Primary Site >> Colorectal Cancer
Gene >> ARHGEF2
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Ref: Selective cytotoxicity of a bicyclic Ras inhibitor in cancer cells expressing K-Ras(G13D). PMID: 19540195 |
Ref: Rgnef (p190RhoGEF) knockout inhibits RhoA activity, focal adhesion establishment, and cell motility downstream of integrins. PMID: 22649559 Ref: Gef gene therapy enhances the therapeutic efficacy of cytotoxics in colon cancer cells. PMID: 22770988 |
Ref: A novel double-enhanced suicide gene therapy in a colon cancer cell line mediated by gef and apoptin. PMID: 23921576 |
Ref: Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling. PMID: 26126266 |
Ref: Synergistic induction of apoptosis by salinomycin and gefitinib through lysosomal and mitochondrial dependent pathway overcomes gefitinib resistance in colorectal cancer. PMID: 26461472 Ref: Induced cortical tension restores functional junctions in adhesion-defective carcinoma cells. PMID: 29184140 |