Primary Site >> Stomach Cancer

Gene >> APEX1

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Ref: A gene encoding an apurinic/apyrimidinic endonuclease-like protein is up-regulated in human gastric cancer.
PMID: 12800223
 Ref: Expression of apurinic/apyrimidinic endonuclease-1 (APE-1) in H. pylori-associated gastritis, gastric adenoma, and gastric cancer.
PMID: 18466396
Ref: Celecoxib inhibits apurinic/apyrimidinic endonuclease-1 expression and prevents gastric cancer in Helicobacter pylori-infected mongolian gerbils.
PMID: 18987470
 Ref: Association between genetic polymorphisms of DNA base excision repair genes and evolution of precancerous gastric lesions in a Chinese population.
PMID: 19147860
 Ref: Dual regulation by apurinic/apyrimidinic endonuclease-1 inhibits gastric epithelial cell apoptosis during Helicobacter pylori infection.
PMID: 20332233
Ref: Possible associations of APE1 polymorphism with susceptibility and HOGG1 polymorphism with prognosis in gastric cancer.
PMID: 20530453
Ref: Polymorphic DNA repair and metabolic genes: a multigenic study on gastric cancer.
PMID: 20817763
 Ref: DNA repair gene and MTHFR gene polymorphisms as prognostic markers in locally advanced adenocarcinoma of the esophagus or stomach treated with cisplatin and 5-fluorouracil-based neoadjuvant chemotherapy.
PMID: 21347786
Ref: A genetic variation in APE1 is associated with gastric cancer survival in a Chinese population.
PMID: 21615620
Ref: The DNA repair gene APE1 T1349G polymorphism and risk of gastric cancer in a Chinese population.
PMID: 22205985
 Ref: Helicobacter pylori genotype and polymorphisms in DNA repair enzymes: where do they correlate in gastric cancer?
PMID: 22374853
 Ref: APEX nuclease (multifunctional DNA repair enzyme) 1 gene Asp148Glu polymorphism and cancer risk: a meta-analysis involving 58 articles and 48903 participants.
PMID: 24349526
 Ref: Upregulation of PD-L1 and APE1 is associated with tumorigenesis and poor prognosis of gastric cancer.
PMID: 25733810
Ref: Relationship between apurinic endonuclease 1 Asp148Glu polymorphism and gastrointestinal cancer risk: An updated meta-analysis.
PMID: 25945024
Ref: Polymorphisms in NEIL-2, APE-1, CYP2E1 and MDM2 Genes are Independent Predictors of Gastric Cancer Risk in a Northern Jiangsu Population (China).
PMID: 26373042
Ref: Association between polymorphisms in APE1 and XRCC1 and the risk of gastric cancer in Korean population.
PMID: 26379967
 Ref: AT101 exerts a synergetic efficacy in gastric cancer patients with 5-FU based treatment through promoting apoptosis and autophagy.
PMID: 27144437
 Ref: Prediction of Lymph Node Metastases in Gastric Cancer by Serum APE1 Expression.
PMID: 28638465