNA ANRIL suppresses invasion, and promotes apoptosis of retinoblastoma cells through ATM-E2F1 signaling pathway. PMID: 30355646 Ref: pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry. PMID: 30385821 |