Primary Site >> Stomach Cancer
Gene >> ASCL2
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Ref: Aberrant upregulation of ASCL2 by promoter demethylation promotes the growth and resistance to 5-fluorouracil of gastric cancer cells. PMID: 23181270 Ref: Distribution of LGR5+ cells and associated implications during the early stage of gastric tumorigenesis. PMID: 24340024 |
Ref: SMYD3 controls a Wnt-responsive epigenetic switch for ASCL2 activation and cancer stem cell maintenance. PMID: 29746925 Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 Ref: ASCL2 expression contributes to gastric tumor migration and invasion by downregulating miR223 and inducing EMT. PMID: 30106147 |