Primary Site >> Colorectal Cancer

Gene >> APOB

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Ref: Biosynthetic precursor (214 kDa) of apolipoprotein B-48 is not secreted by Caco-2 cells and normal human intestine.
PMID: 2604723
Ref: Similarities and differences in the function of regulatory elements at the 5' end of the human apolipoprotein B gene in cultured hepatoma (HepG2) and colon carcinoma (CaCo-2) cells.
PMID: 1660892
Ref: Nuclease-hypersensitive sites define a region with enhancer activity in the third intron of the human apolipoprotein B gene.
PMID: 1527004
Ref: The mechanism by which the human apolipoprotein B gene reducer operates involves blocking of transcriptional activation by hepatocyte nuclear factor 3.
PMID: 8441395
Ref: Increased expression of apolipoprotein genes accompanies differentiation in the intestinal cell line Caco-2.
PMID: 8516325
Ref: Caco-2 cells as a model for intestinal lipoprotein synthesis and secretion.
PMID: 7768354
Ref: Assembly and secretion of VLDL in nondifferentiated Caco-2 cells stably transfected with human recombinant ApoB48 cDNA.
PMID: 9409282
Ref: Apolipoprotein B, a paradigm for proteins regulated by intracellular degradation, does not undergo intracellular degradation in CaCo2 cells.
PMID: 10660549
Ref: Apobec-1 transcription in rat colon cancer: decreased apobec-1 protein production through alterations in polysome distribution and mRNA translation associated with upstream AUGs.
PMID: 12020819
Ref: Chronic but not acute treatment with conjugated linoleic acid (CLA) isomers (trans-10, cis-12 CLA and cis-9, trans-11 CLA) affects lipid metabolism in Caco-2 cells.
PMID: 12163657
Ref: Inhibiting proteasomal degradation of microsomal triglyceride transfer protein prevents CCl4-induced steatosis.
PMID: 17405876
Ref: Mechanisms involved in vitamin E transport by primary enterocytes and in vivo absorption.
PMID: 17582142
Ref: Tissue expression of glycated apolipoprotein B in colorectal adenoma and cancer.
PMID: 21378338
Ref: Blood lipid and lipoprotein concentrations and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition.
PMID: 21383385
Ref: Serum Lipids and the Risk of Gastrointestinal Malignancies in the Swedish AMORIS Study.
PMID: 22969802
Ref: [Experimental study of the impact of hyperlipidemia on the chemotherapy in colorectal cancer model].
PMID: 23801216
Ref: Effect of onion flavonoids on colorectal cancer with hyperlipidemia: an in vivo study.
PMID: 24470761
Ref: Lipid levels in serum and cancerous tissues of colorectal cancer patients.
PMID: 25024621
Ref: Apolipoproteins, lipids and risk of cancer.
PMID: 26804063
Ref: Predictive value of chemotherapy-related high-density lipoprotein cholesterol (HDL) elevation in patients with colorectal cancer receiving adjuvant chemotherapy: an exploratory analysis of 851 cases.
PMID: 27344180
Ref: Decreased serum apolipoprotein A1 levels are associated with poor survival and systemic inflammatory response in colorectal cancer.
PMID: 28710487
Ref: Blood lipids and lipoproteins in relation to incidence and mortality risks for CVD and cancer in the prospective EPIC-Heidelberg cohort.
PMID: 29254484
Ref: Intestinal microorganisms involved in colorectal cancer complicated with dyslipidosis.
PMID: 30239257