Primary Site >> Stomach Cancer

Gene >> ATF4

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Ref: Effect on tumor cells of blocking survival response to glucose deprivation.
PMID: 15339968
Ref: Celecoxib upregulates endoplasmic reticulum chaperones that inhibit celecoxib-induced apoptosis in human gastric cells.
PMID: 16205636
Ref: Up-regulation of 150-kDa oxygen-regulated protein by celecoxib in human gastric carcinoma cells.
PMID: 17167033
Ref: Involvement of up-regulation of PUMA in non-steroidal anti-inflammatory drug-induced apoptosis.
PMID: 17368424
Ref: Up-regulation of S100P expression by non-steroidal anti-inflammatory drugs and its role in anti-tumorigenic effects.
PMID: 19073601
Ref: Endoplasmic reticulum stress contributes to vitamin E succinate-induced apoptosis in human gastric cancer SGC-7901 cells.
PMID: 20435408
Ref: Recombinant Lz-8 from Ganoderma lucidum induces endoplasmic reticulum stress-mediated autophagic cell death in SGC-7901 human gastric cancer cells.
PMID: 22179718
Ref: Activating transcription factor 4 confers a multidrug resistance phenotype to gastric cancer cells through transactivation of SIRT1 expression.
PMID: 22363646
Ref: Tanshinone IIA inhibits human gastric carcinoma AGS cell growth by decreasing BiP, TCTP, Mcl1 and BclxL and increasing Bax and CHOP protein expression.
PMID: 25270224
Ref: The unfolded protein response potentiates epithelial-to-mesenchymal transition (EMT) of gastric cancer cells under severe hypoxic conditions.
PMID: 25502090
Ref: Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis.
PMID: 26774454
Ref: [Expression of LXR-beta in human gastric cancer tissue and the effect of GW3965 on the proliferation of gastric cancer cell line SGC-7901].
PMID: 26932209
Ref: The transcription factor p8 regulates autophagy during diapause embryo formation in Artemia parthenogenetica.
PMID: 27125785
Ref: Nobiletin Induces Protective Autophagy Accompanied by ER-Stress Mediated Apoptosis in Human Gastric Cancer SNU-16 Cells.
PMID: 27428937
Ref: Mitochondrial dysfunction enhances cisplatin resistance in human gastric cancer cells via the ROS-activated GCN2-eIF2alpha-ATF4-xCT pathway.
PMID: 27708226
Ref: Diterpenoid Tanshinones, the extract from Danshen (Radix Salviae Miltiorrhizae) induced apoptosis in nine human cancer cell lines.
PMID: 28459519
Ref: E platinum, a newly synthesized platinum compound, induces apoptosis through ROS-triggered ER stress in gastric carcinoma cells.
PMID: 27061377
Ref: Sodium Channel Subunit SCNN1B Suppresses Gastric Cancer Growth and Metastasis via GRP78 Degradation.
PMID: 28202509
Ref: 7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2alpha/ATF4/CHOP Signaling Pathway.
PMID: 29587440
Ref: Induction of ER Stress-Mediated Apoptosis by the Major Component 5,7,4'-Trimethoxyflavone Isolated from Kaempferia parviflora Tea Infusion.
PMID: 30273054
Ref: Proviral insertion in murine lymphomas 2 promotes stomach cancer progression by regulating apoptosis via reactive oxygen species-triggered endoplasmic reticulum stress.
PMID: 30340823
Ref: Activated Integrated Stress Response Induced by Salubrinal Promotes Cisplatin Resistance in Human Gastric Cancer Cells via Enhanced xCT Expression and Glutathione Biosynthesis.
PMID: 30380689