Primary Site >> Colorectal Cancer
Gene >> ATF3
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Ref: Inhibitory effect of ATF3 antisense oligonucleotide on ectopic growth of HT29 human colon cancer cells. PMID: 10965025 Ref: Expression of the ATF3 gene on cell lines and surgically excised specimens. PMID: 11341467 |
Ref: ATF3 gene regulates cell form and migration potential of HT29 colon cancer cells. PMID: 11589305 |
Ref: Gene modulation by Cox-1 and Cox-2 specific inhibitors in human colorectal carcinoma cancer cells. PMID: 14633654 Ref: Epicatechin gallate-induced expression of NAG-1 is associated with growth inhibition and apoptosis in colon cancer cells. PMID: 15308587 |
Ref: Indole-3-carbinol and 3,3'-diindolylmethane induce expression of NAG-1 in a p53-independent manner. PMID: 15670751 Ref: The anti-invasive activity of cyclooxygenase inhibitors is regulated by the transcription factor ATF3 (activating transcription factor 3). PMID: 15897233 Ref: Transcriptional regulation of activating transcription factor 3 involves the early growth response-1 gene. PMID: 16079301 |
Ref: Conjugated linoleic acid stimulates an anti-tumorigenic protein NAG-1 in an isomer specific manner. PMID: 16286461 Ref: Activating transcription factor 3 and early growth response 1 are the novel targets of LY294002 in a phosphatidylinositol 3-kinase-independent pathway. PMID: 16489044 Ref: Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery. PMID: 16709241 Ref: The tumor metastasis suppressor gene Drg-1 down-regulates the expression of activating transcription factor 3 in prostate cancer. PMID: 17178897 |
Ref: Green tea catechin (-)-epicatechin gallate induces tumour suppressor protein ATF3 via EGR-1 activation. PMID: 17764926 Ref: Berberine, a natural isoquinoline alkaloid, induces NAG-1 and ATF3 expression in human colorectal cancer cells. PMID: 17964072 |
Ref: Amino acid limitation induces down-regulation of WNT5a at transcriptional level. PMID: 19063862 Ref: Macrophage inhibitory cytokine-1 (MIC-1) and subsequent urokinase-type plasminogen activator mediate cell death responses by ribotoxic anisomycin in HCT-116 colon cancer cells. PMID: 19540205 |
Ref: Apoptotic sensitivity of colon cancer cells to histone deacetylase inhibitors is mediated by an Sp1/Sp3-activated transcriptional program involving immediate-early gene induction. PMID: 20068171 Ref: NSAID-activated gene-1 as a molecular target for capsaicin-induced apoptosis through a novel molecular mechanism involving GSK3beta, C/EBPbeta and ATF3. PMID: 20110283 Ref: The integrated stress response-associated signals modulates intestinal tumor cell growth by NSAID-activated gene 1 (NAG-1/MIC-1/PTGF-beta). PMID: 20130018 Ref: Activating transcription factor 2 (ATF2) controls tolfenamic acid-induced ATF3 expression via MAP kinase pathways. PMID: 20581861 Ref: Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibition. PMID: 21129190 Ref: In vitro anti-proliferative activity of alcoholic stem extract of Coscinium fenestratum in human colorectal cancer cells. PMID: 23136612 |
Ref: Resveratrol-induced apoptosis is mediated by early growth response-1, Kruppel-like factor 4, and activating transcription factor 3. PMID: 21205742 Ref: The dietary compounds resveratrol and genistein induce activating transcription factor 3 while suppressing inhibitor of DNA binding/differentiation-1. PMID: 21554132 Ref: COX-2 gene expression in colon cancer tissue related to regulating factors and promoter methylation status. PMID: 21668942 |
Ref: Key role of ATF3 in p53-dependent DR5 induction upon DNA damage of human colon cancer cells. PMID: 21927023 Ref: Patulin induces colorectal cancer cells apoptosis through EGR-1 dependent ATF3 up-regulation. PMID: 22230687 Ref: Inhibition of GSK-3beta reverses the pro-apoptotic effect of proadifen (SKF-525A) in HT-29 colon adenocarcinoma cells. PMID: 22683934 |
Ref: 3,3'-diindolylmethane induces activating transcription factor 3 (ATF3) via ATF4 in human colorectal cancer cells. PMID: 22819556 Ref: Hydroxytyrosyl ethyl ether exhibits stronger intestinal anticarcinogenic potency and effects on transcript profiles compared to hydroxytyrosol. PMID: 23411228 Ref: Anticancer activity of olive oil hydroxytyrosyl acetate in human adenocarcinoma Caco-2 cells. PMID: 23452288 Ref: Reactive oxygen species mediate tolfenamic acid-induced apoptosis in human colorectal cancer cells. PMID: 23896517 Ref: 15,16-Dihydrotanshinone I-induced apoptosis in human colorectal cancer cells: involvement of ATF3. PMID: 23898083 |
