Primary Site >> Colorectal Cancer

Gene >> ATG12

  • 2009
  • 2014
  • 2015
  • 2018
Ref: Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability.
PMID: 19197948
 Ref: Autophagy promotes resistance to photodynamic therapy-induced apoptosis selectively in colorectal cancer stem-like cells.
PMID: 24905352
 Ref: Justicidin A-induced autophagy flux enhances apoptosis of human colorectal cancer cells via class III PI3K and Atg5 pathway.
PMID: 25216025
Ref: Pan-Bcl-2 inhibitor Obatoclax is a potent late stage autophagy inhibitor in colorectal cancer cells independent of canonical autophagy signaling.
PMID: 26585594
 Ref: Autophagy mediates cytotoxicity of human colorectal cancer cells treated with garcinielliptone FC.
PMID: 28294332
Ref: Oncogenic RAS-induced downregulation of ATG12 is required for survival of malignant intestinal epithelial cells.
PMID: 28933585
Ref: Inhibition of ATG12-mediated autophagy by miR-214 enhances radiosensitivity in colorectal cancer.
PMID: 29459645
Ref: The Influence of Tumor Microenvironment on ATG4D Gene Expression in Colorectal Cancer Patients.
PMID: 30374741