Ref: Nonsteroidal anti-inflammatory drug activated gene-1 (NAG-1) modulators from natural products as anti-cancer agents. PMID: 24530873 Ref: Role of ATF3 in synergistic cancer cell killing by a combination of HDAC inhibitors and agonistic anti-DR5 antibody through ER stress in human colon cancer cells. PMID: 24530917 Ref: Activating transcription factor 3 promotes colon cancer metastasis. PMID: 24859834 Ref: Role of activating transcription factor 3 (ATF3) in endoplasmic reticulum (ER) stress-induced sensitization of p53-deficient human colon cancer cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through up-re PMID: 24939851 Ref: Anti-inflammatory and anti-cancer activity of mulberry (Morus alba L.) root bark. PMID: 24962785 Ref: Enhanced anti-colorectal cancer effects of carfilzomib combined with CPT-11 via downregulation of nuclear factor-kappaB in vitro and in vivo. PMID: 24968890 Ref: Anti-cancer activity of Ginger (Zingiber officinale) leaf through the expression of activating transcription factor 3 in human colorectal cancer cells. PMID: 25338635 Ref: The contribution of activating transcription factor 3 to apoptosis of human colorectal cancer cells by protocatechualdehyde, a naturally occurring phenolic compound. PMID: 25447816 Ref: The induction of activating transcription factor 3 (ATF3) contributes to anti-cancer activity of Abeliophyllum distichum Nakai in human colorectal cancer cells. PMID: 25494848 |
Ref: ATF3 Mediates Anti-Cancer Activity of Trans-10, cis-12-Conjugated Linoleic Acid in Human Colon Cancer Cells. PMID: 25767681 |
Ref: Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis. PMID: 26637668 Ref: Naringenin-Mediated ATF3 Expression Contributes to Apoptosis in Human Colon Cancer. PMID: 26797111 Ref: Resveratrol-induced transcriptional up-regulation of ASMase (SMPD1) of human leukemia and cancer cells. PMID: 26809095 Ref: Potential Dual Role of Activating Transcription Factor 3 in Colorectal Cancer. PMID: 26851004 Ref: Acquisition of Chemoresistance and Other Malignancy-related Features of Colorectal Cancer Cells Are Incremented by Ribosome-inactivating Stress. PMID: 26961878 Ref: In Vitro Anticancer Activity of Phlorofucofuroeckol A via Upregulation of Activating Transcription Factor 3 against Human Colorectal Cancer Cells. PMID: 27043582 Ref: ASBEL-TCF3 complex is required for the tumorigenicity of colorectal cancer cells. PMID: 27791078 |
Ref: Murine MTHFD1-synthetase deficiency, a model for the human MTHFD1 R653Q polymorphism, decreases growth of colorectal tumors. PMID: 27597531 Ref: Kahweol from Coffee Induces Apoptosis by Upregulating Activating Transcription Factor 3 in Human Colorectal Cancer Cells. PMID: 27871156 Ref: Influence of components of tumour microenvironment on the response of HCT-116 colorectal cancer to the ruthenium-based drug NAMI-A. PMID: 28064102 Ref: Overexpression of the transcription factor ATF3 with a regulatory molecular signature associates with the pathogenic development of colorectal cancer. PMID: 28402947 Ref: Vitex rotundifolia Fruit Extract Induces Apoptosis Through the Downregulation of ATF3-Mediated Bcl-2 Expression in Human Colorectal Cancer Cells. PMID: 28468511 Ref: ATF3 Repression of BCL-XL Determines Apoptotic Sensitivity to HDAC Inhibitors across Tumor Types. PMID: 28611196 |
Ref: Novel evidence for a PIWI-interacting RNA (piRNA) as an oncogenic mediator of disease progression, and a potential prognostic biomarker in colorectal cancer. PMID: 29382334 Ref: Cytotoxic activity of the twigs of Cinnamomum cassia through the suppression of cell proliferation and the induction of apoptosis in human colorectal cancer cells. PMID: 29554905 Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 Ref: The stress response gene ATF3 is a direct target of the Wnt/beta-catenin pathway and inhibits the invasion and migration of HCT116 human colorectal cancer cells. PMID: 29966001 Ref: Serum and Adipose Tissue mRNA Levels of ATF3 and FNDC5/Irisin in Colorectal Cancer Patients With or Without Obesity. PMID: 30246803 |